Search Results - "SHUYUN RAO"
-
1
Baseline human gut microbiota profile in healthy people and standard reporting template
Published in PloS one (11-09-2019)“…A comprehensive knowledge of the types and ratios of microbes that inhabit the healthy human gut is necessary before any kind of pre-clinical or clinical study…”
Get full text
Journal Article -
2
RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance
Published in PloS one (03-10-2019)“…We have previously demonstrated that loss of the tumor suppressive activity of ribosomal protein (RP) RPL22 predisposes to development of leukemia in mouse…”
Get full text
Journal Article -
3
Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B
Published in Blood (01-11-2012)“…Ribosomal protein (RP) mutations in diseases such as 5q− syndrome both disrupt hematopoiesis and increase the risk of developing hematologic malignancy…”
Get full text
Journal Article -
4
Aldehydes alter TGF-β signaling and induce obesity and cancer
Published in Cell reports (Cambridge) (24-09-2024)“…Obesity and fatty liver diseases—metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis…”
Get full text
Journal Article -
5
Control of Hematopoietic Stem Cell Emergence by Antagonistic Functions of Ribosomal Protein Paralogs
Published in Developmental cell (25-02-2013)“…It remains controversial whether the highly homologous ribosomal protein (RP) paralogs found in lower eukaryotes have distinct functions and this has not been…”
Get full text
Journal Article -
6
The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1
Published in PLoS genetics (01-08-2013)“…Most yeast ribosomal protein genes are duplicated and their characterization has led to hypotheses regarding the existence of specialized ribosomes with…”
Get full text
Journal Article -
7
Isolation of Nuclei from Human Snap-frozen Liver Tissue for Single-nucleus RNA Sequencing
Published in Bio-protocol (05-02-2023)“…Single-nucleus RNA sequencing (snRNA-seq) provides a powerful tool for studying cell type composition in heterogenous tissues. The liver is a vital organ…”
Get full text
Journal Article -
8
Novel Interaction between the Co-chaperone Cdc37 and Rho GTPase Exchange Factor Vav3 Promotes Androgen Receptor Activity and Prostate Cancer Growth
Published in The Journal of biological chemistry (22-02-2013)“…Elevated androgen receptor (AR) activity in castration-resistant prostate cancer may occur through increased levels of AR co-activator proteins. Vav3, a…”
Get full text
Journal Article -
9
β-2 Spectrin Regulates Angiogenesis and Ischemic-Diabetic Wound Healing
Published in JVS-vascular science (2021)Get full text
Journal Article -
10
Gambogic acid reduced bcl-2 expression via p53 in human breast MCF-7 cancer cells
Published in Journal of cancer research and clinical oncology (01-12-2009)“…Purpose In this study, we investigated the correlation between p53 and bcl-2 in gambogic acid (GA)-induced apoptosis. Method MTT assay was employed to evaluate…”
Get full text
Journal Article -
11
Ligand-Independent Activation of Androgen Receptors by Rho GTPase Signaling in Prostate Cancer
Published in Molecular endocrinology (Baltimore, Md.) (01-03-2008)“…Prostate cancer invariably recurs after androgen deprivation therapy. Growth of this recurrent/androgen-independent form of prostate cancer may be due to…”
Get full text
Journal Article -
12
Targeting Transforming Growth Factor Beta Signaling in Liver Cancer
Published in Hepatology (Baltimore, Md.) (01-04-2019)Get full text
Journal Article -
13
Reply
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2020)Get full text
Journal Article -
14
Mo1619: MULTIPLE MECHANISMS FOR DYSREGULATED DE NOVO LIPOGENESIS CONVERGE ON SPTBN1
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2022)Get full text
Journal Article -
15
Analysis of Genomes and Transcriptomes of Hepatocellular Carcinomas Identifies Mutations and Gene Expression Changes in the Transforming Growth Factor-β Pathway
Published in Gastroenterology (New York, N.Y. 1943) (01-01-2018)“…Development of hepatocellular carcinoma (HCC) is associated with alterations in the transforming growth factor-beta (TGF-β) signaling pathway, which regulates…”
Get full text
Journal Article -
16
Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma
Published in Cancer research (Chicago, Ill.) (01-09-2019)“…Hepatocellular carcinoma (HCC) has emerged as a major cause of cancer deaths globally. The landscape of systemic therapy has recently changed, with six…”
Get full text
Journal Article -
17
-
18
Abstract 1984: Crosstalk between sirtuins and TGF-β signaling suppresses liver cancer
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Background: Cancer stem cells that escape suppression by key pathways such as TGF-β represent one of the mechanisms for poor prognosis in…”
Get full text
Journal Article -
19
Mutated CEACAMs Disrupt Transforming Growth Factor Beta Signaling and Alter the Intestinal Microbiome to Promote Colorectal Carcinogenesis
Published in Gastroenterology (New York, N.Y. 1943) (01-01-2020)“…We studied interactions among proteins of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family, which interact with microbes, and…”
Get full text
Journal Article -
20
450 DISRUPTION OF TGF-β SIGNALING PROMOTES LIVER DISEASES PROGRESSION FROM NAFLD/NASH TO HCC THROUGH SIRT6 REGULATION
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2021)Get full text
Journal Article