Search Results - "SHIMA, KAZUHIRO"

Formation of massive, dense cores by cloud–cloud collisions by Takahira, Ken, Shima, Kazuhiro, Habe, Asao, Tasker, Elizabeth J

“…Abstract We performed sub-parsec (∼ 0.014 pc) scale simulations of cloud–cloud collisions of two idealized turbulent molecular clouds (MCs) with different…”
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Identification of a vesicular ATP release inhibitor for the treatment of neuropathic and inflammatory pain by Kato, Yuri, Hiasa, Miki, Ichikawa, Reiko, Hasuzawa, Nao, Kadowaki, Atsushi, Iwatsuki, Ken, Shima, Kazuhiro, Endo, Yasuo, Kitahara, Yoshiro, Inoue, Tsuyoshi, Nomura, Masatoshi, Omote, Hiroshi, Moriyama, Yoshinori, Miyaji, Takaaki

“…Despite the high incidence of neuropathic and inflammatory pain worldwide, effective drugs with few side effects are currently unavailable for the treatment of…”
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The effect of photoionizing feedback on star formation in isolated and colliding clouds by Shima, Kazuhiro, Tasker, Elizabeth J, Federrath, Christoph, Habe, Asao

“…Abstract We investigate star formation occurring in idealized giant molecular clouds, comparing structures that evolve in isolation versus those undergoing a…”
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The Bisphosphonates Clodronate and Etidronate Exert Analgesic Effects by Acting on Glutamate- and/or ATP-Related Pain Transmission Pathways by Shima, Kazuhiro, Nemoto, Wataru, Tsuchiya, Masahiro, Tan-No, Koichi, Takano-Yamamoto, Teruko, Sugawara, Shunji, Endo, Yasuo

“…Bisphosphonates (BPs) are typical anti-bone-resorptive drugs, with nitrogen-containing BPs (N-BPs) being stronger than non-nitrogen-containing BPs (non-N-BPs)…”
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The Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 Inhibits Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption via Inhibition of TNF-α Expression in Macrophages by Kitaura, Hideki, Qi, Jiawei, Shima, Kazuhiro, Kishikawa, Akiko, Sugisawa, Haruki, Ishida, Masahiko, Kimura, Keisuke, Shen, Wei-Ren, Ogawa, Saika

“…Glucagon-like peptide-1 (GLP-1) receptor agonists are an effective treatment approach for type 2 diabetes. Recently, anti-inflammatory effects of GLP-1…”
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Inflammatory Effects of Nitrogen-Containing Bisphosphonates (N-BPs): Modulation by Non-N-BPs by Shima, Kazuhiro, Tsuchiya, Masahiro, Oizumi, Takefumi, Takano-Yamamoto, Teruko, Sugawara, Shunji, Endo, Yasuo

“…Bisphosphonates (BPs) are used against diseases with enhanced bone resorption. Those classed as nitrogen-containing BPs (N-BPs) exhibit much stronger…”
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CO observations of the molecular gas in the Galactic H ii region Sh2-48: Evidence for cloud–cloud collision as a trigger of high-mass star formation by Torii, Kazufumi, Hattori, Yusuke, Matsuo, Mitsuhiro, Fujita, Shinji, Nishimura, Atsushi, Kohno, Mikito, Kuriki, Mika, Tsuda, Yuya, Minamidani, Tetsuhiro, Umemoto, Tomofumi, Kuno, Nario, Yoshiike, Satoshi, Ohama, Akio, Tachihara, Kengo, Fukui, Yasuo, Shima, Kazuhiro, Habe, Asao, Haworth, Thomas J

“…Abstract Sh2-48 is a Galactic H ii region, 3.8 kpc distant, with an O9.5-type star identified at its center. As a part of the FOREST Unbiased Galactic plane…”
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DPP-4 inhibitor impedes lipopolysaccharide-induced osteoclast formation and bone resorption in vivo by Ishida, Masahiko, Shen, Wei-Ren, Kimura, Keisuke, Kishikawa, Akiko, Shima, Kazuhiro, Ogawa, Saika, Qi, Jiawei, Ohori, Fumitoshi, Noguchi, Takahiro, Marahleh, Aseel, Kitaura, Hideki

“…•DPP-4 inhibitor inhibited LPS-induced osteoclast formation and bone resorption.•DPP-4 inhibitor inhibited LPS-induced osteoclast-related cytokines in…”
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C-X-C Motif Chemokine 12 Enhances Lipopolysaccharide-Induced Osteoclastogenesis and Bone Resorption In Vivo by Shima, Kazuhiro, Kimura, Keisuke, Ishida, Masahiko, Kishikawa, Akiko, Ogawa, Saika, Qi, Jiawei, Shen, Wei-Ren, Ohori, Fumitoshi, Noguchi, Takahiro, Marahleh, Aseel, Kitaura, Hideki

“…C-X-C motif chemokine 12 (CXCL12) belongs to the family of CXC chemokines. Lipopolysaccharide (LPS) induces inflammation-induced osteoclastogenesis and bone…”
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Analgesic Effects of 1st Generation Anti-histamines in Mice by Takahashi, Mebae, Shima, Kazuhiro, Tsuchiya, Masahiro, Hagiwara, Yoshihiro, Mizoguchi, Hirokazu, Sakurada, Shinobu, Sugawara, Shunji, Fujita, Takuo, Tadano, Takeshi, Watanabe, Makoto, Fukumoto, Satoshi, Endo, Yasuo

“…Pain is sensed, transmitted, and modified by a variety of mediators and receptors. Histamine is a well-known mediator of pain. In addition to their…”
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Effect of Anti-c-fms Antibody on Osteoclast Formation and Proliferation of Osteoclast Precursor In Vitro by Marahleh, Aseel, Kitaura, Hideki, Ishida, Masahiko, Shima, Kazuhiro, Kishikawa, Akiko, Ogawa, Saika, Shen, Wei-Ren, Qi, Jiawei, Ohori, Fumitoshi, Noguchi, Takahiro, Nara, Yasuhiko, Mizoguchi, Itaru

“…Bone remodeling is a complex process and it involves periods of deposition and resorption. Bone resorption is a process by which bone is broken down by…”
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Role of Muramyl Dipeptide in Lipopolysaccharide-Mediated Biological Activity and Osteoclast Activity by Shen, Wei-Ren, Qi, Jiawei, Shima, Kazuhiro, Kishikawa, Akiko, Sugisawa, Haruki, Kimura, Keisuke, Ishida, Masahiko, Kitaura, Hideki, Ogawa, Saika

“…Lipopolysaccharide (LPS) is an endotoxin and bacterial cell wall component that is capable of inducing inflammation and immunological activity. Muramyl…”
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Does feedback help or hinder star formation? The effect of photoionisation on star formation in Giant Molecular Clouds by Shima, Kazuhiro, Tasker, Elizabeth J., Habe, Asao

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Gravitational fragmentation of extremely metal-poor circumstellar discs by Shima, Kazuhiro, Hosokawa, Takashi

“…ABSTRACT We study the gravitational fragmentation of circumstellar discs accreting extremely metal-poor ($Z \le 10^{-3}\, \mathrm{Z}_{\odot }$) gas, performing…”
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骨吸収抑制薬bisphosphonatesによる顎骨壊死の機序・予防・治療に関する基礎研究 by 遠藤, 康男, 船山, ひろみ, 山口, 晃史, 門馬, 祐子, 兪, 志前, 鄧, 雪, 大泉, 丈史, 四釜, 洋介, 田中, 志典, 岡田, 諭, 金, 始瑛, 木山, 朋美, 坂東, 加南, 島, 和弘, 鈴木, 飛佳理, 高橋, 哲

“…「1. はじめに」ピロリン酸の研究から始まったbisphosphonates(BPs)(以前はdiphosphonatesと呼称)の研究は, 現在, 骨転移性がん(乳がん, 前立腺がん, 肺がんなど)・多発性骨髄腫・骨粗鬆症・骨形成不全など, 骨吸収亢進を伴う広い疾患へのBPsの応用に至っている…”
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Analgesic Effects of 1st Generation Anti-histamines in Mice by Mebae Takahashia, b, Kazuhiro Shimaa, Masahiro Tsuchiyac, Yoshihiro Hagiwarad, Hirokazu Mizoguchie, Shinobu Sakuradae, Shunji Sugawaraa, Takuo Fujitaf, Takeshi Tadanog, Makoto Watanabec, Satoshi Fukumotob, Yasuo Endoa

“…Pain is sensed, transmitted, and modified by a variety of mediators and receptors. Histamine is a well-known mediator of pain. In addition to their…”
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A New Look at the Molecular Gas in M42 and M43: Possible Evidence for Cloud-Cloud Collision that Triggered Formation of the OB Stars in the Orion Nebula Cluster by Fukui, Yasuo, Torii, Kazufumi, Hattori, Yusuke, Nishimura, Atsushi, Ohama, Akio, Shimajiri, Yoshito, Shima, Kazuhiro, Habe, Asao, Sano, Hidetoshi, Kohno, Mikito, Yamamoto, Hiroaki, Tachihara, Kengo, Onishi, Toshikazu

“…The Orion Nebula Cluster toward the H ii region M42 is the most outstanding young cluster at the smallest distance (410 pc) among the rich high-mass stellar…”
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Large-scale CO J = 1–0 observations of the giant molecular cloud associated with the infrared ring N35 with the Nobeyama 45 m telescope by Torii, Kazufumi, Fujita, Shinji, Matsuo, Mitsuhiro, Nishimura, Atsushi, Kohno, Mikito, Kuriki, Mika, Tsuda, Yuya, Minamidani, Tetsuhiro, Umemoto, Tomofumi, Kuno, Nario, Hattori, Yusuke, Yoshiike, Satoshi, Ohama, Akio, Tachihara, Kengo, Shima, Kazuhiro, Habe, Asao, Fukui, Yasuo

“…Abstract We report an observational study of the giant molecular cloud (GMC) associated with the Galactic infrared ring-like structure N35 and two nearby H ii…”
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Outer rotation curve of the Galaxy with VERA. IV. Astrometry of IRAS 01123+6430 and the possibility of cloud–cloud collision by Koide, Nagito, Nakanishi, Hiroyuki, Sakai, Nobuyuki, Habe, Asao, Shima, Kazuhiro, Kurayama, Tomoharu, Matsuo, Mitsuhiro, Tezuka, Daisuke, Kurahara, Kohei, Ueno, Saeko, Burns, Ross A, Nakagawa, Akiharu, Honma, Mareki, Shibata, Katsunori M, Nagayama, Takumi, Kawaguchi, Noriyuki

“…As part our investigation into the Galactic rotation curve, we carried out Very Long Baseline Interferometry (VLBI) observations towards the star-forming…”
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Basic Studies on the Mechanism, Prevention, and Treatment of Osteonecrosis of the Jaw Induced by Bisphosphonates by Endo, Yasuo, Funayama, Hiromi, Yamaguchi, Kouji, Monma, Yuko, Yu, Zhiqian, Deng, Xue, Oizumi, Takefumi, Shikama, Yosuke, Tanaka, Yukinori, Okada, Satoshi, Kim, Siyoung, Kiyama, Tomomi, Bando, Kanan, Shima, Kazuhiro, Suzuki, Hikari, Takahashi, Tetsu

“…Since the first report in 2003, bisphosphonate-related osteonecrosis of the jaw (BRONJ) has been increasing, without effective clinical strategies…”
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