Search Results - "SHARON ZHANG"

Ptpn11/Shp2 Acts as a Tumor Suppressor in Hepatocellular Carcinogenesis by Bard-Chapeau, Emilie A., Li, Shuangwei, Ding, Jin, Zhang, Sharon S., Zhu, Helen H., Princen, Frederic, Fang, Diane D., Han, Tao, Bailly-Maitre, Beatrice, Poli, Valeria, Varki, Nissi M., Wang, Hongyang, Feng, Gen-Sheng

“…The human gene Ptpn11, which encodes the tyrosine phosphatase Shp2, may act as a proto-oncogene because dominantly activating mutations have been detected in…”
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Diphenyl Phosphate-Induced Toxicity During Embryonic Development by Mitchell, Constance A, Reddam, Aalekhya, Dasgupta, Subham, Zhang, Sharon, Stapleton, Heather M, Volz, David C

“…Diphenyl phosphate (DPHP) is an aryl phosphate ester (APE) used as an industrial catalyst and chemical additive and is the primary metabolite of flame…”
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Triphenyl phosphate-induced pericardial edema in zebrafish embryos is dependent on the ionic strength of exposure media by Wiegand, Jenna, Avila-Barnard, Sarah, Nemarugommula, Charvita, Lyons, David, Zhang, Sharon, Stapleton, Heather M., Volz, David C.

“…[Display omitted] •Ionic strength of exposure media influences the severity of pericardial edema formation.•D-Mannitol does not impact TPHP uptake in embryonic…”
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Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos by Mitchell, Constance A, Dasgupta, Subham, Zhang, Sharon, Stapleton, Heather M, Volz, David C

“…Abstract Triphenyl phosphate (TPHP) is an unsubstituted aryl phosphate ester used as a flame retardant and plasticizer within the United States. Using…”
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Young children’s exposure to phenols in the home: Associations between house dust, hand wipes, silicone wristbands, and urinary biomarkers by Levasseur, Jessica L., Hammel, Stephanie C., Hoffman, Kate, Phillips, Allison L., Zhang, Sharon, Ye, Xiaoyun, Calafat, Antonia M., Webster, Thomas F., Stapleton, Heather M.

“…•Paired hand wipe, wristband, house dust and urine samples were analyzed for phenols.•Exposure matrices and urinary biomarkers were positively…”
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Young infants’ exposure to organophosphate esters: Breast milk as a potential source of exposure by Hammel, Stephanie C., Zhang, Sharon, Lorenzo, Amelia M., Eichner, Brian, Stapleton, Heather M., Hoffman, Kate

“…[Display omitted] •Biomarkers of organophosphate ester exposure were detected frequently among infants.•TCIPP metabolite levels were significantly higher at 6…”
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Assessing the Effectiveness of Point-of-Use Residential Drinking Water Filters for Perfluoroalkyl Substances (PFASs) by Herkert, Nicholas J, Merrill, John, Peters, Cara, Bollinger, David, Zhang, Sharon, Hoffman, Kate, Ferguson, P. Lee, Knappe, Detlef R. U, Stapleton, Heather M

“…Per- and polyfluoroalkyl substances (PFASs) have come under increased scrutiny due to concerns about their potential toxicity and prevalence in the…”
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Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study by Dicker, Ira, Zhang, Sharon, Ray, Neelanjana, Beno, Brett R, Regueiro-Ren, Alicia, Joshi, Samit, Cockett, Mark, Krystal, Mark, Lataillade, Max

“…GSK3532795 (formerly BMS955176) is a second-generation maturation inhibitor (MI) that progressed through a Phase 2b study for treatment of HIV-1 infection…”
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Marked Hyperbilirubinemia Associated with Primary Myelofibrosis Responsive to Ruxolitinib by Sandhu, Sunny, Chaudhry, Hunza, Zhang, Sharon, Prajapati, Devang

“…Primary myelofibrosis (PMF) is a chronic myeloproliferative disorder seen in older adults which can present both with hepatosplenomegaly as well as mild…”
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PTEN regulation by Akt-EGR1-ARF-PTEN axis by Yu, Jianxiu, Zhang, Sharon S, Saito, Kan, Williams, Scott, Arimura, Yutaka, Ma, Yuliang, Ke, Yuehai, Baron, Veronique, Mercola, Dan, Feng, Gen-Sheng, Adamson, Eileen, Mustelin, Tomas

“…The PTEN tumour suppressor gene is induced by the early growth response 1 (EGR1) transcription factor, which also transactivates p53, p73, and p300/CBP as well…”
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Modulation of Fatty Acid Synthase Degradation by Concerted Action of p38 MAP Kinase, E3 Ligase COP1, and SH2-Tyrosine Phosphatase Shp2 by Yu, Jianxiu, Deng, Rong, Zhu, Helen H., Zhang, Sharon S., Zhu, Changhong, Montminy, Marc, Davis, Roger, Feng, Gen-Sheng

“…The Src-homology 2 (SH2) domain-containing tyrosine phosphatase Shp2 has been known to regulate various signaling pathways triggered by receptor and…”
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Shp2 Controls Female Body Weight and Energy Balance by Integrating Leptin and Estrogen Signals by He, Zhao, Zhang, Sharon S., Meng, Qingyuan, Li, Shuangwei, Zhu, Helen H., Raquil, Marie-Astrid, Alderson, Nazilla, Zhang, Hai, Wu, Jiarui, Rui, Liangyou, Cai, Dongsheng, Feng, Gen-Sheng

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Epigenetic Dysregulation of 5-hydroxymethylcytosine in Well-Differentiated Pancreatic Neuroendocrine Tumors by Sharma, Aarti E., Olivas, Andrea, Parilla, Megan, Yassan, Lindsay, Wang, Hanlin, Zhang, Sharon S., Weber, Christopher, Keutgen, Xavier M., Hart, John, Krausz, Thomas, Setia, Namrata

“…Dysregulation of epigenetic mechanisms, reflected by loss of expression of 5-hydroxymethylcytosine (5-hmC) is being increasingly recognized as a marker of…”
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Diagnostic value of clusterin immunostaining in hepatocellular carcinoma by Li, Yuan, Liu, Fangfang, Zhou, Wendi, Zhang, Sharon, Chu, Peiguo, Lin, Fan, Wang, Hanlin L

“…Background Histologic distinction between well differentiated hepatocellular carcinoma (HCC) and benign hepatocellular mass lesions is a known challenge…”
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How to assess for the full economic value of vaccines? From past to present, drawing lessons for the future by Standaert, Baudouin, Sauboin, Christophe, DeAntonio, Rodrigo, Marijam, Alen, Gomez, Jorge, Varghese, Lijoy, Zhang, Sharon

“…Background:Cost-effectiveness analysis (CEA) is the economic analysis method most commonly applied today in the context of replacing one treatment with a new…”
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Two-Year Assessment of Entecavir Resistance in Lamivudine-Refractory Hepatitis B Virus Patients Reveals Different Clinical Outcomes Depending on the Resistance Substitutions Present by TENNEY, Daniel J, ROSE, Ronald E, EGGERS, Betsy, HSU, Mayla, MARY JANE PLYM, POUNDSTONE, Patricia, YANG, Joanna, COLONNO, Richard J, BALDICK, Carl J, LEVINE, Steven M, POKORNOWSKI, Kevin A, WALSH, Ann W, JIE FANG, YU, Cheng-Fang, SHARON ZHANG, MAZZUCCO, Charles E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic β-cells by Zhang, Sharon S, Hao, Ergeng, Yu, Jianxiu, Liu, Wen, Wang, Jing, Levine, Fred, Feng, Gen-Sheng

“…Intracellular signaling by which pancreatic β-cells synthesize and secrete insulin in control of glucose homeostasis is not fully understood. Here we show that…”
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Total Pancreatectomy with Islet Autotransplantation for the Ampullary Cancer. A Case Report by Savari, Omid, Golab, Karolina, Solomina, Julia, Konsur, Evelyn, Cieply, Kamil, Ramachandran, Sabarinathan, Tekin, Zehra, Schenck, Lindsay, Zhang, Sharon S., Tibudan, Martin, Posner, Mitchell C., Witkowski, Piotr

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Aging and Intermittent Fasting Impact on Transcriptional Regulation and Physiological Responses of Adult Drosophila Neuronal and Muscle Tissues by Zhang, Sharon, Ratliff, Eric P, Molina, Brandon, El-Mecharrafie, Nadja, Mastroianni, Jessica, Kotzebue, Roxanne W, Achal, Madhulika, Mauntz, Ruth E, Gonzalez, Arysa, Barekat, Ayeh, Bray, William A, Macias, Andrew M, Daugherty, Daniel, Harris, Greg L, Edwards, Robert A, Finley, Kim D

“…The progressive decline of the nervous system, including protein aggregate formation, reflects the subtle dysregulation of multiple functional pathways. Our…”
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Deletion of Shp2 Tyrosine Phosphatase in Muscle Leads to Dilated Cardiomyopathy, Insulin Resistance, and Premature Death by Princen, Frederic, Bard, Emilie, Sheikh, Farah, Zhang, Sharon S., Wang, Jing, Zago, Wagner M., Wu, Dongmei, Trelles, Ramon Diaz, Bailly-Maitre, Beatrice, Kahn, C. Ronald, Chen, Yan, Reed, John C., Tong, Gary G., Mercola, Mark, Chen, Ju, Feng, Gen-Sheng

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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