Search Results - "SIBEKO, Sengeziwe"

Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women by Abdool Karim, Quarraisha, Abdool Karim, Salim S, Frohlich, Janet A, Grobler, Anneke C, Baxter, Cheryl, Mansoor, Leila E, Kharsany, Ayesha B.M, Sibeko, Sengeziwe, Mlisana, Koleka P, Omar, Zaheen, Gengiah, Tanuja N, Maarschalk, Silvia, Arulappan, Natasha, Mlotshwa, Mukelisiwe, Morris, Lynn, Taylor, Douglas

“…The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed the effectiveness and safety of a 1% vaginal gel formulation of…”
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Preventing HIV Infection in Women: A global Health Imperative by Karim, Quarraisha Abdool, Sibeko, Sengeziwe, Baxter, Cheryl

“…Women account for approximately one-half of all human immunodeficiency virus (HIV) infections worldwide. Sexual transmission is the dominant mode of HIV…”
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The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4+ T Cell Decline and High Viral Load during Acute Infection by GRAY, Elin S, MADIGA, Maphuti C, ABDOOL KARIM, Salim S, MORRIS, Lynn, HERMANUS, Tandile, MOORE, Penny L, WIBMER, Constantinos Kurt, TUMBA, Nancy L, WERNER, Lise, MLISANA, Koleka, SIBEKO, Sengeziwe, WILLIAMSON, Carolyn

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Role of the epithelium in human papillomavirus and human immunodeficiency virus infections in the female genital tract by Sibeko, Sengeziwe, Sanderson, Micheline, Moyo, Sizulu, Botha, Matthys H

“…Two-thirds of people living with human immunodeficiency virus type 1 (HIV-1) infection reside in Sub-Saharan Africa, where there are the highest prevalence and…”
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Potent and Broad Neutralization of HIV-1 Subtype C by Plasma Antibodies Targeting a Quaternary Epitope Including Residues in the V2 Loop by MOORE, Penny L, GRAY, Elin S, SIBEKO, Sengeziwe, MLISANA, Koleka, ABDOOL KARIM, Salim S, WILLIAMSON, Carolyn, PINTER, Abraham, MORRIS, Lynn, SHEWARD, Daniel, MADIGA, Maphuti, RANCHOBE, Nthabeleng, ZHONG LAI, HONNEN, William J, NONYANE, Molati, TUMBA, Nancy, HERMANUS, Tandile

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The Development of CD4 Binding Site Antibodies during HIV-1 Infection by LYNCH, Rebecca M, TRAN, Lillian, MONTEFIORI, David C, SIBEKO, Sengeziwe, SODERBERG, Kelly, TOMARAS, Georgia, YANG, Zhi-Yong, NABEL, Gary J, SCHUITEMAKER, Hanneke, MORRIS, Lynn, HAYNES, Barton F, MASCOLA, John R, LOUDER, Mark K, SCHMIDT, Stephen D, COHEN, Myron, DERSIMONIAN, Rebecca, EULER, Zelda, GRAY, Elin S, ABDOOL KARIM, Salim, KIRCHHERR, Jennifer

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Women with pregnancies had lower adherence to 1% tenofovir vaginal gel as HIV preexposure prophylaxis in CAPRISA 004, a phase IIB randomized-controlled trial by Matthews, Lynn T, Sibeko, Sengeziwe, Mansoor, Leila E, Yende-Zuma, Nonhlanhla, Bangsberg, David R, Karim, Quarraisha Abdool

“…Antiretroviral prophylaxis may be a critical strategy to reduce periconception HIV transmission. Maximizing the benefit of periconception pharmacologic HIV…”
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Recruitment of high risk women for HIV prevention trials: baseline HIV prevalence and sexual behavior in the CAPRISA 004 tenofovir gel trial by Karim, Quarraisha Abdool, Kharsany, Ayesha Bm, Frohlich, Janet A, Baxter, Cheryl, Yende, Nonhlanhla, Mansoor, Leila E, Mlisana, Koleka P, Maarschalk, Silvia, Arulappan, Natasha, Grobler, Anneke, Sibeko, Sengeziwe, Omar, Zaheen, Gengiah, Tanuja N, Mlotshwa, Mukelisiwe, Samsunder, Natasha, Karim, Salim S Abdool

“…Young women in sub-Saharan Africa bear a disproportionate burden of HIV infection compared to men but have limited options to reduce their HIV risk…”
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Contraception and pregnancy in microbicide trials by Sibeko, Sengeziwe, MB ChB, FCOG, MS, Cohen, Gabriel M., BA, Moodley, Jagidesa, MB ChB, FRCOG, MD

“…The distinctive feature of the human immunodeficiency virus (HIV) epidemic in Sub-Saharan Africa is the burden on women, in particular young women of…”
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Recent Advances and New Challenges in Cisgender Women’s Gynecologic and Obstetric Health in the Context of HIV by DEESE, JENNIFER, HEFFRON, RENEE, JASPAN, HEATHER, MASSON, LINDI, SMIT, JENNIFER A., SIBEKO, SENGEZIWE

“…Although rates of human immunodeficiency virus (HIV) have declined globally over the past 10 years, United Nations Programme on HIV/AIDS estimates 1.7 million…”
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Innate Immune Activation Enhances HIV Acquisition in Women, Diminishing the Effectiveness of Tenofovir Microbicide Gel by Naranbhai, Vivek, Karim, Salim S. Abdool, Altfeld, Marcus, Samsunder, Natasha, Durgiah, Raveshni, Sibeko, Sengeziwe, Karim, Quarraisha Abdool, Carr, William H.

“…The antiretroviral agent, tenofovir, formulated as a vaginal microbicide gel, reduces human immunodeficiency virus (HIV) acquisition by 39% in women. This…”
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Recent advances and new challenges in cisgender women’s gynaecological and obstetric health in the context of HIV by Deese, Jennifer, Heffron, Renee, Jaspan, Heather, Masson, Lindi, Smit, Jennifer A, Sibeko, Sengeziwe

“…Although rates of HIV have declined globally over the past ten years, UNAIDS estimates 1.7 million new infections occurred in 2019, with cisgender women and…”
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How can we design better vaccines to prevent HIV infection in women? by Rafferty, Hannah, Sibeko, Sengeziwe, Rowland-Jones, Sarah

“…The human immunodeficiency virus (HIV) burden in women continues to increase, and heterosexual contact is now the most common route of infection worldwide…”
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Cover by Makinde, Julia, Jones, Clifford, Bartolf, Angela, Sibeko, Sengeziwe, Baden, Susan, Cosgrove, Catherine, Shattock, Robin J.

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Localized cyclical variations in immunoproteins in the female genital tract and the implications on the design and assessment of mucosal infection and therapies by Makinde, Julia, Jones, Clifford, Bartolf, Angela, Sibeko, Sengeziwe, Baden, Susan, Cosgrove, Catherine, Shattock, Robin J.

“…Problem Fluctuating hormones regulate reproductive processes in the female genital tract. Consequent changes in the local immunological environment are likely…”
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Lower concentrations of chemotactic cytokines and soluble innate factors in the lower female genital tract associated with the use of injectable hormonal contraceptive by Ngcapu, Sinaye, Masson, Lindi, Sibeko, Sengeziwe, Werner, Lise, McKinnon, Lyle R, Mlisana, Koleka, Shey, Muki, Samsunder, Natasha, Karim, Salim Abdool, Karim, Quarraisha Abdool, Passmore, Jo-Ann S

“…Highlights • Injectable hormonal contraceptives (HCs) may regulate genital tract innate immunity. • Genital tract cytokines were suppressed in women using…”
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From the Laboratory to Clinical Trials and Back Again: Lessons Learned from HIV Prevention Trials by Sibeko, Sengeziwe, Makvandi-Nejad, Shokouh

“…Problem Inadequate, irrelevant, or inappropriate timing of biological specimen collection during clinical trials is a cause for delay in understanding and…”
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Contraceptive Choices, Pregnancy Rates, and Outcomes in a Microbicide Trial by SIBEKO, Sengeziwe, BAXTER, Cheryl, YENDE, Nonhlanhla, QUARRAISHA ABDOOL KARIM, ABDOOL KARIM, Salim S

“…Women who become pregnant during the conduct of biomedical human immunodeficiency virus prevention trials are taken off the study product for safety reasons…”
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The Impact of Macrophage Inflammatory Protein-3 Alpha and Other Innate Immune Markers on Susceptibility/Resistance to Hiv Infection in the Female Genital Tract Mucosa Using Cellular and Ex Vivo Tissue Models by Sibeko, Sengeziwe

“…The distinctive feature of the Human Immunodeficiency Virus (HIV) epidemic in the 21st century is the burden it places on women. Scientists believe that the…”
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Preventing HIV Infection in Women: A Global Health Imperative: Synergistic Pandemics: Confronting the Global HIV and Tuberculosis Epidemics by KARIM, Quarraisha Abdool, SIBEKO, Sengeziwe, BAXTER, Cheryl

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