Search Results - "SHEARMAN, Amanda M"

Genetic Loci Influencing Lung Function . A Genomewide Scan in the Framingham Study by JOOST, OSCAR, WILK, JEMMA B, ADRIENNE CUPPLES, L, HARMON, MICHAEL, SHEARMAN, AMANDA M, BALDWIN, CLINTON T, O'CONNOR, GEORGE T, MYERS, RICHARD H, GOTTLIEB, DANIEL J

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Genome-wide linkage analyses and candidate gene fine mapping for HDL₃ cholesterol: the Framingham Study by Yang, Qiong, Lai, Chao-Qiang, Parnell, Laurence, Cupples, L. Adrienne, Adiconis, Xian, Zhu, Yueping, Wilson, Peter W. F, Housman, David E, Shearman, Amanda M, D'Agostino, Ralph B, Ordovas, Jose M

“…High density lipoprotein cholesterol (HDL-C) is inversely associated with coronary heart disease and has a genetic component; however, linkage to HDL-C is not…”
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Association Between Estrogen Receptor α Gene Variation and Cardiovascular Disease by Shearman, Amanda M, Cupples, L. Adrienne, Demissie, Serkalem, Peter, Inga, Schmid, Christopher H, Karas, Richard H, Mendelsohn, Michael E, Housman, David E, Levy, Daniel

“…CONTEXT: Estrogen and related hormone therapies activate estrogen receptors, which in turn regulate genes for several cardiovascular disease (CVD) risk…”
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Estrogen receptor alpha gene variation and the risk of stroke by Shearman, Amanda M, Cooper, Jackie A, Kotwinski, Paul J, Humphries, Steve E, Mendelsohn, Michael E, Housman, David E, Miller, George J

“…Estrogen receptor alpha (ESR1) gene variation is associated with a range of important estrogen-dependent characteristics, including responses of lipid profile…”
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Oestrogen receptor genetics: a needle that cuts through many haystacks? by Shearman, Amanda M

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Variation in estrogen-related genes and cross-sectional and longitudinal blood pressure in the Framingham Heart Study by Peter, Inga, Shearman, Amanda M, Zucker, Deborah R, Schmid, Christopher H, Demissie, Serkalem, Cupples, L Adrienne, Larson, Martin G, Vasan, Ramachandran S, D'Agostino, Ralph B, Karas, Richard H, Mendelsohn, Michael E, Housman, David E, Levy, Daniel

“…To examine the association between variation in estrogen-related genes and cross-sectional and longitudinal blood pressure in men and women. In 1780 unrelated…”
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Estrogen Receptor α Gene Variation Is Associated With Risk of Myocardial Infarction in More Than Seven Thousand Men From Five Cohorts by Shearman, Amanda M, Cooper, Jackie A, Kotwinski, Paul J, Miller, George J, Humphries, Steve E, Ardlie, Kristin G, Jordan, Barbara, Irenze, Kathryn, Lunetta, Kathryn L, Schuit, Stephanie C.E, Uitterlinden, André G, Pols, Huibert A.P, Demissie, Serkalem, Cupples, L Adrienne, Mendelsohn, Michael E, Levy, Daniel, Housman, David E

“…Understanding the mechanisms by which estrogens affect cardiovascular disease risk, including the role of variation in the gene for estrogen receptor α (ESR1),…”
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The Relationship of Estrogen Receptor-α and -β Genes with Osteoarthritis of the Hand by WISE, Barton L, DEMISSIE, Serkalem, CUPPLES, L. Adrienne, FELSON, David T, MEI YANG, SHEARMAN, Amanda M, ALIABADI, Piran, HUNTER, David J

“…We examined reported associations between radiographic hand osteoarthritis (OA) and single-nucleotide polymorphisms (SNP) in 2 candidate genes associated with…”
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Estrogen Receptor β Polymorphisms Are Associated With Bone Mass in Women and Men: The Framingham Study by Shearman, Amanda M, Karasik, David, Gruenthal, Kristen M, Demissie, Serkalem, Cupples, L Adrienne, Housman, David E, Kiel, Douglas P

“…ESR2 is expressed in bone cells, yet few studies have tested its variation for association with BMD, an important determinant of osteoporotic fractures. This…”
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Sex-Specific Association between Estrogen Receptor-α Gene Variation and Measures of Adiposity: The Framingham Heart Study by Fox, Caroline S., Yang, Qiong, Cupples, L. Adrienne, Guo, Chao-Yu, Atwood, Larry D., Murabito, Joanne M., Levy, Daniel, Mendelsohn, Michael E., Housman, David E., Shearman, Amanda M.

“…Background: Polymorphisms in estrogen receptor-α (ESR1) may be associated with variation in body mass index and waist circumference. However, most prior…”
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Association of Estrogen Receptor β Gene Polymorphisms With Left Ventricular Mass and Wall Thickness in Women by Peter, Inga, Shearman, Amanda M., Vasan, Ramachandran S., Zucker, Deborah R., Schmid, Christopher H., Demissie, Serkalem, Cupples, L. Adrienne, Kuvin, Jeffrey T., Karas, Richard H., Mendelsohn, Michael E., Housman, David E., Benjamin, Emelia J.

“…Left ventricular (LV) hypertrophy is a significant risk factor for cardiovascular disease. Given sex-based differences in cardiac structure and remodeling, we…”
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Estrogen receptor-α variants are associated with lipoprotein size distribution and particle levels in women: The Framingham Heart Study by Demissie, Serkalem, Cupples, L. Adrienne, Shearman, Amanda M., Gruenthal, Kristen M., Peter, Inga, Schmid, Christopher H., Karas, Richard H., Housman, David E., Mendelsohn, Michael E., Ordovas, Jose M.

“…Plasma lipid profile is affected by endogenous estrogen levels and hormone replacement therapy (HRT). As plasma lipid concentrations have a significant…”
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Age-Related Changes in Echocardiographic Measurements: Association With Variation in the Estrogen Receptor-α Gene by Peter, Inga, Huggins, Gordon S, Shearman, Amanda M, Pollak, Arthur, Schmid, Christopher H, Cupples, L Adrienne, Demissie, Serkalem, Patten, Richard D, Karas, Richard H, Housman, David E, Mendelsohn, Michael E, Vasan, Ramachandran S, Benjamin, Emelia J

“…Left ventricular (LV) mass and other LV measures have been shown to be heritable. In this study we hypothesized that functional variation in the gene coding…”
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Tobacco smoking, estrogen receptor α gene variation and small low density lipoprotein level by Shearman, Amanda M., Demissie, Serkalem, Cupples, L. Adrienne, Peter, Inga, Schmid, Christopher H., Ordovas, Jose M., Mendelsohn, Michael E., Housman, David E.

“…High levels of small low density lipoprotein (LDL) particles are a major risk factor for cardiovascular morbidity and mortality. Both estrogens and smoking,…”
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Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: a genome-wide scan in the Framingham study by Shearman, A M, Ordovas, J M, Cupples, L A, Schaefer, E J, Harmon, M D, Shao, Y, Keen, J D, DeStefano, A L, Joost, O, Wilson, P W, Housman, D E, Myers, R H

“…Some studies show that plasma triglyceride (TG) levels are a significant independent risk factor for cardiovascular disease (CVD). TG levels are inversely…”
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Fine mapping of the Schnyder's crystalline corneal dystrophy locus by THEENDAKARA, Veena, TROMP, Gerard, TERVO, Timo M, HENN, Wolfram, DENNIGER, Elke, KRAUSE, Matthias, KOKSAL, Murat, KARGI, Sebnem, UGURBAS, Suat H, LATVALA, Terho, SHEARMAN, Amanda M, WEISS, Jayne S, KUIVANIEMI, Helena, WHITE, Peter S, PANCHAL, Seema, COX, Jennifer, WINTERS, R. Scott, RIEBELING, Petra, TOST, Frank, HOELTZENBEIN, Maria

“…Schnyder's crystalline corneal dystrophy (SCCD) is a rare autosomal dominant eye disease with a spectrum of clinical manifestations that may include bilateral…”
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Genetic linkage of familial expansile osteolysis to chromosome 18q by Hughes, A E, Shearman, A M, Weber, J L, Barr, R J, Wallace, R G, Osterberg, P H, Nevin, N C, Mollan, R A

“…Familial expansile osteolysis is a rare bone dysplasia which is transmitted as an autosomal dominant trait in a large kindred in Northern Ireland. The gene…”
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Hormone receptor polymorphisms by Shearman, Amanda M

“…This chapter describes some general concepts about genetic polymorphisms and association studies, and then provides examples of how polymorphisms in the…”
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Oestrogen receptor genetics: a needle that cuts through many haystacks?The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology by Shearman, Amanda M.

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The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP96 and class I homeoprotein HOXA9 by Stanton, Vincent P, Williams, Amy J, Rowley, Janet, Kwong, Yok L, Housman, David E, Shearman, Amanda M, Katz, Fay, Becher, Reinhard, Collins, Tucker, Toyama, Keisuke, Morris, Christine, Borrow, Julian, Dubé, Ian, Ohyashiki, Kazuma

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