Search Results - "SHINAGAWA, Atsushi"

Ixazomib-induced Sweet’s syndrome by Suyama, Takuya, Ito, Syusaku, Shinagawa, Atsushi

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Pomalidomide‐bortezomib‐dexamethasone in relapsed or refractory multiple myeloma: Japanese subset analysis of OPTIMISMM by Sunami, Kazutaka, Matsue, Kosei, Suzuki, Kenshi, Takezako, Naoki, Shinagawa, Atsushi, Sakurai, Sanae, Tamakoshi, Hiromi, Biyukov, Tsvetan, Peluso, Teresa, Richardson, Paul

“…In the phase 3 OPTIMISMM trial, pomalidomide, bortezomib and dexamethasone (PVd) significantly improved the progression‐free survival (PFS) and the overall…”
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Venetoclax plus low-dose cytarabine in patients with newly diagnosed acute myeloid leukemia ineligible for intensive chemotherapy: an expanded access study in Japan by Asada, Noboru, Ando, Jun, Takada, Satoru, Yoshida, Chikashi, Usuki, Kensuke, Shinagawa, Atsushi, Ishizawa, Kenichi, Miyamoto, Toshihiro, Iida, Hiroatsu, Dobashi, Nobuaki, Okubo, Sumiko, Honda, Hideyuki, Soshin, Tomomi, Nishimura, Yasuko, Tsutsui, Atsuko, Mukai, Harumi, Yamamoto, Kazuhito

“…Abstract Background In a Phase 3 international clinical trial (VIALE-C), venetoclax plus low-dose cytarabine improved the response rate and overall survival…”
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Venetoclax plus azacitidine in Japanese patients with untreated acute myeloid leukemia ineligible for intensive chemotherapy by Yamamoto, Kazuhito, Shinagawa, Atsushi, DiNardo, Courtney D, Pratz, Keith W, Ishizawa, Kenichi, Miyamoto, Toshihiro, Komatsu, Norio, Nakashima, Yasuhiro, Yoshida, Chikashi, Fukuhara, Noriko, Usuki, Kensuke, Yamauchi, Takahiro, Asada, Noboru, Asou, Norio, Choi, Ilseung, Miyazaki, Yasushi, Honda, Hideyuki, Okubo, Sumiko, Kurokawa, Misaki, Zhou, Ying, Zha, Jiuhong, Potluri, Jalaja, Matsumura, Itaru

“…Abstract Background The phase 3 VIALE-A trial (NCT02993523) reported that venetoclax-azacitidine significantly prolonged overall survival compared with…”
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Safety and efficacy of daratumumab in combination with bortezomib and dexamethasone in Japanese patients with relapsed or refractory multiple myeloma by Iida, Shinsuke, Ichinohe, Tatsuo, Shinagawa, Atsushi, Suzuki, Kenshi, Takezako, Naoki, Aoki, Masayuki

“…Daratumumab in combination with bortezomib and dexamethasone (DVd) has demonstrated longer progression-free survival than combination of bortezomib and…”
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TCL1-family negative T-cell prolymphocytic leukemia with rapid progression of extranodal disease despite a normal white blood cell count by Shimizu, Misayo, Tsuboi, Yuri, Kuroda, Akihiro, Seki, Masanori, Shinagawa, Atsushi

“…Here we describe the case of a 69-year-old man who was found to have moderate thrombocytopenia and severe splenomegaly during a medical checkup at the age of…”
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FIP1L1::PDGFRA-positive chronic eosinophilic leukemia showing slowly progressive cardiac impairment by Shimizu, Misayo, Kuroda, Akihiro, Suyama, Takuya, Seki, Masanori, Shinagawa, Atsushi

“…This report describes a 69-year-old man with eosinophilia that was detected during a medical check-up. A review of his medical history revealed that his…”
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Female and preserved platelet count subgroups of myelodysplastic syndrome patients benefit from standard‐dose azacitidine by Ogawa, Shinichi, Sakamoto, Tatsuhiro, Matsuoka, Ryota, Ishitsuka, Kantaro, Ogino, Yasuko, Sootome, Ayano, Makishima, Kenichi, Yoshida, Chikashi, Ito, Yufu, Shimizu, Seiichi, Suyama, Takuya, Shinagawa, Atsushi, Ito, Takayoshi, Obara, Naoshi, Kusakabe, Manabu, Sakata‐Yanagimoto, Mamiko, Miyazaki, Yasushi, Nannya, Yasuhito, Chiba, Shigeru

“…Background Hypomethylating agents, including azacytidine (AZA), are standard therapeutics for patients with high‐risk myelodysplastic syndromes (MDS), a group…”
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Relative increase in lymphocytes from as early as 1 month predicts improved response to dasatinib in chronic-phase chronic myelogenous leukemia by Kumagai, Takashi, Matsuki, Eri, Inokuchi, Koiti, Ohashi, Kazuteru, Shinagawa, Atsushi, Takeuchi, Jin, Yoshida, Chikashi, Okamoto, Shinichiro, Wakita, Hisashi, Kozai, Yasuji, Shirasugi, Yukari, Fujisawa, Shin, Iwase, Osamu, Yano, Shingo, Nishiwaki, Kaichi, Oba, Koji, Sakamoto, Junichi, Sakamaki, Hisashi

“…Lymphocytosis in response to dasatinib for chronic myelogenous leukemia (CML) may be associated with favorable response. However, it occurs at varying times…”
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Lenalidomide and low‐dose dexamethasone in Japanese patients with newly diagnosed multiple myeloma: A phase II study by Suzuki, Kenshi, Shinagawa, Atsushi, Uchida, Toshiki, Taniwaki, Masafumi, Hirata, Hirokazu, Ishizawa, Kenichi, Matsue, Kosei, Ogawa, Yoshiaki, Shimizu, Takayuki, Otsuka, Maki, Matsumoto, Morio, Iida, Shinsuke, Terui, Yasuhito, Matsumura, Itaru, Ikeda, Takashi, Takezako, Naoki, Ogaki, Yumi, Midorikawa, Shuichi, Houck, Vanessa, Ervin‐Haynes, Annette, Chou, Takaaki

“…In the FIRST trial (MM‐020), lenalidomide plus low‐dose dexamethasone (Rd) reduced the risk of disease progression or death compared with combination…”
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Optimal treatment strategy with nilotinib for patients with newly diagnosed chronic‐phase chronic myeloid leukemia based on early achievement of deep molecular response (MR4.5): The phase 2, multicenter N‐Road study by Nishiwaki, Kaichi, Sugimoto, Kei‐ji, Tamaki, Shigehisa, Hisatake, Junichi, Yokoyama, Hisayuki, Igarashi, Tadahiko, Shinagawa, Atsushi, Sugawara, Takeaki, Hara, Satoru, Fujikawa, Kazuhisa, Shimizu, Seiichi, Yujiri, Toshiaki, Tojo, Arinobu, Wakita, Hisashi

“…For patients who have chronic myeloid leukemia (CML), one of the primary treatment options is administration of nilotinib 300 mg twice daily (BID). In previous…”
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Early dynamics of chronic myeloid leukemia on nilotinib predicts deep molecular response by Okamoto, Yuji, Hirano, Mitsuhito, Morino, Kai, Kajita, Masashi K., Nakaoka, Shinji, Tsuda, Mayuko, Sugimoto, Kei-ji, Tamaki, Shigehisa, Hisatake, Junichi, Yokoyama, Hisayuki, Igarashi, Tadahiko, Shinagawa, Atsushi, Sugawara, Takeaki, Hara, Satoru, Fujikawa, Kazuhisa, Shimizu, Seiichi, Yujiri, Toshiaki, Wakita, Hisashi, Nishiwaki, Kaichi, Tojo, Arinobu, Aihara, Kazuyuki

“…Chronic myeloid leukemia (CML) is a myeloproliferative disorder caused by the BCR-ABL1 tyrosine kinase. Although ABL1 -specific tyrosine kinase inhibitors…”
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Adherence to the standard dose of imatinib, rather than dose adjustment based on its plasma concentration, is critical to achieve a deep molecular response in patients with chronic myeloid leukemia by Yoshida, Chikashi, Komeno, Takuya, Hori, Mitsuo, Kimura, Tomofumi, Fujii, Masami, Okoshi, Yasushi, Suzukawa, Kazumi, Chiba, Shigeru, Hasegawa, Yuichi, Mukai, Harumi Yamamoto, Ito, Takayoshi, Shimizu, Seiichi, Kamoshita, Masaharu, Kudo, Daisuke, Shinagawa, Atsushi, Chikatsu, Norio, Monma, Yuriko, Watanabe, Norimichi, Kojima, Hiroshi

“…The correlation between imatinib (IM) trough plasma concentration (Cmin) and clinical response was assessed in patients with chronic-phase chronic myeloid…”
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Quantification of mRNA in Whole Blood by Assessing Recovery of RNA and Efficiency of cDNA Synthesis by Mitsuhashi, Masato, Tomozawa, Shigeru, Endo, Katsuya, Shinagawa, Atsushi

“…Current gene expression analysis relies on the assumption that the isolated RNA represents all species of mRNA in proportions equal to those in the original…”
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Durable Leukemic Remission and Autologous Marrow Recovery with Random Chromosomal Abnormalities after Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Lymphocytic Leukemia by Hasegawa, Yuichi, Nakamura, Naoya, Chiba, Shigeru, Sakata-Yanagimoto, Mamiko, Kato, Takayasu, Yokoyama, Yasuhisa, Kusakabe, Manabu, Sakamoto, Tatsuhiro, Shinagawa, Atsushi, Kurita, Naoki, Nishikii, Hidekazu, Obara, Naoshi

“…A 38-year-old woman with aggressive clinical course of chronic lymphocytic leukemia (CLL) was treated with 8 courses of R-CHOP. Clinical remission was…”
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Efficacy of Molecular Response at 1 or 3 Months after the Initiation of Dasatinib Treatment Can Predict an Improved Response to Dasatinib in Imatinib-Resistant or Imatinib-Intolerant Japanese Patients with Chronic Myelogenous Leukemia during the Chronic Phase by Inokuchi, Koiti, Kumagai, Takashi, Matsuki, Eri, Ohashi, Kazuteru, Shinagawa, Atsushi, Hatta, Yoshihiro, Takeuchi, Jin, Yoshida, Chikashi, Wakita, Hisashi, Kozai, Yasuji, Shirasugi, Yukari, Fujisawa, Shin, Iwase, Osamu, Yano, Shingo, Okamoto, Shinichiro, Oba, Koji, Sakamoto, Junichi, Sakamaki, Hisashi

“…Dasatinib is a BCR-ABL kinase inhibitor with improved potency compared with imatinib, for which efficacy and safety in imatinib-resistant and…”
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ALK+, CD30−, CD20− Large B-Cell Lymphoma Containing Anaplastic Lymphoma Kinase (ALK) Fused to Clathrin Heavy Chain Gene (CLTC) by Chikatsu, Norio, Kojima, Hiroshi, Suzukawa, Kazumi, Shinagawa, Atsushi, Nagasawa, Toshiro, Ozawa, Hiroaki, Yamashita, Yoriko, Mori, Naoyoshi

“…Pathological features and genomic basis of a rare case of ALK+, CD30−, CD20− large B-cell lymphoma were analyzed. A 36-year-old Japanese female was admitted…”
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Myelodysplastic syndrome with neutrophilic dermatosis successfully treated with azacitidine by Kudo, Daisuke, Shimizu, Misayo, Kuroda, Akihiro, Suyama, Takuya, Shinagawa, Atsushi, Ito, Syusaku

“…A 66-year-old male underwent prednisolone (PSL) therapy of 13 mg/day for rheumatoid arthritis (RA). Antiphospholipid antibody syndrome, neutrophilic dermatosis…”
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Ex Vivo Induction of mRNA in Human Whole Blood as a New Platform of Drug and Dietary Supplement Development by Mitsuhashi, Masato, Ogura, Mieko, Endo, Katsuya, Obara, Kazuhiko, Izutsu, Hiroshi, Targan, Stephan R., Maemura, Motoko, Tachikawa, Daisuke, Shinagawa, Atsushi

“…Purpose We introduced a new concept of ex vivo gene expression analysis (Mitsuhashi, Clin Chem 53:148–149, 2007), where drug action was simulated under…”
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A CASE OF GRANULOCYTIC SARCOMA IN THE BILATERAL URETER by Miyagawa, Tomoaki, Tanaka, Ken, Ikeda, Atsushi, Komine, Manabu, Tsutsumi, Masakazu, Shinagawa, Atsushi

“…A 61-year-old female presented with the complaints of fever and left back pain. She had previously undergone bone marrow transplantation for acute myeloid…”
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