Search Results - "SILVA, DANIELA NASCIMENTO"
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Bone marrow-derived mesenchymal stem/stromal cells reverse the sensorial diabetic neuropathy via modulation of spinal neuroinflammatory cascades
Published in Journal of neuroinflammation (22-06-2018)“…Diabetic neuropathy (DN) is a frequent and debilitating manifestation of diabetes mellitus, to which there are no effective therapeutic approaches. Mesenchymal…”
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Circulating miRNAs as Potential Biomarkers Associated with Cardiac Remodeling and Fibrosis in Chagas Disease Cardiomyopathy
Published in International journal of molecular sciences (20-08-2019)“…Chagas disease (CD) affects approximately 6-7 million people worldwide, from which 30% develop chronic Chagas cardiomyopathy (CCC), usually after being…”
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Dimensional error of selective laser sintering, three-dimensional printing and PolyJet™ models in the reproduction of mandibular anatomy
Published in Journal of cranio-maxillo-facial surgery (01-04-2009)“…Summary Background Selective laser sintering (SLS), three-dimensional printing (3DP™) and PolyJet™ are rapid prototyping (RP) techniques to fabricate…”
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Conditioned Medium of Bone Marrow-Derived Mesenchymal Stromal Cells as a Therapeutic Approach to Neuropathic Pain: A Preclinical Evaluation
Published in Stem cells international (01-01-2018)“…Neuropathic pain is a type of chronic pain caused by injury or dysfunction of the nervous system, without effective therapeutic approaches. Mesenchymal stromal…”
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IGF-1 overexpression improves mesenchymal stem cell survival and promotes neurological recovery after spinal cord injury
Published in Stem cell research & therapy (21-05-2019)“…Survival and therapeutic actions of bone marrow-derived mesenchymal stem cells (BMMSCs) can be limited by the hostile microenvironment present during acute…”
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Dimensional error in selective laser sintering and 3D-printing of models for craniomaxillary anatomy reconstruction
Published in Journal of cranio-maxillo-facial surgery (01-12-2008)“…Summary Background Selective laser sintering (SLS) and three-dimensional printing (3DP™) are rapid prototyping (RP) techniques to fabricate prototypes from…”
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7
Clinical Trials Using Mesenchymal Stem Cells for Spinal Cord Injury: Challenges in Generating Evidence
Published in Cells (Basel, Switzerland) (17-03-2022)“…Spinal cord injury (SCI) remains an important public health problem which often causes permanent loss of muscle strength, sensation, and function below the…”
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Phenotype instability of hepatocyte-like cells produced by direct reprogramming of mesenchymal stromal cells
Published in Stem cell research & therapy (10-04-2020)“…Hepatocyte-like cells (iHEPs) generated by transcription factor-mediated direct reprogramming of somatic cells have been studied as potential cell sources for…”
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Therapeutic effects of sphingosine kinase inhibitor N,N-dimethylsphingosine (DMS) in experimental chronic Chagas disease cardiomyopathy
Published in Scientific reports (21-07-2017)“…Chagas disease cardiomyopathy is a parasite-driven inflammatory disease to which there are no effective treatments. Here we evaluated the therapeutic potential…”
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A Novel High-Content Screening-Based Method for Anti-Trypanosoma cruzi Drug Discovery Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Published in Stem cells international (15-08-2021)“…Chagas disease is caused by Trypanosoma cruzi infection and remains a relevant cause of chronic heart failure in Latin America. The pharmacological arsenal for…”
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Galectin-3 Knockdown Impairs Survival, Migration, and Immunomodulatory Actions of Mesenchymal Stromal Cells in a Mouse Model of Chagas Disease Cardiomyopathy
Published in Stem cells international (01-01-2017)“…Therapies based on transplantation of mesenchymal stromal cells (MSC) hold promise for the management of inflammatory disorders. In chronic Chagas disease…”
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12
Evaluation of two formulations containing mineral trioxide aggregate on delayed tooth replantation : relevance of RANKL / RANK / OPG system
Published in Odontology (01-05-2016)“…[Abstract] This study aimed to evaluate the effects of White MTA (WMTA) and MTA Fillapex(R) on root resorption, when used for root canal filling, in a rat…”
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Assessment of syndecan-4 expression in the hearts of Trypanosoma cruzi-infected mice and human subjects with chronic Chagas disease cardiomyopathy
Published in Surgical and experimental pathology (10-12-2018)“…Background Chronic Chagas cardiomyopathy (CCC) is characterized by the presence of a multifocal inflammatory response and myocardial damage, leading to…”
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Clinical and echocardiographic characteristics after six months of sacubitril/valsartan in Chagas heart disease – A case series
Published in British journal of clinical pharmacology (01-02-2022)“…Chagas cardiomyopathy is the most prevalent non‐ischaemic cardiomyopathy in Latin America, with high morbidity and mortality even today. Treatment of these…”
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T-Cell Receptor Repertoire Sequencing and Its Applications: Focus on Infectious Diseases and Cancer
Published in International journal of molecular sciences (01-08-2022)“…The immune system is a dynamic feature of each individual and a footprint of our unique internal and external exposures. Indeed, the type and level of exposure…”
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Liquid Biopsy in Hepatocellular Carcinoma: Opportunities and Challenges for Immunotherapy
Published in Cancers (27-08-2021)“…Hepatocellular carcinoma (HCC) is one of the deadliest cancer types worldwide. HCC is often diagnosed at a late stage when the therapeutic options are very…”
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Genetic Engineering as a Strategy to Improve the Therapeutic Efficacy of Mesenchymal Stem/Stromal Cells in Regenerative Medicine
Published in Frontiers in cell and developmental biology (21-08-2020)“…Mesenchymal stem/stromal cells (MSCs) have been widely studied in the field of regenerative medicine for applications in the treatment of several disease…”
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Effect of GaAlAs low-level laser therapy on mouth opening after orthognathic surgery
Published in Lasers in medical science (01-08-2018)“…To evaluate low-level laser therapy (LLLT) as an adjunct to enhance postoperative mouth opening after orthognathic surgery. Prospective clinical trial of 82…”
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Association of Cardiac Galectin-3 Expression, Myocarditis, and Fibrosis in Chronic Chagas Disease Cardiomyopathy
Published in The American journal of pathology (01-05-2017)“…Chronic Chagas disease cardiomyopathy, caused by Trypanosoma cruzi infection, is a major cause of heart failure in Latin America. Galectin-3 (Gal-3) has been…”
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Arming Mesenchymal Stromal/Stem Cells Against Cancer: Has the Time Come?
Published in Frontiers in pharmacology (29-09-2020)“…Since mesenchymal stromal/stem cells (MSCs) were discovered, researchers have been drawn to study their peculiar biological features, including their immune…”
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