Search Results - "SHENG, Shijie"

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis by Zhu, Shuomin, Wu, Hailong, Wu, Fangting, Nie, Daotai, Sheng, Shijie, Mo, Yin-Yuan

“…MicroRNAs （miRNAs） are a class of naturally occurring small non-coding RNAs that target protein-coding mRNAs at the post-transcriptional level. Our previous…”
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Metastasis and AKT activation by Qiao, Meng, Sheng, Shijie, Pardee, Arthur B.

“…Metastasis is responsible for 90% of cancer patient deaths. More information is needed about the molecular basis for its potential detection and treatment. The…”
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Trans-boundary aerosol transport during a winter haze episode in China revealed by ground-based Lidar and CALIPSO satellite by Qin, Kai, Wu, Lixin, Wong, Man Sing, Letu, Husi, Hu, Mingyu, Lang, Hongmei, Sheng, Shijie, Teng, Jiyao, Xiao, Xin, Yuan, Limei

“…By employing PM2.5 observation data, ground-based lidar measurements, MODIS and CALIPSO satellite images, meteorological data, and back trajectories analysis,…”
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SMYD5 Controls Heterochromatin and Chromosome Integrity during Embryonic Stem Cell Differentiation by Kidder, Benjamin L, He, Runsheng, Wangsa, Darawalee, Padilla-Nash, Hesed M, Bernardo, M Margarida, Sheng, Shijie, Ried, Thomas, Zhao, Keji

“…Epigenetic regulation of chromatin states is thought to control gene expression programs during lineage specification. However, the roles of repressive histone…”
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Metastasis and AKT activation by Sheng, Shijie, Qiao, Meng, Pardee, Arthur B.

“…Metastasis, responsible for 90% of cancer patient deaths, is an inefficient process because many tumor cells die. The survival of metastatic tumor cells should…”
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Maspin expression patterns differ in the invasive versus lepidic growth pattern of pulmonary adenocarcinoma by Lonardo, Fulvio, Guan, Hui, Dzinic, Sijana, Sheng, Shijie

“…Aims To test whether changes in the subcellular localization of maspin parallel morphological progression in pulmonary adenocarcinoma, we compared its…”
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A Phase II Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Hormone-Refractory Metastatic Prostate Cancer by HEATH, Elisabeth I, HILLMAN, David W, PILI, Roberto, CARDUCCI, Michael A, ERLICHMAN, Charles, LIU, Glenn, VAISHAMPAYAN, Ulka, SHIJIE SHENG, SARKAR, Fazlul, HARPER, Felicity, GASKINS, Melvin, PITOT, Henry C, TAN, Winston, IVY, S. Percy

“…Purpose: 17-Allylamino-17-demethoxygeldanamycin (17-AAG) is a benzoquinone ansamycin antibiotic with antiproliferative activity in several mouse xenograft…”
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An Essential Role of Maspin in Embryogenesis and Tumor Suppression-Response by Zhang, Ming, Hendrix, Mary J C, Pemberton, Philip A, Sakr, Wael A, Sheng, Shijie

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The feasibility of uPA/uPAR-targeting strategies in cancer treatment by Sheng, Shijie

“…Commentary to: Inhibition of Tumor Growth and Metastasis by ATF-Fc, an Engineered Antibody Targeting Urokinase Receptor Xian-wen Hu, Hai-feng Duan, Hai-feng…”
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Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts by Chen, Di, Cui, Qiuzhi Cindy, Yang, Huanjie, Barrea, Raul A, Sarkar, Fazlul H, Sheng, Shijie, Yan, Bing, Reddy, G Prem Veer, Dou, Q Ping

“…Tumor growth and metastasis depend on angiogenesis that requires the cofactor copper. Consistently, high levels of copper have been found in many types of…”
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Maspin differential expression patterns as a potential marker for targeted screening of esophageal adenocarcinoma/gastroesophageal junction adenocarcinoma by Dzinic, Sijana H, Mahdi, Zaid, Bernardo, M Margarida, Vranic, Semir, Beydoun, Haya, Nahra, Nadine, Alijagic, Amra, Harajli, Deanna, Pang, Aaron, Saliganan, Dan M, Rahman, Abid M, Skenderi, Faruk, Hasanbegovic, Berisa, Dyson, Gregory, Beydoun, Rafic, Sheng, Shijie

“…Barrett's esophagus (BE) is a predisposing factor of esophageal adenocarcinoma/gastroesophageal junction adenocarcinoma (ECA/GEJ Aca). BE patients are…”
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An Essential Role of Maspin in Embryogenesis and Tumor Suppression by Dzinic, Sijana H, Bernardo, M Margarida, Li, Xiaohua, Fernandez-Valdivia, Rodrigo, Ho, Ye-Shih, Mi, Qing-Sheng, Bandyopadhyay, Sudeshna, Lonardo, Fulvio, Vranic, Semir, Oliveira, Daniel S M, Bonfil, R Daniel, Dyson, Gregory, Chen, Kang, Omerovic, Almasa, Sheng, Xiujie, Han, Xiang, Wu, Dinghong, Bi, Xinling, Cabaravdic, Dzenana, Jakupovic, Una, Wahba, Marian, Pang, Aaron, Harajli, Deanna, Sakr, Wael A, Sheng, Shijie

“…Maspin (SerpinB5) is an epithelial-specific tumor suppressor gene product that displays context-dependent cellular functions. Maspin-deficient mouse models…”
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Elevated maspin expression is associated with better overall survival in esophageal squamous cell carcinoma (ESCC) by Wang, Yang, Sheng, Shijie, Zhang, Jianzhi, Dzinic, Sijana, Li, Shaolei, Fang, Fang, Wu, Nan, Zheng, Qingfeng, Yang, Yue

“…Tumor suppressor maspin is a differentially regulated gene in the progression of many types of cancer. While the biological function of maspin in blocking…”
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Endogenous inhibition of histone deacetylase 1 by tumor-suppressive maspin by XIAOHUA LI, SHUPING YIN, YONGHONG MENG, SAKR, Wael, SHIJIE SHENG

“…Maspin, a noninhibitory serine protease inhibitor, exerts multifaceted tumor-suppressive effects. Maspin expression is associated with better differentiated…”
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Identification of an intrinsic determinant critical for maspin subcellular localization and function by Dzinic, Sijana H, Kaplun, Alexander, Li, Xiaohua, Bernardo, Margarida, Meng, Yonghong, Dean, Ivory, Krass, David, Stemmer, Paul, Shin, Namhee, Lonardo, Fulvio, Sheng, Shijie

“…Maspin, a multifaceted tumor suppressor, belongs to the serine protease inhibitor superfamily, but only inhibits serine protease-like enzymes such as histone…”
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The natural tumor suppressor protein maspin and potential application in non small cell lung cancer by Lonardo, Fulvio, Li, Xiaohua, Kaplun, Alexander, Soubani, Ayman, Sethi, Seema, Gadgeel, Shirish, Sheng, Shijie

“…The grim prognosis of lung cancer, that has an overall 10-15% survival at 5 years, remains in the US the leading cause of cancer mortality, provides a…”
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Structural insights into neutrophilic migration revealed by the crystal structure of the chemokine receptor CXCR2 in complex with the first PDZ domain of NHERF1 by Lu, Guorong, Wu, Yanning, Jiang, Yuanyuan, Wang, Shuo, Hou, Yuning, Guan, Xiaoqing, Brunzelle, Joseph, Sirinupong, Nualpun, Sheng, Shijie, Li, Chunying, Yang, Zhe

“…Neutrophil plays an essential role in host defense against infection, but uncontrolled neutrophilic infiltration can cause inflammation and severe epithelial…”
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Tumor suppressive maspin and epithelial homeostasis by Lockett, Jaron, Yin, Shuping, Li, Xiaohua, Meng, Yonghong, Sheng, Shijie

“…Maspin is a 42‐kDa novel serine protease inhibitor (serpin) with multifaceted tumor suppressive activities. To date, the consensus that maspin expression…”
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Maspin sensitizes prostate cancer cells to doxazosin-induced apoptosis by TAHMATZOPOULOS, Anastasios, SHIJIE SHENG, KYPRIANOU, Natasha

“…Maspin is a mammary serine protease inhibitor or serpin with tumor suppressive and antiangiogenic activity that inhibits tumor motility, invasion and…”
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The promise and challenge toward the clinical application of maspin in cancer by Sheng, Shijie

“…Since the identification of the human maspin gene, a decade of extensive research revealed the promise of maspin both as a valuable molecular marker for the…”
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