Search Results - "SHOWS, Thomas B"

New members of the chemokine receptor gene family by C J Raport, V L Schweickart, D Chantry, R L Eddy, Jr, T B Shows, R Godiska, P W Gray

“…Chemokines are relatively small peptides with potent chemoattractant and activation activities for leukocytes. Several chemokine receptors have been cloned and…”
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Molecular Genetics of Inherited Variation in Human Color Vision by Nathans, Jeremy, Piantanida, Thomas P., Eddy, Roger L., Shows, Thomas B., Hogness, David S.

“…The hypothesis that red-green ``color blindness'' is caused by alterations in the genes encoding red and green visual pigments has been tested and shown to be…”
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Human substance P receptor (NK-1): organization of the gene, chromosome localization and functional expression of cDNA clones by Gerard, Norma P, Garraway, Levi A, Eddy, Roger L, Shows, Thomas B, Iijima, Hideya, Paquet, Jean Luc, Gerard, Craig

“…The gene for the human substance P receptor (NK-1) was cloned using cDNA probes made by the polymerase chain reaction from primers based on the rat sequence…”
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Human chemotaxis receptor genes cluster at 19q13.3-13.4. Characterization of the human C5a receptor gene by Gerard, Norma P, Bao, Lu, He, Xiao Ping, Eddy, Roger L, Shows, Thomas B, Gerard, Craig

“…The human C5a anaphylatoxin and formyl peptide receptor genes, as well as two genes with high sequence identity to the formyl peptide receptor, FPRH1 and…”
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NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia by RAZA-EGILMEZ, S. Z, JANI-SAIT, S. N, GROSSI, M, HIGGINS, M. J, SHOWS, T. B, APLAN, P. D

“…A novel chromosomal translocation, t(2;11)(q31;p15), was identified in a patient with therapy-related acute myelogenous leukemia (t-AML). Fluorescence in situ…”
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Intrachromosomal genomic instability in human sporadic colorectal cancer measured by genome-wide allelotyping and inter-(simple sequence repeat) PCR by ANDERSON, Garth R, BRENNER, Bruce M, JAHREIS, Gerald P, KAHLENBERG, Morton S, BASIK, Mark, SAIT, Sheila, RODRIGUEZ-BIGAS, Miguel A, NOWAK, Norma J, PETRELLI, Nicholas J, SHOWS, Thomas B, STOLER, Daniel L, SWEDE, Helen, NENG CHEN, HENRY, W. Michael, CONROY, Jeffrey M, KARPENKO, Matthew J, ISSA, Jean-Pierre, BARTOS, Jeremy D, BRUNELLE, Joslyn K

“…We have used genome-wide allelotyping with 348 polymorphic autosomal markers spaced, on average, 10 cM apart to quantitate the extent of intrachromosomal…”
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Brn-3b: a POU domain gene expressed in a subset of retinal ganglion cells by Xiang, M, Zhou, L, Peng, Y W, Eddy, R L, Shows, T B, Nathans, J

“…A search for POU domain transcription factors in human retina cDNA has led to the identification of Brn-3b, a class IV POU domain protein. Immunohistochemical…”
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Fine Structure Analysis of the WT1 Gene in Sporadic Wilms Tumors by Varanasi, Ramani, Bardeesy, Nabeel, Ghahremani, Majid, Petruzzi, Mary-Jane, Nowak, Norma, Adam, Mohammed A., Grundy, Paul, Shows, Thomas B., Pelletier, Jerry

“…Molecular genetic studies indicate that the etiology of Wilms tumor (WT) is complex, involving at least three loci. Germ-line mutations in the tumor suppressor…”
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Linkage-disequilibrium mapping without genotyping by Cheung, Vivian G, Gregg, Jeffrey P, Gogolin-Ewens, Kathryn J, Bandong, Jonathan, Stanley, Charles A, Baker, Lester, Higgins, Michael J, Nowak, Norma J, Shows, Thomas B, Ewens, Warren J, Nelson, Stanley F, Spielman, Richard S

“…Genomic mismatch scanning (GMS) is a technique that enriches for regions of identity by descent (IBD) between two individuals without the need for genotyping…”
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cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines by Betsholtz, Christer, Johnsson, Ann, Heldin, Carl-Henrik, Westermark, Bengt, Lind, Peter, Urdea, Mickey S, Eddy, Roger, Shows, Thomas B, Philpott, Karen, Mellor, Andrew L, Knott, Timothy J, Scott, James

“…The amino-acid sequence of the precursor of the human tumour cell line-derived platelet-derived growth factor (PDGF) A-chain has been deduced from…”
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Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19 by Bao, L, Gerard, N P, Eddy, Jr, R L, Shows, T B, Gerard, C

“…The genes encoding receptors for the chemotactic ligands C5a (C5AR) and FMLP (FPR) were mapped using a panel of somatic cell hybrids to chromosome 19. Because…”
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The orphan G-protein-coupled receptor-encoding gene V28 is closely related to genes for chemokine receptors and is expressed in lymphoid and neural tissues by Raport, Carol J., Schweickart, Vicki L., Eddy, Roger L., Shows, Thomas B., Gray, Patrick W.

“…A polymerase chain reaction (PCR) strategy with degenerate primers was used to identify novel G-protein-coupled receptor-encoding genes from human genomic DNA…”
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Human, Mouse, and Rat Calnexin cDNA Cloning: Identification of Potential Calcium Binding Motifs and Gene Localization to Human Chromosome 5 by Tjoelker, Larry W, Seyfried, Christine E, Eddy, Roger L, Byers, Mary G, Shows, Thomas B, Calderon, Jesus, Schreiber, Robert B, Gray, Patrick W

“…Calnexin is a 90-kDa integral membrane protein of the endoplasmic reticulum (ER). Calnexin binds Ca2+ and may function as a chaperone in the transition of…”
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Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas by TRICOLI, J. V, RALL, L. B, KARAKOUSIS, C. P, HERRERA, L, PETRELLI, N. J, BELL, G. I, SHOWS, T. B

“…The insulin-like growth factors I and II (IGF-I and -II) are proteins which stimulate cell proliferation and are important in normal human growth and…”
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Nonspecific integration of the HTLV provirus genome into adult T-cell leukaemia cells by Seiki, Motoharu, Eddy, Roger, Shows, Thomas B, Yoshida, Mitsuaki

“…Human T-cell leukaemia virus (HTLV), previously also reported as ATLV, is a recently identified retrovirus which is closely associated with adult T-cell…”
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The Mammalian Homologue of Mago Nashi Encodes a Serum-Inducible Protein by Zhao, Xian-Feng, Colaizzo-Anas, Tina, Nowak, Norma J., Shows, Thomas B., Elliott, Rosemary W., Aplan, Peter D.

“…The products of at least 11 maternal effect genes have been shown to be essential for proper germ plasm assembly inDrosophila melanogasterembryos. Here we…”
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Structure and Chromosomal Localization of the Human Salivary Mucin Gene, MUC7 by Bobek, Libuse A., Liu, Jianhua, Sait, Sheila N.J., Shows, Thomas B., Bobek, Yvonne A., Levine, Michael J.

“…We have isolated and characterized several MUC7 genomic clones encoding the human low-molecular-weight salivary mucin, MG2. The MUC7 gene spans ∼10.0 kb and…”
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cDNA cloning and chromosomal assignment of the endothelin 2 gene: vasoactive intestinal contractor peptide is rat endothelin 2 by Bloch, K D, Hong, C C, Eddy, R L, Shows, T B, Quertermous, T

“…Four members of the endothelin family of vasoactive and mitogenic peptides have been identified: human endothelins 1, 2, and 3 (ET1, ET2, and ET3,…”
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The human connexin gene family of gap junction proteins: distinct chromosomal locations but similar structures by Fishman, G I, Eddy, R L, Shows, T B, Rosenthal, L, Leinwand, L A

“…Connexins are protein subunits that constitute gap junction channels. Two members of this gene family, connexin43 (Cx43) and connexin32 (Cx32), are abundantly…”
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Comparative Structure, Proximal Promoter Elements, and Chromosome Location of the Human Eosinophil Major Basic Protein Genes by Plager, Douglas A., Weiler, Deborah A., Loegering, David A., Johnson, William B., Haley, Linda, Eddy, Roger L., Shows, Thomas B., Gleich, Gerald J.

“…Human eosinophil major basic protein (MBP) is strongly implicated as a mediator of disease, especially bronchial asthma. We recently isolated a highly…”
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