Search Results - "SHIKANO, T"

Successful laparoscopic deroofing for liver cysts: Our technique and outcome by Shikano, T

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A high incidence of selection on physiologically important genes in the three-spined stickleback, Gasterosteus aculeatus by Shimada, Yukinori, Shikano, Takahito, Merilä, Juha

“…Genome scan approaches to detect footprints of directional selection in the genomes of wild animal and plant populations have become popular tools to study…”
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A phase I dose-escalation clinical trial of intraoperative direct intratumoral injection of HF10 oncolytic virus in non-resectable patients with advanced pancreatic cancer by Nakao, A, Kasuya, H, Sahin, T T, Nomura, N, Kanzaki, A, Misawa, M, Shirota, T, Yamada, S, Fujii, T, Sugimoto, H, Shikano, T, Nomoto, S, Takeda, S, Kodera, Y, Nishiyama, Y

“…In 2005, we initiated a clinical trial that examined the efficacy of the oncolytic virus HF10 to treat pancreatic cancer. Pancreatic cancer continues to have a…”
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Identification of local- and habitat-dependent selection: scanning functionally important genes in nine-spined sticklebacks (Pungitius pungitius) by Shikano, Takahito, Ramadevi, Jetty, Merilä, Juha

“…Understanding the selective forces promoting adaptive population divergence is a central issue in evolutionary biology. The role of environmental salinity in…”
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A universal and reliable assay for molecular sex identification of three-spined sticklebacks (Gasterosteus aculeatus) by Toli, E.-A., Calboli, F.C.F., Shikano, T., Merilä, J.

“…In heterogametic species, biological differences between the two sexes are ubiquitous, and hence, errors in sex identification can be a significant source of…”
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Impact of novel oncolytic virus HF10 on cellular components of the tumor microenviroment in patients with recurrent breast cancer by Sahin, T T, Kasuya, H, Nomura, N, Shikano, T, Yamamura, K, Gewen, T, Kanzaki, A, Fujii, T, Sugae, T, Imai, T, Nomoto, S, Takeda, S, Sugimoto, H, Kikumori, T, Kodera, Y, Nishiyama, Y, Nakao, A

“…Oncolytic viruses are a promising method of cancer therapy, even for advanced malignancies. HF10, a spontaneously mutated herpes simplex type 1, is a potent…”
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Antitumor efficacy of oncolytic herpes simplex virus adsorbed onto antigen-specific lymphocytes by Kanzaki, A, Kasuya, H, Yamamura, K, Sahin, T T, Nomura, N, Shikano, T, Shirota, T, Tan, G, Fukuda, S, Misawa, M, Nishikawa, Y, Yamada, S, Fujii, T, Sugimoto, H, Nomoto, S, Takeda, S, Kodera, Y, Nakao, A

“…Although several studies have reported that locally administering oncolytic viruses effectively targets malignancies, the efficacy of systemically administered…”
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Relationships between genetic variation measured by microsatellite DNA markers and a fitness-related trait in the guppy ( Poecilia reticulata) by Shikano, Takahito, Taniguchi, Nobuhiko

“…We explored two microsatellite-based variables, heterozygosity and a measure of genomic diversity based on the mean squared distance between microsatellite…”
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Pure laparoscopic right and left hepatectomy with umbilical zigzag skin incision by Shikano, T.

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Oncolytic virus therapy--foreword by Kasuya, H, Takeda, S, Shimoyama, S, Shikano, T, Nomura, N, Kanazumi, N, Nomoto, S, Sugimoto, H, Nakao, A

“…We are very pleased and proud to be able to publish this special issue of Current Cancer Drug Targets devoted to oncolytic virus therapy covering basic and…”
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Suitability of a US3-inactivated HSV mutant (L1BR1) as an oncolytic virus for pancreatic cancer therapy by Kasuya, H, Nishiyama, Y, Nomoto, S, Goshima, F, Takeda, S, Watanabe, I, Nomura, N, Shikano, T, Fujii, T, Kanazumi, N, Nakao, A

“…Recently, the use of oncolytic viruses against cancer has attracted considerable attention. We studied the potential of the US3 locus-deficient herpes simplex…”
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Transumbilical laparoscopic surgery using GelPort through an umbilical zigzag skin incision by Hachisuka, T, Kinoshita, T, Yamakawa, T, Kurata, N, Tsutsuyama, M, Umeda, S, Tokunaga, S, Yarita, A, Shibata, M, Shimizu, D, Shikano, T, Hattori, K, Mori, T, Shinohara, M, Miyauchi, M

“…Introduction We report herein a new method of transumbilical laparoscopic surgery using a GelPort through an umbilical zigzag skin incision. The method…”
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High Susceptibility to Severe Infectious Complications at Reinduction Chemotherapy in Patients Who Relapse After Stem Cell Transplantation by Iguchi, A, Kobayashi, R, Sato, T.Z, Naito, H, Shikano, T, Ishikawa, Y, Kobayashi, K

“…Abstract Patients who relapse after stem cell transplantation (SCT) usually appear to be liable to severe infectious complications at reinduction chemotherapy…”
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Heterosis for neonatal survival in the guppy by Shikano, T, Taniguchi, N

“…Neonatal survival rate ranged from 91.8 to 100.0% in 12 populations of the guppy Poecilia reticulata, and was higher in naturalized Japanese stream populations…”
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Activity of a Sperm-Borne Oocyte-Activating Factor in Spermatozoa and Spermatogenic Cells from Cynomolgus Monkeys and Its Localization after Oocyte Activation by OGONUKI, Narumi, SANKAI, Tadashi, YAGAMI, Kenichi, SHIKANO, Tomohide, ODA, Shoji, MIYAZAKI, Shunichi, OGURA, Atsuo

“…It is widely accepted that mature mammalian oocytes are induced to resume meiosis by a sperm-borne oocyte-activating factor(s) (sperm factor, SF) immediately…”
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Perceptual processing and search efficiency of young and older adults in a simple-feature search task: A staircase approach by DAVIS, Elizabeth Thorpe, FUJAWA, Greg, SHIKANO, Terry

“…The reasons that visual search may sometimes be difficult, especially for older adults, remain important research issues. This study investigated (a) whether…”
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Heterosis for neonatal survival in the guppy by Shikano, T., Taniguchi, N.

“…Neonatal survival rate ranged from 91.8 to 100.0% in 12 populations of the guppy Poecilia reticulata, and was higher in naturalized Japanese stream populations…”
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Neurological complications after stem cell transplantation in childhood by IGUCHI, A, KOBAYASHI, R, YOSHIDA, M, KANEDA, M, WATANABE, N, CHO, Y, ARIOKA, H, NAITO, H, SHIKANO, T, ISHIKAWA, Y

“…We analyzed the incidence of neurological complications in 77 patients receiving stem cell transplantation (SCT), and 12 patients (15.8%) had the following…”
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Temporal changes in allele frequency, genetic variation and inbreeding depression in small populations of the guppy, Poecilia reticulata by Shikano, Takahito, Chiyokubo, Takashi, Taniguchi, Nobuhiko

“…We established three closed lines of N=10 for the guppy Poecilia reticulata, to evaluate the relationships among temporal changes in allele frequency, genetic…”
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Adenophostin, a potent agonist of the inositol 1,4,5-trisphosphate receptor, is useful for fertilization of mouse oocytes injected with round spermatids leading to normal offspring by SATO, Y, MIYAZAKI, S, SHIKANO, T, MITSUHASHI, N, TAKEUCHI, H, MIKOSHIBA, K, KUWABARA, Y

“…Precursor male gametes such as round spermatids and secondary spermatocytes are known to possess the potential to achieve fertilization and embryonic…”
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