Search Results - "SHANGQIN GUO"

The palette of techniques for cell cycle analysis by Eastman, Anna E., Guo, Shangqin

“…The cell division cycle is the generational period of cellular growth and propagation. Cell cycle progression needs to be highly regulated to preserve genomic…”
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MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors by Chen, Xinyue, Burkhardt, Daniel B., Hartman, Amaleah A., Hu, Xiao, Eastman, Anna E., Sun, Chao, Wang, Xujun, Zhong, Mei, Krishnaswamy, Smita, Guo, Shangqin

“…Cancer is a hyper-proliferative disease. Whether the proliferative state originates from the cell-of-origin or emerges later remains difficult to resolve. By…”
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EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis by Hidalgo, Daniel, Bejder, Jacob, Pop, Ramona, Gellatly, Kyle, Hwang, Yung, Maxwell Scalf, S., Eastman, Anna E., Chen, Jane-Jane, Zhu, Lihua Julie, Heuberger, Jules A. A. C., Guo, Shangqin, Koury, Mark J., Nordsborg, Nikolai Baastrup, Socolovsky, Merav

“…The erythroid terminal differentiation program couples sequential cell divisions with progressive reductions in cell size. The erythropoietin receptor (EpoR)…”
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Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia by Raaijmakers, Marc H. G. P, Scadden, David. T, Mukherjee, Siddhartha, Guo, Shangqin, Zhang, Siyi, Kobayashi, Tatsuya, Schoonmaker, Jesse A, Ebert, Benjamin L, Al-Shahrour, Fatima, Hasserjian, Robert P, Scadden, Edward O, Aung, Zinmar, Matza, Marc, Merkenschlager, Matthias, Lin, Charles, Rommens, Johanna M

“…Mesenchymal cells contribute to the ‘stroma’ of most normal and malignant tissues, with specific mesenchymal cells participating in the regulatory niches of…”
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MKL1-actin pathway restricts chromatin accessibility and prevents mature pluripotency activation by Hu, Xiao, Liu, Zongzhi Z., Chen, Xinyue, Schulz, Vincent P., Kumar, Abhishek, Hartman, Amaleah A., Weinstein, Jason, Johnston, Jessica F., Rodriguez, Elisa C., Eastman, Anna E., Cheng, Jijun, Min, Liz, Zhong, Mei, Carroll, Christopher, Gallagher, Patrick G., Lu, Jun, Schwartz, Martin, King, Megan C., Krause, Diane S., Guo, Shangqin

“…Actin cytoskeleton is well-known for providing structural/mechanical support, but whether and how it regulates chromatin and cell fate reprogramming is far…”
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Activation of FOXO3a by the green tea polyphenol epigallocatechin-3-gallate induces estrogen receptor α expression reversing invasive phenotype of breast cancer cells by BELGUISE, Karine, SHANGQIN GUO, SONENSHEIN, Gail E

“…Previously, we showed that the bioactive green tea polyphenol epigallocatechin-3-gallate (EGCG) inhibits growth in soft agar of breast cancer cells with…”
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MicroRNA miR-125a controls hematopoietic stem cell number by Guo, Shangqin, Lu, Jun, Schlanger, Rita, Zhang, Hao, Wang, Judy Y., Fox, Michelle C., Purton, Louise E., Fleming, Heather H., Cobb, Bradley, Merkenschlager, Matthias, Golub, Todd R., Scadden, David T., Weiss, Mitchell J.

“…MicroRNAs influence hematopoietic differentiation, but little is known about their effects on the stem cell state. Here, we report that the microRNA processing…”
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Nonstochastic Reprogramming from a Privileged Somatic Cell State by Guo, Shangqin, Zi, Xiaoyuan, Schulz, Vincent P., Cheng, Jijun, Zhong, Mei, Koochaki, Sebastian H.J., Megyola, Cynthia M., Pan, Xinghua, Heydari, Kartoosh, Weissman, Sherman M., Gallagher, Patrick G., Krause, Diane S., Fan, Rong, Lu, Jun

“…Reprogramming somatic cells to induced pluripotency by Yamanaka factors is usually slow and inefficient and is thought to be a stochastic process. We…”
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Publisher Correction: MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors by Chen, Xinyue, Burkhardt, Daniel B., Hartman, Amaleah A., Hu, Xiao, Eastman, Anna E., Sun, Chao, Wang, Xujun, Zhong, Mei, Krishnaswamy, Smita, Guo, Shangqin

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Cell circuits between leukemic cells and mesenchymal stem cells block lymphopoiesis by activating lymphotoxin beta receptor signaling by Feng, Xing, Sun, Ruifeng, Lee, Moonyoung, Chen, Xinyue, Guo, Shangqin, Geng, Huimin, Müschen, Marcus, Choi, Jungmin, Pereira, Joao Pedro

“…Acute lymphoblastic and myeloblastic leukemias (ALL and AML) have been known to modify the bone marrow microenvironment and disrupt non-malignant…”
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MicroRNA-Mediated Control of Cell Fate in Megakaryocyte-Erythrocyte Progenitors by Lu, Jun, Guo, Shangqin, Ebert, Benjamin L., Zhang, Hao, Peng, Xiao, Bosco, Jocelyn, Pretz, Jennifer, Schlanger, Rita, Wang, Judy Y., Mak, Raymond H., Dombkowski, David M., Preffer, Frederic I., Scadden, David T., Golub, Todd R.

“…Lineage specification is a critical issue in developmental and regenerative biology. We hypothesized that microRNAs (miRNAs) are important participants in…”
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An Extensive Network of TET2-Targeting MicroRNAs Regulates Malignant Hematopoiesis by Cheng, Jijun, Guo, Shangqin, Chen, Suning, Mastriano, Stephen J., Liu, Chaochun, D’Alessio, Ana C., Hysolli, Eriona, Guo, Yanwen, Yao, Hong, Megyola, Cynthia M., Li, Dan, Liu, Jun, Pan, Wen, Roden, Christine A., Zhou, Xiao-Ling, Heydari, Kartoosh, Chen, Jianjun, Park, In-Hyun, Ding, Ye, Zhang, Yi, Lu, Jun

“…The Ten-Eleven-Translocation 2 (TET2) gene, which oxidates 5-methylcytosine in DNA to 5-hydroxylmethylcytosine (5hmC), is a key tumor suppressor frequently…”
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High-speed automatic characterization of rare events in flow cytometric data by Qi, Yuan, Fang, Youhan, Sinclair, David R, Guo, Shangqin, Alberich-Jorda, Meritxell, Lu, Jun, Tenen, Daniel G, Kharas, Michael G, Pyne, Saumyadipta

“…A new computational framework for FLow cytometric Analysis of Rare Events (FLARE) has been developed specifically for fast and automatic identification of rare…”
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A Molecular Chipper technology for CRISPR sgRNA library generation and functional mapping of noncoding regions by Cheng, Jijun, Roden, Christine A., Pan, Wen, Zhu, Shu, Baccei, Anna, Pan, Xinghua, Jiang, Tingting, Kluger, Yuval, Weissman, Sherman M., Guo, Shangqin, Flavell, Richard A., Ding, Ye, Lu, Jun

“…Clustered regularly-interspaced palindromic repeats (CRISPR)-based genetic screens using single-guide-RNA (sgRNA) libraries have proven powerful to identify…”
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Forkhead Box Transcription Factor FOXO3a Regulates Estrogen Receptor Alpha Expression and Is Repressed by the Her-2/neu/Phosphatidylinositol 3-Kinase/Akt Signaling Pathway by Guo, Shangqin, Sonenshein, Gail E.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Piwi genes are dispensable for normal hematopoiesis in mice by Nolde, Mona J, Cheng, Ee-Chun, Guo, Shangqin, Lin, Haifan

“…Hematopoietic stem cells (HSC) must engage in a life-long balance between self-renewal and differentiation to sustain hematopoiesis. The highly conserved PIWI…”
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Complex oncogene dependence in microRNA-125a–induced myeloproliferative neoplasms by Guo, Shangqin, Bai, Haitao, Megyola, Cynthia M, Halene, Stephanie, Krause, Diane S, Scadden, David T, Lu, Jun

“…Deregulation of microRNA (miRNA) expression can lead to cancer initiation and progression. However, limited information exists on the function of miRNAs in…”
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Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells by PIANETTI, Stefania, SHANGQIN GUO, KAVANAGH, Kathryn T, SONENSHEIN, Gail E

“…Overexpression of the epidermal growth factor receptor family member Her-2/neu in breast cancer is associated with poor prognosis. With evidence accumulating…”
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Green Tea Polyphenols Reverse Cooperation between c-Rel and CK2 that Induces the Aryl Hydrocarbon Receptor, Slug, and an Invasive Phenotype by BELGUISE, Karine, SHANGQIN GUO, SHI YANG, ROGERS, Adrianne E, SELDIN, David C, SHERR, David H, SONENSHEIN, Gail E

“…Exposure to and bioaccumulation of lipophilic environmental pollutants, such as polycyclic aromatic hydrocarbons (PAHs), has been implicated in breast cancer…”
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Incorporating signaling dynamics into fate decision by Guo, Shangqin

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