Search Results - "SIGMUNDSSON, Thordur"

A Genetic Risk Factor for Periodic Limb Movements in Sleep by Stefansson, Hreinn, Stefansson, Kari, Rye, David B, Hicks, Andrew, Petursson, Hjorvar, Ingason, Andres, Thorgeirsson, Thorgeir E, Palsson, Stefan, Sigmundsson, Thordur, Sigurdsson, Albert P, Eiriksdottir, Ingibjorg, Soebech, Emilia, Bliwise, Donald, Beck, Joseph M, Rosen, Ami, Waddy, Salina, Trotti, Lynn M, Iranzo, Alex, Thambisetty, Madhav, Hardarson, Gudmundur A, Kristjansson, Kristleifur, Gudmundsson, Larus J, Thorsteinsdottir, Unnur, Kong, Augustine, Gulcher, Jeffrey R, Gudbjartsson, Daniel

“…Genetic analyses of Icelandic and North American subjects with periodic leg movements and restless legs syndrome implicate a genetic susceptibility variant…”
Get full text

Distribution of symptom dimensions across Kraepelinian divisions by Dikeos, Dimitris G., Wickham, Harvey, McDonald, Colm, Walshe, Muriel, Sigmundsson, Thordur, Bramon, Elvira, Grech, Anton, Toulopoulou, Timothea, Murray, Robin, Sham, Pak C.

“…Dimensional structures are established for many psychiatric diagnoses, but dimensions have not been compared between diagnostic groups. To examine the…”
Get full text

Correlates of PLMs variability over multiple nights and impact upon RLS diagnosis by Trotti, Lynn Marie, Bliwise, Donald L, Greer, Sophia A, Sigurdsson, Albert P, Gudmundsdóttir, Gudbjörg Birna, Wessel, Thomas, Organisak, Lisa M, Sigthorsson, Thor, Kristjansson, Kristleifur, Sigmundsson, Thordur, Rye, David B

“…Abstract Objective Night-to-night variability of periodic leg movements (PLMs) in restless legs syndrome (RLS) was examined to define the range of…”
Get full text

Genomewide Genetic Linkage Analysis Confirms the Presence of Susceptibility Loci for Schizophrenia, on Chromosomes 1q32.2, 5q33.2, and 8p21-22 and Provides Support for Linkage to Schizophrenia, on Chromosomes 11q23.3-24 and 20q12.1-11.23 by Gurling, Hugh M.D., Kalsi, Gursharan, Brynjolfson, Jon, Sigmundsson, Thordur, Sherrington, Robin, Mankoo, Baljinder S., Read, Timothy, Murphy, Patrice, Blaveri, Ekaterina, McQuillin, Andrew, Petursson, Hannes, Curtis, David

“…We have performed genetic linkage analysis in 13 large multiply affected families, to test the hypothesis that there is extensive heterogeneity of linkage for…”
Get full text

Support for involvement of the AHI1 locus in schizophrenia by INGASON, Andres, SIGMUNDSSON, Thordur, STEFANSSON, Kari, PETURSSON, Hannes, STEFANSSON, Hreinn, STEINBERG, Stacy, SIGURDSSON, Engilbert, HARALDSSON, Magnus, MAGNUSDOTTIR, Brynja B, FRIGGE, Michael L, KONG, Augustine, GULCHER, Jeffrey, THORSTEINSDOTTIR, Unnur

Get full text

Large recurrent microdeletions associated with schizophrenia by Tosato, Sarah, Peltonen, Leena, Kiemeney, Lambertus A, Nöthen, Markus M, Sigurdsson, Asgeir, Fraser, Gillian, Sigmundsson, Thordur, Ophoff, Roel A, Ullum, Henrik, Li, Tao, Stefansson, Kari, Bramon, Elvira, Djurovic, Srdjan, Walshe, Muriel, Bjornsson, Asgeir, Suvisaari, Jaana, Gylfason, Arnaldur, Tuulio-Henriksson, Annamarie, Sabatti, Chiara, Andreassen, Ole A, Kong, Augustine, Collier, David A, Ingason, Andres, Sigurdsson, Engilbert, Jonasdottir, Adalbjorg, Haraldsson, Magnus, Pietiläinen, Olli P. H, Walker, Nicholas, Hartmann, Annette, Halldorsson, Bjarni V, St Clair, David, Ruggeri, Mirella, Vasilescu, Catalina, Need, Anna C, Jakobsen, Klaus D, Gudbjartsson, Daniel, Di Forti, Marta, Melle, Ingrid, Toulopoulou, Timi, Mühleisen, Thomas W, Jonasdottir, Aslaug, Stefansson, Hreinn, Franke, Barbara, Steinberg, Stacy, Blondal, Thorarinn, Rietschel, Marcella, Vassos, Evangelos, Rujescu, Dan, Buizer-Voskamp, Jacobine E, Goldstein, David B, Cichon, Sven, Freimer, Nelson B, Petursson, Hannes, Werge, Thomas, Magnusdottir, Brynja B, Murray, Robin, Francks, Clyde, Gulcher, Jeffrey R, Crombie, Caroline, Giegling, Ina, Möller, Hans-Jürgen, Wang, August G, Hansen, Thomas, Olesen, Jes, Paunio, Tiina, Thorsteinsdottir, Unnur, Lonnqvist, Jouko, Shianna, Kevin V, Georgi, Alexander, Ge, Dongliang, Mattiasdottir, Sigurborg, Thorgeirsson, Thorgeir E, Matthews, Paul M, Fossdal, Ragnheidur, Muglia, Pierandrea

“…Reduced fecundity, associated with severe mental disorders, places negative selection pressure on risk alleles and may explain, in part, why common variants…”
Get full text

Disruption of the neurexin 1 gene is associated with schizophrenia by Rujescu, Dan, Ingason, Andres, Cichon, Sven, Pietiläinen, Olli P.H., Barnes, Michael R., Toulopoulou, Timothea, Picchioni, Marco, Vassos, Evangelos, Ettinger, Ulrich, Bramon, Elvira, Murray, Robin, Ruggeri, Mirella, Tosato, Sarah, Bonetto, Chiara, Steinberg, Stacy, Sigurdsson, Engilbert, Sigmundsson, Thordur, Petursson, Hannes, Gylfason, Arnaldur, Olason, Pall I., Hardarsson, Gudmundur, Jonsdottir, Gudrun A., Gustafsson, Omar, Fossdal, Ragnheidur, Giegling, Ina, Möller, Hans-Jürgen, Hartmann, Annette M., Hoffmann, Per, Crombie, Caroline, Fraser, Gillian, Walker, Nicholas, Lonnqvist, Jouko, Suvisaari, Jaana, Tuulio-Henriksson, Annamari, Djurovic, Srdjan, Melle, Ingrid, Andreassen, Ole A., Hansen, Thomas, Werge, Thomas, Kiemeney, Lambertus A., Franke, Barbara, Veltman, Joris, Buizer-Voskamp, Jacobine E., Sabatti, Chiara, Ophoff, Roel A., Rietschel, Marcella, Nöthen, Markus M., Stefansson, Kari, Peltonen, Leena, St Clair, David, Stefansson, Hreinn, Collier, David A.

“…Deletions within the neurexin 1 gene (NRXN1; 2p16.3) are associated with autism and have also been reported in two families with schizophrenia. We examined…”
Get full text

Structural MRI correlates of apathy symptoms in older persons without dementia: AGES-Reykjavik Study by Grool, Anne M, Geerlings, Mirjam I, Sigurdsson, Sigurdur, Eiriksdottir, Gudny, Jonsson, Palmi V, Garcia, Melissa E, Siggeirsdottir, Kristin, Harris, Tamara B, Sigmundsson, Thordur, Gudnason, Vilmundur, Launer, Lenore J

“…OBJECTIVE:We aimed to investigate the relation between apathy symptoms and structural brain changes on MRI, including white matter lesions (WMLs) and atrophy,…”
Get full text

Neuregulin 1 and Susceptibility to Schizophrenia by Stefansson, Hreinn, Petursson, Hannes, Sigurdsson, Engilbert, Steinthorsdottir, Valgerdur, Bjornsdottir, Soley, Sigmundsson, Thordur, Ghosh, Shyamali, Brynjolfsson, Jon, Gunnarsdottir, Steinunn, Ivarsson, Omar, Chou, Thomas T., Hjaltason, Omar, Birgisdottir, Birgitta, Jonsson, Helgi, Gudnadottir, Vala G., Gudmundsdottir, Elsa, Bjornsson, Asgeir, Ingvarsson, Brynjolfur, Ingason, Andres, Sigfusson, Sigmundur, Hardardottir, Hronn, Harvey, Richard P., Lai, Donna, Zhou, Mingdong, Brunner, Daniela, Mutel, Vincent, Gonzalo, Acuna, Lemke, Greg, Sainz, Jesus, Johannesson, Gardar, Andresson, Thorkell, Gudbjartsson, Daniel, Manolescu, Andrei, Frigge, Michael L., Gurney, Mark E., Kong, Augustine, Gulcher, Jeffrey R., Stefansson, Kari

“…The cause of schizophrenia is unknown, but it has a significant genetic component. Pharmacologic studies, studies of gene expression in man, and studies of…”
Get full text

Large genome-wide association study identifies three novel risk variants for restless legs syndrome by Didriksen, Maria, Nawaz, Muhammad Sulaman, Dowsett, Joseph, Bell, Steven, Erikstrup, Christian, Pedersen, Ole B., Sørensen, Erik, Jennum, Poul J., Burgdorf, Kristoffer S., Burchell, Brendan, Butterworth, Adam S., Soranzo, Nicole, Rye, David B., Trotti, Lynn Marie, Saini, Prabhjyot, Stefansdottir, Lilja, Magnusson, Sigurdur H., Thorleifsson, Gudmar, Sigmundsson, Thordur, Sigurdsson, Albert P., Van Den Hurk, Katja, Quee, Franke, Tanck, Michael W. T., Ouwehand, Willem H., Roberts, David J., Earley, Eric J., Busch, Michael P., Mast, Alan E., Page, Grier P., Danesh, John, Di Angelantonio, Emanuele, Stefansson, Hreinn, Ullum, Henrik, Stefansson, Kari

“…Restless legs syndrome (RLS) is a common neurological sensorimotor disorder often described as an unpleasant sensation associated with an urge to move the…”
Get full text

Brain anatomy and sensorimotor gating in Asperger’s syndrome by McAlonan, Grainne M., Daly, Eileen, Kumari, Veena, Critchley, Hugo D., Amelsvoort, Therese van, Suckling, John, Simmons, Andrew, Sigmundsson, Thordur, Greenwood, Kathyrn, Russell, Ailsa, Schmitz, Nicole, Happe, Francesca, Howlin, Patricia, Murphy, Declan G. M.

“…Asperger’s syndrome (an autistic disorder) is characterized by stereotyped and obsessional behaviours, and pervasive abnormalities in socio‐emotional and…”
Get full text

Structural MRI correlates of apathy symptoms in older persons without dementia by Grool, Anne M, Geerlings, Mirjam I, Sigurdsson, Sigurdur, Eiriksdottir, Gudny, Jonsson, Palmi V, Garcia, Melissa E, Siggeirsdottir, Kristin, Harris, Tamara B, Sigmundsson, Thordur, Gudnason, Vilmundur, Launer, Lenore J

“…Objective: We aimed to investigate the relation between apathy symptoms and structural brain changes on MRI, including white matter lesions (WMLs) and atrophy,…”
Get full text

Structural Abnormalities in Frontal, Temporal, and Limbic Regions and Interconnecting White Matter Tracts in Schizophrenic Patients With Prominent Negative Symptoms by Sigmundsson, Thordur, Suckling, John, Maier, Michael, Williams, Steven C.R., Bullmore, Edward T., Greenwood, Kathryn E., Fukuda, Rimmei, Ron, Maria A., Toone, Brian K.

“…OBJECTIVE: Imaging studies of schizophrenia have repeatedly demonstrated global abnormalities of cerebral and ventricular volumes. However, pathological…”
Get full text

Tower of London versus real life analogue planning in schizophrenia with disorganization and psychomotor poverty symptoms by Greenwood, Kathryn E, Wykes, Til, Sigmundsson, Thordur, Landau, Sabine, Morris, Robin G

“…Neuropsychological models propose qualitatively distinct planning impairments in the psychomotor poverty and disorganization syndromes in schizophrenia. It was…”
Get more information

Executive functioning in schizophrenia and the relationship with symptom profile and chronicity by Greenwood, Kathryn E, Morris, Robin, Sigmundsson, Thordur, Landau, Sabine, Wykes, Til

“…This study reports the executive function profile in people with schizophrenia, with a simultaneous comparison of chronicity and of those with predominately…”
Get more information

Eye movement deficits in schizophrenia: Investigation of a genetically homogenous Icelandic sample by Haraldsson, H. Magnus, Ettinger, Ulrich, Magnusdottir, Brynja B., Sigmundsson, Thordur, Sigurdsson, Engilbert, Petursson, Hannes

“…Background Deficits in antisaccade (AS) and smooth pursuit eye movements (SPEM) are promising endophenotypes in genetic studies of schizophrenia. The Icelandic…”
Get full text

COMT val(158)met genotype and smooth pursuit eye movements in schizophrenia by Haraldsson, H Magnus, Ettinger, Ulrich, Magnusdottir, Brynja B, Sigmundsson, Thordur, Sigurdsson, Engilbert, Ingason, Andres, Petursson, Hannes

“…The association between the catechol-O-methyltransferase (COMT) val(158)met polymorphism (rs4680) and smooth pursuit eye movements (SPEM) was investigated in…”
Get full text

Catechol-O-Methyltransferase Val super(158)Met Polymorphism and Antisaccade Eye Movements in Schizophrenia by Haraldsson, Haraldur Magnus, Ettinger, Ulrich, Magnusdottir, Brynja B, Sigmundsson, Thordur, Sigurdsson, Engilbert, Ingason, Andres, Petursson, Hannes

“…The catechol-O-methyltransferase (COMT) enzyme catabolizes dopamine. The val super(158)met single nucleotide polymorphism (rs4680) in the COMT gene has…”
Get full text

Support for involvement of the AHI1 locus in schizophrenia by Ingason, Andres, Sigmundsson, Thordur, Steinberg, Stacy, Sigurdsson, Engilbert, Haraldsson, Magnus, Magnusdottir, Brynja B, Frigge, Michael L, Kong, Augustine, Gulcher, Jeffrey, Thorsteinsdottir, Unnur, Stefansson, Kari, Petursson, Hannes, Stefansson, Hreinn

“…Recently, markers in the Abelson Helper Integration Site 1 (AHI1) region were shown to be associated with schizophrenia in a family sample of Israeli-Arabs…”
Get full text

Ziprasidone versus olanzapine, risperidone or quetiapine in patients with chronic schizophrenia: A 12-week open-label, multicentre clinical trial by Lublin, Henrik, Haug, Hans-joachim, Koponen, Hannu, Sigmundsson, Thordur, Kolb, Stefan A.

“…The efficacy, safety and tolerability of ziprasidone versus the comparators olanzapine, risperidone or quetiapine were investigated in adult patients with…”
Get full text