Search Results - "SHLYAPNIKOV, Yuri M"

Antitumor Effect of Bleomycin Nanoaerosol in Murine Carcinoma Model by Karshieva, Saida S, Babayeva, Gulalek, Pokrovsky, Vadim S, Shlyapnikov, Yuri M, Shlyapnikova, Elena A, Bugrova, Anna E, Kononikhin, Alexey S, Nikolaev, Evgeny N, Kanev, Igor L

“…Bleomycin, which is widely used as an antitumor agent, possesses serious adverse effects such as pulmonary toxicity. Local nanoaerosol deposition for lung…”
Get full text

Amyloid Aggregates of Smooth-Muscle Titin Impair Cell Adhesion by Bobylev, Alexander G, Fadeev, Roman S, Bobyleva, Liya G, Kobyakova, Margarita I, Shlyapnikov, Yuri M, Popov, Daniil V, Vikhlyantsev, Ivan M

“…Various amyloid aggregates, in particular, aggregates of amyloid β-proteins, demonstrate in vitro and in vivo cytotoxic effects associated with impairment of…”
Get full text

Reversible and Irreversible Mechanical Damaging of Large Double-Stranded DNA upon Electrospraying by Shlyapnikov, Yuri M, Shlyapnikova, Elena A, Morozov, Victor N

“…Electrohydrodynamic spraying (or electrospaying, ES) of DNA solutions is an attractive technique for applications in mass spectrometry, in microarray…”
Get full text

ECM-Mimetic Nylon Nanofiber Scaffolds for Neurite Growth Guidance by Antonova, Olga Y, Kochetkova, Olga Y, Shlyapnikov, Yuri M

“…Numerous nanostructured synthetic scaffolds mimicking the architecture of the natural extracellular matrix (ECM) have been described, but the polymeric…”
Get full text

Synergistic Antimicrobial Effect of Cold Atmospheric Plasma and Redox-Active Nanoparticles by Ermakov, Artem M, Afanasyeva, Vera A, Lazukin, Alexander V, Shlyapnikov, Yuri M, Zhdanova, Elizaveta S, Kolotova, Anastasia A, Blagodatski, Artem S, Ermakova, Olga N, Chukavin, Nikita N, Ivanov, Vladimir K, Popov, Anton L

“…Cold argon plasma (CAP) and metal oxide nanoparticles are well known antimicrobial agents. In the current study, on an example of Escherichia coli, a series of…”
Get full text

Can new immunoassay techniques improve bladder cancer diagnostics With protein biomarkers? by Shlyapnikov, Yuri M, Malakhova, Ekaterina A, Vinarov, Andrey Z, Zamyatnin, Jr, Andrey A, Shlyapnikova, Elena A

“…The search for new diagnostic tests for cancer or ways to improve existing tests is primarily driven by the desire to identify the disease as early as…”
Get full text

Rapid Amplification-Free Microarray-Based Ultrasensitive Detection of DNA by Shlyapnikov, Yuri M, Malakhova, Ekaterina A, Shlyapnikova, Elena A

“…We present a multiplex microarray-based assay of DNA fragments, which allows the detection of less than 10000 DNA fragments in a sample of 100 μL…”
Get full text

Improving Immunoassay Performance with Cleavable Blocking of Microarrays by Shlyapnikov, Yuri M, Malakhova, Ekaterina A, Shlyapnikova, Elena A

“…Among the key issues that are commonly associated with the development of microarray-based assays are nonspecific binding and diffusion constraints. Here we…”
Get full text

Rapid Ultrasensitive Gel-Free Immunoblotting with Magnetic Labels by Shlyapnikov, Yuri M, Kanev, Igor L, Shlyapnikova, Elena A

“…Immunoblotting is widely used for the detection of proteins using specific antibodies. We present here a new immunoblotting method, which is characterized by…”
Get full text

Titration of trace amounts of immunoglobulins in a microarray-based assay with magnetic labels by Shlyapnikov, Yuri M., Morozov, Victor N.

“…The existing immunoassay format that combines the electrophoretic collection of charged analytes on an antibody microarray with the detection of the bound…”
Get full text

Cancer-Retina Antigens in the Urine of Bladder and Prostate Cancer Patients by Shlyapnikov, Yuri M., Malakhova, Ekaterina A., Vinarov, Andrey Z., Potoldykova, Natalia V., Vladimirov, Vasiliy I., Zernii, Evgeni Yu, Zamyatnin, Andrey A., Shlyapnikova, Elena A.

“…It has recently been shown that combination of arrestin and recoverin can serve as an effective urinary biomarker for renal cell carcinoma with sensitivity and…”
Get full text

Ballistic Penetration of Highly Charged Nanoaerosol Particles through a Lipid Monolayer by Morozov, Victor N, Shlyapnikov, Yuri M, Kanev, Igor L, Shlyapnikova, Elena A

“…To be used as a drug, inhaled nanoaerosol particles (NAPs) must first penetrate the lipid layer on top of the lung fluid before they will be able to reach the…”
Get full text

Non-Invasive Diagnostics of Renal Cell Carcinoma Using Ultrasensitive Immunodetection of Cancer-Retina Antigens by Shlyapnikov, Yuri M., Malakhova, Ekaterina A., Potoldykova, Natalia V., Svetocheva, Yana A., Vinarov, Andrei Z., Zinchenko, Dmitry V., Zernii, Evgeni Yu, Zamyatnin, Andrey A., Shlyapnikova, Elena A.

“…Renal cell carcinoma (RCC) is the most common urological malignancy with a high mortality and low detection rate. One of the approaches to improving its…”
Get full text

Carboxymethyl Cellulose Film as a Substrate for Microarray Fabrication by Shlyapnikov, Yuri M, Shlyapnikova, Elena A, Morozov, Victor N

“…Magnetic beads (MB) are widely used for quick and highly sensitive signal detection in microarray-based assays. However, this technique imposes stringent…”
Get full text

Are Reactive Oxygen Species Generated in Electrospray at Low Currents? by Kanev, Igor L, Mikheev, Andrei Y, Shlyapnikov, Yuri M, Shlyapnikova, Elena A, Morozova, Tamara Y, Morozov, Victor N

“…It was demonstrated that electrospraying (ES) of solvents from a glass capillary proceeds without emission of light provided that the current is kept below a…”
Get full text

Rapid Generation of Neurospheres from Hippocampal Neurons Using Extracellular-Matrix-Mimetic Scaffolds by Antonova, Olga Y, Kochetkova, Olga Y, Kanev, Igor L, Shlyapnikova, Elena A, Shlyapnikov, Yuri M

“…3D models of brain organoids represent an innovative and promising tool in neuroscience studies. However, the process of neurosphere formation in vitro remains…”
Get full text

Rapid Simultaneous Ultrasensitive Immunodetection of Five Bacterial Toxins by Shlyapnikov, Yuri M, Shlyapnikova, Elena A, Simonova, Maria A, Shepelyakovskaya, Anna O, Brovko, Fedor A, Komaleva, Ravilya L, Grishin, Eugene V, Morozov, Victor N

“…Rapid ultrasensitive detection of gastrointestinal pathogens presents a great interest for medical diagnostics and epidemiologic services. Though conventional…”
Get full text

Filtering and optical properties of free standing electrospun nanomats from nylon-4,6 by Mikheev, Andrei Y., Shlyapnikov, Yuri M., Kanev, Igor L., Avseenko, Andrei V., Morozov, Victor N.

“…[Display omitted] •Free standing nanomats were fabricated from electrospun ultra-thin nylon-4,6 fibers.•The nanomats are optically transparent and…”
Get full text

Non-invasive lung disease diagnostics from exhaled microdroplets of lung fluid: perspectives and technical challenges by Morozov, Victor N, Mikheev, Andrey Y, Shlyapnikov, Yuri M, Nikolaev, Alexander A, Lyadova, Irina V

“…The combination of ultra-sensitive assay techniques and recent improvements in the instrumentation used to collect microdroplets of lung fluid (MLF) from…”
Get more information

Conic Electrophoretic Concentrator for Charged Macromolecules by Morozov, Victor N, Shlyapnikov, Yuri M, Kidd, Jessica, Morozova, Tamara Y, Shlyapnikova, Elena A

“…A simple, rapid, and highly effective technique for concentrating charged macromolecules is described which employs electrophoresis in a conic cell made of a…”
Get full text