Search Results - "SIAN, J"

Iron as the concert master in the pathogenic orchestra playing in sporadic Parkinson’s disease by Riederer, P., Monoranu, C., Strobel, S., Iordache, T., Sian-Hülsmann, J.

“…About 60 years ago, the discovery of a deficiency of dopamine in the nigro-striatal system led to a variety of symptomatic therapeutic strategies to supplement…”
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Water sensitive communities: a systematic review with a complex adaptive systems perspective by Chadfield, Sian J., Wei, Yongping, Lieske, Scott N.

“…There have been increasing calls for a paradigm shift in urban water management to a water sensitive cities (WSC) approach. Although it is well recognised that…”
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Lateralisation in Parkinson disease by Riederer, P., Jellinger, K. A., Kolber, P., Hipp, G., Sian-Hülsmann, J., Krüger, R.

“…Asymmetry of dopaminergic neurodegeneration and subsequent lateralisation of motor symptoms are distinctive features of Parkinson’s disease compared to other…”
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Advanced Modulation Schemes for Short-Range Optical Communications by Randel, Sebastian, Breyer, Florian, Lee, Sian C J, Walewski, Joachim W

“…The performance of advanced modulation schemes for spectrally efficient data transmission is reviewed, targeting short-range intensity-modulated optical…”
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The Microbiome in Posttraumatic Stress Disorder and Trauma-Exposed Controls: An Exploratory Study by Hemmings, Sian M J, Malan-Müller, Stefanie, van den Heuvel, Leigh L, Demmitt, Brittany A, Stanislawski, Maggie A, Smith, David G, Bohr, Adam D, Stamper, Christopher E, Hyde, Embriette R, Morton, James T, Marotz, Clarisse A, Siebler, Philip H, Braspenning, Maarten, Van Criekinge, Wim, Hoisington, Andrew J, Brenner, Lisa A, Postolache, Teodor T, McQueen, Matthew B, Krauter, Kenneth S, Knight, Rob, Seedat, Soraya, Lowry, Christopher A

“…Inadequate immunoregulation and elevated inflammation may be risk factors for posttraumatic stress disorder (PTSD), and microbial inputs are important…”
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The significance of neuronal lateralisation in Parkinson’s disease by Riederer, P., Sian-Hülsmann, J.

“…The destruction of the dopaminergic neurons in the substantia nigra (SN) and consequent depletion of striatal dopamine elicits the main movement deficits…”
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Associations between telomere length and symptoms of posttraumatic stress disorder and appetitive aggression in trauma-exposed men by Womersley, Jacqueline S., Xulu, Khethelo R., Sommer, Jessica, Hinsberger, Martina, Kidd, Martin, Elbert, Thomas, Weierstall, Roland, Kaminer, Debbie, Malan-Müller, Stefanie, Seedat, Soraya, M. J. Hemmings, Sian

“…•Appetitive aggression and PTSD are associated with exposure to community violence.•There is a paucity of data on the neurobiology of appetitive…”
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Short-read full-length 16S rRNA amplicon sequencing for characterisation of the respiratory bacteriome of captive and free-ranging African elephants (Loxodonta africana) by Martin, Lauren C., O’Hare, Michaela A., Ghielmetti, Giovanni, Twesigomwe, David, Kerr, Tanya J., Gumbo, Rachiel, Buss, Peter E., Kitchin, Natasha, Hemmings, Sian M. J., Miller, Michele A., Goosen, Wynand J.

“…Hypervariable region sequencing of the 16S ribosomal RNA (rRNA) gene plays a critical role in microbial ecology by offering insights into bacterial communities…”
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Rates of and factors associated with atopy and allergies in posttraumatic stress disorder as compared to controls by Ryklief, Zulfa, Suliman, Sharain, Hemmings, Sian M.J., van den Heuvel, Leigh L., Seedat, Soraya

“…Several studies suggest a relationship between atopy and psychiatric disorders, but few have investigated the association between atopic conditions and…”
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FKBP5 intron 7 methylation is associated with higher anxiety proneness and smaller right thalamus volume in adolescents by Womersley, Jacqueline S., Roeh, Simone, Martin, Lindi, Ahmed-Leitao, Fatima, Sauer, Susann, Rex-Haffner, Monika, Hemmings, Sian M. J., Binder, Elisabeth B., Seedat, Soraya

“…Dysregulation of stress response systems may mediate the detrimental effects of childhood trauma (CT) on mental health. FKBP5 regulates glucocorticoid receptor…”
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UCN2: a new candidate influencing pancreatic β-cell adaptations in pregnancy by Simpson, Sian J S, Smith, Lorna I F, Jones, Peter M, Bowe, James E

“…The corticotropin-releasing hormone (CRH) family of peptides, including urocortin (UCN) 1, 2 and 3, are established hypothalamic neuroendocrine peptides,…”
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Dissecting the genetic association of C-reactive protein with PTSD, traumatic events, and social support by Muniz Carvalho, Carolina, Wendt, Frank R, Maihofer, Adam X, Stein, Dan J, Stein, Murray B, Sumner, Jennifer A, Hemmings, Sian M J, Nievergelt, Caroline M, Koenen, Karestan C, Gelernter, Joel, Belangero, Sintia I, Polimanti, Renato

“…Inflammatory markers like C-reactive protein (CRP) have been associated with post-traumatic stress disorder (PTSD) and traumatic experiences, but the…”
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Crystal structure of the essential transcription antiterminator M2-1 protein of human respiratory syncytial virus and implications of its phosphorylation by Tanner, Sian J., Ariza, Antonio, Richard, Charles-Adrien, Kyle, Hannah F., Dods, Rachel L., Blondot, Marie-Lise, Wu, Weining, Trincão, José, Trinh, Chi H., Hiscox, Julian A., Carroll, Miles W., Silman, Nigel J., Eléouët, Jean-François, Edwards, Thomas A., Barr, John N.

“…The M2-1 protein of the important pathogen human respiratory syncytial virus is a zinc-binding transcription antiterminator that is essential for viral gene…”
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Brain-Derived Neurotrophic Factor (BDNF) protein levels in anxiety disorders: systematic review and meta-regression analysis by Suliman, Sharain, Hemmings, Sian M J, Seedat, Soraya

“…Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin that is involved in the synaptic plasticity and survival of neurons. BDNF is believed to be involved…”
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DNA methylation and psychotherapy response in trauma-exposed men with appetitive aggression by Xulu, Khethelo R., Womersley, Jacqueline S., Sommer, Jessica, Hinsberger, Martina, Elbert, Thomas, Weierstall, Roland, Kaminer, Debbie, Malan-Müller, Stefanie, Seedat, Soraya, Hemmings, Sian M.J.

“…•FORNET treatment reduces appetitive aggression and PTSD symptom scores•AUTS2 and NR4A2 methylation are inversely associated with PTSD symptom severity•TFAM…”
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Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization by Ariza, Antonio, Tanner, Sian J, Walter, Cheryl T, Dent, Kyle C, Shepherd, Dale A, Wu, Weining, Matthews, Susan V, Hiscox, Julian A, Green, Todd J, Luo, Ming, Elliott, Richard M, Fooks, Anthony R, Ashcroft, Alison E, Stonehouse, Nicola J, Ranson, Neil A, Barr, John N, Edwards, Thomas A

“…All orthobunyaviruses possess three genome segments of single-stranded negative sense RNA that are encapsidated with the virus-encoded nucleocapsid (N) protein…”
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A Genome-Wide Association Study and Polygenic Risk Score Analysis of Posttraumatic Stress Disorder and Metabolic Syndrome in a South African Population by Swart, Patricia C, van den Heuvel, Leigh L, Lewis, Cathryn M, Seedat, Soraya, Hemmings, Sian M J

“…Posttraumatic stress disorder (PTSD) is a trauma-related disorder that frequently co-occurs with metabolic syndrome (MetS). MetS is characterized by obesity,…”
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TERT rs2736100 and TERC rs16847897 genotypes moderate the association between internalizing mental disorders and accelerated telomere length attrition among HIV+ children and adolescents in Uganda by Kalungi, Allan, Kinyanda, Eugene, Womersley, Jacqueline S, Joloba, Moses L, Ssembajjwe, Wilber, Nsubuga, Rebecca N, Kaleebu, Pontiano, Levin, Jonathan, Kidd, Martin, Seedat, Soraya, Hemmings, Sian M J

“…Internalizing mental disorders (IMDs) (depression, anxiety and post-traumatic stress disorder) have been associated with accelerated telomere length (TL)…”
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The effect of childhood trauma, ApoE genotype and HIV-1 viral protein R variants on change in cognitive performance by Womersley, Jacqueline S, Clauss, Lara B, Varathan, Olivette, Engelbrecht, Susan, Hemmings, Sian M J, Seedat, Soraya, Spies, Georgina

“…Gene-environment interactions contribute to the development of HIV-associated neurocognitive disorders. We examined whether childhood trauma, apolipoprotein E…”
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Childhood maltreatment and HIV-associated neurocognitive disorders share similar pathophysiology: a potential sensitisation mechanism? by Womersley, Jacqueline S., Seedat, Soraya, Hemmings, Sian M. J.

“…HIV-associated neurocognitive disorders (HAND) are increasingly prevalent despite the use of antiretroviral therapies. Previous research suggests that…”
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