Search Results - "SIAFAKAS, N. M"

Pivotal clinical dilemmas in collagen vascular diseases associated with interstitial lung involvement by Antoniou, K. M, Margaritopoulos, G, Economidou, F, Siafakas, N. M

“…The connective tissue disorders (CTDs), also called collagen vascular diseases (CVDs), represent a heterogeneous group of immunologically mediated inflammatory…”
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small airways and distal lung compartment in asthma and COPD: a time for reappraisal by Contoli, M, Bousquet, J, Fabbri, L.M, Magnussen, H, Rabe, K.F, Siafakas, N.M, Hamid, Q, Kraft, M

“…To cite this article: Contoli M, Bousquet J, Fabbri LM, Magnussen H, Rabe KF, Siafakas NM, Hamid Q, Kraft M. The small airways and distal lung compartment in…”
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A hypothesis for the initiation of COPD by Tzortzaki, E. G, Siafakas, N. M

“…Chronic obstructive pulmonary disease (COPD) is generally thought to depend on an aberrant immune response to a noxious or infectious agent, which may cause…”
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Exhaled markers of oxidative stress in idiopathic pulmonary fibrosis by Psathakis, K., Mermigkis, D., Papatheodorou, G., Loukides, S., Panagou, P., Polychronopoulos, V., Siafakas, N. M., Bouros, D.

“…Background  Expired breath condensate (EBC) has never been used to explore the level of oxidative stress in idiopathic pulmonary fibrosis (IPF). Therefore, the…”
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The presence of Merkel cell polyomavirus is associated with deregulated expression of BRAF and Bcl‐2 genes in non‐small cell lung cancer by Lasithiotaki, I., Antoniou, K.M., Derdas, S.P., Sarchianaki, E., Symvoulakis, E.K., Psaraki, A., Spandidos, D.A., Stathopoulos, E.N., Siafakas, N.M., Sourvinos, G.

“…Polyomaviruses such as BK virus (BKV), JC virus (JCV) and Merkel cell polyomavirus (MCPyV) are typically nononcogenic, although they have been detected in a…”
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Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma by Kupczyk, M., Dahlén, B., Sterk, P. J., Nizankowska‐Mogilnicka, E., Papi, A., Bel, E. H., Chanez, P., Howarth, P. H., Holgate, S. T., Brusselle, G., Siafakas, N. M., Gjomarkaj, M., Dahlén, S.‐E.

“…Background Although asthma is characterized by variable airways obstruction, most studies of asthma phenotypes are cross‐sectional. The stability of phenotypes…”
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Exacerbations and lung function decline in COPD: New insights in current and ex-smokers by Makris, D, Moschandreas, J, Damianaki, A, Ntaoukakis, E, Siafakas, N.M, Milic Emili, J, Tzanakis, N

“…Summary Aim To investigate whether there is a significant relationship between an increased frequency of exacerbations and the rate of forced expiratory volume…”
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Near-fatal asthma phenotype in the ENFUMOSA Cohort by Romagnoli, M., Caramori, G., Braccioni, F., Ravenna, F., Barreiro, E., Siafakas, N. M., Vignola, A. M., Chanez, P., Fabbri, L. M., Papi, A.

“…Summary Background Near‐fatal asthma (NFA) is characterized by severe asthma attacks usually requiring intensive care unit admission. This phenotype of asthma…”
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Recent advances in the pathogenesis and clinical evaluation of pulmonary fibrosis by Margaritopoulos, G A, Romagnoli, M, Poletti, V, Siafakas, N M, Wells, A U, Antoniou, K M

“…Interstitial lung diseases (ILDs) are a group of heterogeneous disorders, either idiopathic or associated with injurious or inflammatory causes, in which the…”
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Optimal assessment and management of chronic obstructive pulmonary disease (COPD) by SIAFAKAS, N. M, VERMEIRE, P, REES, J, PRIDE, N. B, PAOLETTI, P, GIBSON, J, HOWARD, P, YERNAULT, J. C, DECRAMER, M, HIGENBOTTAM, T, POSTMA, D. S

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Infliximab therapy in pulmonary fibrosis associated with collagen vascular disease by ANTONIOU, K. M, MAMOULAKI, M, MALAGARI, K, KRITIKOS, H. D, BOUROS, D, SIAFAKAS, N. M, BOUMPAS, D. T

“…To study the potential effectiveness of tumor necrosis factor a (TNF-alpha) inhibitor treatment for pulmonary fibrosis associated with a collagen vascular…”
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Surgery and the respiratory muscles by Siafakas, N M, Mitrouska, I, Bouros, D, Georgopoulos, D

“…[...]hypoxia may ensue with a detrimental effect on the condition of the patient. [...]aminophylline or doxapram may be given to minimise phrenic nerve…”
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Few smokers develop COPD. Why? by SIAFAKAS, N.M., TZORTZAKI, E.G.

“…COPD is a common disease and its major risk factor, cigarette smoking, has been identified. However, only a minority of smokers develop clinically relevant…”
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Induced sputum in the investigation of airway inflammation of COPD by Tsoumakidou, M, Tzanakis, N, Siafakas, N.M

“…During the last decade, the method of sputum induction (SI) has offered the opportunity to study inflammation in patients with chronic obstructive pulmonary…”
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Microsatellite DNA instability and COPD exacerbations by Makris, D, Tzanakis, N, Damianaki, A, Ntaoukakis, E, Neofytou, E, Zervou, M, Siafakas, N. M, Tzortzaki, E. G

“…Increased frequency of microsatellite DNA instability (MSI) has been detected in the sputum of chronic obstructive pulmonary disease (COPD) patients. The aim…”
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Combined Pulmonary Fibrosis and Emphysema in Scleroderma‐Related Lung Disease Has a Major Confounding Effect on Lung Physiology and Screening for Pulmonary Hypertension by Antoniou, K. M., Margaritopoulos, G. A., Goh, N. S., Karagiannis, K., Desai, S. R., Nicholson, A. G., Siafakas, N. M., Coghlan, J. G., Denton, C. P., Hansell, D. M., Wells, A. U.

“…Objective To assess the prevalence of combined pulmonary fibrosis and emphysema (CPFE) in systemic sclerosis (SSc) patients with interstitial lung disease…”
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Intrapleural streptokinase versus urokinase in the treatment of complicated parapneumonic effusions: a prospective, double-blind study by Bouros, D, Schiza, S, Patsourakis, G, Chalkiadakis, G, Panagou, P, Siafakas, N M

“…Intrapleural administration of fibrinolytics has been shown in small numbers of patients with complicated parapneumonic effusions (CPE) and pleural empyema to…”
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Differences in microsatellite DNA level between asthma and chronic obstructive pulmonary disease by Zervou, M. I, Tzortzaki, E. G, Makris, D, Gaga, M, Zervas, E, Economidou, E, Tsoumakidou, M, Tzanakis, N, Milic-Emili, J, Siafakas, N. M

“…Previous studies have shown that microsatellite (MS) DNA instability (MSI) is detectable in sputum cells in chronic obstructive pulmonary disease (COPD) and…”
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Inflammatory cell profiles and T-lymphocyte subsets in chronic obstructive pulmonary disease and severe persistent asthma by Tsoumakidou, M., Tzanakis, N., Kyriakou, D., Chrysofakis, G., Siafakas, N. M.

“…Summary Background Severe persistent asthma (SPA) and chronic obstructive pulmonary disease (COPD) are both associated with non‐reversible airflow limitation…”
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Increased bronchoalveolar lavage fluid CD1c expressing dendritic cells in idiopathic pulmonary fibrosis by Tsoumakidou, M, Karagiannis, K P, Bouloukaki, I, Zakynthinos, S, Tzanakis, N, Siafakas, N M

“…Chronic inflammation is implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis and is associated with persistent activation of immune responses. These…”
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