Search Results - "SHAW, C. A"

Aluminum in the central nervous system (CNS): toxicity in humans and animals, vaccine adjuvants, and autoimmunity by Shaw, C. A., Tomljenovic, L.

“…We have examined the neurotoxicity of aluminum in humans and animals under various conditions, following different routes of administration, and provide an…”
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Aluminum vaccine adjuvants: are they safe? by Tomljenovic, L, Shaw, C A

“…Aluminum is an experimentally demonstrated neurotoxin and the most commonly used vaccine adjuvant. Despite almost 90 years of widespread use of aluminum…”
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Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations by Tomljenovic, L, Shaw, CA

“…Immune challenges during early development, including those vaccine-induced, can lead to permanent detrimental alterations of the brain and immune function…”
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Structural Controls on Crustal Fluid Circulation and Hot Spring Geochemistry Above a Flat‐Slab Subduction Zone, Peru by B. E. Scott, D. L. Newell, M. J. Jessup, T. A. Grambling, C. A. Shaw

“…Abstract Hot spring geochemistry from the Cordillera Blanca and Cordillera Huayhuash, Peru, reveal the influence of crustal‐scale structures on geothermal…”
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The natural history of Noonan syndrome: a long-term follow-up study by Shaw, A C, Kalidas, K, Crosby, A H, Jeffery, S, Patton, M A

“…Objective: To define better the adult phenotype and natural history of Noonan syndrome. Design: A prospective observational study of a large cohort. Results:…”
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Olfactory copy number association with age at onset of Alzheimer disease by SHAW, C. A, LI, Y, DOODY, R. S, SZIGETI, K, WISZNIEWSKA, J, CHASSE, S, ZAIDI, S. N. Y, JIN, W, DAWSON, B, WILHELMSEN, K, LUPSKI, J. R, BELMONT, J. W

“…Copy number variants (CNVs) have been recognized as a source of genetic variation that contributes to disease phenotypes. Alzheimer disease (AD) has high…”
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LACK OF CEREBRAL BMAA IN HUMAN CEREBRAL CORTEX by SNYDER, L. R, CRUZ-AGUADO, R, SADILEK, M, GALASKO, D, SHAW, C. A, MONTINE, T. J

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Vaccine‐associated varicella and rubella infections in severe combined immunodeficiency with isolated CD4 lymphocytopenia and mutations in IL7R detected by tandem whole exome sequencing and chromosomal microarray by Bayer, D. K., Martinez, C. A., Sorte, H. S., Forbes, L. R., Demmler‐Harrison, G. J., Hanson, I. C., Pearson, N. M., Noroski, L. M., Zaki, S. R., Bellini, W. J., Leduc, M. S., Yang, Y., Eng, C. M., Patel, A., Rodningen, O. K., Muzny, D. M., Gibbs, R. A., Campbell, I. M., Shaw, C. A., Baker, M. W., Zhang, V., Lupski, J. R., Orange, J. S., Seeborg, F. O., Stray‐Pedersen, A.

“…Summary In areas without newborn screening for severe combined immunodeficiency (SCID), disease‐defining infections may lead to diagnosis, and in some cases,…”
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Glutathione and Signal Transduction in the Mammalian CNS by Janáky, R., Ogita, K., Pasqualotto, B. A., Bains, J. S., Oja, S. S., Yoneda, Y., Shaw, C. A.

“…: The tripeptide glutathione (GSH) has been thoroughly investigated in relation to its role as antioxidant and free radical scavenger. In recent years, novel…”
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Hypovitaminosis D in Medical Inpatients by Thomas, Melissa K, Lloyd-Jones, Donald M, Thadhani, Ravi I, Shaw, Albert C, Deraska, Donald J, Kitch, Barrett T, Vamvakas, Eleftherios C, Dick, Ian M, Prince, Richard L, Finkelstein, Joel S

“…Vitamin D deficiency is a risk factor for osteopenia and bone fractures. 1 – 5 In ambulatory elderly people whose average serum concentration of…”
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Chronic Exposure to Dietary Sterol Glucosides is Neurotoxic to Motor Neurons and Induces an ALS–PDC Phenotype by Tabata, R. C., Wilson, J. M. B., Ly, P., Zwiegers, P., Kwok, D., Van Kampen, J. M., Cashman, N., Shaw, C. A.

“…Epidemiological studies of the Guamanian variants of amyotrophic lateral sclerosis (ALS) and parkinsonism, amyotrophic lateral sclerosis–parkinsonism dementia…”
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Dominant versus recessive traits conveyed by allelic mutations - to what extent is nonsense-mediated decay involved? by Ben-Shachar, S, Khajavi, M, Withers, MA, Shaw, CA, Van Bokhoven, H, Brunner, HG, Lupski, JR

“…Mutations in ROR2, encoding a receptor tyrosine kinase, can cause autosomal recessive Robinow syndrome (RRS), a severe skeletal dysplasia with limb shortening,…”
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Comparative genomic hybridisation using a proximal 17p BAC/PAC array detects rearrangements responsible for four genomic disorders by Shaw, C J, Shaw, C A, Yu, W, Stankiewicz, P, White, L D, Beaudet, A L, Lupski, J R

“…Background: Proximal chromosome 17p is a region rich in low copy repeats (LCRs) and prone to chromosomal rearrangements. Four genomic disorders map within the…”
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The Medicalization of Birth and Midwifery as Resistance by Shaw, Jessica C. A.

“…Through the medicalization of women's bodies, the credibility and traditional knowledge of midwives and healers was forcibly lost. Northern Aboriginal…”
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Administration of aluminium to neonatal mice in vaccine-relevant amounts is associated with adverse long term neurological outcomes by Shaw, C.A., Li, Y., Tomljenovic, L.

“…Our previous ecological studies of autism spectrum disorder (ASD) has demonstrated a correlation between increasing ASD rates and aluminium (Al) adjuvants in…”
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Taurine release in developing mouse hippocampus is modulated by glutathione and glutathione derivatives by Janáky, R, Shaw, C. A, Oja, S. S, Saransaari, P

“…Glutathione (reduced form GSH and oxidized form GSSG) constitutes an important defense against oxidative stress in the brain, and taurine is an inhibitory…”
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Twelve‐month risk of thromboembolic events in COVID‐19 hospital survivors in Scotland by Farrell, J., Docherty, A. B., Thorpe, M. G., Shaw, C. A., Harrison, E. M., Lone, N. I.

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Analysis of neurological disease in four dimensions: insight from ALS-PDC epidemiology and animal models by Shaw, C.A, Wilson, J.M.B

“…The causal factor(s) responsible for sporadic neurological diseases are unknown and the stages of disease progression remain undefined and poorly understood…”
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The protease‐activated receptor 4 Ala120Thr variant alters platelet responsiveness to low‐dose thrombin and protease‐activated receptor 4 desensitization, and is blocked by non‐competitive P2Y12 inhibition by Whitley, M. J., Henke, D. M., Ghazi, A., Nieman, M., Stoller, M., Simon, L. M., Chen, E., Vesci, J., Holinstat, M., McKenzie, S. E., Shaw, C. A., Edelstein, L. C., Bray, P. F.

“…Essentials The rs773902 SNP results in differences in platelet protease‐activated receptor (PAR4) function. The functional consequences of rs773902 were…”
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Isolation of various forms of sterol β‐d‐glucoside from the seed of Cycas circinalis: neurotoxicity and implications for ALS‐parkinsonism dementia complex by Khabazian, I., Bains, J. S., Williams, D. E., Cheung, J., Wilson, J. M. B., Pasqualotto, B. A., Pelech, S. L., Andersen, R. J., Wang, Y.‐T., Liu, L., Nagai, A., Kim, S. U., Craig, U‐K., Shaw, C. A.

“…The factors responsible for ALS‐parkinsonism dementia complex (ALS‐PDC), the unique neurological disorder of Guam, remain unresolved, but identification of…”
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