Search Results - "SHENG HE HUANG"

A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function by Gao, Jie, Li, Yubin, Wan, Yu, Hu, Tongtong, Liu, Liting, Yang, Shaojie, Gong, Zelong, Zeng, Qing, Wei, Yi, Yang, Weijun, Zeng, Zhijie, He, Xiaolong, Huang, Sheng-He, Cao, Hong

“…It has long been known that probiotics can be used to maintain intestinal homeostasis and treat a number of gastrointestinal disorders, but the underlying…”
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Transmission dynamics of cholera: Mathematical modeling and control strategies by Sun, Gui-Quan, Xie, Jun-Hui, Huang, Sheng-He, Jin, Zhen, Li, Ming-Tao, Liu, Liqun

“…•We propose a model to describe the transmission of Cholera.•Basic reproduction number of Cholera transmission model are obtained.•Global dynamics are…”
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Cryptococcus neoformans-derived microvesicles enhance the pathogenesis of fungal brain infection by Huang, Sheng-He, Wu, Chun-Hua, Chang, Yun C, Kwon-Chung, Kyung J, Brown, Robert J, Jong, Ambrose

“…Cryptococcal meningoencephalitis is the most common fungal disease in the central nervous system. The mechanisms by which Cryptococcus neoformans invades the…”
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Vimentin, a Novel NF-κB Regulator, Is Required for Meningitic Escherichia coli K1-Induced Pathogen Invasion and PMN Transmigration across the Blood-Brain Barrier by Huang, Sheng-He, Chi, Feng, Peng, Liang, Bo, Tao, Zhang, Bao, Liu, Li-Qun, Wu, Xuedong, Mor-Vaknin, Nirit, Markovitz, David M, Cao, Hong, Zhou, Yan-Hong

“…NF-κB activation, pathogen invasion, polymorphonuclear leukocytes (PMN) transmigration (PMNT) across the blood-brain barrier (BBB) are the pathogenic triad…”
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Repositioning of Memantine as a Potential Novel Therapeutic Agent against Meningitic E. coli-Induced Pathogenicities through Disease-Associated Alpha7 Cholinergic Pathway and RNA Sequencing-Based Transcriptome Analysis of Host Inflammatory Responses by Yu, Jing-Yi, Zhang, Bao, Peng, Liang, Wu, Chun-Hua, Cao, Hong, Zhong, John F, Hoffman, Jill, Huang, Sheng-He

“…Neonatal sepsis and meningitis (NSM) remains a leading cause worldwide of mortality and morbidity in newborn infants despite the availability of antibiotics…”
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Lactobacillus rhamnosus GG supernatant enhance neonatal resistance to systemic Escherichia coli K1 infection by accelerating development of intestinal defense by He, Xiaolong, Zeng, Qing, Puthiyakunnon, Santhosh, Zeng, Zhijie, Yang, Weijun, Qiu, Jiawen, Du, Lei, Boddu, Swapna, Wu, Tongwei, Cai, Danxian, Huang, Sheng-He, Cao, Hong

“…The objective of this study was to determine whether Lactobacillus rhamnosus GG culture supernatant (LCS) has a preventive effect against gut-derived systemic…”
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Alpha7 nicotinic acetylcholine receptor is required for amyloid pathology in brain endothelial cells induced by Glycoprotein 120, methamphetamine and nicotine by Liu, Liqun, Yu, Jingyi, Li, Li, Zhang, Bao, Liu, Lingjuan, Wu, Chun-Hua, Jong, Ambrose, Mao, Ding-An, Huang, Sheng-He

“…One of the most challenging issues in HIV-associated neurocognitive disorders (HAND) caused by HIV-1 virotoxins and drug abuse is the lack of understanding the…”
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Circulating brain microvascular endothelial cells (cBMECs) as potential biomarkers of the blood-brain barrier disorders caused by microbial and non-microbial factors by Huang, Sheng-He, Wang, Lin, Chi, Feng, Wu, Chun-Hua, Cao, Hong, Zhang, Aimin, Jong, Ambrose

“…Despite aggressive research, central nervous system (CNS) disorders, including blood-brain barrier (BBB) injury caused by microbial infection, stroke, abused…”
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Endogenous α7 nAChR Agonist SLURP1 Facilitates Escherichia coli K1 Crossing the Blood-Brain Barrier by He, Xiaolong, Wang, Lei, Liu, Liqun, Gao, Jie, Long, Beiguo, Chi, Feng, Hu, Tongtong, Wan, Yu, Gong, Zelong, Li, Li, Zhen, Peilin, Zhang, Tiesong, Cao, Hong, Huang, Sheng-He

“…Alpha 7 nicotinic acetylcholine receptor (α7 nAChR) is critical for the pathogenesis of ( ) K1 meningitis, a severe central nervous system infection of the…”
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Probiotic Mixture Golden Bifido Prevents Neonatal Escherichia coli K1 Translocation via Enhancing Intestinal Defense by Zeng, Qing, He, Xiaolong, Puthiyakunnon, Santhosh, Xiao, Hansen, Gong, Zelong, Boddu, Swapna, Chen, Lecheng, Tian, Huiwen, Huang, Sheng-He, Cao, Hong

“…( ) K1 sepsis and meningitis is a severe infection characterized by high mortality in neonates. Successful colonization and translocation across the intestinal…”
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Vimentin Inhibits Dengue Virus Type 2 Invasion of the Blood-Brain Barrier by Yu, Jianhai, Li, Xujuan, Zhou, Dongrui, Liu, Xuling, He, Xiaoen, Huang, Sheng-He, Wu, Qinghua, Zhu, Li, Yu, Linzhong, Yao, Jinxiu, Zhang, Bao, Zhao, Wei

“…Dengue virus (DENV) causes dengue fever, which is prevalent in the tropical and subtropical regions, and in recent years, has resulted in several major…”
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Vimentin and PSF act in concert to regulate IbeA+ E. coli K1 induced activation and nuclear translocation of NF-κB in human brain endothelial cells by Chi, Feng, Bo, Tao, Wu, Chun-Hua, Jong, Ambrose, Huang, Sheng-He

“…IbeA-induced NF-κB signaling through its primary receptor vimentin as well as its co-receptor PSF is required for meningitic E. coli K1 penetration and…”
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CD44-mediated monocyte transmigration across Cryptococcus neoformans-infected brain microvascular endothelial cells is enhanced by HIV-1 gp41-I90 ectodomain by He, Xiaolong, Shi, Xiaolu, Puthiyakunnon, Santhosh, Zhang, Like, Zeng, Qing, Li, Yan, Boddu, Swapna, Qiu, Jiawen, Lai, Zhihao, Ma, Chao, Xie, Yulong, Long, Min, Du, Lei, Huang, Sheng-He, Cao, Hong

“…Cryptococcus neoformans (Cn) is an important opportunistic pathogen in the immunocompromised people, including AIDS patients, which leads to fatal cryptococcal…”
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Meningitic Escherichia coli K1 penetration and neutrophil transmigration across the blood-brain barrier are modulated by alpha7 nicotinic receptor by Chi, Feng, Wang, Lin, Zheng, Xueye, Wu, Chun-Hua, Jong, Ambrose, Sheard, Michael A, Shi, Wei, Huang, Sheng-He

“…Alpha7 nicotinic acetylcholine receptor (nAChR), an essential regulator of inflammation, is abundantly expressed in hippocampal neurons, which are vulnerable…”
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Coexpression Network Analysis of Benign and Malignant Phenotypes of SIV-Infected Sooty Mangabey and Rhesus Macaque by Yang, Zhao-Wan, Jiang, Yan-Hua, Ma, Chuang, Silvestri, Guido, Bosinger, Steven E, Li, Bai-Lian, Jong, Ambrose, Zhou, Yan-Hong, Huang, Sheng-He

“…To explore the differences between the extreme SIV infection phenotypes, nonprogression (BEN: benign) to AIDS in sooty mangabeys (SMs) and progression to AIDS…”
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Role of uropathogenic Escherichia coli outer membrane protein T in pathogenesis of urinary tract infection by He, Xiao Long, Wang, Qin, Peng, Liang, Qu, Ya-Rong, Puthiyakunnon, Santhosh, Liu, Xiao-Lu, Hui, Chang Ye, Boddu, Swapna, Cao, Hong, Huang, Sheng-He

“…OmpT is one of the members of the outer membrane protein family that has been identified as a virulence factor in most of the uropathogenic Escherichia coli…”
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Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells by Long, Min, Huang, Sheng-He, Wu, Chun-Hua, Shackleford, Gregory M, Jong, Ambrose

“…Cryptococcus neoformans has a predilection for central nervous system infection. C. neoformans traversal of the blood brain barrier, composed of human brain…”
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Memantine Displays Antimicrobial Activity by Enhancing Escherichia coli Pathogen-Induced Formation of Neutrophil Extracellular Traps by Peng, Liang, Li, Li, He, Xiao-Long, Yu, Jing-Yi, Zeng, Zhi-Jie, Yang, Wei-Jun, Zhang, Bao, Zhang, Tie-Song, Cao, Hong, Huang, Sheng-He, Liu, Li-Qun

“…Bacterial infection remains one of the leading causes of death worldwide due to the continuous rise of multiple antibiotic-resistant bacteria. Focusing solely…”
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Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells by Jong, Ambrose, Wu, Chun-Hua, Shackleford, Gregory M, Kwon-Chung, Kyung J, Chang, Yun C, Chen, Han-Min, Ouyang, Yannan, Huang, Sheng-He

“…Pathogenic yeast Cryptococcus neoformans causes devastating cryptococcal meningoencephalitis. Our previous studies demonstrated that C. neoformans hyaluronic…”
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Involvement of IbeA in Meningitic Escherichia coli K1-Induced Polymorphonuclear Leukocyte Transmigration Across Brain Endothelial Cells by Che, Xiaojuan, Chi, Feng, Wang, Lin, Jong, Timothy D., Wu, Chun-Hua, Wang, Xiaoning, Huang, Sheng-He

“…Transmigration of neutrophil [polymorphonuclear neutrophil (PMN)] across the blood–brain barrier (BBB) is a critical event in the pathogenesis of bacterial…”
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