Search Results - "SHUMS, Zakera"

AFP, AFP-L3, DCP, and GP73 as markers for monitoring treatment response and recurrence and as surrogate markers of clinicopathological variables of HCC by Yamamoto, Kentaroh, Imamura, Hiroshi, Matsuyama, Yutaka, Kume, Yukio, Ikeda, Hitoshi, Norman, Gary L., Shums, Zakera, Aoki, Taku, Hasegawa, Kiyoshi, Beck, Yoshifumi, Sugawara, Yasuhiko, Kokudo, Norihiro

“…Background Alpha-fetoprotein (AFP), lens culinaris agglutinin-reactive fraction of AFP (AFP-L3), des-γ-carboxy prothrombin (DCP), and Golgi protein-73 (GP73)…”
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Novel Anti–Hexokinase 1 Antibodies Are Associated With Poor Prognosis in Patients With Primary Biliary Cholangitis by Reig, Anna, Norman, Gary L., Garcia, Mila, Shums, Zakera, Ruiz-Gaspà, Silvia, Bentow, Chelsea, Mahler, Michael, Romera, Maria A., Vinas, Odette, Pares, Albert

“…Antibodies to hexokinase 1 (HK1) and kelch-like 12 (KLHL12) have been identified as potential biomarkers in primary biliary cholangitis (PBC), and this study…”
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Gut barrier failure biomarkers are associated with poor disease outcome in patients with primary sclerosing cholangitis by Tornai, Tamas, Palyu, Eszter, Vitalis, Zsuzsanna, Tornai, Istvan, Tornai, David, Antal-Szalmas, Peter, Norman, Gary L, Shums, Zakera, Veres, Gabor, Dezsofi, Antal, Par, Gabriella, Par, Alajos, Orosz, Peter, Szalay, Ferenc, Lakatos, Peter Laszlo, Papp, Maria

“…AIM To assess the prevalence of a panel of serologic markers that reflect gut barrier dysfunction in a mixed cohort of pediatric and adult primary sclerosing…”
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Significance of serological markers in the disease course of ulcerative colitis in a prospective clinical cohort of patients by Kovacs, Gyorgy, Sipeki, Nora, Suga, Boglarka, Tornai, Tamas, Fechner, Kai, Norman, Gary L, Shums, Zakera, Antal-Szalmas, Peter, Papp, Maria

“…To determine the prognostic potential of classic and novel serologic antibodies regarding unfavorable disease course in a prospective ulcerative colitis (UC)…”
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Validity of the global anti-phospholipid syndrome score to predict thrombosis: a prospective multicentre cohort study by Zuily, Stéphane, de Laat, Bas, Mohamed, Shirine, Kelchtermans, Hilde, Shums, Zakera, Albesa, Roger, Norman, Gary L, Lamboux-Matthieu, Claire, Rat, Anne-Christine, Ninet, Jacques, Magy-Bertrand, Nadine, Pasquali, Jean-Louis, Lambert, Marc, Lorcerie, Bernard, Kaminsky, Pierre, Guillemin, Francis, Regnault, Véronique, Wahl, Denis

“…To investigate the validity of the global APS score (GAPSS) to predict thrombosis in patients with autoimmune diseases. This prospective cohort study included…”
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Prognostic implications of antibodies to Ro/SSA and soluble liver antigen in type 1 autoimmune hepatitis by Montano-Loza, Aldo J., Shums, Zakera, Norman, Gary L., Czaja, Albert J.

“…Background: Antibodies to soluble liver antigen are frequently co‐expressed with antibodies to ribonucleoprotein/Sjögren's syndrome A (Ro/SSA) in autoimmune…”
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Anti‐gp210 and anti‐centromere antibodies are different risk factors for the progression of primary biliary cirrhosis by Nakamura, Minoru, Kondo, Hisayoshi, Mori, Tsuyoshi, Komori, Atsumasa, Matsuyama, Mutsumi, Ito, Masahiro, Takii, Yasushi, Koyabu, Makiko, Yokoyama, Terufumi, Migita, Kiyoshi, Daikoku, Manabu, Abiru, Seigo, Yatsuhashi, Hiroshi, Takezaki, Eiichi, Masaki, Naohiko, Sugi, Kazuhiro, Honda, Koichi, Adachi, Hiroshi, Nishi, Hidehiro, Watanabe, Yukio, Nakamura, Yoko, Shimada, Masaaki, Komatsu, Tatsuji, Saito, Akira, Saoshiro, Takeo, Harada, Hideharu, Sodeyama, Takeshi, Hayashi, Shigeki, Masumoto, Akihide, Sando, Takehiro, Yamamoto, Tetsuo, Sakai, Hironori, Kobayashi, Masakazu, Muro, Toyokichi, Koga, Michiaki, Shums, Zakera, Norman, Gary L., Ishibashi, Hiromi

“…The predictive role of antinuclear antibodies (ANAs) remains elusive in the long‐term outcome of primary biliary cirrhosis (PBC). The progression of PBC was…”
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Utility of Antiphosphatidylserine/Prothrombin and IgA Antiphospholipid Assays in Systemic Lupus Erythematosus by AKHTER, Ehtisham, SHUMS, Zakera, NORMAN, Gary L, BINDER, Walter, HONG FANG, PETRI, Michelle

“…Currently, 3 antiphospholipid assays are widely used clinically [lupus anticoagulant (LAC), anticardiolipin (aCL), and anti-ß2-glycoprotein I (anti-ß2-GPI)]…”
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Anti-kelch-like 12 and anti-hexokinase 1: novel autoantibodies in primary biliary cirrhosis by Norman, Gary L., Yang, Chen-Yen, Ostendorff, Heather P., Shums, Zakera, Lim, Mark J., Wang, Jinjun, Awad, Amany, Hirschfield, Gideon M., Milkiewicz, Piotr, Bloch, Donald B., Rothschild, Kenneth J., Bowlus, Christopher L., Adamopoulos, Iannis E., Leung, Patrick S.C., Janssen, Harry J., Cheung, Angela C., Coltescu, Catalina, Gershwin, M. Eric

“…Background & Aims Using high‐density human recombinant protein microarrays, we identified two potential biomarkers, kelch‐like 12 (KLHL12) and hexokinase‐1…”
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Association between serum soluble CD14 and IL‐8 levels and clinical outcome in primary biliary cholangitis by Umemura, Takeji, Sekiguchi, Tomohiro, Joshita, Satoru, Yamazaki, Tomoo, Fujimori, Naoyuki, Shibata, Soichiro, Ichikawa, Yuki, Komatsu, Michiharu, Matsumoto, Akihiro, Shums, Zakera, Norman, Gary L., Tanaka, Eiji, Ota, Masao

“…Background & Aims Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by portal inflammation and immune‐mediated destruction of…”
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PBC Screen: An IgG/IgA dual isotype ELISA detecting multiple mitochondrial and nuclear autoantibodies specific for primary biliary cirrhosis by Liu, Haiying, Norman, Gary L, Shums, Zakera, Worman, Howard J, Krawitt, Edward L, Bizzaro, Nicola, Vergani, Diego, Bogdanos, Dimitrios P, Dalekos, George N, Milkiewicz, Piotr, Czaja, Albert J, Heathcote, E. Jenny, Hirschfield, Gideon M, Tan, Eng M, Miyachi, Kiyomitsu, Bignotto, Monica, Battezzati, Pier Maria, Lleo, Ana, Leung, Patrick S, Podda, Mauro, Gershwin, M. Eric, Invernizzi, Pietro

“…Abstract A dual isotype (IgG, IgA) enzyme-linked immunosorbent assay (ELISA) designed to provide enhanced detection of primary biliary cirrhosis (PBC)-specific…”
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Anti-phosphatidylserine/prothrombin antibodies: an additional diagnostic marker for APS? by Pregnolato, Francesca, Chighizola, Cecilia B., Encabo, Susan, Shums, Zakera, Norman, Gary L., Tripodi, Armando, Chantarangkul, Veena, Bertero, Tiziana, De Micheli, Valeria, Borghi, Maria Orietta, Meroni, Pier Luigi

“…Among the diagnostic assays for anti-phospholipid syndrome (APS), lupus anticoagulant (LA) is the strongest predictor of thrombosis; however, it presents…”
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The Diagnostic Value of Anti-Parietal Cell and Intrinsic Factor Antibodies, Pepsinogens, and Gastrin-17 in Corpus-Restricted Atrophic Gastritis by Kriķe, Petra, Shums, Zakera, Poļaka, Inese, Kikuste, Ilze, Vanags, Aigars, Tolmanis, Ivars, Isajevs, Sergejs, Liepniece-Karele, Inta, Santare, Daiga, Tzivian, Lilian, Rudzīte, Dace, Song, Minkyo, Camargo, M Constanza, Norman, Gary L, Leja, Mārcis

“…We aimed to determine the diagnostic value of anti-parietal cell antibodies (anti-PCA), anti-intrinsic factor antibodies (anti-IFA), pepsinogen ratio (PGI/II),…”
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Presence of anti-microbial antibodies in liver cirrhosis--a tell-tale sign of compromised immunity? by Papp, Maria, Norman, Gary L, Vitalis, Zsuzsanna, Tornai, Istvan, Altorjay, Istvan, Foldi, Ildiko, Udvardy, Miklos, Shums, Zakera, Dinya, Tamas, Orosz, Peter, Lombay, Jr, Bela, Par, Gabriella, Par, Alajos, Veres, Gabor, Csak, Timea, Osztovits, Janos, Szalay, Ferenc, Lakatos, Peter Laszlo

“…Bacterial translocation plays important role in the complications of liver cirrhosis. Antibody formation against various microbial antigens is common in…”
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Value of Autoantibody Analysis in the Differential Diagnosis of Chronic Cholestatic Liver Disease by Milkiewicz, Piotr, Buwaneswaran, Hayman, Coltescu, Catalina, Shums, Zakera, Norman, Gary L, Heathcote, E. Jenny

“…Background & Aims It is challenging to diagnose patients with chronic cholestatic liver diseases when all the classic criteria are not fulfilled. We evaluated…”
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Comparative analysis of different enzyme immunoassays for assessment of phosphatidylserine-dependent antiprothrombin antibodies by Amengual, Olga, Horita, Tetsuya, Binder, Walter, Norman, Gary L., Shums, Zakera, Kato, Masaru, Otomo, Kotaro, Fujieda, Yuichiro, Oku, Kenji, Bohgaki, Toshiyuki, Yasuda, Shinsuke, Atsumi, Tatsuya

“…Phosphatidylserine-dependent antiprothrombin antibodies (aPS/PT) were strongly correlated with the presence of lupus anticoagulant showing a high specificity…”
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Prevalence estimation of celiac disease in the general adult population of Latvia using serology and HLA genotyping by Leja, Marcis, Shums, Zakera, Nikitina-Zake, Liene, Gavars, Mikus, Kikuste, Ilze, Milo, Jay, Daugule, Ilva, Pahomova, Jelena, Pirags, Valdis, Dzerve, Vilnis, Klovins, Janis, Erglis, Andrejs, Norman, Gary L

“…Background Prevalence estimates for celiac disease (CD) depend on the method used. The role of deamidated gliadin peptide (DGP) and genetic testing in…”
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High prevalence of primary biliary cirrhosis and disease-associated autoantibodies in Japanese patients with systemic sclerosis by Imura-Kumada, Sayako, Hasegawa, Minoru, Matsushita, Takashi, Hamaguchi, Yasuhito, Encabo, Susan, Shums, Zakera, Norman, Gary L., Takehara, Kazuhiko, Fujimoto, Manabu

“…Abstract Objective To investigate the prevalence of primary biliary cirrhosis (PBC) and PBC-associated autoantibodies in Japanese systemic sclerosis (SSc)…”
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TRAF1 Gene Polymorphism Correlates with the Titre of Gp210 Antibody in Patients with Primary Biliary Cirrhosis by Milkiewicz, Piotr, Bogdanos, Dimitrios P., Milkiewicz, Malgorzata, Wunsch, Ewa, Wasilewicz, Michał, Shums, Zakera, Kempinska-Podhorodecka, Agnieszka, Norman, Gary L.

“…Background. Polymorphisms of TRAF1 (Tumor necrosis factor receptor-associated factor 1) are associated with rheumatoid arthritis (RA). Whether TRAF1…”
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Frequency and Significance of Antibodies to Soluble Liver Antigen/Liver Pancreas in Variant Autoimmune Hepatitis by Czaja, Albert J., Shums, Zakera, Norman, Gary L.

“…Background: Antibodies to soluble liver antigen/liver pancreas are highly specific markers of autoimmune hepatitis. Aims: Determine the frequency and clinical…”
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