Search Results - "SHIN, SOYOUNG"

Development of a gastroretentive delivery system for acyclovir by 3D printing technology and its in vivo pharmacokinetic evaluation in Beagle dogs by Shin, Soyoung, Kim, Tae Hwan, Jeong, Seok Won, Chung, Seung Eun, Lee, Da Young, Kim, Do-Hyung, Shin, Beom Soo

“…Gastroretentive (GR) systems are designed to prolong gastric residence time to allow sustained absorption and improve the oral bioavailability of drugs with a…”
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3D-Printed Gastroretentive Sustained Release Drug Delivery System by Applying Design of Experiment Approach by Jeong, Hyeon Myeong, Weon, Kwon-Yeon, Shin, Beom Soo, Shin, Soyoung

“…This study aimed to develop a novel oral drug delivery system for gastroretentive sustained drug release by using a capsular device. A capsular device that can…”
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Is HOXA5 a Novel Prognostic Biomarker for Uterine Corpus Endometrioid Adenocarcinoma? by Song, Changho, Kim, Kyoung Bo, Lee, Gi Su, Shin, Soyoung, Kim, Byoungje

“…Endometrial cancer (EC) is one of the most pervasive malignancies in females worldwide. HOXA5 is a member of the homeobox (HOX) family and encodes the HOXA5…”
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Minoxidil Promotes Hair Growth through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells by Choi, Nahyun, Shin, Soyoung, Song, Sun U, Sung, Jong-Hyuk

“…Minoxidil directly promotes hair growth via the stimulation of dermal papilla (DP) and epithelial cells. Alternatively, there is little evidence for indirect…”
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Novel modeling approach integrating population pharmacokinetics and interspecies scaling to predict human pharmacokinetics of the new anti-tuberculosis agent telacebec (Q203) by Kim, Jeongjun, Kim, Tae Hwan, Choi, Jinho, Nam, Kiyean, Shin, Beom Soo, Shin, Soyoung

“…Telacebec is a new anti-tuberculosis agent with promising therapeutic activity and a favorable safety profile. This study aimed to characterize the…”
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Pharmacokinetics of Nafamostat, a Potent Serine Protease Inhibitor, by a Novel LC-MS/MS Analysis by Oh, Hyeon Seok, Kim, Taehyung, Gu, Dong-Hyeon, Lee, Tae Suk, Kim, Tae Hwan, Shin, Soyoung, Shin, Beom Soo

“…Nafamostat, a synthetic serine protease inhibitor, has been used for the treatment of inflammatory diseases such as pancreatitis. Recently, an increasing…”
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Seizure duration may increase thyroid-stimulating hormone levels in children experiencing a seizure by Han, Ji Yoon, Lee, In Goo, Shin, Soyoung, Park, Joonhong

“…Objective Variations in hormone levels are a direct effect of epileptic discharges in both animals and humans, and seizure can affect the…”
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Determination of pharmacokinetics and tissue distribution of a novel lutetium-labeled PSMA-targeted ligand, 177Lu-DOTA-PSMA-GUL, in rats by using LC–MS/MS by Song, Chang Ho, Kim, Kweon, Kang, Eunhee, Jeong, Bora, Lee, Myung-Su, Jung, Jiyoon, Kim, Tae Hwan, Shin, Soyoung, Shin, Beom Soo

“…Prostate specific membrane antigen (PSMA) is known to be overexpressed in prostate cancer cells, providing as a diagnostic and therapeutic target for prostate…”
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Cellular interactions between L-arginine and asymmetric dimethylarginine: Transport and metabolism by Shin, Soyoung, Thapa, Subindra Kazi, Fung, Ho-Leung

“…This study was aimed to examine the effect of L-arginine (ARG) exposure on the disposition of asymmetric dimethylarginine (ADMA) in human endothelial cells…”
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The impact of enhanced screening for carbapenemase-producing Enterobacterales in an acute care hospital in South Korea by Park, Sun Hee, Yi, Yunmi, Suh, Woosuck, Ji, Seul Ki, Han, Eunhee, Shin, Soyoung

“…Carbapenemase-producing Enterobacterales (CPE) poses a significant challenge to infection control in healthcare settings. Active screening is recommended to…”
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Comprehensive assessment of SARS-CoV-2 antibodies against various antigenic epitopes after naive COVID-19 infection and vaccination (BNT162b2 or ChAdOx1 nCoV-19) by Lee, Jihyun, Lee, Dong-Gun, Jung, Jin, Ryu, Ji Hyeong, Shin, Soyoung, Cho, Sung-Yeon, Lee, Raeseok, Oh, Eun-Jee

“…Comprehensive assessment of SARS-CoV-2 antibodies against antigenic epitopes and cross-neutralization on variants is essential to monitor after infection or…”
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Combined mandibular inverted L osteotomy and total mandibular subapical osteotomy by Fisher, Anson Grant, Johnson, Jacob, Shin, Soyoung, Yim, Chang Min Richard

“…This case report documents a patient with a Class II skeletal malocclusion and suspected obstructive sleep apnea who underwent a combined mandibular inverted L…”
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The impact of the Xpert MTB/RIF screening among hospitalized patients with pneumonia on timely isolation of patients with pulmonary tuberculosis by Han, Seung Beom, Park, Joonhong, Ji, Seul Ki, Jang, So Hee, Shin, Soyoung, Kim, Myung Sook, Kim, Seung Soo, Park, Sun Hee

“…In South Korea where the tuberculosis (TB) burden is intermediate, the risk of in-hospital transmission of TB remains high. We conducted a retrospective cohort…”
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Establishment of Level a In Vitro–In Vivo Correlation (IVIVC) via Extended DoE-IVIVC Model: A Donepezil Case Study by Lee, Da Young, Shin, Soyoung, Kim, Tae Hwan, Shin, Beom Soo

“…This study aimed to establish an extended design of experiment (DoE)-in vitro in vivo correlation (IVIVC) model that defines the relationship between…”
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Liquid Chromatography-Tandem Mass Spectrometry of Desoxo-Narchinol a and Its Pharmacokinetics and Oral Bioavailability in Rats and Mice by Thapa, Subindra Kazi, Upadhyay, Mahesh, Kim, Tae Hwan, Shin, Soyoung, Park, Sung-Joo, Shin, Beom Soo

“…Desoxo-narchinol A is one of the major active constituents from , which has been reported to possess various pharmacological activities, including…”
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Effects of Phytochemical P-Glycoprotein Modulators on the Pharmacokinetics and Tissue Distribution of Doxorubicin in Mice by Kim, Tae Hwan, Shin, Soyoung, Yoo, Sun Dong, Shin, Beom Soo

“…Pungent spice constituents such as piperine, capsaicin and [6]-gingerol consumed via daily diet or traditional Chinese medicine, have been reported to possess…”
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Liquid Chromatography-Tandem Mass Spectrometry Analysis of Riboflavin in Beagle Dog Plasma for Pharmacokinetic Studies by Hyeon Myeong Jeong, Beom Soo Shin, Soyoung Shin

“…Riboflavin is a water-soluble vitamin, which serves as a precursor to flavin mononucleotide and flavin adenine dinu-cleotide. This study aimed to develop a…”
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Simultaneous bioanalysis of l-arginine, l-citrulline, and dimethylarginines by LC–MS/MS by Shin, Soyoung, Fung, Sun-Mi, Mohan, Srinidi, Fung, Ho-Leung

“…l-Arginine (ARG) is converted to nitric oxide (NO) and l-citrulline (CIT) by endothelial nitric oxide synthase which is competitively inhibited by asymmetric…”
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Arctigenin Inhibits Adipogenesis by Inducing AMPK Activation and Reduces Weight Gain in High-Fat Diet-Induced Obese Mice by Han, Yo-Han, Kee, Ji-Ye, Park, Jinbong, Kim, Hye-Lin, Jeong, Mi-Young, Kim, Dae-Seung, Jeon, Yong-Deok, Jung, Yunu, Youn, Dong-Hyun, Kang, JongWook, So, Hong-Seob, Park, Raekil, Lee, Jong-Hyun, Shin, Soyoung, Kim, Su-Jin, Um, Jae-Young, Hong, Seung-Heon

“…ABSTRACT Although arctigenin (ARC) has been reported to have some pharmacological effects such as anti‐inflammation, anti‐cancer, and antioxidant, there have…”
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Physiologically Relevant In Vitro-In Vivo Correlation (IVIVC) Approach for Sildenafil with Site-Dependent Dissolution by Kim, Tae Hwan, Shin, Soyoung, Jeong, Seok Won, Lee, Jong Bong, Shin, Beom Soo

“…This study aimed to establish a physiologically relevant in vitro-in vivo correlation (IVIVC) model reflecting site-dependent dissolution kinetics for…”
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