Search Results - "SHAHAM, Yavin"

An operant social self-administration and choice model in rats by Venniro, Marco, Shaham, Yavin

“…It is difficult to translate results from animal research on addiction to an understanding of the behavior of human drug users. Despite decades of basic…”
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Improving translation of animal models of addiction and relapse by reverse translation by Venniro, Marco, Banks, Matthew L., Heilig, Markus, Epstein, David H., Shaham, Yavin

“…Critical features of human addiction are increasingly being incorporated into complementary animal models, including escalation of drug intake, punished drug…”
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Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability by Bonaventura, Jordi, Lam, Sherry, Carlton, Meghan, Boehm, Matthew A., Gomez, Juan L., Solís, Oscar, Sánchez-Soto, Marta, Morris, Patrick J., Fredriksson, Ida, Thomas, Craig J., Sibley, David R., Shaham, Yavin, Zarate, Carlos A., Michaelides, Michael

“…Ketamine, a racemic mixture of (S)-ketamine and (R)-ketamine enantiomers, has been used as an anesthetic, analgesic and more recently, as an antidepressant…”
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Animal Models of (or for) Aggression Reward, Addiction, and Relapse: Behavior and Circuits by Golden, Sam A, Jin, Michelle, Shaham, Yavin

“…Inappropriate and pathological aggression plays a leading role in the suffering and death of millions of people, and further places an untenable strain on the…”
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Circuit and Synaptic Plasticity Mechanisms of Drug Relapse by Dong, Yan, Taylor, Jane R, Wolf, Marina E, Shaham, Yavin

“…High rates of relapse to drug use during abstinence is a defining feature of human drug addiction. This clinical scenario has been studied at the preclinical…”
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Recent findings on the role of sensory and interoceptive-related circuits in relapse to drug seeking by Reiner, David J, Shaham, Yavin

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The protective effect of operant social reward on cocaine self-administration, choice, and relapse is dependent on delay and effort for the social reward by Venniro, Marco, Panlilio, Leigh V, Epstein, David H, Shaham, Yavin

“…Social reinforcement-based treatments are effective for many, but not all, people with addictions to drugs. We recently developed an operant rat model that…”
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Volitional social interaction prevents drug addiction in rat models by Venniro, Marco, Zhang, Michelle, Caprioli, Daniele, Hoots, Jennifer K., Golden, Sam A., Heins, Conor, Morales, Marisela, Epstein, David H., Shaham, Yavin

“…Addiction treatment has not been appreciably improved by neuroscientific research. One problem is that mechanistic studies using rodent models do not…”
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Neurobiology of the incubation of drug craving by Pickens, Charles L, Airavaara, Mikko, Theberge, Florence, Fanous, Sanya, Hope, Bruce T, Shaham, Yavin

“…It was suggested in 1986 that cue-induced drug craving in cocaine addicts progressively increases over the first several weeks of abstinence and remains high…”
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Opiate versus psychostimulant addiction: the differences do matter by Badiani, Aldo, Shaham, Yavin, Belin, David, Epstein, David, Calu, Donna

“…Current theories of addiction all argue for a unitary account of drug addiction. Badiani and colleagues challenge this view by highlighting behavioural,…”
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Context-induced relapse to drug seeking: a review by Crombag, Hans S, Bossert, Jennifer M, Koya, Eisuke, Shaham, Yavin

“…In humans, exposure to environmental contexts previously associated with drug intake often provokes relapse to drug use, but the mechanisms mediating this…”
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Aggression Addiction and Relapse: A New Frontier in Psychiatry by Golden, Sam A, Shaham, Yavin

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The impact of orbitofrontal dysfunction on cocaine addiction by Lucantonio, Federica, Stalnaker, Thomas A, Shaham, Yavin, Niv, Yael, Schoenbaum, Geoffrey

“…Here the authors review evidence suggesting that cocaine-induced changes in orbitofrontal cortex disrupt the representation of states and transition functions…”
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Effect of the dopamine stabilizer (-)-OSU6162 on potentiated incubation of opioid craving after electric barrier-induced voluntary abstinence by Fredriksson, Ida, Applebey, Sarah V, Minier-Toribio, Angelica, Shekara, Aniruddha, Bossert, Jennifer M, Shaham, Yavin

“…In the classical incubation of drug craving rat model, drug seeking is assessed after homecage forced abstinence. However, human abstinence is often voluntary…”
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Compulsive addiction-like aggressive behavior in mice by Golden, Sam A, Heins, Conor, Venniro, Marco, Caprioli, Daniele, Zhang, Michelle, Epstein, David, Shaham, Yavin

“…Abstract Background Some people are highly motivated to seek aggressive encounters, and among those who have been incarcerated for such behavior, recidivism…”
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New technologies for examining the role of neuronal ensembles in drug addiction and fear by Cruz, Fabio C., Koya, Eisuke, Guez-Barber, Danielle H., Bossert, Jennifer M., Lupica, Carl R., Shaham, Yavin, Hope, Bruce T.

“…The idea that learned associations are encoded within neuronal ensembles has so far mainly been based on correlational data. This Progress article describes…”
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Running is the neurogenic and neurotrophic stimulus in environmental enrichment by Kobilo, Tali, Liu, Qing-Rong, Gandhi, Kriti, Mughal, Mohammed, Shaham, Yavin, van Praag, Henriette

“…Environmental enrichment (EE) increases dentate gyrus (DG) neurogenesis and brain-derived neurotrophic factor (BDNF) levels. However, running is considered an…”
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Effect of the Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 2 AZD8529 on Incubation of Methamphetamine Craving After Prolonged Voluntary Abstinence in a Rat Model by Caprioli, Daniele, Venniro, Marco, Zeric, Tamara, Li, Xuan, Adhikary, Sweta, Madangopal, Rajtarun, Marchant, Nathan J, Lucantonio, Federica, Schoenbaum, Geoffrey, Bossert, Jennifer M, Shaham, Yavin

“…Abstract Background Cue-induced methamphetamine craving increases after prolonged forced (experimenter-imposed) abstinence from the drug (incubation of…”
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A Memory Retrieval-Extinction Procedure to Prevent Drug Craving and Relapse by Xue, Yan-Xue, Luo, Yi-Xiao, Wu, Ping, Shi, Hai-Shui, Xue, Li-Fen, Chen, Chen, Zhu, Wei-Li, Ding, Zeng-Bo, Bao, Yan-ping, Shi, Jie, Epstein, David H., Shaham, Yavin, Lu, Lin

“…Drug use and relapse involve learned associations between drug-associated environmental cues and drug effects. Extinction procedures in the clinic can suppress…”
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Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving by Tseng, Kuei Y, Reimers, Jeremy M, Uejima, Jamie L, Conrad, Kelly L, Marinelli, Michela, Wolf, Marina E, Shaham, Yavin, Heng, Li-Jun

“…Relapse to cocaine use after prolonged abstinence is an important clinical problem. This relapse is often induced by exposure to cues associated with cocaine…”
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