Search Results - "SHINDO, Takashi"

SUR2 subtype (A and B)‐dependent differential activation of the cloned ATP‐sensitive K+ channels by pinacidil and nicorandil by Shindo, Takashi, Yamada, Mitsuhiko, Isomoto, Shojiro, Horio, Yoshiyuki, Kurachi, Yoshihisa

“…The classical ATP sensitive K+ (KATP) channels are composed of a sulphonylurea receptor (SUR) and an inward rectifying K+ channel subunit (BIR/Kir6.2). They…”
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Effects of 5-fluorouracil on the drug-metabolizing enzymes of the small intestine and the consequent drug interaction with nifedipine in rats by Yoshisue, K, Nagayama, S, Shindo, T, Kawaguchi, Y

“…5-Fluorouracil (5-FU) is a widely used antineoplastic agent. 5-FU therapy often causes gastrointestinal toxicity, which is suppressed by concomitant…”
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Gadopentetate Dimeglumine as a Potential Alternative Contrast Medium During Percutaneous Coronary Intervention: A Case Report by Furuichi, Shinichi, Yasuda, Satoshi, Arita, Yukio, Miyawaki, Masami, Nomura, Kei, Nonogi, Hiroshi, Shindo, Takashi

“…Background There have not been previous reports of patients undergoing percutaneous coronary intervention (PCI) using a gadolinium chelate. Methods and Results…”
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Progression of coronary atherosclerosis: Is coronary spasm related to progression? by Nobuyoshi, Masakiyo, Tanaka, Makoto, Nosaka, Hideyuki, Kimura, Takeshi, Yokoi, Hiroatsu, Hamasaki, Naoya, Kim, Kotaku, Shindo, Takashi, Kimura, Kazuo

“…A total of 239 patients undergoing serial coronary angiography with a concomitant ergonovine provocation test were studied between July 1974 and June 1987. The…”
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The effects of nucleotides and potassium channel openers on the SUR2A/Kir6.2 complex K+ channel expressed in a mammalian cell line, HEK293T cells by Okuyama, Y, Yamada, M, Kondo, C, Satoh, E, Isomoto, S, Shindo, T, Horio, Y, Kitakaze, M, Hori, M, Kurachi, Y

“…The effects of potassium channel opening drugs and intracellular nucleotides on the ATP-sensitive K+ (KATP) channel composed of SUR2A and Kir6.2 in HEK293T…”
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DISTRIBUTION OF (7α)-21-[4-[(DIETHYLAMINO) METHYL]-2-METHOXYPHENOXY]-7-METHYL-19-NORPREGNA-1,3,5(10)-TRIEN-3-OL-20-[14C]2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE ([14C]TAS-108) AND ITS METABOLITES AFTER SINGLE ORAL ADMINISTRATION TO RATS BEARING 7,12-DIMETHYLBENZ(α)ANTHRACENE-INDUCED MAMMARY TUMOR by YAMAYA, Hidetoshi, SAEKI, Mayuko, YOSHIDA, Ken-Ichiro, SHIBATA, Jiro, YANO, Shingo, SATO, Yoshiaki, TAKAO, Atsushi, SHINDO, Takashi, BUZDAR, Aman U, NAGAYAMA, Sekio

“…(7α)-21-[4-[(Diethylamino)methyl]-2-methoxyphenoxy]-7-methyl-19-norpregna-1,3,5(10)-trien-3-ol 2-hydroxy-1,2,3-propanetricarboxylate (TAS-108) is a novel…”
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Intraoperative Identification of the Shunt Point of Spinal Arteriovenous Malformations by a Selective Arterial Injection of Saline to Subtract Signals of Indocyanine Green: Technical Note by Takamiya, Soichiro, Yamazaki, Kazuyoshi, Tokairin, Kikutaro, Osanai, Toshiya, Shindo, Takashi, Seki, Toshitaka, Fujimura, Miki

“…It is crucial to identify a shunt point for spinal arteriovenous malformation (AVM) treatment. For this purpose, some intraoperative supports have been…”
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MCC-134, a novel vascular relaxing agent, is an inverse agonist for the pancreatic-type ATP-sensitive K(+) channel by Shindo, T, Katayama, Y, Horio, Y, Kurachi, Y

“…The effects of a novel vasorelaxant agent, MCC-134 (1-[4-(1H-imidazol-1-yl)benzoyl]-N-methyl-cyclobutanecarbothioamide++ +), were examined on reconstituted…”
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Statistical analysis of clinical risk factors for coronary artery spasm: identification of the most important determinant by Nobuyoshi, M, Abe, M, Nosaka, H, Kimura, T, Yokoi, H, Hamasaki, N, Shindo, T, Kimura, K, Nakamura, T, Nakagawa, Y

“…Coronary artery spasm plays an important role in acute ischemic events, and it has a close relationship with coronary atherosclerosis. Thus we attempted to…”
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Synthesis, biological active molecular design, and molecular docking study of novel deazaflavin–cholestane hybrid compounds by Shrestha, Ajaya R., Shindo, Takashi, Ashida, Noriyuki, Nagamatsu, Tomohisa

“…Novel deazaflavin–cholestane hybrid compounds, 3′,8′-disubstituted-5′-deazacholest-2,4-dieno[2,3- g]pteridine-2′,4′(3′ H,8′ H)-diones, have been synthesized by…”
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Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel by Yamada, M, Isomoto, S, Matsumoto, S, Kondo, C, Shindo, T, Horio, Y, Kurachi, Y

“…1. We analysed the K+ channel composed of the sulphonylurea receptor 2B (SUR2B) and an inwardly rectifying K+ channel subunit Kir6.1 coexpressed in a mammalian…”
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Clearance and tissue distribution of functionalized polymeric liposomes from the blood stream of rats by Matsushita, Y, Eshima, K, Shindo, T, Yamamoto, Y, Hasegawa, E, Nishide, H, Tsuchida, E

“…Polymeric liposomes containing a synthetic porphinato-iron-imidazole complex (hemoglobin or red blood cell model) were labeled by introducing…”
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Pharmacokinetic Studies on Propiverine Hydrochloride‐Metabolites in Urinary Bladder, Other Tissues and Urine of Rats by YAMAMOTO, Yoshio, TSUDA, Masuhiro, UDA, Kazuhiko, MATSUSHITA, Hitoshi, SHINDO, Takashi, KAWAGUCHI, Yasuro

“…The concentrations of the metabolites of propiverine hydrochloride (1-methyl-4 piperidyl diphenylpropoxyacetate hydrochloride, abbreviated as P-4) in rat…”
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MCC-134, a novel vascular relaxing agent, is an inverse agonist for the pancreatic type of ATP-sensitive K+ channel by Shindo, Takashi, Katayama, Yusuke, Horio, Yoshiyuki, Kurachi, Yoshihisa

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Ultrasound attenuated coronary plaque as a risk factor for slow flow or no-reflow during percutaneous coronary intervention: a case report by Furuichi, Shinichi, Itoh, Akira, Ishibashi-Ueda, Hatsue, Noguchi, Teruo, Miyawaki, Masami, Nomura, Kei, Arita, Yukio, Otsuka, Masato, Shindo, Takashi

“…Slow flow or no-reflow is a serious complication during percutaneous coronary intervention (PCI), but little is known about the risk factors. A 64-year-old man…”
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Pharmacokinetic Studies of Suplatast tosilate (IPD-1151T). (II): Identification of Metabolites and Metabolism in Rats after Oral Administration of 14C-Suplatast tosilate (IPD-1151T) to Rats by MASUDA, Hirotoshi, KUWATA, Keizo, MATSUSHIMA, Eiji, YAMAWAKI, Ichiro, SHINDO, Takashi

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Pharmacokinetic Studies of Suplatast tosilate(IPD-1151T). (IV). Dose dependency and sex difference of Suplatast tosilate(IPD-1151T) in Rats by KUWATA, Keizo, MASUDA, Hirotoshi, SATO, Toshiyuki, SHINDO, Takashi

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Pharmacokinetic Studies of 6-amidino-2-naphthyl 4-((4,5-dihydro-1H-imidazol-2-yl)amino)benzoate dimethanesulfonate (FUT-187). (V). Absorption, Distribution, Metabolism and Excretion in Dogs by TSUDA, Masuhiro, YAMAMOTO, Yoshio, SHINDO, Takashi, KAWAGUCHI, Yasuro, KOMATSU, Shinzo

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Pharmacokinetic studies of Suplatast tosilate (IPD-1151T). (III): Species differences of Suplatast tosilate (IPD-1151T) and its metabolic pathways by SHINDO, Takashi, MASUDA, Hirotoshi, KUWATA, Keizo, YAMAMOTO, Yoshio, SATO, Toshiyuki

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Pharmacokinetic Studies of Propiverine hydrochloride. (5): Animal differences in vivo, in vitro and protein binding by TSUDA, Masuhiro, YAMAMOTO, Yoshio, UDA, Kazuhiko, SHINDO, Takashi, KAWAGUCHI, Yasuro

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