Search Results - "SIBER, George R"

Evidence for antibody as a protective correlate for COVID-19 vaccines by Earle, Kristen A., Ambrosino, Donna M., Fiore-Gartland, Andrew, Goldblatt, David, Gilbert, Peter B., Siber, George R., Dull, Peter, Plotkin, Stanley A.

“…A correlate of protection (CoP) is urgently needed to expedite development of additional COVID-19 vaccines to meet unprecedented global demand. To assess…”
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How Can Vaccines Contribute to Solving the Antimicrobial Resistance Problem? by Lipsitch, Marc, Siber, George R

“…There is a growing appreciation for the role of vaccines in confronting the problem of antimicrobial resistance (AMR). Vaccines can reduce the prevalence of…”
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Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies by Siber, George R, Chang, Ih, Baker, Sherryl, Fernsten, Philip, O’Brien, Katherine L, Santosham, Mathuram, Klugman, Keith P, Madhi, Shabir A, Paradiso, Peter, Kohberger, Robert

“…Abstract Estimates of minimum protective antibody concentrations for vaccine preventable diseases are of critical importance in assessing whether new vaccines…”
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Serum Serotype-Specific Pneumococcal Anticapsular Immunoglobulin G Concentrations after Immunization with a 9-Valent Conjugate Pneumococcal Vaccine Correlate with Nasopharyngeal Acquisition of Pneumococcus by Dagan, Ron, Givon-Lavi, Noga, Fraser, Drora, Lipsitch, Marc, Siber, George R., Kohberger, Robert

“…BackgroundImmunization with pneumococcal conjugate vaccines (PCVs) reduces nasopharyngeal colonization by Streptococcus pneumoniae. We attempted to correlate…”
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Identification of novel virus-specific antigens by CD4+ and CD8+ T cells from asymptomatic HSV-2 seropositive and seronegative donors by Long, Deborah, Skoberne, Mojca, Gierahn, Todd M, Larson, Shane, Price, Jessica A, Clemens, Veronica, Baccari, Amy E, Cohane, Kenya P, Garvie, Danielle, Siber, George R, Flechtner, Jessica B

“…Abstract Reactivation of latent herpes simplex virus 2 (HSV-2) infections can be characterized by episodic recurrent genital lesions and/or viral shedding. We…”
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Resolution of Chlamydia trachomatis Infection Is Associated with a Distinct T Cell Response Profile by Picard, Michele D, Bodmer, Jean-Luc, Gierahn, Todd M, Lee, Alexander, Price, Jessica, Cohane, Kenya, Clemens, Veronica, DeVault, Victoria L, Gurok, Galina, Kohberger, Robert, Higgins, Darren E, Siber, George R, Flechtner, Jessica Baker, Geisler, William M

“…Chlamydia trachomatis is the causative agent of the most frequently reported bacterial sexually transmitted infection, the total burden of which is…”
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Phase 1 trial of a 13-valent pneumococcal conjugate vaccine in healthy adults by Scott, Daniel A, Komjathy, Steven F, Hu, Branda T, Baker, Sherryl, Supan, Lois A, Monahan, Carol A, Gruber, William, Siber, George R, Lockhart, Stephen P

“…Abstract In a Phase 1 study, 15 healthy subjects were randomized to receive a 13-valent pneumococcal conjugate vaccine (PCV13) and 15 to receive a 23-valent…”
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Treatment of severe pertussis: a study of the safety and pharmacology of intravenous pertussis immunoglobulin by BRUSS, JON B, MALLEY, RICHARD, HALPERIN, SCOTT, DOBSON, SIMON, DHALLA, MOHSIN, MCIVER, JAMES, SIBER, GEORGE R

“…BACKGROUND.Pertussis in infants is often severe, resulting in complications and prolonged hospitalization. Treatment is limited to supportive care. Antibiotics…”
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Quantitative Priming with Inactivated Pertussis Toxoid Vaccine in the Aerosol Challenge Model by BRUSS, Jon B, SIBER, George R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Normal IgG and Impaired IgM Responses to Polysaccharide Vaccines in Asplenic Patients by Molrine, Deborah C., Siber, George R., Samra, Yecheskel, Shevy, Drora Samra, MacDonald, Kristin, Cieri, Rocco, Ambrosino, Donna M.

“…Asplenic patients are at increased risk for life-threatening infections with polysaccharide-encapsulated organisms, and reports of responses to polysaccharide…”
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Pneumococcal Disease: Prospects for a New Generation of Vaccines by Siber, George R.

“…Abstract only…”
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Placental and breast transfer of antibodies after maternal immunization with polysaccharide meningococcal vaccine: a randomized, controlled evaluation by Shahid, Nigar S., Steinhoff, Mark C., Roy, Eliza, Begum, Tahmina, Thompson, Claudette M., Siber, George R.

“…We evaluated the strategy of maternal immunization with Neisseria meningitidis (Nm) vaccine in Asian mothers, to assess potential protection of infants,…”
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Evaluation of a Guinea Pig Model to Assess Interference in the Immunogenicity of Different Components of a Combination Vaccine Comprising Diphtheria, Tetanus and Acellular Pertussis (DTaP) Vaccine and Haemophilus influenzae type b Capsular Polysaccharide Conjugate Vaccine by Gupta, Rajesh K., Anderson, Roger, Cecchini, Douglas, Rost, Bradford, Xu, Jin, Gendreau, Katherine, Saroff, Denise L, Marchant, Colin, Siber, George R

“…A guinea pig model to assess the immunogenicity of a combination vaccine containing diphtheria, tetanus and acellular pertussis (DTaP) vaccine and Haemophilus…”
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Correlation between serum IgG-2 concentrations and the antibody response to bacterial polysaccharide antigens by Siber, G R, Schur, P H, Aisenberg, A C, Weitzman, S A, Schiffman, G

“…We measured serum concentrations of immunoglobulin classes and IgG subclasses in 53 patients who had completed treatment for Hodgkin's disease and in 10…”
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Contributions of Native Americans to the global control of infectious diseases by Santosham, Mathuram, Reid, Raymond, Chandran, Aruna, Millar, Eugene V, Watt, James P, Weatherholtz, Robert, Donaldson, Connie, Croll, Janné, Moulton, Lawrence H, Thompson, Claudette M, Siber, George R, O’Brien, Katherine L

“…Abstract For over a half of a century, Native American populations have participated in numerous studies regarding the epidemiology, prevention and treatment…”
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Formation and cell-medium partitioning of autoinhibitory free fatty acids and cyclodextrin's effect in the cultivation of Bordetella pertussis by Fröhlich, Bert T, d'Alarcao, Marc, Feldberg, Ross S, Nicholson, Mary L, Siber, George R, Swartz, Randall W

“…Palmitic, palmitoleic and stearic acids were found in the extracted cellular lipids of virulent Bordetella pertussis as unesterified acids in confirmation of…”
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Stabilization of Tetanus and Diphtheria Toxoids Against Moisture-Induced Aggregation by Schwendeman, Steven P., Costantino, Henry R., Gupta, Rajesh K., Siber, George R., Klibanov, Alexander M., Langer, Robert

“…The progress toward single-dose vaccines has been limited by the poor solid-state stability of vaccine antigens within controlled-release polymers, such as…”
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Safety and antibody persistence following Haemophilus influenzae type b conjugate or pneumococcal polysaccharide vaccines given before pregnancy in women of childbearing age and their infants by Santosham, Mathuram, Englund, Janet A, McInnes, Pamela, Croll, Janne, Thompson, Claudette M, Croll, Larry, Glezen, W Paul, Siber, George R

“…BACKGROUND.Immunization of healthy women before pregnancy is a potential approach to providing increased levels of maternal antibody to newborns to protect…”
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Impaired antibody response to pneumococcal vaccine after treatment for Hodgkin's disease by Siber, G R, Weitzman, S A, Aisenberg, A C, Weinstein, H J, Schiffman, G

“…To determine if a normal antibody response can develop after therapy for Hodgkin's disease, we immunized 53 patients and 10 normal controls with dodecavalent…”
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Development of a pneumococcal conjugate vaccine by Siber, George R

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