Search Results - "SHEN, Jeanne"

Deep learning model for the prediction of microsatellite instability in colorectal cancer: a diagnostic study by Yamashita, Rikiya, Long, Jin, Longacre, Teri, Peng, Lan, Berry, Gerald, Martin, Brock, Higgins, John, Rubin, Daniel L, Shen, Jeanne

“…Detecting microsatellite instability (MSI) in colorectal cancer is crucial for clinical decision making, as it identifies patients with differential treatment…”
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Microsatellite Instability and BRAF Mutation Testing in Colorectal Cancer Prognostication by LOCHHEAD, Paul, KUCHIBA, Aya, FUCHS, Charles S, OGINO, Shuji, IMAMURA, Yu, XIAOYUN LIAO, YAMAUCHI, Mai, NISHIHARA, Reiko, ZHI RONG QIAN, MORIKAWA, Teppei, SHEN, Jeanne, MEYERHARDT, Jeffrey A

“…BRAF mutation in colorectal cancer is associated with microsatellite instability (MSI) through its relationship with high-level CpG island methylator phenotype…”
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Deep learning predicts postsurgical recurrence of hepatocellular carcinoma from digital histopathologic images by Yamashita, Rikiya, Long, Jin, Saleem, Atif, Rubin, Daniel L., Shen, Jeanne

“…Recurrence risk stratification of patients undergoing primary surgical resection for hepatocellular carcinoma (HCC) is an area of active investigation, and…”
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The persistent problem of new-onset postoperative atrial fibrillation: A single-institution experience over two decades by Shen, Jeanne, BS, Lall, Shelly, MD, Zheng, Victoria, MD, Buckley, Patricia, RHIT, Damiano, Ralph J., MD, Schuessler, Richard B., PhD

“…Objective Postoperative atrial fibrillation is the most common complication after cardiac surgery. A variety of postoperative atrial fibrillation risk factors…”
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A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis by Brack, Andrew S, Conboy, Irina M, Conboy, Michael J, Shen, Jeanne, Rando, Thomas A

“…The temporal switch from progenitor cell proliferation to differentiation is essential for effective adult tissue repair. We previously reported the critical…”
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SWI/SNF component ARID1A restrains pancreatic neoplasia formation by Wang, Sam C, Nassour, Ibrahim, Xiao, Shu, Zhang, Shuyuan, Luo, Xin, Lee, Jeon, Li, Lin, Sun, Xuxu, Nguyen, Liem H, Chuang, Jen-Chieh, Peng, Lan, Daigle, Scott, Shen, Jeanne, Zhu, Hao

“…is commonly mutated in pancreatic ductal adenocarcinoma (PDAC), but the functional effects of mutations in the pancreas are unclear. Understanding the…”
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Pepsinogens and Gastrin Demonstrate Low Discrimination for Gastric Precancerous Lesions in a Multi-Ethnic United States Cohort by Huang, Robert J., Park, Sungho, Shen, Jeanne, Longacre, Teri, Ji, Hanlee, Hwang, Joo Ha

“…Early identification of gastric precancerous lesions, including atrophic gastritis (AG) and intestinal metaplasia (IM), may improve gastric cancer detection…”
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Impact of a deep learning assistant on the histopathologic classification of liver cancer by Kiani, Amirhossein, Uyumazturk, Bora, Rajpurkar, Pranav, Wang, Alex, Gao, Rebecca, Jones, Erik, Yu, Yifan, Langlotz, Curtis P., Ball, Robyn L., Montine, Thomas J., Martin, Brock A., Berry, Gerald J., Ozawa, Michael G., Hazard, Florette K., Brown, Ryanne A., Chen, Simon B., Wood, Mona, Allard, Libby S., Ylagan, Lourdes, Ng, Andrew Y., Shen, Jeanne

“…Artificial intelligence (AI) algorithms continue to rival human performance on a variety of clinical tasks, while their actual impact on human diagnosticians,…”
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Continuity of transcriptomes among colorectal cancer subtypes based on meta-analysis by Ma, Siyuan, Ogino, Shuji, Parsana, Princy, Nishihara, Reiko, Qian, Zhirong, Shen, Jeanne, Mima, Kosuke, Masugi, Yohei, Cao, Yin, Nowak, Jonathan A, Shima, Kaori, Hoshida, Yujin, Giovannucci, Edward L, Gala, Manish K, Chan, Andrew T, Fuchs, Charles S, Parmigiani, Giovanni, Huttenhower, Curtis, Waldron, Levi

“…Previous approaches to defining subtypes of colorectal carcinoma (CRC) and other cancers based on transcriptomes have assumed the existence of discrete…”
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Enteric Glia Play a Critical Role in Promoting the Development of Colorectal Cancer by Yuan, Robert, Bhattacharya, Nupur, Kenkel, Justin A, Shen, Jeanne, DiMaio, Michael A, Bagchi, Sreya, Prestwood, Tyler R, Habtezion, Aida, Engleman, Edgar G

“…Enteric glia are a distinct population of peripheral glial cells in the enteric nervous system that regulate intestinal homeostasis, epithelial barrier…”
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Clinical, pathologic, and outcome study of hyperplastic and sessile serrated polyps in inflammatory bowel disease by Shen, Jeanne, MD, Gibson, Joanna A., MD, PhD, Schulte, Stephanie, MD, Khurana, Hema, MD, Farraye, Francis A., MD, MSc, Levine, Jonathan, MD, Burakoff, Robert, MD, MPH, Cerda, Sandra, MD, Qazi, Taha, MD, Hamilton, Matthew, MD, Srivastava, Amitabh, MD, Odze, Robert D., MD, FRCPC

“…Summary There is evidence that some cancers in patients with inflammatory bowel disease (IBD) develop via the serrated pathway of carcinogenesis. This study…”
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Predicting lymph node metastasis from primary tumor histology and clinicopathologic factors in colorectal cancer using deep learning by Krogue, Justin D., Azizi, Shekoofeh, Tan, Fraser, Flament-Auvigne, Isabelle, Brown, Trissia, Plass, Markus, Reihs, Robert, Müller, Heimo, Zatloukal, Kurt, Richeson, Pema, Corrado, Greg S., Peng, Lily H., Mermel, Craig H., Liu, Yun, Chen, Po-Hsuan Cameron, Gombar, Saurabh, Montine, Thomas, Shen, Jeanne, Steiner, David F., Wulczyn, Ellery

“…Background Presence of lymph node metastasis (LNM) influences prognosis and clinical decision-making in colorectal cancer. However, detection of LNM is…”
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Inflamed immune phenotype predicts favorable clinical outcomes of immune checkpoint inhibitor therapy across multiple cancer types by Shen, Jeanne, Choi, Yoon-La, Lee, Taebum, Kim, Hyojin, Chae, Young Kwang, Dulken, Ben W, Bogdan, Stephanie, Huang, Maggie, Fisher, George A, Park, Sehhoon, Lee, Se-Hoon, Hwang, Jun-Eul, Chung, Jin-Haeng, Kim, Leeseul, Song, Heon, Pereira, Sergio, Shin, Seunghwan, Lim, Yoojoo, Ahn, Chang Ho, Kim, Seulki, Oum, Chiyoon, Kim, Sukjun, Park, Gahee, Song, Sanghoon, Jung, Wonkyung, Kim, Seokhwi, Bang, Yung-Jue, Mok, Tony S K, Ali, Siraj M., Ock, Chan-Young

“…BackgroundThe inflamed immune phenotype (IIP), defined by enrichment of tumor-infiltrating lymphocytes (TILs) within intratumoral areas, is a promising…”
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Prediction of immunochemotherapy response for diffuse large B‐cell lymphoma using artificial intelligence digital pathology by Lee, Jeong Hoon, Song, Ga‐Young, Lee, Jonghyun, Kang, Sae‐Ryung, Moon, Kyoung Min, Choi, Yoo‐Duk, Shen, Jeanne, Noh, Myung‐Giun, Yang, Deok‐Hwan

“…Diffuse large B‐cell lymphoma (DLBCL) is a heterogeneous and prevalent subtype of aggressive non‐Hodgkin lymphoma that poses diagnostic and prognostic…”
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The surgical treatment of atrial fibrillation by Shen, Jeanne, BS, Bailey, Marci S., RN, MSN, Damiano, Ralph J., MD

“…For two decades, the cut-and-sew Cox-maze III procedure was the gold standard for the surgical treatment of atrial fibrillation (AF) and has proven to be…”
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Learning Domain-Agnostic Visual Representation for Computational Pathology Using Medically-Irrelevant Style Transfer Augmentation by Yamashita, Rikiya, Long, Jin, Banda, Snikitha, Shen, Jeanne, Rubin, Daniel L.

“…Suboptimal generalization of machine learning models on unseen data is a key challenge which hampers the clinical applicability of such models to medical…”
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In the Thick of It: The Many Faces of Collagenous Gastritis by Singh, Sundeep, Jing, Emily, Shen, Jeanne

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Single-cell analyses define a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancer by Becker, Winston R., Nevins, Stephanie A., Chen, Derek C., Chiu, Roxanne, Horning, Aaron M., Guha, Tuhin K., Laquindanum, Rozelle, Mills, Meredith, Chaib, Hassan, Ladabaum, Uri, Longacre, Teri, Shen, Jeanne, Esplin, Edward D., Kundaje, Anshul, Ford, James M., Curtis, Christina, Snyder, Michael P., Greenleaf, William J.

“…To chart cell composition and cell state changes that occur during the transformation of healthy colon to precancerous adenomas to colorectal cancer (CRC), we…”
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Clinical, Pathologic, and Biologic Features Associated with BRAF Mutations in Non―Small Cell Lung Cancer by CARDARELLA, Stephanie, OGINO, Atsuko, NISHINO, Mizuki, BUTANEY, Mohit, SHEN, Jeanne, LYDON, Christine, YEAP, Beow Y, SHOLL, Lynette M, JOHNSON, Bruce E, JÄNNE, Pasi A

“…BRAF mutations are found in a subset of non-small cell lung cancers (NSCLC). We examined the clinical characteristics and treatment outcomes of patients with…”
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Development and Validation of a Machine Learning Model for Detection and Classification of Tertiary Lymphoid Structures in Gastrointestinal Cancers by Li, Zhe, Jiang, Yuming, Li, Bailiang, Han, Zhen, Shen, Jeanne, Xia, Yong, Li, Ruijiang

“…Tertiary lymphoid structures (TLSs) are associated with a favorable prognosis and improved response to cancer immunotherapy. The current approach for…”
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