Search Results - "SEWELL, Jane M"

Neuregulin Expression, Function, and Signaling in Human Ovarian Cancer Cells by GILMOUR, Lynn M. R, MACLEOD, Kenneth G, MCCAIG, Alison, SEWELL, Jane M, GULLICK, William J, SMYTH, John F, LANGDON, Simon P

“…Purpose: To investigate the expression and function of neuregulin (NRG) isoforms in ovarian cancer cell lines and tumor samples. Experimental Design:…”
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Raf-1 is the predominant Raf isoform that mediates growth factor-stimulated growth in ovarian cancer cells by McPhillips, Fiona, Mullen, Peter, MacLeod, Kenneth G., Sewell, Jane M., Monia, Brett P., Cameron, David A., Smyth, John F., Langdon, Simon P.

“…There is currently much interest in the role of the Raf family in cancer, particularly since mutated B-Raf has been shown to be oncogenic in certain disease…”
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Role of TGFα stimulation of the ERK, PI3 kinase and PLCγ pathways in ovarian cancer growth and migration by Sewell, Jane M., Smyth, John F., Langdon, Simon P.

“…The Epidermal Growth Factor Receptor (EGFR) and its structural relative erbB2 are frequently over-expressed in ovarian cancers and both are strongly associated…”
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