Search Results - "SHERMAN, Nicholas E"

Towards an arthritis flare-responsive drug delivery system by Joshi, Nitin, Yan, Jing, Levy, Seth, Bhagchandani, Sachin, Slaughter, Kai V., Sherman, Nicholas E., Amirault, Julian, Wang, Yufeng, Riegel, Logan, He, Xueyin, Rui, Tan Shi, Valic, Michael, Vemula, Praveen K., Miranda, Oscar R., Levy, Oren, Gravallese, Ellen M., Aliprantis, Antonios O., Ermann, Joerg, Karp, Jeffrey M.

“…Local delivery of therapeutics for the treatment of inflammatory arthritis (IA) is limited by short intra-articular half-lives. Since IA severity often…”
Get full text

Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9 by Yang, Chun-Song, Jividen, Kasey, Spencer, Adam, Dworak, Natalia, Ni, Li, Oostdyk, Luke T., Chatterjee, Mandovi, Kuśmider, Beata, Reon, Brian, Parlak, Mahmut, Gorbunova, Vera, Abbas, Tarek, Jeffery, Erin, Sherman, Nicholas E., Paschal, Bryce M.

“…ADP-ribosylation of proteins is emerging as an important regulatory mechanism. Depending on the family member, ADP-ribosyltransferases either conjugate a…”
Get full text

Proteomic analysis of cattle tick Rhipicephalus (Boophilus) microplus saliva: a comparison between partially and fully engorged females by Tirloni, Lucas, Reck, José, Terra, Renata Maria Soares, Martins, João Ricardo, Mulenga, Albert, Sherman, Nicholas E, Fox, Jay W, Yates, 3rd, John R, Termignoni, Carlos, Pinto, Antônio F M, Vaz, Jr, Itabajara da Silva

“…The cattle tick Rhipicephalus (Boophilus) microplus is one of the most harmful parasites affecting bovines. Similarly to other hematophagous ectoparasites, R…”
Get full text

Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells by Tong, Zhixiang, Martyn, Keir, Yang, Andy, Yin, Xiaolei, Mead, Benjamin E., Joshi, Nitin, Sherman, Nicholas E., Langer, Robert S., Karp, Jeffrey M.

“…Current ISC culture systems face significant challenges such as animal-derived or undefined matrix compositions, batch-to-batch variability (e.g…”
Get full text

Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly by Yang, Chun-Song, Jividen, Kasey, Kamata, Teddy, Dworak, Natalia, Oostdyk, Luke, Remlein, Bartlomiej, Pourfarjam, Yasin, Kim, In-Kwon, Du, Kang-Ping, Abbas, Tarek, Sherman, Nicholas E., Wotton, David, Paschal, Bryce M.

“…Androgen signaling through the androgen receptor (AR) directs gene expression in both normal and prostate cancer cells. Androgen regulates multiple aspects of…”
Get full text

Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function by Tao, Jifang, Hu, Keping, Chang, Qiang, Wu, Hao, Sherman, Nicholas E, Martinowich, Keri, Klose, Robert J, Schanen, Carolyn, Jaenisch, Rudolf, Wang, Weidong, Sun, Yi Eve

“…Mutations of MECP2 (Methyl-CpG Binding Protein 2) cause Rett syndrome. As a chromatin-associated multifunctional protein, how MeCP2 integrates external signals…”
Get full text

LMO7 deficiency reveals the significance of the cuticular plate for hearing function by Du, Ting-Ting, Dewey, James B., Wagner, Elizabeth L., Cui, Runjia, Heo, Jinho, Park, Jeong-Jin, Francis, Shimon P., Perez-Reyes, Edward, Guillot, Stacey J., Sherman, Nicholas E., Xu, Wenhao, Oghalai, John S, Kachar, Bechara, Shin, Jung-Bum

“…Sensory hair cells, the mechanoreceptors of the auditory and vestibular systems, harbor two specialized elaborations of the apical surface, the hair bundle and…”
Get full text

Characterization of a novel AraC/XylS-regulated family of N-acyltransferases in pathogens of the order Enterobacterales by Belmont-Monroy, Laura, Saitz-Rojas, Waleska, Soria-Bustos, Jorge, Mickey, Abigail S, Sherman, Nicholas E, Orsburn, Benjamin C, Ruiz-Perez, Fernando, Santiago, Araceli E

“…Enteroaggregative Escherichia coli (EAEC) is a diarrheagenic pathotype associated with traveler's diarrhea, foodborne outbreaks and sporadic diarrhea in…”
Get full text

Characterization of the interactome profiling of Mycoplasma fermentans DnaK in cancer cells reveals interference with key cellular pathways by Curreli, Sabrina, Benedetti, Francesca, Yuan, Weirong, Munawwar, Arshi, Cocchi, Fiorenza, Gallo, Robert C., Sherman, Nicholas E., Zella, Davide

“…Chaperone proteins are redundant in nature and, to achieve their function, they bind a large repertoire of client proteins. DnaK is a bacterial chaperone…”
Get full text

Matrix rigidity regulates cancer cell growth by modulating cellular metabolism and protein synthesis by Tilghman, Robert W, Blais, Edik M, Cowan, Catharine R, Sherman, Nicholas E, Grigera, Pablo R, Jeffery, Erin D, Fox, Jay W, Blackman, Brett R, Tschumperlin, Daniel J, Papin, Jason A, Parsons, J Thomas

“…Tumor cells in vivo encounter diverse types of microenvironments both at the site of the primary tumor and at sites of distant metastases. Understanding how…”
Get full text

DBC1 Regulates p53 Stability via Inhibition of CBP-Dependent p53 Polyubiquitination by Akande, Oluwatoyin E., Damle, Priyadarshan K., Pop, Marius, Sherman, Nicholas E., Szomju, Barbara B., Litovchick, Larisa V., Grossman, Steven R.

“…The control of p53 protein stability is critical to its tumor suppressor functions. The CREB binding protein (CBP) transcriptional co-activator co-operates…”
Get full text

Observation of Bothrops atrox Snake Envenoming Blister Formation from Five Patients: Pathophysiological Insights by Gimenes, Sarah N C, Sachett, Jacqueline A G, Colombini, Mônica, Freitas-de-Sousa, Luciana A, Ibiapina, Hiochelson N S, Costa, Allyson G, Santana, Monique F, Park, Jeong-Jin, Sherman, Nicholas E, Ferreira, Luiz C L, Wen, Fan H, Monteiro, Wuelton M, Moura-da-Silva, Ana M, Fox, Jay W

“…In the Brazilian Amazon, snakebites are frequent, and patients develop tissue damage with blisters sometimes observed in the proximity of the wound. Antivenoms…”
Get full text

Proteomic analysis of the cyst stage of Entamoeba histolytica by Ali, Ibne Karim M, Haque, Rashidul, Siddique, Abdullah, Kabir, Mamun, Sherman, Nicholas E, Gray, Sean A, Cangelosi, Gerard A, Petri, Jr, William A

“…The category B agent of bioterrorism, Entamoeba histolytica has a two-stage life cycle: an infective cyst stage, and an invasive trophozoite stage. Due to our…”
Get full text

Author Correction: Towards an arthritis flare-responsive drug delivery system by Joshi, Nitin, Yan, Jing, Levy, Seth, Bhagchandani, Sachin, Slaughter, Kai V., Sherman, Nicholas E., Amirault, Julian, Wang, Yufeng, Riegel, Logan, He, Xueyin, Rui, Tan Shi, Valic, Michael, Vemula, Praveen K., Miranda, Oscar R., Levy, Oren, Gravallese, Ellen M., Aliprantis, Antonios O., Ermann, Joerg, Karp, Jeffrey M.

“…In the original version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now been corrected to…”
Get full text

Entamoeba histolytica phagocytosis of human erythrocytes involves PATMK, a member of the transmembrane kinase family by Boettner, Douglas R, Huston, Christopher D, Linford, Alicia S, Buss, Sarah N, Houpt, Eric, Sherman, Nicholas E, Petri, Jr, William A

“…Entamoeba histolytica is the cause of amebic colitis and liver abscess. This parasite induces apoptosis in host cells and utilizes exposed ligands such as…”
Get full text

Integrated proteomics identified up-regulated focal adhesion-mediated proteins in human squamous cell carcinoma in an orthotopic murine model by Granato, Daniela C, Zanetti, Mariana R, Kawahara, Rebeca, Yokoo, Sami, Domingues, Romênia R, Aragão, Annelize Z, Agostini, Michelle, Carazzolle, Marcelo F, Vidal, Ramon O, Flores, Isadora L, Korvala, Johanna, Cervigne, Nilva K, Silva, Alan R S, Coletta, Ricardo D, Graner, Edgard, Sherman, Nicholas E, Paes Leme, Adriana F

“…Understanding the molecular mechanisms of oral carcinogenesis will yield important advances in diagnostics, prognostics, effective treatment, and outcome of…”
Get full text

Spatiotemporal Crossover between Low- and High-Temperature Dynamical Regimes in the Quantum Heisenberg Magnet by Dupont, Maxime, Sherman, Nicholas E., Moore, Joel E.

“…The stranglehold of low temperatures on fascinating quantum phenomena in one-dimensional quantum magnets has been challenged recently by the discovery of…”
Get full text

Dynamic Changes in Equatorial Segment Protein 1 (SPESP1) Glycosylation During Mouse Spermiogenesis1 by Suryavathi, Viswanadhapalli, Panneerdoss, Subbarayalu, Wolkowicz, Michael J, Shetty, Jagathpala, Sherman, Nicholas E, Flickinger, Charles J, Herr, John C

“…ESP1/SPESP1 is a testis-specific, postmeiotic gene expressed in round spermatids that encodes equatorial segment protein 1, an intra-acrosomal protein found in…”
Get full text

Autocatalytic Phosphorylation of CDK2 at the Activating Thr160 by Abbas, Tarek, Jha, Sudhakar, Sherman, Nicholas E., Dutta, Anindya

“…Phosphorylation of a critical residue in the activation loop of many protein kinases is essential for enzymatic activity. The trimeric complex CDK7/cyclin…”
Get full text

S6K1- and βTRCP-Mediated Degradation of PDCD4 Promotes Protein Translation and Cell Growth by Dorrello, N. Valerio, Peschiaroli, Angelo, Guardavaccaro, Daniele, Colburn, Nancy H, Sherman, Nicholas E, Pagano, Michele

“…The tumor suppressor programmed cell death protein 4 (PDCD4) inhibits the translation initiation factor eIF4A, an RNA helicase that catalyzes the unwinding of…”
Get full text