Search Results - "SHIRAISHI, Mitsuya"

Novel Cytochrome P450 2C94 Functionally Metabolizes Diclofenac and Omeprazole in Dogs by Uno, Yasuhiro, Morikuni, Saho, Shiraishi, Mitsuya, Asano, Atsushi, Murayama, Norie, Yamazaki, Hiroshi

“…Cytochromes P450 (P450s or CYPs) are important drug-metabolizing enzymes. Because dogs are frequently used in drug metabolism studies, knowledge of dog CYP2C…”
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A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate promotes neuronal differentiation in SH-SY5Y human neuroblastoma cells by FERDOUS, Jannatul, NAITOU, Kiyotada, SHIRAISHI, Mitsuya

“…Myristoylated alanine-rich protein kinase C substrate (MARCKS) plays crucial roles in neuronal functions and differentiation. However, specific effects of the…”
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Measurement of canine blood microparticles by flow cytometry: effect of anticoagulants and staining reagents by OZAWA, Tsuyoshi, IJICHI, Takashi, SHIRAISHI, Mitsuya

“…Microparticles (MPs) are released from budding plasma membranes into body fluids. The use of flow cytometry for the measurement of MP in canines has not been…”
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A comprehensive analysis of six forms of cytochrome P450 2C (CYP2C) in pigs by Uno, Yasuhiro, Morikuni, Saho, Shiraishi, Mitsuya, Asano, Atsushi, Kawaguchi, Hiroaki, Murayama, Norie, Yamazaki, Hiroshi

“…Pigs are an important species used in drug metabolism studies; however, the cytochromes P450 (P450s or CYPs) have not been fully investigated in pigs. In this…”
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Involvement of beta3-adrenergic receptors in relaxation mediated by nitric oxide in chicken basilar artery by Wu, Siyuan, Ootawa, Tomoki, Sekio, Ryoya, Smith, Henry, Islam, Md. Zahorul, Uno, Yasuhiro, Shiraishi, Mitsuya, Miyamoto, Atsushi

“…The response of basilar arteries to noradrenaline varies among many animal species, but remains little studied in poultry. Accordingly, we aimed to…”
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Molecular and Functional Characterization of N -Acetyltransferases in Common Marmosets and Pigs by Uno, Yasuhiro, Uehara, Shotaro, Ijiri, Moe, Kawaguchi, Hiroaki, Asano, Atsushi, Shiraishi, Mitsuya, Banju, Kaito, Murayama, Norie, Yamazaki, Hiroshi

“…Arylamine -acetyltransferases (NATs) are drug-metabolizing enzymes that are essential for the metabolism of endogenous substrates and xenobiotics. The…”
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Comparative analysis of in vitro neurotoxicity of methylmercury, mercury, cadmium, and hydrogen peroxide on SH-SY5Y cells by SUDO, Kasumi, DAO, Cuong VAN, MIYAMOTO, Atsushi, SHIRAISHI, Mitsuya

“…Mercury (Hg) and cadmium (Cd) are the major toxic heavy metals and are known to induce neurotoxicity. Although many studies have shown that several heavy…”
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α-MSH-induced activation of spinal MC1R but not MC4R enhances colorectal motility in anaesthetised rats by Ueda, Hiromi H., Naitou, Kiyotada, Nakamori, Hiroyuki, Horii, Kazuhiro, Shiina, Takahiko, Masatani, Tatsunori, Shiraishi, Mitsuya, Shimizu, Yasutake

“…The central nervous system is involved in regulation of defaecation. It is generally considered that supraspinal regions control the spinal defaecation centre…”
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Direct evidence of nitric oxide production induced by lactoferrin and its enhancement by magnesium ions in cultured endothelial cells by NII, Tomoaki, ISLAM, Md Zahorul, KAKE, Satoru, SHIRAISHI, Mitsuya, TAKEUCHI, Takashi, KUWATA, Hidefumi, MIYAMOTO, Atsushi, HARADA, Etsumori

“…Bovine lactoferrin (BLF) reportedly lowers blood pressure and induces vasorelaxation, but its effect on nitric oxide (NO) production has not been established…”
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Vasomotor effects of noradrenaline, 5-hydroxytryptamine, angiotensin II, bradykinin, histamine, and acetylcholine on the bat (Rhinolophus ferrumequinum) basilar artery by Islam, Md. Zahorul, Kojima, Shusuke, Sameshima, Masamichi, Obi, Takeshi, Yamazaki-Himeno, Emi, Shiraishi, Mitsuya, Miyamoto, Atsushi

“…The responsiveness of the basilar artery to intrinsic vasoactive substances is species-specific and can be a unique characteristic. We investigated the…”
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Heavy metal chelator TPEN attenuates fura-2 fluorescence changes induced by cadmium, mercury and methylmercury by OHKUBO, Masato, MIYAMOTO, Atsushi, SHIRAISHI, Mitsuya

“…Stimulation with heavy metals is known to induce calcium (Ca2+) mobilization in many cell types. Interference with the measurement of intracellular Ca2+…”
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Habu snakes (Protobothrops flavoviridis) show variation in thoracic aortic vasoreactivity between adjacent Japanese islands by OOTAWA, Tomoki, WU, Siyuan, SEKIO, Ryoya, SMITH, Henry, ISLAM, Md Zahorul, NGUYEN, Ha Thi Thanh, UNO, Yasuhiro, SHIRAISHI, Mitsuya, MIYAMOTO, Atsushi

“…Habu snakes (Protobothrops flavoviridis) are pit vipers found in the geographically adjacent but ecologically divergent islands of Tokunoshima and Amami-Oshima…”
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Relationship between Regional Distribution of Centenarians and Drinking Water Hardness in the Amami Islands, Kagoshima Prefecture, Japan by Suzuki, Mai, Wu, Siyuan, Ootawa, Tomoki, Smith, Henry, Shiraishi, Mitsuya, Miyamoto, Atsushi, Matsuoka, Yuki, Sawa, Sawako, Mori, Mari, Mori, Hideki, Yamori, Yukio

“…People who drink naturally hardened water may experience longevity-enhancing effects. In this study, we investigated water hardness and longevity from both…”
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Methylmercury affects cerebrovascular reactivity to angiotensin II and acetylcholine via Rho-kinase and nitric oxide pathways in mice by Islam, Md. Zahorul, Van Dao, Cuong, Shiraishi, Mitsuya, Miyamoto, Atsushi

“…Methylmercury (MeHg) exposure results in increased risk of hypertension and cardiovascular diseases. In this study, we aimed to investigate whether the in vivo…”
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Vasomotor effects of 5-hydroxytryptamine, histamine, angiotensin II, acetylcholine, noradrenaline, and bradykinin on the cerebral artery of bottlenose dolphin (Tursiops truncatus) by ISLAM, Md. Zahorul, SAWATARI, Yuji, KOJIMA, Shusuke, KIYAMA, Yusuke, NAKAMURA, Moe, SASAKI, Kyouko, OTSUKA, Mika, OBI, Takeshi, SHIRAISHI, Mitsuya, MIYAMOTO, Atsushi

“…From an evolutionary aspect, dolphins share a very close phylogenetic relationship with pigs. Previously, we characterized porcine cerebral artery…”
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Rho-kinase and the nitric oxide pathway modulate basilar arterial reactivity to acetylcholine and angiotensin II in streptozotocin-induced diabetic mice by Islam, Md. Zahorul, Van Dao, Cuong, Miyamoto, Atsushi, Shiraishi, Mitsuya

“…Diabetes mellitus comprises a heterogeneous group of metabolic disorders with underlying hyperglycemia and secondary cardiovascular complications. Growing…”
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The MARCKS protein amount is differently regulated by calpain during toxic effects of methylmercury between SH-SY5Y and EA.hy926 cells by DAO, Cuong Van, SHIRAISHI, Mitsuya, MIYAMOTO, Atsushi

“…Methylmercury (MeHg) is an environmental pollutant that shows severe toxicity to humans and animals. However, the molecular mechanisms mediating MeHg toxicity…”
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Characterization of Vasoreactivity in a Semi-Arboreal Snake, the Tokara Habu ( Protobothrops tokarensis ) by Ootawa, Tomoki, Wu, Siyuan, Sekio, Ryoya, Smith, Henry, Islam, Md Zahorul, Nguyen, Ha Thi Thanh, Uno, Yasuhiro, Shiraishi, Mitsuya, Miyamoto, Atsushi

“…Vasoreactivity is relatively well documented in terrestrial snakes but has previously been investigated in only one semi-arboreal snake species. Consequently,…”
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A highly sensitive technique to measure myosin regulatory light chain phosphorylation: the first quantification in renal arterioles by Takeya, Kosuke, Loutzenhiser, Kathy, Shiraishi, Mitsuya, Loutzenhiser, Rodger, Walsh, Michael P

“…Phosphorylation of the 20-kDa myosin regulatory light chains (LC(20)) plays a key role in the regulation of smooth muscle contraction. The level of LC(20)…”
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Reduced Nitric Oxide Synthase Involvement in Aigamo Duck Basilar Arterial Relaxation by Wu, Siyuan, Ootawa, Tomoki, Sekio, Ryoya, Smith, Henry, Islam, Md. Zahorul, Nguyen, Ha Thi Thanh, Uno, Yasuhiro, Shiraishi, Mitsuya, Miyamoto, Atsushi

“…The basilar arterial endothelium mediates blood vessel relaxation partly through the release of nitric oxide (NO). Apoptosis of cerebrovascular endothelial…”
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