Search Results - "SHALTIEL, S"

Determination of carbonyl groups in oxidatively modified proteins by reduction with tritiated sodium borohydride by Lenz, A G, Costabel, U, Shaltiel, S, Levine, R L

“…Oxidatively modified proteins have been implicated in a variety of physiologic and pathologic processes. Oxidative modification typically causes inactivation…”
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Vitronectin by Schvartz, Iris, Seger, Dalia, Shaltiel, Shmuel

“…Vitronectin is a multifunctional glycoprotein present in blood and in the extracellular matrix. It binds glycosaminoglycans, collagen, plasminogen and the…”
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Endogenous cleavage of the Arg-379-Ala-380 bond in vitronectin results in a distinct conformational change which buries Ser-378, its site of phosphorylation by protein kinase A by CHAIN, D, KORC-GRODZICKI, B, KREIZMAN, T, SHALTIEL, S

“…Activation of blood platelets by thrombin was previously shown to specifically release protein kinase A, which in human plasma singles out and phosphorylates…”
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Evidence for an extra-cellular function for protein kinase A by Shaltiel, S, Schvartz, I, Korc-Grodzicki, B, Kreizman, T

“…In addition to its intra-cellular functions, cAMP-dependent protein kinase (PKA) may well have an extra-cellular regulatory role in blood. This suggestion is…”
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Platelet Stimulation Releases a cAMP-Dependent Protein Kinase that Specifically Phosphorylates a Plasma Protein by Korc-Grodzicki, Beatriz, Tauber-Finkelstein, Miriam, Shaltiel, Shmuel

“…Rabbit serum is shown to contain a cAMP-dependent protein kinase (biochemically characterized as type II) that specifically phosphorylates a 135-kDa endogenous…”
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Extracellular phosphorylation converts pigment epithelium–derived factor from a neurotrophic to an antiangiogenic factor by Maik-Rachline, Galia, Shaltiel, Shmuel, Seger, Rony

“…The pigment epithelium–derived factor (PEDF) belongs to the superfamily of serine protease inhibitors (serpin). There have been 2 distinct functions attributed…”
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The epidermal growth factor receptor as a substrate for a kinase-splitting membranal proteinase by Seger, R, Yarden, Y, Kashles, O, Goldblatt, D, Schlessinger, J, Shaltiel, S

“…A brush-border membranal proteinase, which specifically clips the catalytic subunit of cAMP-dependent protein kinase, is shown to cleave the receptor for the…”
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Studying the structure of the intracellular moiety of the insulin receptor with a kinase‐splitting membranal proteinase by Seger, R., Zick, Y., Shaltiel, S.

“…A kinase‐splitting membranal proteinase specifically clips the cytoplasmic moiety of the insulin receptor beta‐subunit (95 kd) to yield an 84‐kd fragment…”
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Affinity Labeling of the Catalytic Subunit of Cyclic AMP-Dependent Protein Kinase by Nα-tosyl-L-lysine Chloromethyl Ketone by Kupfer, A., Gani, V., Jiménez, J. S., Shaltiel, S.

“…The catalytic subunit of cyclic AMP-dependent protein kinase (from rabbit skeletal muscle; ATP:protein phosphotransferase, EC 2.7.1.37) was found to be…”
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A Selective Interaction between OS-9 and the Carboxyl-terminal Tail of Meprin β by Litovchick, Larisa, Friedmann, Elena, Shaltiel, Shmuel

“…OS-9, a protein previously uncharacterized, was shown to interact specifically with the intracellular region of the membrane proteinase meprin β found in brush…”
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Hydrophobic Chromatography: Use for Purification of Glycogen Synthetase by Shaltiel, Shmuel, Er-El, Zvi

“…A homologous series of ω -aminoalkyl-agaroses [Sepharose-NH(CH2)nNH2] that varied in the length of their hydrocarbon side chains was synthesized. This family…”
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Degradative Inactivation of Cyclic AMP-Dependent Protein Kinase by a Membranal Proteinase is Restricted to the Free Catalytic Subunit in Its Native Conformation by Alhanaty, Eytan, Patinkin, Jonathan, Tauber-Finkelstein, Miriam, Shaltiel, Shmuel

“…A membranal proteinase from brush-border epithelial cells of the rat small intestine was shown to bring about a restricted and limited degradation of the free…”
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Hydrophobic chromatography of cells: adsorption and resolution on homologous series of alkylagaroses by Halperin, G, Tauber-Finkelstein, M, Shaltiel, S

“…Implantation of hydrocarbon chains on beaded agarose results in column materials capable of adsorbing erythrocytes or lymphocytes from various sources. In a…”
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A periodicity in the response of SJL/J thymocytes to isoproterenol. Simulation by cell lines by Riven-Kreitman, R, Tauber-Finkelstein, M, Zipori, D, Shaltiel, S

“…Thymocytes from SJL/J mice exhibit a periodicity in their response to hormonal stimulation with isoproterenol. This periodicity (5-9 days) is expressed in…”
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Exposure of thymocytes to a low temperature (4 degrees C) inhibits the onset of their hormone-induced cellular refractoriness by Zick, Y, Cesla, R, Shaltiel, S

“…The hormonal response of viable mouse thymocytes is radically dependent of their ambient temperature. While at 37 degrees C the cells respond to isoproterenol…”
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Snapping of the Carboxyl Terminal Tail of the Catalytic Subunit of PKA onto Its Core:  Characterization of the Sites by Mutagenesis by Batkin, Michael, Schvartz, Iris, Shaltiel, Shmuel

“…A set of 45 mutants of the carboxyl terminal tail of the PKA catalytic subunit was prepared and used to assess the contribution of this tail to the structure…”
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cAMP-dependent protein kinase from mouse thymocytes. Localization, characterization, and evaluation of the physiological relevance of a massive cytosol to nucleus translocation by Zick, Y, Cesla, R, Shaltiel, S

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YOS9, the Putative Yeast Homolog of a Gene Amplified in Osteosarcomas, Is Involved in the Endoplasmic Reticulum (ER)-Golgi Transport of GPI-anchored Proteins by Friedmann, Elena, Salzberg, Yehuda, Weinberger, Adina, Shaltiel, Shmuel, Gerst, Jeffrey E

“…The OS-9 gene maps to a region (q13–15) of chromosome 12 that is highly amplified in human osteosarcomas and encodes a protein of unknown function. Here we…”
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Phosphorylation of vitronectin by casein kinase II. Identification of the sites and their promotion of cell adhesion and spreading by Seger, D, Gechtman, Z, Shaltiel, S

“…The cell adhesion protein vitronectin (Vn) was previously shown to be the major target in human blood for an extracellular protein kinase A, which is released…”
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Distinct conformational changes in the catalytic subunit of cAMP-dependent protein kinase around physiological conditions. Do these changes reflect an ability to assume different specificities? by Kupfer, A, Jiménez, J S, Shaltiel, S

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