Search Results - "SIDOROV, Igor A"

Engineering potent live attenuated coronavirus vaccines by targeted inactivation of the immune evasive viral deubiquitinase by Myeni, Sebenzile K., Bredenbeek, Peter J., Knaap, Robert C. M., Dalebout, Tim J., Morales, Shessy Torres, Sidorov, Igor A., Linger, Marissa E., Oreshkova, Nadia, van Zanen-Gerhardt, Sophie, Zander, Serge A. L., Enjuanes, Luis, Sola, Isabel, Snijder, Eric J., Kikkert, Marjolein

“…Coronaviruses express a papain-like protease (PLpro) that is required for replicase polyprotein maturation and also serves as a deubiquitinating enzyme (DUB)…”
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Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies by Zhu, Zhongyu, Chakraborti, Samitabh, He, Yuxian, Roberts, Anjeanette, Sheahan, Tim, Xiao, Xiaodong, Hensley, Lisa E, Prabakaran, Ponraj, Rockx, Barry, Sidorov, Igor A, Corti, Davide, Vogel, Leatrice, Feng, Yang, Kim, Jae-Ouk, Wang, Lin-Fa, Baric, Ralph, Lanzavecchia, Antonio, Curtis, Kristopher M, Nabel, Gary J, Subbarao, Kanta, Jiang, Shibo, Dimitrov, Dimiter S

“…The severe acute respiratory syndrome coronavirus (SARS-CoV) caused a worldwide epidemic in late 2002/early 2003 and a second outbreak in the winter of…”
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Non-Toxigenic Clostridioides difficile Strain E4 (NTCD-E4) Prevents Establishment of Primary C. difficile Infection by Epidemic PCR Ribotype 027 in an In Vitro Human Gut Model by Etifa, Perezimor, Rodríguez, César, Harmanus, Céline, Sanders, Ingrid M J G, Sidorov, Igor A, Mohammed, Olufunmilayo A, Savage, Emily, Timms, Andrew R, Freeman, Jane, Smits, Wiep Klaas, Wilcox, Mark H, Baines, Simon D

“…infection (CDI) remains a significant healthcare burden. Non-toxigenic (NTCD) strains have shown a benefit in preventing porcine enteritis and in human…”
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Translating genomic exploration of the family Polyomaviridae into confident human polyomavirus detection by Kamminga, Sergio, Sidorov, Igor A., Tadesse, Michaël, van der Meijden, Els, de Brouwer, Caroline, Zaaijer, Hans L., Feltkamp, Mariet C.W., Gorbalenya, Alexander E.

“…The Polyomaviridae is a family of ubiquitous dsDNA viruses that establish persistent infection early in life. Screening for human polyomaviruses (HPyVs), which…”
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Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort by Carbo, Ellen C, Sidorov, Igor A, van Rijn-Klink, Anneloes L, Pappas, Nikos, van Boheemen, Sander, Mei, Hailiang, Hiemstra, Pieter S, Eagan, Tomas M, Claas, Eric C J, Kroes, Aloys C M, de Vries, Jutte J C

“…Viral metagenomics is increasingly applied in clinical diagnostic settings for detection of pathogenic viruses. While several benchmarking studies have been…”
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Longitudinal Monitoring of DNA Viral Loads in Transplant Patients Using Quantitative Metagenomic Next-Generation Sequencing by Carbo, Ellen C, Russcher, Anne, Kraakman, Margriet E M, de Brouwer, Caroline S, Sidorov, Igor A, Feltkamp, Mariet C W, Kroes, Aloys C M, Claas, Eric C J, de Vries, Jutte J C

“…Immunocompromised patients are prone to reactivations and (re-)infections of multiple DNA viruses. Viral load monitoring by single-target quantitative PCRs…”
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The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 by Gorbalenya, Alexander E, Baker, Susan C, Baric, Ralph S, de Groot Raoul J, Drosten, Christian, Gulyaeva, Anastasia A, Haagmans, Bart L, Lauber, Chris, Leontovich, Andrey M, Neuman, Benjamin W, Penzar Dmitry, Perlman, Stanley, Poon Leo L M, Samborskiy, Dmitry V, Sidorov, Igor A, Sola, Isabel, Ziebuhr, John

“…The present outbreak of a coronavirus-associated acute respiratory disease called coronavirus disease 19 (COVID-19) is the third documented spillover of an…”
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Broadly Cross-Reactive HIV-1-Neutralizing Human Monoclonal Fab Selected for Binding to gp120-CD4-CCR5 Complexes by Moulard, Maxime, Phogat, Sanjay K., Shu, Yuuei, Labrijn, Aran F., Xiao, Xiaodong, Binley, James M., Zhang, Mei-Yun, Sidorov, Igor A., Broder, Christopher C., Robinson, James, Paul W. H. I. Parren, Burton, Dennis R., Dimitrov, Dimiter S.

“…HIV-1 entry into cells involves formation of a complex between gp120 of the viral envelope glycoprotein (Env), a receptor (CD4), and a coreceptor, typically…”
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Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses by Lehmann, Kathleen C, Gulyaeva, Anastasia, Zevenhoven-Dobbe, Jessika C, Janssen, George M C, Ruben, Mark, Overkleeft, Hermen S, van Veelen, Peter A, Samborskiy, Dmitry V, Kravchenko, Alexander A, Leontovich, Andrey M, Sidorov, Igor A, Snijder, Eric J, Posthuma, Clara C, Gorbalenya, Alexander E

“…RNA viruses encode an RNA-dependent RNA polymerase (RdRp) that catalyzes the synthesis of their RNA(s). In the case of positive-stranded RNA viruses belonging…”
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Portable microwave radiometer for wearable devices by Vesnin, Sergey G., Sedankin, Mikhail K., Ovchinnikov, Lev M., Gudkov, Alexander G., Leushin, Vitaly Yu, Sidorov, Igor A., Goryanin, Igor I.

“…[Display omitted] •Wearable microwave radiometer can monitor the core body temperature continuously 24/7.•The size of stable wearable microwave radiometer is…”
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Naïve T-Cell Dynamics in Human Immunodeficiency Virus Type 1 Infection: Effects of Highly Active Antiretroviral Therapy Provide Insights into the Mechanisms of Naïve T-Cell Depletion by DI MASCIO, Michele, SERETI, Irini, SIDOROV, Igor A, DIMITROV, Dimiter S, POLIS, Michael A, KOVACS, Joseph A, MATTHEWS, Lynn T, NATARAJAN, Ven, ADELSBERGER, Joseph, LEMPICKI, Richard, YODER, Christian, JONES, Elizabeth, CHOW, Catherine, METCALF, Julia A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Torque teno virus loads after kidney transplantation predict allograft rejection but not viral infection by van Rijn, Aline L, Wunderink, Herman F, Sidorov, Igor A, de Brouwer, Caroline S, Kroes, Aloysius CM, Putter, Hein, de Vries, Aiko PJ, Rotmans, Joris I, Feltkamp, Mariet CW

“…•TTV loads increase substantially with immunosuppression after kidney transplantation.•With every 10-fold TTV load-increase the risk of organ rejection…”
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Identification and Characterization of a New Cross-Reactive Human Immunodeficiency Virus Type 1-Neutralizing Human Monoclonal Antibody by ZHANG, Mei-Yun, XIAODONG XIAO, BRODER, Christopher C, BURTON, Dennis R, QUINNAN, Gerald V, DIMITROV, Dimiter S, SIDOROV, Igor A, CHOUDHRY, Vidita, CHAM, Fatim, PENG FEI ZHANG, BOUMA, Peter, ZWICK, Michael, CHOUDHARY, Anil, MONTEFIORI, David C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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SNAD: Sequence Name Annotation-based Designer by Sidorov, Igor A, Reshetov, Denis A, Gorbalenya, Alexander E

“…A growing diversity of biological data is tagged with unique identifiers (UIDs) associated with polynucleotides and proteins to ensure efficient…”
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Characterization of SARS-CoV-2 replication in human H1299/ACE2 cells: A versatile and practical infection model for antiviral research and beyond by Salgado-Benvindo, Clarisse, Tas, Ali, Zevenhoven-Dobbe, Jessika C., van der Meer, Yvonne, Sidorov, Igor A., Leijs, Anouk A., Wanningen, Patrick, Gelderloos, Anne T., van Kasteren, Puck B., Snijder, Eric J., van Hemert, Martijn J.

“…A range of cell culture infection models have been used to study SARS-CoV-2 and perform antiviral drug research. Commonly used African green monkey Vero, human…”
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Coronavirus discovery by metagenomic sequencing: a tool for pandemic preparedness by Carbo, Ellen C., Sidorov, Igor A., Zevenhoven-Dobbe, Jessika C., Snijder, Eric J., Claas, Eric C., Laros, Jeroen F.J., Kroes, Aloys C.M., de Vries, Jutte J.C.

“…The SARS-CoV-2 pandemic of 2020 is a prime example of the omnipresent threat of emerging viruses that can infect humans. A protocol for the identification of…”
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Improved diagnosis of viral encephalitis in adult and pediatric hematological patients using viral metagenomics by Carbo, Ellen C., Buddingh, Emilie P., Karelioti, Evita, Sidorov, Igor A., Feltkamp, Mariet C.W., Borne, Peter A. von dem, Verschuuren, Jan J.G.M., Kroes, Aloys C.M., Claas, Eric C.J., de Vries, Jutte J.C.

“…•A metagenomics protocol employing virus capture probes was validated and retrospectively applied to 41 hematological adult and pediatric patients presenting…”
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Benchmark of thirteen bioinformatic pipelines for metagenomic virus diagnostics using datasets from clinical samples by de Vries, Jutte J.C., Brown, Julianne R., Fischer, Nicole, Sidorov, Igor A., Morfopoulou, Sofia, Huang, Jiabin, Munnink, Bas B. Oude, Sayiner, Arzu, Bulgurcu, Alihan, Rodriguez, Christophe, Gricourt, Guillaume, Keyaerts, Els, Beller, Leen, Bachofen, Claudia, Kubacki, Jakub, Cordey, Samuel, Laubscher, Florian, Schmitz, Dennis, Beer, Martin, Hoeper, Dirk, Huber, Michael, Kufner, Verena, Zaheri, Maryam, Lebrand, Aitana, Papa, Anna, van Boheemen, Sander, Kroes, Aloys C.M., Breuer, Judith, Lopez-Labrador, F. Xavier, Claas, Eric C.J.

“…Metagenomic sequencing is increasingly being used in clinical settings for difficult to diagnose cases. The performance of viral metagenomic protocols relies…”
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Possibilities of increasing the interference immunity of radiothermograph applicator antennas for brain diagnostics by Leushin, Vitaly Yu, Gudkov, Alexander G., Porokhov, Igor O., Vesnin, Sergey G., Sedankin, Mikhail K., Sidorov, Igor A., Solov’ev, Yuriy V., Agasieva, Svetlana V., Chizhikov, Sergey V.

“…The problems of interference immunity of medical radiothermographs are discussed. The possibility of increasing the interference immunity of radiothermographs…”
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Multicenter benchmarking of short and long read wet lab protocols for clinical viral metagenomics by Lopez-Labrador, F. Xavier, Huber, Michael, Sidorov, Igor A., Brown, Julianne R., Cuypers, Lize, Laenen, Lies, Vanmechelen, Bert, Maes, Piet, Fischer, Nicole, Pichler, Ian, Storey, Nathaniel, Atkinson, Laura, Schmutz, Stefan, Kufner, Verena, van Boheemen, Sander, Mulders, Claudia E., Grundhoff, Adam, Blümke, Patrick, Robitaille, Alexis, Cinek, Ondrej, Hubáčková, Klára, Mourik, Kees, Boers, Stefan A., Stauber, Lea, Salmona, Maud, Cappy, Pierre, Ramette, Alban, Franze’, Alessandra, LeGoff, Jerome, Claas, Eric C.J., Rodriguez, Christophe, de Vries, Jutte J.C.

“…Metagenomics is gradually being implemented for diagnosing infectious diseases. However, in-depth protocol comparisons for viral detection have been limited to…”
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