Search Results - "SIBSON, Ross"

Expression and splicing of the unfolded protein response gene XBP‐1 are significantly associated with clinical outcome of endocrine‐treated breast cancer by Davies, Michael P.A., Barraclough, Dong Liu, Stewart, Ceri, Joyce, Kathryn A., Eccles, Richard M., Barraclough, Roger, Rudland, Philip S., Sibson, David Ross

“…X‐box binding protein 1 (XBP‐1) is stimulated by endoplasmic reticulum stress as part of the unfolded protein response (UPR), which can promote apoptosis or…”
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Association of oestrogen receptor beta 2 (ER beta 2/ER beta cx) with outcome of adjuvant endocrine treatment for primary breast cancer--a retrospective study by Vinayagam, Raman, Sibson, D Ross, Holcombe, Christopher, Aachi, Vijay, Davies, Michael Pa

“…Oestrogen receptor beta (ERbeta) modulates ERalpha activity; wild type ERbeta (ERbeta1) and its splice variants may therefore impact on hormone responsiveness…”
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Microarray analysis of suppression subtracted hybridisation libraries identifies genes associated with breast cancer progression by Barraclough, Dong Liu, Sewart, Susan, Rudland, Philip S, Shoker, Balvinder S, Sibson, D Ross, Barraclough, Roger, Davies, Michael P A

“…A major challenge of cancer research is to identify key molecules which are responsible for the development of the malignant metastatic phenotype, the major…”
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Human homologue of cement gland protein, a novel metastasis inducer associated with breast carcinomas by DONG LIU, RUDLAND, Philip S, SIBSON, D. Ross, PLATT-HIGGINS, Angela, BARRACLOUGH, Roger

“…A suppression subtractive cDNA library representing mRNAs expressed at a higher level in the malignant human breast cancer cell line, MCF-7, relative to a…”
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Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas by Davies, Michael P A, O'Neill, Penny A, Innes, Helen, Sibson, D Ross

“…Genetic abnormalities or mutations in premalignant breast lesions may have a role in progression toward malignancy or influence the behaviour of subsequent…”
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Gene expression profiling in bladder cancer identifies potential therapeutic targets by Hussain, Syed A, Palmer, Daniel H, Syn, Wing-Kin, Sacco, Joseph J, Greensmith, Richard M D, Elmetwali, Taha, Aachi, Vijay, Lloyd, Bryony H, Jithesh, Puthen V, Arrand, John, Barton, Darren, Ansari, Jawaher, Sibson, D Ross, James, Nicholas D

“…Despite advances in management, bladder cancer remains a major cause of cancer related complications. Characterisation of gene expression patterns in bladder…”
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Gene expression in oligodendroglial tumors by Shaw, Elisabeth J, Haylock, Brian, Husband, David, du Plessis, Daniel, Sibson, D Ross, Warnke, Peter C, Walker, Carol

“…BACKGROUNDOligodendroglial tumors with 1p/19q loss are more likely to be chemosensitive and have longer survival than those with intact 1p/19q, but not all…”
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Gene expression in oligodendroglial tumors by Shaw, Elisabeth J., Haylock, Brian, Husband, David, du Plessis, Daniel, Sibson, D. Ross, Warnke, Peter C., Walker, Carol

“…Background Oligodendroglial tumors with 1p/19q loss are more likely to be chemosensitive and have longer survival than those with intact 1p/19q, but not all…”
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Invasion of low passage oral carcinoma cells in organotypic models is influenced by the source of both the cancer and cancer-associated fibroblast cells by Dhanda, Jag, Stanbury, John, Triantafyllou, Asterios, Acha-Sagredo, Amelia, Wilson, James, Woolgar, Julia, Sibson, Ross, Shaw, Richard, Risk, Janet

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Molecular indexing of human genomic DNA by Sibson, D R, Gibbs, F E

“…Molecular indexing sorts DNA fragments into subsets for inter-sample comparisons. Type IIS or interrupted palindrome restriction endonucleases, which result in…”
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Subgroups of non-atypical hyperplasia of breast defined by proliferation of oestrogen receptor-positive cells by Iqbal, Mussawar, Davies, Michael P. A., Shoker, Balvinder S., Jarvis, Christine, Ross Sibson, D., Sloane, John P.

“…In normal breast, there is a negative association between expression of oestrogen receptor (ER) and the proliferation marker Ki67, indicating that ER‐positive…”
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Declining estrogen receptor-β expression defines malignant progression of human breast neoplasia by SHAABAN, Abeer M, O'NEILL, Penny A, DAVIES, Michael P. A, SIBSON, Ross, WEST, Christopher R, SMITH, Paul H, FOSTER, Christopher S

“…It has been shown that the risk of breast cancer developing in certain morphologically identifiable benign breast lesions correlates with expression of…”
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Gene expression in oligodendroglial tumors by Shaw, Elisabeth J, Haylock, Brian, Husband, David, du Plessis, Daniel, Sibson, D Ross, Warnke, Peter C, Walker, Carol

“…Oligodendroglial tumors with 1p/19q loss are more likely to be chemosensitive and have longer survival than those with intact 1p/19q, but not all respond to…”
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Molecular and genetic abnormalities in radial scar by Iqbal, Mussawar, Shoker, Balvinder S., Foster, Christopher S., Jarvis, Christine, Sibson, D.Ross, Davies, Michael P.A.

“…Hyperplasia of usual type (HUT) may be an early precursor of breast carcinoma and has been shown to contain molecular and genetic abnormalities previously seen…”
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Examination of tumour histopathology and gene expression in a neu/S100A4 transgenic model of metastatic breast cancer by Simpson, Peter T., Shoker, Balvinder S., Barraclough, Roger, Halliwell, Nigel, Rudland, Philip S., Sibson, D. Ross, Davies, Michael P. A.

“…Elevated levels of the calcium‐binding protein S100A4 have been causally linked to the metastatic spread of breast cancer cells in several in vitro and in vivo…”
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NOTCH1 mutations and extracapsular spread in oral squamous cell carcinoma lymph node metastasis by Bhattacharya, Priyanka, Risk, Janet, Dhanda, Jagjit, Shaw, Richard, Lloyd, Bryony, Sibson, David Ross

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Novel polymerase chain reaction approach for full-coding p53 mutation detection in microdissected archival tumors by Thompson-Hehir, J, Davies, M P, Green, J A, Halliwell, N, Joyce, K A, Salisbury, J, Sibson, D R, Vergote, I, Walker, C

“…Evidence suggests that up to 25% of p53 mutations are outside of exons 5-8 and that insertions, deletions, and polymorphic sites in the p53 gene may play a…”
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Variant estrogen receptor α mRNAs in human breast cancer specimens by Anandappa, Shanez Y., Sibson, Ross, Platt‐Higgins, Angela, Winstanley, John H.R., Rudland, Philip S., Barraclough, Roger

“…A panel of human breast cancer specimens was examined for single base change mutations by DNA sequencing and for larger deletions using a PCR‐based assay. In…”
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The occurrence of deletions and point mutations in the estrogen receptor gene in breast cancer specimens by Winstanley, John H.R., Irwin, Shanez, Barraclough, Roger, Sibson, Ross

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Estrogen Receptor-Positive Proliferating Cells in the Normal and Precancerous Breast by Shoker, Balvinder S., Jarvis, Christine, Clarke, Robert B., Anderson, Elizabeth, Hewlett, Joanne, Davies, Michael P.A., Sibson, D. Ross, Sloane, John P.

“…Recently it has been shown that epithelial cell expression of the estrogen receptor (ER) and that of the proliferation-associated marker Ki-67 are almost…”
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