Search Results - "SHRAGER, Joseph"

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    Mapping lung cancer epithelial-mesenchymal transition states and trajectories with single-cell resolution by Karacosta, Loukia G., Anchang, Benedict, Ignatiadis, Nikolaos, Kimmey, Samuel C., Benson, Jalen A., Shrager, Joseph B., Tibshirani, Robert, Bendall, Sean C., Plevritis, Sylvia K.

    Published in Nature communications (06-12-2019)
    “…Elucidating the spectrum of epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) states in clinical samples promises insights on…”
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    Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss by Quarta, Marco, Cromie, Melinda, Chacon, Robert, Blonigan, Justin, Garcia, Victor, Akimenko, Igor, Hamer, Mark, Paine, Patrick, Stok, Merel, Shrager, Joseph B., Rando, Thomas A.

    Published in Nature communications (20-06-2017)
    “…Volumetric muscle loss (VML) is associated with loss of skeletal muscle function, and current treatments show limited efficacy. Here we show that bioconstructs…”
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    Talc Pleurodesis: A Medical, Medicolegal, and Socioeconomic Review by Baiu, Ioana, Yevudza, Elorm, Shrager, Joseph B.

    Published in The Annals of thoracic surgery (01-04-2020)
    “…Talcum has been used in pleurodesis for more than 8 decades. Despite a wealth of research, controversy remains over the optimal sclerosant for pneumothorax and…”
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    The Signaling Network Resulting in Ventilator-induced Diaphragm Dysfunction by Tang, Huibin, Shrager, Joseph B

    “…Mechanical ventilation (MV) is a life-saving measure for those incapable of adequately ventilating or oxygenating without assistance. Unfortunately, even brief…”
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    Ex Vivo Expansion and In Vivo Self-Renewal of Human Muscle Stem Cells by Charville, Gregory W., Cheung, Tom H., Yoo, Bryan, Santos, Pauline J., Lee, Gordon K., Shrager, Joseph B., Rando, Thomas A.

    Published in Stem cell reports (13-10-2015)
    “…Adult skeletal muscle stem cells, or satellite cells (SCs), regenerate functional muscle following transplantation into injured or diseased tissue. To gain…”
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    An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage by Newman, Aaron M, Bratman, Scott V, To, Jacqueline, Wynne, Jacob F, Eclov, Neville C W, Modlin, Leslie A, Liu, Chih Long, Neal, Joel W, Wakelee, Heather A, Merritt, Robert E, Shrager, Joseph B, Loo, Billy W, Alizadeh, Ash A, Diehn, Maximilian

    Published in Nature medicine (01-05-2014)
    “…Aaron Newman and his colleagues introduce a next-generation sequencing–based approach for the cost-effective detection and quantitation of tumor-derived…”
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    Non-Small Cell Lung Cancer Radiogenomics Map Identifies Relationships between Molecular and Imaging Phenotypes with Prognostic Implications by Zhou, Mu, Leung, Ann, Echegaray, Sebastian, Gentles, Andrew, Shrager, Joseph B, Jensen, Kristin C, Berry, Gerald J, Plevritis, Sylvia K, Rubin, Daniel L, Napel, Sandy, Gevaert, Olivier

    Published in Radiology (01-01-2018)
    “…Purpose To create a radiogenomic map linking computed tomographic (CT) image features and gene expression profiles generated by RNA sequencing for patients…”
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    Lymph Node Evaluation Achieved by Open Lobectomy Compared With Thoracoscopic Lobectomy for N0 Lung Cancer by Merritt, Robert E., MD, Hoang, Chuong D., MD, Shrager, Joseph B., MD

    Published in The Annals of thoracic surgery (01-10-2013)
    “…Background Controversy remains regarding the adequacy of the lymph node evaluation achieved by video-assisted thoracic surgery (VATS) lobectomy for lung…”
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    CRISPR/Cas‐mediated genome editing to treat EGFR‐mutant lung cancer: a personalized molecular surgical therapy by Tang, Huibin, Shrager, Joseph B

    Published in EMBO molecular medicine (01-02-2016)
    “…While substantial progress has been made in the treatment of lung cancer with the development of tyrosine kinase inhibitors (TKIs) that target tumor‐driving…”
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