Search Results - "SHAVIT, Yehuda"

Genetic impairment of interleukin-1 signaling attenuates neuropathic pain, autotomy, and spontaneous ectopic neuronal activity, following nerve injury in mice by Wolf, Gilly, Gabay, Eran, Tal, Michael, Yirmiya, Raz, Shavit, Yehuda

“…Peripheral nerve injury may lead to neuropathic pain, which is often associated with mechanical and thermal allodynia, ectopic discharge of from injured nerves…”
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The Effects of Postoperative Pain Management on Immune Response to Surgery by Beilin, Benzion, Shavit, Yehuda, Trabekin, Evelyn, Mordashev, Boris, Mayburd, Eduard, Zeidel, Alexander, Bessler, Hanna

“…Surgery is associated with immune alterations, which are the combined result of tissue damage, anesthesia, postoperative pain, and psychological stress. In the…”
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Interleukin-1 signaling is required for induction and maintenance of postoperative incisional pain: Genetic and pharmacological studies in mice by Wolf, Gilly, Livshits, Dina, Beilin, Benzion, Yirmiya, Raz, Shavit, Yehuda

“…Abstract Postoperative incisional pain is characterized by persistent acute pain in the area of the cut, and is associated with release of proinflammatory…”
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Effects of preemptive analgesia on pain and cytokine production in the postoperative period by BEILIN, Benzion, BESSLER, Hanna, MAYBURD, Eduard, SMIRNOV, Genady, DEKEL, Arie, YARDENI, Israel, SHAVIT, Yehuda

“…The postoperative period is associated with increased production of proinflammatory cytokines, which are known to augment pain sensitivity, among other…”
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Impairment of interleukin-1 (IL-1) signaling reduces basal pain sensitivity in mice: genetic, pharmacological and developmental aspects by Wolf, Gilly, Yirmiya, Raz, Goshen, Inbal, Iverfeldt, Kerstin, Holmlund, Linda, Takeda, Kiyoshi, Shavit, Yehuda

“…The cytokine interleukin-1 (IL-1) has been implicated in modulation of pain perception under various inflammatory conditions. The present study examined the…”
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Effects of Mild perioperative hypothermia on cellular immune responses by BEILIN, B, SHAVIT, Y, RAZUMOVSKY, J, WOLLOCH, Y, ZEIDEL, A, BESSLER, H

“…Unintentional perioperative hypothermia is a common complication of anesthesia and surgery associated with adverse effects on several systems, including…”
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Does Intraoperative Ketamine Attenuate Inflammatory Reactivity Following Surgery? A Systematic Review and Meta-Analysis by Dale, Ola, Somogyi, Andrew A., Li, Yibai, Sullivan, Thomas, Shavit, Yehuda

“…Reports regarding the ability of the anesthetic drug ketamine to attenuate the inflammatory response to surgery are conflicting. In this systematic review we…”
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Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia by Hutchinson, Mark R, Shavit, Yehuda, Grace, Peter M, Rice, Kenner C, Maier, Steven F, Watkins, Linda R

“…Vastly stimulated by the discovery of opioid receptors in the early 1970s, preclinical and clinical research was directed at the study of stereoselective…”
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The transition from naïve to primed nociceptive state: A novel wind-up protocol in mice by Ziv, Nadav Y., Tal, Michael, Shavit, Yehuda

“…Wind-up (WU) is a progressive, frequency-dependent facilitation of spinal cord neurons in response to repetitive nociceptive stimulation of constant intensity…”
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Intrinsic Mechanisms of Pain Inhibition: Activation by Stress by Terman, Gregory W., Shavit, Yehuda, Lewis, James W., Cannon, J. Timothy, Liebeskind, John C.

“…Portions of the brain stem seem normally to inhibit pain. In man and laboratory animals these brain areas and pathways from them to spinal sensory circuits can…”
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Interleukin-1 antagonizes morphine analgesia and underlies morphine tolerance by Shavit, Yehuda, Wolf, Gilly, Goshen, Inbal, Livshits, Dina, Yirmiya, Raz

“…Pain sensitivity reflects a balance between pain facilitatory and inhibitory systems. To characterize the relationships between these systems we examined the…”
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Opioid Peptides Mediate the Suppressive Effect of Stress on Natural Killer Cell Cytotoxicity by Shavit, Yehuda, Lewis, James W., Terman, Gregory W., Gale, Robert Peter, Liebeskind, John C.

“…The cytotoxic activity of natural killer cells was investigated in rats subjected to one of two inescapable footshock stress paradigms, both of which induce…”
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Chronic blockade of interleukin-1 (IL-1) prevents and attenuates neuropathic pain behavior and spontaneous ectopic neuronal activity following nerve injury by Gabay, Eran, Wolf, Gilly, Shavit, Yehuda, Yirmiya, Raz, Tal, Michael

“…Abstract Neuropathic pain is a chronic pain state resulting from peripheral nerve injury, characterized by hyperalgesia and allodynia. We have reported that…”
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Postoperative pain management and proinflammatory cytokines: animal and human studies by Shavit, Yehuda, Fridel, Keren, Beilin, Benzion

“…The postoperative period is associated with neuroendocrine, metabolic, and immune alterations, which are the combined result of tissue damage, anesthesia,…”
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Effects of fentanyl on natural killer cell activity and on resistance to tumor metastasis in rats. Dose and timing study by Shavit, Yehuda, Ben-Eliyahu, Shamgar, Zeidel, Alexander, Beilin, Benzion

“…Opiates, which serve an integral role in anesthesia, suppress immune function, particularly natural killer cell cytotoxicity (NKCC). NK cells play an important…”
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Effects of Anesthesia Based on Large Versus Small Doses of Fentanyl on Natural Killer Cell Cytotoxicity in the Perioperative Period by Beilin, Benzion, Shavit, Yehuda, Hart, Jacob, Mordashov, Boris, Cohn, Sergiu, Notti, Ida, Bessler, Hanna

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IL-1β signaling is required for mechanical allodynia induced by nerve injury and for the ensuing reduction in spinal cord neuronal GRK2 by Kleibeuker, Wendy, Gabay, Eran, Kavelaars, Annemieke, Zijlstra, Jitske, Wolf, Gilly, Ziv, Nadav, Yirmiya, Raz, Shavit, Yehuda, Tal, Michael, Heijnen, Cobi J

“…Abstract Many neurotransmitters involved in pain perception transmit signals via G protein-coupled receptors (GPCRs). GPCR kinase 2 (GRK2) regulates…”
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Neuropsychological functioning in major depression and responsiveness to selective serotonin reuptake inhibitors antidepressants by Kampf-Sherf, Orli, Zlotogorski, Zoli, Gilboa, Asaf, Speedie, Lynn, Lereya, Jossef, Rosca, Paula, Shavit, Yehuda

“…Background: Only two thirds of patients with major depression (MD) respond to antidepressants. Thus, far applicable predictors of responsiveness to selective…”
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Comparison of postoperative pain management techniques on endocrine response to surgery: A randomised controlled trial by Yardeni, Israel Z, Shavit, Yehuda, Bessler, Hanna, Mayburd, Eduard, Grinevich, Galina, Beilin, Benzion

“…Abstract The present study compared three postoperative pain management techniques in patients undergoing lower abdominal surgery: intermittent opiate regimen…”
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Cytokines and cholinergic signals co-modulate surgical stress-induced changes in mood and memory by Shapira-Lichter, Irit, Beilin, Benzion, Ofek, Keren, Bessler, Hanna, Gruberger, Michal, Shavit, Yehuda, Seror, Dan, Grinevich, Galina, Posner, Eldad, Reichenberg, Abraham, Soreq, Hermona, Yirmiya, Raz

“…Abstract Inflammatory cytokines and the cholinergic system have been implicated in the effects of stressors on mood and memory; however, the underlying…”
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