Search Results - "SHALHOUB, Victoria"
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FGF23 regulates renal sodium handling and blood pressure
Published in EMBO molecular medicine (01-06-2014)“…Fibroblast growth factor‐23 (FGF23) is a bone‐derived hormone regulating renal phosphate reabsorption and vitamin D synthesis in renal proximal tubules. Here,…”
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Performance evaluation of four 25-hydroxyvitamin D assays to measure 25-hydroxyvitamin D2
Published in Clinical biochemistry (01-11-2015)“…The ability of current immunoassays to accurately measure equimolar amounts of 25(OH)D2 and 25(OH)D3 has been recently questioned. This study determined serum…”
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Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis
Published in Journal of bone and mineral research (01-04-2009)“…The development of bone‐rebuilding anabolic agents for potential use in the treatment of bone loss conditions, such as osteoporosis, has been a long‐standing…”
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FGF23 Fails to Inhibit Uremic Parathyroid Glands
Published in Journal of the American Society of Nephrology (01-07-2010)“…Fibroblast growth factor 23 (FGF23) modulates mineral metabolism by promoting phosphaturia and decreasing the production of 1,25-dihydroxyvitamin D(3). FGF23…”
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The calcimimetic AMG 641 abrogates parathyroid hyperplasia, bone and vascular calcification abnormalities in uremic rats
Published in European journal of pharmacology (15-08-2009)“…Calcimimetics and vitamin D sterols reduce serum parathyroid hormone (PTH) in patients with secondary hyperparathyroidism receiving dialysis, a disease state…”
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Osteoprotegerin: a physiological and pharmacological inhibitor of bone resorption
Published in Current pharmaceutical design (01-05-2001)“…OPG is a new member of the tumor necrosis factor (TNF) receptor family which plays a key role in the physiological regulation of osteoclastic bone resorption…”
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Influence of Vitamin D Binding Protein on Accuracy of 25-Hydroxyvitamin D Measurement Using the ADVIA Centaur Vitamin D Total Assay
Published in International Journal of Endocrinology (01-01-2014)“…Vitamin D status in different populations relies on accurate measurement of total serum 25-hydroxyvitamin D [25(OH)D] concentrations [i.e., 25(OH)D3 and…”
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Erratum to “Influence of Vitamin D Binding Protein on Accuracy of 25-Hydroxyvitamin D Measurement Using the ADVIA Centaur Vitamin D Total Assay”
Published in International journal of endocrinology (2014)“…The graphs in Figure 4(b) appear as duplicates of graphs in Figure 4(a) and are corrected as follows…”
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Infrequent Delivery of a Long‐Acting PTH‐Fc Fusion Protein Has Potent Anabolic Effects on Cortical and Cancellous Bone
Published in Journal of bone and mineral research (01-10-2007)“…Skeletal anabolism with PTH is achieved through daily injections that result in brief exposure to the peptide. We hypothesized that similar anabolic effects…”
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FGF23 promotes renal calcium reabsorption through the TRPV5 channel
Published in The EMBO journal (03-02-2014)Get full text
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Analytical performance of the Enhanced Liver Fibrosis (ELF) Test on the Atellica IM Analyzer
Published in Clinica chimica acta (01-08-2023)“…•ELFTM aids prognostic evaluation in patients with advanced liver fibrosis in NASH.•The ELF score comprises results of 3 fibrosis markers, HA, PIIINP, and…”
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Osteoclast markers accumulate on cells developing from human peripheral blood mononuclear precursors
Published in Journal of cellular biochemistry (01-01-1999)“…Recent studies show that human osteoclasts develop in vitro from hematopoietic cells; however, special cultures conditions and/or cytokine mobilized peripheral…”
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Glucocorticoids promote development of the osteoblast phenotype by selectively modulating expression of cell growth and differentiation associated genes
Published in Journal of cellular biochemistry (01-12-1992)“…To understand the mechanisms by which glucocorticoids promote differentiation of fetal rat calvaria derived osteoblasts to produce bone-like mineralized…”
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FGF23 promotes renal calcium reabsorption through the TRPV5 channel
Published in The EMBO journal (03-02-2014)“…αKlotho is thought to activate the epithelial calcium channel Transient Receptor Potential Vanilloid‐5 (TRPV5) in distal renal tubules through its putative…”
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FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality
Published in The Journal of clinical investigation (01-07-2012)“…Chronic kidney disease-mineral and bone disorder (CKD-MBD) is associated with secondary hyperparathyroidism (HPT) and serum elevations in the phosphaturic…”
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Multiple levels of steroid hormone-dependent control of osteocalcin during osteoblast differentiation: Glucocorticoid regulation of basal and vitamin D stimulated gene expression
Published in Journal of cellular biochemistry (01-05-1998)“…We have examined the contribution of transcriptional mechanisms to the pleiotropic effects of glucocorticoids on basal and vitamin D stimulated expression of…”
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Analytical characterization of the SARS-CoV-2 EURM-017 reference material
Published in Clinical biochemistry (01-03-2022)“…•EURM-017 is human serum reference material for anti-SARS-CoV-2 serology assays.•Antibody fractions (S1 RBD, N, S1, S2, and full-length S) were affinity…”
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FGF23 neutralization improves bone quality and osseointegration of titanium implants in chronic kidney disease mice
Published in Scientific reports (10-02-2015)“…Chronic kidney disease (CKD) is a worldwide health problem. Serum levels of FGF23, a phosphaturic hormone, increase at the earliest stages of CKD and have been…”
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Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia
Published in Bone (New York, N.Y.) (01-10-2006)“…Mutations affecting the activity of the Wnt co-receptors LRP5 and LRP6 that cause alterations in skeletal biology confirmed the involvement of Wnt signaling in…”
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