Search Results - "SHAH, R R"
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Safety and Tolerability of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors in Oncology
Published in Drug safety (01-02-2019)“…Tyrosine kinase inhibitors (TKIs) that target epidermal growth factor receptor (EGFR) have dramatically improved progression-free survival in non-small-cell…”
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2
Safety and Tolerability of Histone Deacetylase (HDAC) Inhibitors in Oncology
Published in Drug safety (01-02-2019)“…Histone deacetylases (HDACs) are expressed at increased levels in cells of various malignancies, and the use of HDAC inhibitors has improved outcomes in…”
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3
Hepatotoxicity of Tyrosine Kinase Inhibitors: Clinical and Regulatory Perspectives
Published in Drug safety (01-07-2013)“…The introduction of small-molecule tyrosine kinase inhibitors (TKIs) in clinical oncology has transformed the treatment of certain forms of cancers. As of 31…”
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4
Measuring adiposity in patients: the utility of body mass index (BMI), percent body fat, and leptin
Published in PloS one (02-04-2012)“…Obesity is a serious disease that is associated with an increased risk of diabetes, hypertension, heart disease, stroke, and cancer, among other diseases. The…”
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Tyrosine Kinase Inhibitor-Induced Interstitial Lung Disease: Clinical Features, Diagnostic Challenges, and Therapeutic Dilemmas
Published in Drug safety (01-11-2016)“…Since the approval of the first molecularly targeted tyrosine kinase inhibitor (TKI), imatinib, in 2001, TKIs have heralded a new era in the treatment of many…”
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6
Chiral Magnetism and High-Temperature Skyrmions in B20-Ordered Co-Si
Published in Physical review letters (07-02-2020)“…Magnets with chiral crystal structures and helical spin structures have recently attracted much attention as potential spin-electronics materials, but their…”
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7
Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice
Published in Proceedings of the National Academy of Sciences - PNAS (17-06-2014)“…The mammalian heart has long been considered a postmitotic organ, implying that the total number of cardiomyocytes is set at birth. Analysis of cell division…”
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8
Prevalent diabetes and long-term cardiovascular outcomes in adult sepsis survivors: a population-based cohort study
Published in Critical care (London, England) (31-07-2023)“…Sepsis survivors are at elevated risk for cardiovascular disease during long-term follow-up. Whether diabetes influences cardiovascular risk after sepsis…”
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Cardiovascular Safety of Tyrosine Kinase Inhibitors: With a Special Focus on Cardiac Repolarisation (QT Interval)
Published in Drug safety (01-05-2013)“…The development of tyrosine kinase inhibitors (TKI) represents a major milestone in oncology. However, their use has been found to be associated with serious…”
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10
66-OR: The Lasting Effects of Redlining on Diabetes Rates—A Tri-city Statistical Analysis
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Introduction: The relationship between redlining and diabetes prevalence has been understudied. Residents of redlined tracts experience risk factors…”
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Tyrosine Kinase Inhibitors: Their On-Target Toxicities as Potential Indicators of Efficacy
Published in Drug safety (01-06-2013)“…Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of certain forms of cancers, raising hopes for many patients with otherwise unresponsive…”
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12
Anomalous Aortic Origin of a Coronary Artery From the Inappropriate Sinus of Valsalva
Published in Journal of the American College of Cardiology (28-03-2017)“…Abstract Anomalous aortic origin of a coronary artery (AAOCA) from the inappropriate sinus of Valsalva is increasingly recognized by cardiac imaging. Although…”
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13
Two Higgs doublets and a complex singlet: disentangling the decay topologies and associated phenomenology
Published in The journal of high energy physics (01-12-2018)“…A bstract We present a systematic study of an extension of the Standard Model (SM) with two Higgs doublets and one complex singlet (2HDM+S). In order to gain…”
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14
Astaxanthin-Producing Green Microalga Haematococcus pluvialis: From Single Cell to High Value Commercial Products
Published in Frontiers in plant science (28-04-2016)“…Many species of microalgae have been used as source of nutrient rich food, feed, and health promoting compounds. Among the commercially important microalgae,…”
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15
Mediating effect of vascular risk factors underlying the link between gestational diabetes and cardiovascular disease
Published in BMC medicine (04-11-2022)“…Background Women with gestational diabetes (GDM) have an elevated lifetime incidence of cardiovascular disease (CVD), but the basis of this excess risk remains…”
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Total daily physical activity and the risk of AD and cognitive decline in older adults
Published in Neurology (24-04-2012)“…Studies examining the link between objective measures of total daily physical activity and incident Alzheimer disease (AD) are lacking. We tested the…”
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17
Impersonating the Standard Model Higgs boson: alignment without decoupling
Published in The journal of high energy physics (01-04-2014)“…A bstract In models with an extended Higgs sector there exists an alignment limit, in which the lightest CP-even Higgs boson mimics the Standard Model Higgs…”
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The tiny (g-2) muon wobble from small-μ supersymmetry
Published in The journal of high energy physics (01-01-2022)“…A bstract A new measurement of the muon anomalous magnetic moment, g μ − 2, has been reported by the Fermilab Muon g-2 collaboration and shows a 4 . 2 σ…”
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Pathophysiology, phenotypes and management of type 2 diabetes mellitus in Indian and Chinese populations
Published in Nature reviews. Endocrinology (01-07-2022)“…Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These populations have an underlying predisposition to deficient…”
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3D-printing porosity: A new approach to creating elevated porosity materials and structures
Published in Acta biomaterialia (01-05-2018)“…[Display omitted] We introduce a new process that enables the ability to 3D-print high porosity materials and structures by combining the newly introduced…”
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