Search Results - "SHIBATA, Toshio"

Effects of Ca2+ ions on the horseshoe crab coagulation cascade triggered by lipopolysaccharide by Yamashita, Keisuke, Takahashi, Daisuke, Yamamoto, Yuki, Kiyomoto, Shingo, Shibata, Toshio, Kawabata, Shun-Ichiro

“…The lipopolysaccharide (LPS)-triggered horseshoe crab coagulation cascade is composed of three protease zymogens, prochelicerase C (proC), prochelicerase B…”
Get full text

Pluripotency and a secretion mechanism of Drosophila transglutaminase by Shibata, Toshio, Kawabata, Shun-Ichiro

“…Transglutaminase (TG) catalyses the formation of an isopeptide bond between glutamine and lysine residues and amine incorporation into specific glutamine…”
Get full text

Passivity breakdown and stress corrosion cracking of stainless steel by Shibata, Toshio

“…Passivity breakdown of stainless steel is an important initial process for starting stress corrosion cracking. It was found that small amount of impurities in…”
Get full text

Roles of the clip domains of two protease zymogens in the coagulation cascade in horseshoe crabs by Yamashita, Keisuke, Shibata, Toshio, Takahashi, Toshiaki, Kobayashi, Yuki, Kawabata, Shun-ichiro

“…The lipopolysaccharide (LPS)-triggered coagulation cascade in horseshoe crabs comprises three protease zymogens: prochelicerase C (proC), prochelicerase B…”
Get full text

Drosophila TG-A transglutaminase is secreted via an unconventional Golgi-independent mechanism involving exosomes and two types of fatty acylations by Shibata, Toshio, Hadano, Jinki, Kawasaki, Daichi, Dong, Xiaoqing, Kawabata, Shun-ichiro

“…Transglutaminases (TGs) play essential intracellular and extracellular roles by covalently cross-linking many proteins. Drosophila TG is encoded by one gene…”
Get full text

Transglutaminase-catalyzed incorporation of polyamines masks the DNA-binding region of the transcription factor Relish by Maki, Kouki, Shibata, Toshio, Kawabata, Shun-ichiro

“…In Drosophila, the final immune deficiency (IMD) pathway-dependent signal is transmitted through proteolytic conversion of the nuclear factor-κB (NF-κB)-like…”
Get full text

A mutant equipped with a regenerated disulphide for the missing His loop of a serine protease zymogen in the horseshoe crab coagulation cascade by Yamashita, Keisuke, Takeshita, Naoki, Arita, Aina, Shibata, Toshio, Kobayashi, Yuki, Kawabata, Shun-ichiro

“…Abstract The lipopolysaccharide (LPS)-triggered coagulation cascade in horseshoe crabs is composed of three zymogens belonging to the trypsinogen family:…”
Get full text

Crosslinking of a Peritrophic Matrix Protein Protects Gut Epithelia from Bacterial Exotoxins by Shibata, Toshio, Maki, Kouki, Hadano, Jinki, Fujikawa, Takumi, Kitazaki, Kazuki, Koshiba, Takumi, Kawabata, Shun-ichiro

“…Transglutaminase (TG) catalyzes protein-protein crosslinking, which has important and diverse roles in vertebrates and invertebrates. Here we demonstrate that…”
Get full text

RNA Interference Directed against the Transglutaminase Gene Triggers Dysbiosis of Gut Microbiota in Drosophila by Sekihara, Sanae, Shibata, Toshio, Hyakkendani, Mai, Kawabata, Shun-ichiro

“…We recently reported that transglutaminase (TG) suppresses immune deficiency pathway-controlled antimicrobial peptides (IMD-AMPs), thereby conferring immune…”
Get full text

ppGpp functions as an alarmone in metazoa by Ito, Doshun, Kawamura, Hinata, Oikawa, Akira, Ihara, Yuta, Shibata, Toshio, Nakamura, Nobuhiro, Asano, Tsunaki, Kawabata, Shun-Ichiro, Suzuki, Takashi, Masuda, Shinji

“…Guanosine 3′,5′-bis(pyrophosphate) (ppGpp) functions as a second messenger in bacteria to adjust their physiology in response to environmental changes. In…”
Get full text

Factor B Is the Second Lipopolysaccharide-binding Protease Zymogen in the Horseshoe Crab Coagulation Cascade by Kobayashi, Yuki, Takahashi, Toshiaki, Shibata, Toshio, Ikeda, Shunsuke, Koshiba, Takumi, Mizumura, Hikaru, Oda, Toshio, Kawabata, Shun-ichiro

“…Factor B is a serine-protease zymogen in the horseshoe crab coagulation cascade, and it is the primary substrate for activated factor C, the LPS-responsive…”
Get full text

Sustainability design of concrete structures by Sakai, Koji, Shibata, Toshio, Kasuga, Akio, Nakamura, Hikaru

“…Concrete became the most used material on Earth over 200 years following the invention of modern cement. The design concept has undergone a transition from the…”
Get full text

The N-terminal Arg Residue Is Essential for Autocatalytic Activation of a Lipopolysaccharide-responsive Protease Zymogen by Kobayashi, Yuki, Shiga, Takafumi, Shibata, Toshio, Sako, Miyuki, Maenaka, Katsumi, Koshiba, Takumi, Mizumura, Hikaru, Oda, Toshio, Kawabata, Shun-ichiro

“…Factor C, a serine protease zymogen involved in innate immune responses in horseshoe crabs, is known to be autocatalytically activated on the surface of…”
Get full text

Semiconductive behavior of passive films formed on pure Cr and Fe–Cr alloys in sulfuric acid solution by Tsuchiya, Hiroaki, Fujimoto, Shinji, Chihara, Osamu, Shibata, Toshio

“…Photoelectrochemical current response and capacitance were analyzed for passive films formed on pure Cr and Fe–Cr alloys in sulfuric acid solution. The…”
Get full text

Factor C Acts as a Lipopolysaccharide-Responsive C3 Convertase in Horseshoe Crab Complement Activation by Ariki, Shigeru, Takahara, Shusaku, Shibata, Toshio, Fukuoka, Takaaki, Ozaki, Aya, Endo, Yuichi, Fujita, Teizo, Koshiba, Takumi, Kawabata, Shun-ichiro

“…The complement system in vertebrates plays an important role in host defense against and clearance of invading microbes, in which complement component C3 plays…”
Get full text

Microbe-specific C3b deposition in the horseshoe crab complement system in a C2/factor B-dependent or -independent manner by Tagawa, Keisuke, Yoshihara, Toyoki, Shibata, Toshio, Kitazaki, Kazuki, Endo, Yuichi, Fujita, Teizo, Koshiba, Takumi, Kawabata, Shun-ichiro

“…Complement C3 plays an essential role in the opsonization of pathogens in the mammalian complement system, whereas the molecular mechanism underlying C3…”
Get full text

Correction: Crosslinking of a Peritrophic Matrix Protein Protects Gut Epithelia from Bacterial Exotoxins by Shibata, Toshio, Maki, Kouki, Hadano, Jinki, Fujikawa, Takumi, Kitazaki, Kazuki, Koshiba, Takumi, Kawabata, Shun-Ichiro

“…[This corrects the article DOI: 10.1371/journal.ppat.1005244.]…”
Get full text

Sustainability evaluation of butterfly web bridge by Shibata, Toshio, Kata, Kenichi, Kasuga, Akio, Sakai, Koji

“…The authors developed the butterfly web bridge structure, an “innovative” bridge technology, to tackle the issues on lifespan extension, durability…”
Get full text

Protein crosslinking by transglutaminase controls cuticle morphogenesis in Drosophila by Shibata, Toshio, Ariki, Shigeru, Shinzawa, Naoaki, Miyaji, Ryuta, Suyama, Haruka, Sako, Miyuki, Inomata, Nobuyuki, Koshiba, Takumi, Kanuka, Hirotaka, Kawabata, Shun-Ichiro

“…Transglutaminase (TG) plays important and diverse roles in mammals, such as blood coagulation and formation of the skin barrier, by catalyzing protein…”
Get full text

Application of sustainability design to an existing viaduct in a hilly area by Shibata, Toshio, Asai, Hirotaka, Fujioka, Taisuke, Kasuga, Akio, Sakai, Koji

“…The World Commission on Environment and Development of the United Nations defined “sustainable development” for the first time in 1987, indicating the…”
Get full text