Search Results - "SETTERBLAD, Niclas"
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Self-organization and culture of Mesenchymal Stem Cell spheroids in acoustic levitation
Published in Scientific reports (16-04-2021)“…In recent years, 3D cell culture models such as spheroid or organoid technologies have known important developments. Many studies have shown that 3D cultures…”
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Journal Article -
2
An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation
Published in Developmental cell (10-04-2017)“…Global transcriptome reprogramming during spermatogenesis ensures timely expression of factors in each phase of male germ cell differentiation. Spermatocytes…”
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Journal Article -
3
Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins
Published in The Journal of cell biology (17-03-2014)“…The promyelocytic leukemia (PML) protein organizes PML nuclear bodies (NBs), which are stress-responsive domains where many partner proteins accumulate. Here,…”
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4
Author Correction: Self‑organization and culture of Mesenchymal Stem Cell spheroids in acoustic levitation
Published in Scientific reports (15-06-2021)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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5
Stem cells increase in numbers in perinecrotic areas in human renal cancer
Published in Clinical cancer research (15-02-2015)“…Developing strategies to overcome resistance to sunitinib is a major challenge in human renal cell carcinoma (RCC). We hypothesized that sunitinib-induced…”
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6
Development and qualification of clinical grade decellularized and cryopreserved human esophagi
Published in Scientific reports (25-10-2023)“…Tissue engineering is a promising alternative to current full thickness circumferential esophageal replacement methods. The aim of our study was to develop a…”
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Journal Article -
7
CD4 + CD8 + T-Lymphocytes in Xenogeneic and Human Graft-versus-Host Disease
Published in Frontiers in immunology (24-11-2020)“…Mechanisms driving acute graft-versus-host disease (aGVHD) onset in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) are…”
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8
BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome
Published in International journal of molecular sciences (30-09-2021)“…During transformation, myelodysplastic syndromes (MDS) are characterized by reducing apoptosis of bone marrow (BM) precursors. Mouse models of high risk…”
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Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome
Published in Blood (06-01-2011)“…The human T-lymphotropic virus type I oncoprotein Tax is critical for T-cell transformation, acting mainly through nuclear factor kappa B essential modulator…”
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10
Dynamics of Thymus-Colonizing Cells during Human Development
Published in Immunity (Cambridge, Mass.) (01-02-2006)“…Here, we identify fetal bone marrow (BM)-derived CD34 hiCD45RA hiCD7 + hematopoietic progenitors as thymus-colonizing cells. This population, virtually absent…”
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Journal Article -
11
EMMPRIN regulates β1 integrin-mediated adhesion through Kindlin-3 in human melanoma cells
Published in Experimental dermatology (01-06-2015)“…EMMPRIN is known to promote tumor invasion through extracellular matrix (ECM) degradation. Here we report that EMMPRIN can regulate melanoma cell adhesion to…”
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12
MHC class II/CD38/CD9: a lipid-raft–dependent signaling complex in human monocytes
Published in Blood (01-11-2005)“…Despite a lack of signaling motifs in their cytoplasmic domain, major histocompatibility complex (MHC) class II molecules trigger a variety of intracellular…”
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13
Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome
Published in Retrovirology (06-06-2011)“…n.a…”
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Journal Article Conference Proceeding -
14
MHC class II signaling function is regulated during maturation of plasmacytoid dendritic cells
Published in Journal of leukocyte biology (01-04-2005)“…Dendritic cells (DC) play a central role in the immune response, linking innate and adaptative responses to pathogens. Myeloid DC (MDC) produce interleukin‐12…”
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15
Composition of MHC class II-enriched lipid microdomains is modified during maturation of primary dendritic cells
Published in Journal of leukocyte biology (01-07-2003)“…Dendritic cells (DCs) are the most potent antigen presenting cells. Major histocompatibility complex (MHC) class II molecule expression changes with…”
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16
MHC class II‐mediated apoptosis of mature dendritic cells proceeds by activation of the protein kinase C‐δ isoenzyme
Published in International immunology (01-08-2002)“…The mature dendritic cell (DC) is considered to be the most potent antigen‐presenting cell. Regulation of the DC, particularly its survival, is therefore…”
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17
Cognate MHC–TCR interaction leads to apoptosis of antigen-presenting cells
Published in Journal of leukocyte biology (01-06-2004)“…Antigen presentation to T lymphocytes has been characterized extensively in terms of T lymphocyte activation and eventual cell death. In contrast, little is…”
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18
Osteogenic-differentiated mesenchymal stem cell-secreted extracellular matrix as a bone morphogenetic protein-2 delivery system for ectopic bone formation
Published in Acta biomaterialia (15-10-2020)“…While human bone morphogenetic protein-2 (BMP-2) is a promising growth factor for bone regeneration, a major challenge in biomedical applications is finding an…”
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Journal Article -
19
Self-organization and culture of Mesenchymal Stromal Cell spheroids in acoustic levitation
Published in Scientific reports (16-04-2021)“…In recent years, 3D cell culture models such as spheroid or organoid technologies have known important developments. Many studies have shown that 3D cultures…”
Get full text
Journal Article -
20
Acute myeloid leukemia impairs natural killer cells through the formation of a deficient cytotoxic immunological synapse
Published in European journal of immunology (01-10-2014)“…Acute myeloid leukemia (AML) cells are killed by allogeneic NK cells. However, autologous NK cells from AML patients express decreased levels of activating…”
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