Search Results - "SHIELD, J. P. H"

A longitudinal study investigating change in BMI z-score in primary school-aged children and the association of child BMI z-score with parent BMI by Mears, R, Salway, R, Sharp, D, Shield, J P H, Jago, R

“…This paper aims to explore change in BMI z-score through childhood and the association between parent BMI and child BMI z-score. This is important to…”
Get full text

Clinical presentation of 6q24 transient neonatal diabetes mellitus (6q24 TNDM) and genotype–phenotype correlation in an international cohort of patients by Docherty, L. E., Kabwama, S., Lehmann, A., Hawke, E., Harrison, L., Flanagan, S. E., Ellard, S., Hattersley, A. T., Shield, J. P. H., Ennis, S., Mackay, D. J. G., Temple, I. K.

“…Aims/hypothesis 6q24 transient neonatal diabetes mellitus (TNDM) is a rare form of diabetes presenting in the neonatal period that remits during infancy but,…”
Get full text

Normalizing Eating Behavior Reduces Body Weight and Improves Gastrointestinal Hormonal Secretion in Obese Adolescents by Galhardo, J, Hunt, L. P, Lightman, S. L, Sabin, M. A, Bergh, C, Sodersten, P, Shield, J. P. H

“…Hypothesis: Retraining obese adolescents to eat more slowly will lead to beneficial changes in circulating concentrations of gastrointestinal satiety hormones…”
Get full text

Diazoxide-responsive hyperinsulinemic hypoglycemia caused by HNF4A gene mutations by Flanagan, S E, Kapoor, R R, Mali, G, Cody, D, Murphy, N, Schwahn, B, Siahanidou, T, Banerjee, I, Akcay, T, Rubio-Cabezas, O, Shield, J P H, Hussain, K, Ellard, S

“…ObjectiveThe phenotype associated with heterozygous HNF4A gene mutations has recently been extended to include diazoxide responsive neonatal hypoglycemia in…”
Get full text

Continuing rise of Type 2 diabetes incidence in children and young people in the UK by Candler, T. P., Mahmoud, O., Lynn, R. M., Majbar, A. A., Barrett, T. G., Shield, J. P. H.

“…Aims To estimate the incidence of Type 2 diabetes in children aged <17 years, compare this with similar data 10 years ago, and characterize clinical features…”
Get full text

Can foster care ever be justified for weight management? by Williams, G M G, Bredow, Maria, Barton, John, Pryce, Rebekah, Shield, J P H

“…Article nine of the UN Convention of the Rights of the Child states that ‘Children must not be separated from their parents unless it is in the best interests…”
Get full text

Adolescents' views and experiences of treatments for Type 2 diabetes: a qualitative study by Turner, K. M., Percival, J., Dunger, D. B., Olbers, T., Barrett, T., Shield, J. P. H.

“…Aim To explore adolescents' views and experiences of different treatments for Type 2 diabetes, in order to improve treatment concordance and consider how the…”
Get full text

Management and 1 year outcome for UK children with type 2 diabetes by Shield, J P H, Lynn, R, Wan, K C, Haines, L, Barrett, T G

“…Objective:To report the 1-year outcome for children newly diagnosed as having type 2 diabetes in the UK.Design:Follow-up study of a UK national…”
Get full text

Is there a place for bariatric surgery in treating childhood obesity? by Shield, J P H, Crowne, E, Morgan, J

Get full text

Adolescent experiences of anti-obesity drugs by White, B., Jamieson, L., Clifford, S., Shield, J. P. H., Christie, D., Smith, F., Wong, I. C. K., Viner, R. M.

“…Summary Only two anti‐obesity drugs (AODs) are frequently prescribed in paediatric obesity, orlistat and metformin. Meta‐analyses show modest benefit in…”
Get full text

A maternal hypomethylation syndrome presenting as transient neonatal diabetes mellitus by MACKAY, D. J. G, BOONEN, S. E, SHIELD, J. P. H, WHITE, H. E, TEMPLE, I. K, CLAYTON-SMITH, J, GOODSHIP, J, HAHNEMANN, J. M. D, KANT, S. G, NJOLSTAD, P. R, ROBIN, N. H, ROBINSON, D. O, SIEBERT, R

Get full text

What reduction in BMI SDS is required in obese adolescents to improve body composition and cardiometabolic health? by Ford, Anna L, Hunt, Linda P, Cooper, Ashley, Shield, Julian P H

“…Objective To study the impact of body mass index (BMI) SD score (SDS) improvement through lifestyle modification on metabolic risk and body composition over 12…”
Get full text

Clinical, enzymatic and molecular characterization of nine new patients with malonyl‐coenzyme A decarboxylase deficiency by Salomons, G. S., Jakobs, C., Pope, L. Landegge, Errami, A., Potter, M., Nowaczyk, M., Olpin, S., Manning, N., Raiman, J. A. J., Slade, T., Champion, M. P., Peck, D., Gavrilov, D., Hillman, R., Hoganson, G. E., Donaldson, K., Shield, J. P. H., Ketteridge, D., Wasserstein, M., Gibson, K. M.

“…Summary We report nine new patients with malonic aciduria associated with enzyme‐confirmed malonyl‐CoA decarboxylase (MCD) deficiency in eight. Clinical…”
Get full text

Elevated glucose concentrations during an oral glucose tolerance test are associated with the presence of metabolic syndrome in childhood obesity by Sabin, M. A., Hunt, L. P., Ford, A. L., Werther, G. A., Crowne, E. C., Shield, J. P. H.

“…Aims  To investigate whether changes in glucose concentrations during an OGTT in obese children reflect the presence of peripheral insulin resistance and/or…”
Get full text

How does physical activity and fitness influence glycaemic control in young people with Type 1 diabetes? by Cuenca-García, M., Jago, R., Shield, J. P. H., Burren, C. P.

“…Diabet. Med. 29, e369–e376 (2012) Aims  To assess physical activity and fitness levels of young people with Type 1 diabetes compared with siblings without…”
Get full text

Aetiopathology and genetic basis of neonatal diabetes by Shield, J P H, Gardner, R J, Wadsworth, E J K, Whiteford, M L, James, R S, Robinson, D O, Baum, J D, Temple, I K

“…A British Paediatric Association Surveillance Unit* study of neonatal diabetes determined a national incidence of 1 in 400 000 live births. Additional cases of…”
Get full text

Physical activity patterns in nonobese and obese children assessed using minute-by-minute accelerometry by PAGE, A, COOPER, A. R, STAMATAKIS, E, FOSTER, L. J, CROWNE, E. C, SABIN, M, SHIELD, J. P. H

“…To determine the levels and patterns of physical activity in a sample of obese (> or =99th percentile body mass index (BMI)) and nonobese (<99th percentile…”
Get full text

Transient neonatal diabetes, a disorder of imprinting by Temple, I K, Shield, J P H

“…Transient neonatal diabetes (TND) is a rare but distinct type of diabetes. Classically, neonates present with growth retardation and diabetes in the first week…”
Get full text

A maternal hypomethylation syndrome presenting as transient neonatal diabetes mellitus by Mackay, D J G, Boonen, S E, Clayton-Smith, J, Goodship, J, Hahnemann, J M D, Kant, S G, Njølstad, P R, Robin, N H, Robinson, D O, Siebert, R, Shield, J P H, White, H E, Temple, I K

“…The expression of imprinted genes is mediated by allele-specific epigenetic modification of genomic DNA and chromatin, including parent of origin-specific DNA…”
Get full text

Obesity and disability - a short review by Ells, L. J., Lang, R., Shield, J. P. H., Wilkinson, J. R., Lidstone, J. S. M., Coulton, S., Summerbell, C. D.

“…Summary The prevalence of both obesity and disability is increasing globally and there is now growing evidence to suggest that these two health priorities may…”
Get full text