Search Results - "SHOBE, E. M"

Pharmacokinetics, Metabolism, and Excretion of Linezolid following an Oral Dose of [14C]Linezolid to Healthy Human Subjects by SLATTER, J. G, STALKER, D. J, STRYD, R. P, PENG, G. W, SHOBE, E. M, FEENSTRA, K. L, WELSHMAN, I. R, BRUSS, J. B, SAMS, J. P, JOHNSON, M. G, SANDERS, P. E, HAUER, M. J, FAGERNESS, P. E

“…Linezolid (Zyvox), the first of a new class of antibiotics, the oxazolidinones, is approved for treatment of Gram-positive bacterial infections, including…”
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Development of a sensitive bioanalytical method for determination of PNU-83757 in rat, monkey and human plasma: from LC-UV to LC-MS/MS by Williams, M.G, Shobe, E.M, Bothwell, B.E, Zhong, W.Z

“…To support pre-clinical pharmacokinetic/toxicokinetic (PK/TK) evaluation, a sensitive bioanalytical method for determination of N-cyano- N′-( tert-pentyl)-…”
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Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Potent Antibacterial Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalis by Genin, Michael J, Hutchinson, Douglas K, Allwine, Debra A, Hester, Jackson B, Emmert, D. Edward, Garmon, Stuart A, Ford, Charles W, Zurenko, Gary E, Hamel, Judith C, Schaadt, Ronda D, Stapert, Douglas, Yagi, Betty H, Friis, Janice M, Shobe, Eric M, Adams, Wade J

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Thromboxane and prostacyclin production in ponies with colonic volvulus by Stick, J A, Arden, W A, Robinson, R A, Shobe, E M, Roth, R A

“…Effects of 1 hour of colonic volvulus and 3 hours of reperfusion on concentrations of thromboxane (TXB2) and prostacyclin (6-keto-PGF1 alpha) in portal,…”
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Predicting oral absorption of drugs: A case study with a novel class of antimicrobial agents by HILGERS, Allen R, SMITH, Donald P, SHONE, Eric M, BURTON, Philip S, BIERMACHER, John J, DAY, Jeffrey S, JENSEN, Jana L, SIMS, Sandra M, ADAMS, Wade J, FRIIS, Janice M, PALANDRA, Joe, HOSLEY, John D

“…The purpose of this work was to evaluate an oral absorption prediction model, maximum absorbable dose (MAD), which predicts a theoretical dose of drug that…”
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Rapid determination of rat plasma uridine levels by HPLC-ESI-MS utilizing the Captiva™ filter plates for sample preparation by Williams, Marta G., Palandra, Joe, Shobe, Eric M.

“…A rapid, accurate and precise HPLC‐ESI‐MS method for the determination of rat plasma uridine concentrations was developed and is described here. Sample…”
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