Search Results - "SHRAGER, Joseph"
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A molecular cell atlas of the human lung from single-cell RNA sequencing
Published in Nature (London) (26-11-2020)“…Although single-cell RNA sequencing studies have begun to provide compendia of cell expression profiles 1 – 9 , it has been difficult to systematically…”
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Commentary: Progress, or just movement, on thymoma staging?
Published in The Journal of thoracic and cardiovascular surgery (01-04-2021)Get full text
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Commentary: Can the esophagus curse a lung transplant?
Published in The Journal of thoracic and cardiovascular surgery (01-12-2020)Get full text
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Mapping lung cancer epithelial-mesenchymal transition states and trajectories with single-cell resolution
Published in Nature communications (06-12-2019)“…Elucidating the spectrum of epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) states in clinical samples promises insights on…”
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New Information on Talc and Mesothelioma
Published in The Annals of thoracic surgery (01-09-2020)Get full text
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Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss
Published in Nature communications (20-06-2017)“…Volumetric muscle loss (VML) is associated with loss of skeletal muscle function, and current treatments show limited efficacy. Here we show that bioconstructs…”
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7
Talc Pleurodesis: A Medical, Medicolegal, and Socioeconomic Review
Published in The Annals of thoracic surgery (01-04-2020)“…Talcum has been used in pleurodesis for more than 8 decades. Despite a wealth of research, controversy remains over the optimal sclerosant for pneumothorax and…”
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8
The Signaling Network Resulting in Ventilator-induced Diaphragm Dysfunction
Published in American journal of respiratory cell and molecular biology (01-10-2018)“…Mechanical ventilation (MV) is a life-saving measure for those incapable of adequately ventilating or oxygenating without assistance. Unfortunately, even brief…”
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GFPT2 -Expressing Cancer-Associated Fibroblasts Mediate Metabolic Reprogramming in Human Lung Adenocarcinoma
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Metabolic reprogramming of the tumor microenvironment is recognized as a cancer hallmark. To identify new molecular processes associated with tumor metabolism,…”
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We should be considering lung cancer screening for never-smoking Asian American females
Published in The Journal of thoracic and cardiovascular surgery (01-07-2024)Get full text
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Integrated digital error suppression for improved detection of circulating tumor DNA
Published in Nature biotechnology (01-05-2016)“…Circulating tumor DNA is detected with high sensitivity and specificity using molecular barcoding and in silico error correction. High-throughput sequencing of…”
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Ex Vivo Expansion and In Vivo Self-Renewal of Human Muscle Stem Cells
Published in Stem cell reports (13-10-2015)“…Adult skeletal muscle stem cells, or satellite cells (SCs), regenerate functional muscle following transplantation into injured or diseased tissue. To gain…”
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Stage IB: To give (chemo), or not to give? That is the question
Published in The Journal of thoracic and cardiovascular surgery (01-03-2018)Get full text
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An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
Published in Nature medicine (01-05-2014)“…Aaron Newman and his colleagues introduce a next-generation sequencing–based approach for the cost-effective detection and quantitation of tumor-derived…”
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15
Rapamycin protects aging muscle
Published in Aging (Albany, NY.) (27-08-2019)Get full text
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Randomized Trial of Thymectomy in Myasthenia Gravis
Published in The New England journal of medicine (17-11-2016)Get full text
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Non-Small Cell Lung Cancer Radiogenomics Map Identifies Relationships between Molecular and Imaging Phenotypes with Prognostic Implications
Published in Radiology (01-01-2018)“…Purpose To create a radiogenomic map linking computed tomographic (CT) image features and gene expression profiles generated by RNA sequencing for patients…”
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Thoracoscopic lobectomy is associated with acceptable morbidity and mortality in patients with predicted postoperative forced expiratory volume in 1 second or diffusing capacity for carbon monoxide less than 40% of normal
Published in The Journal of thoracic and cardiovascular surgery (01-07-2014)“…Objective A predicted postoperative (ppo) forced expiratory volume in 1 second (FEV1%) or diffusing capacity of the lung for carbon monoxide (DLCO%) of <40%…”
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Lymph Node Evaluation Achieved by Open Lobectomy Compared With Thoracoscopic Lobectomy for N0 Lung Cancer
Published in The Annals of thoracic surgery (01-10-2013)“…Background Controversy remains regarding the adequacy of the lymph node evaluation achieved by video-assisted thoracic surgery (VATS) lobectomy for lung…”
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CRISPR/Cas‐mediated genome editing to treat EGFR‐mutant lung cancer: a personalized molecular surgical therapy
Published in EMBO molecular medicine (01-02-2016)“…While substantial progress has been made in the treatment of lung cancer with the development of tyrosine kinase inhibitors (TKIs) that target tumor‐driving…”
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