Search Results - "SEWALT, Richard G. A. B"
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The polycomb group protein EZH2 is involved in progression of prostate cancer
Published in Nature (London) (10-10-2002)“…Prostate cancer is a leading cause of cancer-related death in males and is second only to lung cancer. Although effective surgical and radiation treatments…”
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EZH2 Is a Marker of Aggressive Breast Cancer and Promotes Neoplastic Transformation of Breast Epithelial Cells
Published in Proceedings of the National Academy of Sciences - PNAS (30-09-2003)“…The Polycomb Group Protein EZH2 is a transcriptional repressor involved in controlling cellular memory and has been linked to aggressive prostate cancer. Here…”
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Selective Interactions between Vertebrate Polycomb Homologs and the SUV39H1 Histone Lysine Methyltransferase Suggest that Histone H3-K9 Methylation Contributes to Chromosomal Targeting of Polycomb Group Proteins
Published in Molecular and Cellular Biology (01-08-2002)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Unique Polycomb Gene Expression Pattern in Hodgkin's Lymphoma and Hodgkin's Lymphoma-Derived Cell Lines
Published in The American journal of pathology (01-03-2004)“…Human Polycomb-group (PcG) genes play a crucial role in the regulation of embryonic development and regulation of the cell cycle and hematopoiesis. PcG genes…”
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Identification of anti-repressor elements that confer high and stable protein production in mammalian cells
Published in Nature biotechnology (01-05-2003)“…The expression of transgenic proteins is often low and unstable over time, a problem that may be due to integration of the transgene in repressed chromatin. We…”
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Characterization of Interactions between the Mammalian Polycomb-Group Proteins Enx1/EZH2 and EED Suggests the Existence of Different Mammalian Polycomb-Group Protein Complexes
Published in Molecular and Cellular Biology (01-06-1998)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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C-Terminal Binding Protein Is a Transcriptional Repressor That Interacts with a Specific Class of Vertebrate Polycomb Proteins
Published in Molecular and Cellular Biology (01-01-1999)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Distinct expression patterns of polycomb oncoproteins and their binding partners during the germinal center reaction
Published in European Journal of Immunology (01-07-2004)“…Polycomb group (PcG) genes encode two chromatin‐binding protein complexes, the PRC1 and the PRC2 PcG complexes, which are essential for the maintenance of cell…”
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Various Expression-Augmenting DNA Elements Benefit from STAR-Select, a Novel High Stringency Selection System for Protein Expression
Published in Biotechnology progress (01-07-2007)“…The creation of highly productive mammalian cell lines often requires the screening of large numbers of clones, and even then expression levels are often low…”
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Site-Specific Expression of Polycomb-Group Genes Encoding the HPC-HPH/PRC1 Complex in Clinically Defined Primary Nodal and Cutaneous Large B-Cell Lymphomas
Published in The American journal of pathology (01-02-2004)“…Polycomb-group (PcG) genes preserve cell identity by gene silencing, and contribute to regulation of lymphopoiesis and malignant transformation. We show that…”
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A bipartite sequence element associated with matrix/ scaffold attachment regions
Published in Nucleic acids research (15-07-1999)“…We have identified a MAR/SAR recognition signature (MRS) which is common to a large group of matrix and scaffold attachment regions. The MRS is composed of two…”
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Increased Expression of the EZH2 Polycomb Group Gene in BMI-1-Positive Neoplastic Cells during Bronchial Carcinogenesis
Published in Neoplasia (New York, N.Y.) (01-11-2004)“…Polycomb group (PcG) genes are responsible for maintenance of cellular identity and contribute to regulation of the cell cycle. Recent studies have identified…”
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A panel of monoclonal antibodies against human polycomb group proteins
Published in Hybridoma and hybridomics (01-08-2002)“…Polycomb-group (PcG) proteins are chromatin-associated proteins that heritably repress gene activity in many organisms, including man. Two distinct human PcG…”
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Transcriptional Repression Mediated by Polycomb Group Proteins and Other Chromatin-associated Repressors Is Selectively Blocked by Insulators
Published in The Journal of biological chemistry (07-01-2000)“…Polycomb group (PcG) proteins repress gene activity over a considerable distance, possibly by spreading along the chromatin fiber. Insulators or boundary…”
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Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis
Published in Molecular and Cellular Biology (01-10-1997)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Increased Expression of the EZH2 Polycomb Group Gene in BMI-1-Positive Neoplastic Cells during Bronchial Carcinogenesis1
Published in Neoplasia (New York, N.Y.) (01-11-2004)“…Polycomb group (PcG) genes are responsible for maintenance of cellular identity and contribute to regulation of the cell cycle. Recent studies have identified…”
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