Search Results - "SHIBAZAKI, MASAHIKO"

DUSP4 Inactivation Leads to Reduced Extracellular Signal‒Regulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells by Kamada, Hirofumi, Yasuhira, Shinji, Shibazaki, Masahiko, Amano, Hiroo, Maesawa, Chihaya

“…A subset of dual-specificity phosphatases is a major negative regulator of MAPKs, and their involvement in tumorigenesis remains controversial. Among them,…”
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Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53 by Yasuhira, Shinji, Shibazaki, Masahiko, Nishiya, Masao, Maesawa, Chihaya

“…Spindle poisons elicit various cellular responses following metaphase arrest, but how they relate to long-term clonogenicity has remained unclear. We prepared…”
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Loss of HOXD10 expression induced by upregulation of miR-10b accelerates the migration and invasion activities of ovarian cancer cells by NAKAYAMA, IKUE, SHIBAZAKI, MASAHIKO, YASHIMA-ABO, AKIKO, MIURA, FUMIHARU, SUGIYAMA, TORU, MASUDA, TOMOYUKI, MAESAWA, CHIHAYA

“…Small and large non-coding RNAs (ncRNAs) contribute to the acquisition of aggressive tumor behavior in diverse human malignancies. Two types of ncRNAs,…”
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Downregulation of miR‐138 is associated with overexpression of human telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell lines by Mitomo, Shingo, Maesawa, Chihaya, Ogasawara, Satoshi, Iwaya, Takeshi, Shibazaki, Masahiko, Yashima‐Abo, Akiko, Kotani, Koji, Oikawa, Hiroki, Sakurai, Eiich, Izutsu, Naoko, Kato, Kuniyuki, Komatsu, Hideaki, Ikeda, Kenichro, Wakabayashi, Go, Masuda, Tomoyuki

“…Alterations of several microRNA (miRNA) have been linked to cancer development and its biology. To search for unique miRNA that might play a role in the…”
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Involvement of C-terminal truncation mutation of kinesin-5 in resistance to kinesin-5 inhibitor by Saeki, Eri, Yasuhira, Shinji, Shibazaki, Masahiko, Tada, Hiroshi, Doita, Minoru, Masuda, Tomoyuki, Maesawa, Chihaya

“…Cultured cells easily develop resistance to kinesin-5 inhibitors (K5Is) often by overexpressing a related motor protein, kinesin-12/KIF15, or by acquiring…”
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Correction: Involvement of C-terminal truncation mutation of kinesin-5 in resistance to kinesin-5 inhibitor by Saeki, Eri, Yasuhira, Shinji, Shibazaki, Masahiko, Tada, Hiroshi, Doita, Minoru, Masuda, Tomoyuki, Maesawa, Chihaya

“…[This corrects the article DOI: 10.1371/journal.pone.0209296.]…”
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Fluvastatin exerts an antitumor effect in vemurafenib-resistant melanoma cells by Nishiya, Masao, Yasuhira, Shinji, Shibazaki, Masahiko, Oikawa, Hiroki, Masuda, Tomoyuki, Maesawa, Chihaya

“…Although vemurafenib has been shown to improve the overall survival of patients with metastatic melanoma harboring the BRAF V600E mutation, its efficacy is…”
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Hyaluronic acid enhances cell migration and invasion via the YAP1/TAZ-RHAMM axis in malignant pleural mesothelioma by Shigeeda, Wataru, Shibazaki, Masahiko, Yasuhira, Shinji, Masuda, Tomoyuki, Tanita, Tatsuo, Kaneko, Yuka, Sato, Tatsuhiro, Sekido, Yoshitaka, Maesawa, Chihaya

“…Most malignant mesotheliomas (MPMs) frequently show activated forms of Yes-associated protein 1 (YAP1) and transcriptional co-activator with PDZ-binding motif…”
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NAD(P)H:Quinone Oxidoreductase-1 Expression Sensitizes Malignant Melanoma Cells to the HSP90 Inhibitor 17-AAG by Kasai, Shuya, Arakawa, Nobuyuki, Okubo, Ayaka, Shigeeda, Wataru, Yasuhira, Shinji, Masuda, Tomoyuki, Akasaka, Toshihide, Shibazaki, Masahiko, Maesawa, Chihaya

“…The KEAP1-NRF2 pathway regulates cellular redox homeostasis by transcriptional induction of genes associated with antioxidant synthesis and detoxification in…”
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NAD(P)H dehydrogenase, quinone 1 (NQO1), protects melanin-producing cells from cytotoxicity of rhododendrol by Okubo, Ayaka, Yasuhira, Shinji, Shibazaki, Masahiko, Takahashi, Kazuhiro, Akasaka, Toshihide, Masuda, Tomoyuki, Maesawa, Chihaya

“…Summary Rhododendrol (RD) is a potent tyrosinase inhibitor that is metabolized to RD‐quinone by tyrosinase, which may underlie the cytotoxicity of RD and…”
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Nucleus accumbens associated 1 is recruited within the promyelocytic leukemia nuclear body through SUMO modification by Tatemichi, Yoshinori, Shibazaki, Masahiko, Yasuhira, Shinji, Kasai, Shuya, Tada, Hiroshi, Oikawa, Hiroki, Suzuki, Yuji, Takikawa, Yasuhiro, Masuda, Tomoyuki, Maesawa, Chihaya

“…Nucleus accumbens associated 1 (NACC1) is a cancer‐associated BTB/POZ (pox virus and zinc finger/bric‐a‐brac tramtrack broad complex) gene, and is involved in…”
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A Somatic Mutation of the KEAP1 Gene in Malignant Melanoma Is Involved in Aberrant NRF2 Activation and an Increase in Intrinsic Drug Resistance by Miura, Shinpei, Shibazaki, Masahiko, Kasai, Shuya, Yasuhira, Shinji, Watanabe, Ayano, Inoue, Tsuyoshi, Kageshita, Yuich, Tsunoda, Kanako, Takahashi, Kazuhiro, Akasaka, Toshihide, Masuda, Tomoyuki, Maesawa, Chihaya

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BCL2 and BCLxL are key determinants of resistance to antitubulin chemotherapeutics in melanoma cells by Watanabe, Ayano, Yasuhira, Shinji, Inoue, Tsuyoshi, Kasai, Shuya, Shibazaki, Masahiko, Takahashi, Kazuhiro, Akasaka, Toshihide, Masuda, Tomoyuki, Maesawa, Chihaya

“…Malignant melanoma is refractory to various chemotherapeutics including antitubulin agents such as paclitaxel. Previous studies have suggested a link between…”
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Immunohistochemistry for histone h3 lysine 9 methyltransferase and demethylase proteins in human melanomas by Miura, Shinpei, Maesawa, Chihaya, Shibazaki, Masahiko, Yasuhira, Shinji, Kasai, Syuya, Tsunoda, Kanako, Maeda, Fumihiko, Takahashi, Kazuhiro, Akasaka, Toshihide, Masuda, Tomoyuki

“…Methylation and demethylation of histone H3 lysine 9 (H3K9) play a role in the transcriptional regulation of several cancer-related genes and are closely…”
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Nucleus Accumbens-Associated 1 Contributes to Cortactin Deacetylation and Augments the Migration of Melanoma Cells by Tsunoda, Kanako, Oikawa, Hiroki, Tada, Hiroshi, Tatemichi, Yoshinori, Muraoka, Sosuke, Miura, Shinpei, Shibazaki, Masahiko, Maeda, Fumihiko, Takahashi, Kazuhiro, Akasaka, Toshihide, Masuda, Tomoyuki, Maesawa, Chihaya

“…We investigated the prognostic significance and post-transcriptional acetylation-modification of cortactin (CTTN) via the nucleus accumbens-associated 1…”
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Suppression by p38 MAP Kinase Inhibitors (Pyridinyl Imidazole Compounds) of Ah Receptor Target Gene Activation by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and the Possible Mechanism by Shibazaki, Masahiko, Takeuchi, Takashi, Ahmed, Sohel, Kikuchi, Hideaki

“…Cytochrome P-450 1A1 (CYP1A1) is known to be induced by aromatic hydrocarbons, such as 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD), through activation of the…”
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Complement-Dependent Accumulation and Degradation of Platelets in the Lung and Liver Induced by Injection of Lipopolysaccharides by SHIBAZAKI, M, KAWABATA, Y, YOKOCHI, T, NISHIDA, A, TAKADA, H, ENDO, Y

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Inhibition of inflammatory actions of aminobisphosphonates by dichloromethylene bisphosphonate, a non‐aminobisphosphonate by Endo, Yasuo, Shibazaki, Masahiko, Yamaguchi, Kouji, Nakamura, Masanori, Kosugi, Hiroshi

“…When injected intraperitoneally into mice in doses larger than those used clinically, all the amino derivatives of bisphosphonates (aminoBPs) tested induce a…”
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Contrasting Effects of Lipopolysaccharides (Endotoxins) from Oral Black-Pigmented Bacteria and Enterobacteriaceae on Platelets, a Major Source of Serotonin, and on Histamine-Forming Enzyme in Mice by Endo, Yasuo, Shibazaki, Masahiko, Nakamura, Masanori, Takada, Haruhiko

“…By measurement of serotonin levels, the translocation of platelets to various tissues was examined following intravenous injection of a lipopolysaccharide…”
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Protein oxidation inhibits NO-mediated signaling pathway for synaptic plasticity by Kakizawa, Sho, Shibazaki, Masahiko, Mori, Nozomu

“…Abstract Oxidative stress is a primary factor inducing brain dysfunction in aged animals. However, how oxidation affects brain function is not fully…”
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