Search Results - "SHIN, HWA KYOUNG"

Migraine Mutations Increase Stroke Vulnerability by Facilitating Ischemic Depolarizations by EIKERMANN-HAERTER, Katharina, JEONG HYUN LEE, FERRARI, Michel D, VAN DEN MAAGDENBERG, Arn M. J. M, MOSKOWITZ, Michael A, AYATA, Cenk, YUZAWA, Izumi, LIU, Christina H, ZHIPENG ZHOU, HWA KYOUNG SHIN, YI ZHENG, TAO QIN, KURTH, Tobias, WAEBER, Christian

“…Migraine is an independent risk factor for stroke. Mechanisms underlying this association are unclear. Familial hemiplegic migraine (FHM), a migraine subtype…”
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Probucol inhibits LPS-induced microglia activation and ameliorates brain ischemic injury in normal and hyperlipidemic mice by Jung, Yeon Suk, Park, Jung Hwa, Kim, Hyunha, Kim, So Young, Hwang, Ji Young, Hong, Ki Whan, Bae, Sun Sik, Choi, Byung Tae, Lee, Sae-Won, Shin, Hwa Kyoung

“…Aim： Increasing evidence suggests that probucol, a lipid-lowering agent with anti-oxidant activities, may be useful for the treatment of ischemic stroke with…”
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Mild Induced Hypertension Improves Blood Flow and Oxygen Metabolism in Transient Focal Cerebral Ischemia by KYOUNG SHIN, Hwa, NISHIMURA, Masaki, JONES, Phillip B, AY, Hakan, BOAS, David A, MOSKOWITZ, Michael A, AYATA, Cenk

“…In focal ischemic cortex, cerebral blood flow autoregulation is impaired, and perfusion passively follows blood pressure variations. Although it is generally…”
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Comparison of single nucleotide polymorphisms and short tandem repeats as markers for differentiating between donors and recipients in solid organ transplantation by Lee, Hyun-Ji, Shin, Kyoung-Hwa, Jeong, Su Jeong, Kim, In Suk

“…Background : To analyze transplant rejection and to distinguish between donor and recipient, it is necessary to select a marker from single nucleotide…”
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The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo by Atochin, Dmitriy N, Wang, Annie, Liu, Victor W T, Critchlow, Jeffrey D, Dantas, Ana Paula V, Looft-Wilson, Robin, Murata, Takahisa, Salomone, Salvatore, Shin, Hwa Kyoung, Ayata, Cenk, Moskowitz, Michael A, Michel, Thomas, Sessa, William C, Huang, Paul L

“…NO plays critical roles in vascular function. We show that modulation of the eNOS serine 1179 (S1179) phosphorylation site affects vascular reactivity and…”
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Linking Notch Signaling to Ischemic Stroke by Arboleda-Velasquez, Joseph F., Zhou, Zhipeng, Shin, Hwa Kyoung, Louvi, Angeliki, Kim, Hyung-Hwan, Savitz, Sean I., Liao, James K., Salomone, Salvatore, Ayata, Cenk, Moskowitz, Michael A., Artavanis-Tsakonas, Spyros

“…Vascular smooth muscle cells (SMCs) have been implicated in the pathophysiology of stroke, the third most common cause of death and the leading cause of…”
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AIM2 inflammasome contributes to brain injury and chronic post-stroke cognitive impairment in mice by Kim, Hyunha, Seo, Ji Seon, Lee, Seo-Yeon, Ha, Ki-Tae, Choi, Byung Tae, Shin, Yong-Il, Ju Yun, Young, Shin, Hwa Kyoung

“…•Ischemic brain injury impaired cognitive function at 28 days post-stroke in mice.•Ischemic brain injury triggered AIM2 inflammasome-mediated inflammation…”
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3D Bioprinted Vascularized Tumour for Drug Testing by Han, Seokgyu, Kim, Sein, Chen, Zhenzhong, Shin, Hwa Kyoung, Lee, Seo-Yeon, Moon, Hyo Eun, Paek, Sun Ha, Park, Sungsu

“…An in vitro screening system for anti-cancer drugs cannot exactly reflect the efficacy of drugs in vivo, without mimicking the tumour microenvironment (TME),…”
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Combination therapy with cilostazol, aripiprazole, and donepezil protects neuronal cells from β-amyloid neurotoxicity through synergistically enhanced SIRT1 expression by Heo, Hye Jin, Park, So Youn, Lee, Yi Sle, Shin, Hwa Kyoung, Hong, Ki Whan, Kim, Chi Dae

“…Alzheimer's disease (AD) is a multi-faceted neurodegenerative disease. Thus, current therapeutic strategies require multitarget-drug combinations to treat or…”
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Concurrent Treatment with Taxifolin and Cilostazol on the Lowering of β-Amyloid Accumulation and Neurotoxicity via the Suppression of P-JAK2/P-STAT3/NF-κB/BACE1 Signaling Pathways by Park, So Youn, Kim, Hae Young, Park, Hee Jeong, Shin, Hwa Kyoung, Hong, Ki Whan, Kim, Chi Dae

“…Taxifolin is a potent flavonoid that exerts anti-oxidative effect, and cilostazol increases intracellular cAMP levels by inhibiting phosphodiesterase 3 that…”
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Fingolimod provides long-term protection in rodent models of cerebral ischemia by Wei, Ying, Yemisci, Muge, Kim, Hyung-Hwan, Yung, Lai Ming, Shin, Hwa Kyoung, Hwang, Seo-Kyoung, Guo, Shuzhen, Qin, Tao, Alsharif, Nafiseh, Brinkmann, Volker, Liao, James K, Lo, Eng H, Waeber, Christian

“…Objective: The sphingosine‐1‐phosphate (S1P) receptor agonist fingolimod (FTY720), that has shown efficacy in advanced multiple sclerosis clinical trials,…”
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Electroacupuncture promotes post-stroke functional recovery via enhancing endogenous neurogenesis in mouse focal cerebral ischemia by Kim, Yu Ri, Kim, Ha Neui, Ahn, Sung Min, Choi, Yung Hyun, Shin, Hwa Kyoung, Choi, Byung Tae

“…To investigate the question of whether electroacupuncture (EA) promotes functional recovery via enhancement of proliferation and differentiation of neuronal…”
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Cilostazol Modulates Autophagic Degradation of β-Amyloid Peptide via SIRT1-Coupled LKB1/AMPKα Signaling in Neuronal Cells by Park, So Youn, Lee, Hye Rin, Lee, Won Suk, Shin, Hwa Kyoung, Kim, Hye Young, Hong, Ki Whan, Kim, Chi Dae

“…A neuroprotective role of autophagy mediates the degradation of β-amyloid peptide (Aβ) in Alzheimer's disease (AD). The previous study showed cilostazol…”
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Potential benefits of mesenchymal stem cells and electroacupuncture on the trophic factors associated with neurogenesis in mice with ischemic stroke by Kim, Yu Ri, Ahn, Sung Min, Pak, Malk Eun, Lee, Hong Ju, Jung, Da Hee, Shin, Yong-Il, Shin, Hwa Kyoung, Choi, Byung Tae

“…The beneficial effects of mesenchymal stem cells (MSCs) and electroacupuncture (EA) on neurogenesis and related trophic factors remain unclear. Bone marrow…”
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The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke by Kim, Sinai, Lee, Wonhyo, Jo, Huiju, Sonn, Seong-Keun, Jeong, Se-Jin, Seo, Seungwoon, Suh, Joowon, Jin, Jing, Kweon, Hyae Yon, Kim, Tae Kyeong, Moon, Shin Hye, Jeon, Sejin, Kim, Jong Woo, Kim, Yu Ri, Lee, Eun-Woo, Shin, Hwa Kyoung, Park, Sung Ho, Oh, Goo Taeg

“…Ischemic stroke is the leading cause of immortal disability and death worldwide. For treatment in the acute phase, it is necessary to control excessive…”
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Electroacupuncture acutely improves cerebral blood flow and attenuates moderate ischemic injury via an endothelial mechanism in mice by Kim, Ji Hyun, Choi, Kyung Ha, Jang, Young Jung, Bae, Sun Sik, Shin, Byung-Cheul, Choi, Byung Tae, Shin, Hwa Kyoung

“…Electroacupuncture (EA) is a novel therapy based on traditional acupuncture combined with modern eletrotherapy that is currently being investigated as a…”
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Sex-specific responses to juvenile stress on the dopaminergic system in an animal model of attention-deficit hyperactivity disorder by Jung, Da Hee, Lee, Hong Ju, Choi, Young Whan, Shin, Hwa Kyoung, Choi, Byung Tae

“…The etiology of attention-deficit hyperactivity disorder (ADHD) strongly suggests a genetic component as the main cause; however, environmental factors such as…”
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Weisheng-tang protects against ischemic brain injury by modulating microglia activation through the P2Y12 receptor by Kim, Min Jae, Lee, Dohee, Ryu, Ji Hye, Lee, Seo-Yeon, Choi, Byung Tae, Yun, Young Ju, Shin, Hwa Kyoung

“…Stroke, a leading cause of death and disability, lacks effective treatments. Post-stroke secondary damage worsens the brain microenvironment, further…”
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Electroacupuncture ameliorates memory impairments by enhancing oligodendrocyte regeneration in a mouse model of prolonged cerebral hypoperfusion by Ahn, Sung Min, Kim, Yu Ri, Kim, Ha Neui, Shin, Yong-Il, Shin, Hwa Kyoung, Choi, Byung Tae

“…We modeled prolonged cerebral hypoperfusion in mice using bilateral common carotid artery stenosis (BCAS) and electroacupuncture (EA) stimulation was applied…”
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Effect of Combination Electroacupuncture and Tenuigenin on the Migration and Differentiation of Mesenchymal Stem Cells following Ischemic Stroke by Lee, Jae Ho, Choi, Byung Tae, Shin, Hwa Kyoung

“…Since stroke is a serious health issue, novel therapeutic strategies are required. In a mouse model of ischemic stroke, this study analyzed the potential of…”
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