Search Results - "SHIVAPURKAR, N"

DNA methylation based biomarkers in non-invasive cancer screening by Shivapurkar, N, Gazdar, A F

“…DNA methylation plays a critical role in the regulation of gene expression, differentiation and in the development of cancer and other diseases…”
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Decrease in blood miR-296 predicts chemotherapy resistance and poor clinical outcome in patients receiving systemic chemotherapy for metastatic colon cancer by Shivapurkar, N., Mikhail, S., Navarro, R., Bai, W., Marshall, J., Hwang, J., Pishvaian, M., Wellstein, A., He, A. R.

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Aberrant methylation of SPARC in human lung cancers by SUZUKI, M, HAO, C, TAKAHASHI, T, SHIGEMATSU, H, SHIVAPURKAR, N, SATHYANARAYANA, U. G, IIZASA, T, FUJISAWA, T, HIROSHIMA, K, GAZDAR, A. F

“…SPARC (secreted protein acidic and rich in cysteine) is an extracellular Ca2+-binding matricellular glycoprotein associated with the regulation of cell…”
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DNA methylation-associated inactivation of TGFβ-related genes, DRM/Gremlin, RUNX3, and HPP1 in human cancers by Suzuki, M, Shigematsu, H, Shames, D S, Sunaga, N, Takahashi, T, Shivapurkar, N, Iizasa, T, Frenkel, E P, Minna, J D, Fujisawa, T, Gazdar, A F

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DNA methylation-associated inactivation of TGFβ-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers by Suzuki, M, Shigematsu, H, Shames, D S, Sunaga, N, Takahashi, T, Shivapurkar, N, Iizasa, T, Frenkel, E P, Minna, J D, Fujisawa, T, Gazdar, A F

“…The transforming growth factor beta (TGF beta )-signalling pathway is deregulated in many cancers. We examined the role of gene silencing via aberrant…”
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Aberrant methylation of SPARC in human lung cancers by Suzuki, M, Hao, C, Takahashi, T, Shigematsu, H, Shivapurkar, N, Sathyanarayana, U G, Iizasa, T, Fujisawa, T, Hiroshima, K, Gazdar, A F

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Presence of simian virus 40 DNA sequences in human lymphoid and hematopoietic malignancies and their relationship to aberrant promoter methylation of multiple genes by SHIVAPURKAR, Narayan, TAKAHASHI, Takao, KROFT, Steven H, TIMMONS, Charles, MCKENNA, Robert W, ZIDING FENG, GAZDAR, Adi F, REDDY, Jyotsna, YINGYE ZHENG, STASTNY, Victor, COLLINS, Robert, TOYOOKA, Shinichi, SUZUKI, Makato, PARIKH, Gunjan, ASPLUND, Sheryl

“…The simian polyoma virus SV40 has been detected in specific human tumors including non-Hodgkin's lymphomas, although a causative role for the virus has not…”
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K-ras and p53 mutations in aberrant crypt foci and colonic tumors from colon cancer patients by Shivapurkar, N., Huang, L., Ruggeri, B., Swalsky, P.A., Bakker, A., Finkelstein, S., Frost, A., Silverberg, S.

“…Aberrant crypt foci (ACF) are microscopic lesions which can be detected, after methylene blue staining, in the overtly normal looking colonic mucosa of cancer…”
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Loss of Heterozygosity in Benign Breast Epithelium in Relation to Breast Cancer Risk by Euhus, David M., Cler, Leslie, Shivapurkar, Narayan, Milchgrub, Sara, Peters, George N., Leitch, A. Marilyn, Heda, Shashank, Gazdar, Adi F.

“…The multistage model of breast carcinogenesis suggests that errors in DNA replication and repair generate diversity in the breast epithelium (the mutator…”
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Inhibition by wheat bran cereals of the development of aberrant crypt foci and colon tumours by Alabaster, O., Tang, Z., Shivapurkar, N.

“…As variation in both type of fibre and its physical properties can influence physiological effects, the efects of different dietary levels (1, 4, 8%, w/w) of…”
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Inhibition of progression of aberrant crypt foci and colon tumor development by vitamin E and β-carotene in rats on a high-risk diet by Shivapurkar, Narayan, Tang, Zhaocheng, Frost, Andra, Alabaster, Oliver

“…In this study we evaluated the effect of dietary administration of a high-fat, low-fiber diet (HRD) supplemented with Vitamin E, β-carotene or folic acid and…”
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Potential synergism between wheat bran and psyllium: enhanced inhibition of colon cancer by Alabaster, O, Tang, Z C, Frost, A, Shivapurkar, N

“…In this study we compared the influence of high fat (20% w/w) diets that combine low levels of calcium (0.18% w/w) and low (1% w/w), medium (4% w/w) and high…”
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Genomic alterations in cultured human embryonic stem cells by Rao, Mahendra, Chakravarti, Aravinda, Maitra, Anirban, Arking, Dan E, Shivapurkar, Narayan, Ikeda, Morna, Stastny, Victor, Kassauei, Keyaunoosh, Sui, Guoping, Cutler, David J, Liu, Ying, Brimble, Sandii N, Noaksson, Karin, Hyllner, Johan, Schulz, Thomas C, Zeng, Xianmin, Freed, William J, Crook, Jeremy, Abraham, Suman, Colman, Alan, Sartipy, Peter, Matsui, Sei-Ichi, Carpenter, Melissa, Gazdar, Adi F

“…Cultured human embryonic stem cell (hESC) lines are an invaluable resource because they provide a uniform and stable genetic system for functional analyses and…”
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Hypomethylation of hepatic nuclear DNA in rats fed with a carcinogenic methyl-deficient diet by Wilson, M.J, Shivapurkar, N, Poirier, L.A

“…A progressive decrease was observed in the 5-methyldeoxycytidine content of hepatic DNA in male F344 rats fed with a hepatocarcinogenic methyl-deficient diet…”
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Apoptosis and lung cancer: A review by Shivapurkar, Narayan, Reddy, Jyotsna, Chaudhary, Preet M., Gazdar, Adi F.

“…It is important to understand the molecular events that contribute to drug‐induced apoptosis, and how tumors evade apoptotic death. Defects in apoptosis are…”
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Inhibition of aflatoxin B1 mutagenesis in Salmonella typhimurium and DNA damage in cultured rat and human tracheobronchial tissues by ellagic acid by Mandal, S, Ahuja, A, Shivapurkar, N M, Cheng, S J, Groopman, J D, Stoner, G D

“…Ellagic acid (EA), a plant phenol found in various fruits and nuts, was examined for its ability to inhibit aflatoxin B1 (AFB1) mutagenesis in strain TA 100 of…”
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Inhibition of N-nitrosobenzylmethylamine metabolism and DNA binding in cultured rat esophagus by ellagic acid by Mandal, S, Shivapurkar, N M, Galati, A J, Stoner, G D

“…The effect of ellagic acid (EA), a naturally occurring plant phenol, on the metabolism, DNA binding and DNA adduct formation of N-nitrosobenzylmethylamine…”
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Retraction Note: Aberrant methylation profile of human malignant mesotheliomas and its relationship to SV40 infection by Suzuki, M, Toyooka, S, Shivapurkar, N, Shigematsu, H, Miyajima, K, Takahashi, T, Stastny, V, Zern, A L, Fujisawa, T, Pass, H I, Carbone, M, Gazdar, A F

“…This paper is retracted due to image duplication involving scientific misconduct. The Internal Review Committee at UT Southwestern Medical Center, Dallas has…”
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DNA methylation-associated inactivation of TGF[beta]-related genes, DRM/Gremlin, RUNX3, and HPP1 in human cancers by Suzuki, M, Shigematsu, H, Shames, D S, Sunaga, N, Takahashi, T, Shivapurkar, N, Iizasa, T, Frenkel, E P, Minna, J D, Fujisawa, T, Gazdar, A F

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Retraction Note: DNA methylation-associated inactivation of TGFβ-related genes, DRM/Gremlin, RUNX3, and HPP1 in human cancers by Suzuki, M, Shigematsu, H, Shames, D S, Sunaga, N, Takahashi, T, Shivapurkar, N, Iizasa, T, Frenkel, E P, Minna, J D, Fujisawa, T, Gazdar, A F

“…An Internal Review Committee at UT Southwestern Medical Center found evidence of improper manipulation and replication of figures in this paper. A subsequent…”
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