Search Results - "SHRIVER, Craig D"
-
1
Molecular heterogeneity in breast cancer: State of the science and implications for patient care
Published in Seminars in cell & developmental biology (01-04-2017)“…The identification of extensive genetic heterogeneity in human breast carcinomas poses a significant challenge for designing effective treatment regimens…”
Get full text
Journal Article -
2
Incidence rates of digestive cancers among U.S. military servicemen: Comparison with the rates in the general U.S. population
Published in PloS one (03-09-2021)“…Digestive cancers greatly contribute to the cancer burden in the United States. These cancers are more common among men and some are increasing among adults…”
Get full text
Journal Article -
3
Functional role of vitronectin in breast cancer
Published in PloS one (19-11-2020)“…Breast Cancer is the most common form of cancer in women worldwide, impacting nearly 2.1 million women each year. Identification of new biomarkers could be key…”
Get full text
Journal Article -
4
Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas
Published in JAMA oncology (01-12-2017)“…African Americans have the highest breast cancer mortality rate. Although racial difference in the distribution of intrinsic subtypes of breast cancer is…”
Get more information
Journal Article -
5
Selection of optimal quantile protein biomarkers based on cell-level immunohistochemistry data
Published in BMC bioinformatics (22-07-2023)“…Protein biomarkers of cancer progression and response to therapy are increasingly important for improving personalized medicine. Advanced quantitative…”
Get full text
Journal Article -
6
Effect of ASCO/CAP Guidelines for Determining ER Status on Molecular Subtype
Published in Annals of surgical oncology (01-01-2013)“…Background Determination of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) status is standard for…”
Get full text
Journal Article -
7
Cancer stage at diagnosis: Comparison of insurance status in SEER to the Department of Defense Cancer Registry
Published in Cancer medicine (Malden, MA) (01-11-2023)“…Background Military individuals, retirees, and their families have free care or minimal out‐of‐pocket costs in the US military health system (MHS). In…”
Get full text
Journal Article -
8
Assessing the quality of RNA isolated from human breast tissue after ambient room temperature exposure
Published in PloS one (18-01-2022)“…High quality human tissue is essential for molecular research, but pre-analytical conditions encountered during tissue collection could degrade tissue RNA. We…”
Get full text
Journal Article -
9
Impact of age at diagnosis on racial disparities in endometrial cancer patients
Published in Gynecologic oncology (01-04-2018)“…Although black patients with endometrial cancer (EC) have worse survival compared with white patients, the interaction between age/race has not been examined…”
Get full text
Journal Article -
10
Proteogenomic characterization of difficult-to-treat breast cancer with tumor cells enriched through laser microdissection
Published in Breast cancer research : BCR (14-05-2024)“…Breast cancer (BC) is the most commonly diagnosed cancer and the leading cause of cancer death among women globally. Despite advances, there is considerable…”
Get full text
Journal Article -
11
Eligibility, uptake and response to germline genetic testing in women with DCIS
Published in Frontiers in oncology (26-08-2022)“…Ductal carcinoma (DCIS) is a malignant, yet pre-invasive disease of the breast. While the majority of DCIS have low risk of recurrence, a subset of women with…”
Get full text
Journal Article -
12
Role for chondroitin sulfate glycosaminoglycan in NEDD9-mediated breast cancer cell growth
Published in Experimental cell research (15-01-2015)“…There are lines of evidence demonstrating that NEDD9 (Cas-L, HEF-1) plays a key role in the development, progression, and metastasis of breast cancer cells. We…”
Get full text
Journal Article -
13
The Impact of Preexisting Mental Health Disorders on the Diagnosis, Treatment, and Survival among Lung Cancer Patients in the U.S. Military Health System
Published in Cancer epidemiology, biomarkers & prevention (01-12-2016)“…Higher cancer-related mortality has been observed among people with mental health disorders than in the general population. Both delay in diagnosis and…”
Get full text
Journal Article -
14
Management of Incidental Findings in the Era of Next-generation Sequencing
Published in Current genomics (01-06-2015)“…Next-generation sequencing (NGS) technologies allow for the generation of whole exome or whole genome sequencing data, which can be used to identify novel…”
Get full text
Journal Article -
15
Chemotherapy Treatment Costs and Clinical Outcomes of Colon Cancer in the U.S. Military Health System’s Direct and Private Sector Care Settings
Published in Military medicine (03-11-2023)“…ABSTRACT Introduction Identifying low-value cancer care may be an important step in containing costs associated with treatment. Low-value care occurs when the…”
Get full text
Journal Article -
16
DNA aptamers against exon v10 of CD44 inhibit breast cancer cell migration
Published in PloS one (19-02-2014)“…CD44 adhesion molecules are expressed in many breast cancer cells and have been demonstrated to play a key role in regulating malignant phenotypes such as…”
Get full text
Journal Article -
17
Validation of tumor protein marker quantification by two independent automated immunofluorescence image analysis platforms
Published in Modern pathology (01-10-2016)“…Protein marker levels in formalin-fixed, paraffin-embedded tissue sections traditionally have been assayed by chromogenic immunohistochemistry and evaluated…”
Get full text
Journal Article -
18
Does Breast Tumor Heterogeneity Necessitate Further Immunohistochemical Staining on Surgical Specimens?
Published in Journal of the American College of Surgeons (01-02-2013)“…Background Prognostic and predictive tumor markers in breast cancer are most commonly performed on core needle biopsies (CNB) of the primary tumor. Because…”
Get full text
Journal Article -
19
Breast Cancer in the Personal Genomics Era
Published in Current genomics (01-05-2010)“…Breast cancer is a heterogeneous disease with a complex etiology that develops from different cellular lineages, progresses along multiple molecular pathways,…”
Get full text
Journal Article -
20
Single-cell sequencing and tumorigenesis: improved understanding of tumor evolution and metastasis
Published in Clinical and translational medicine (01-12-2017)“…Extensive genomic and transcriptomic heterogeneity in human cancer often negatively impacts treatment efficacy and survival, thus posing a significant ongoing…”
Get full text
Journal Article