Search Results - "SETOGUCHI, Takao"

Persistence of a Small Subpopulation of Cancer Stem-like Cells in the C6 Glioma Cell Line by Kondo, Toru, Setoguchi, Takao, Taga, Tetsuya

“…Both stem cells and cancer cells are thought to be capable of unlimited proliferation. Paradoxically, however, some cancers seem to contain stem-like cells…”
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Risk Factors for Surgical Site Infection after Soft-Tissue Sarcoma Resection, Including the Preoperative Geriatric Nutritional Risk Index by Sasaki, Hiromi, Nagano, Satoshi, Taniguchi, Noboru, Setoguchi, Takao

“…Malignant soft-tissue sarcoma resection is associated with a relatively high incidence of surgical site infection (SSI). The known risk factors for SSI…”
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Low geriatric nutritional risk index is a risk factor for death within 1 year following hip fracture by Fujimoto, Yusuke, Setoguchi, Takao, Ishidou, Yasuhiro, Taniguchi, Noboru

“…Purpose Hip fracture is common in older patients and is associated with high mortality and functional impairment. The Geriatric Nutritional Risk Index (GNRI)…”
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Risk factors for surgical site infection and urinary tract infection after spine surgery by Tominaga, Hiroyuki, Setoguchi, Takao, Ishidou, Yasuhiro, Nagano, Satoshi, Yamamoto, Takuya, Komiya, Setsuro

“…Purpose This study aimed to identify and compare risk factors for surgical site infection (SSI) and non-surgical site infections (non-SSIs), particularly…”
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Synergistic effect of arsenic trioxide, vismodegib and temozolomide on glioblastoma by Bureta, Costansia, Saitoh, Yoshinobu, Tokumoto, Hiroto, Sasaki, Hiromi, Maeda, Shingo, Nagano, Satoshi, Komiya, Setsuro, Taniguchi, Noboru, Setoguchi, Takao

“…The treatment of glioblastoma is a critical health issue, owing to its resistance to chemotherapy. The current standard of treatment is surgical resection,…”
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Validation of Different Nutritional Assessment Tools in Predicting Prognosis of Patients with Soft Tissue Spindle-Cell Sarcomas by Sasaki, Hiromi, Nagano, Satoshi, Komiya, Setsuro, Taniguchi, Noboru, Setoguchi, Takao

“…Predicting outcomes in patients with soft tissue sarcoma (STS) is challenging. To improve these predictions, we retrospectively analyzed common nutritional…”
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Differentiation of lipoma and atypical lipomatous tumor by a scoring system: implication of increased vascularity on pathogenesis of liposarcoma by Nagano, Satoshi, Yokouchi, Masahiro, Setoguchi, Takao, Ishidou, Yasuhiro, Sasaki, Hiromi, Shimada, Hirofumi, Komiya, Setsuro

“…Well-differentiated liposarcoma (WDL)/atypical lipomatous tumor (ALT) is considered a low-grade malignancy that rarely metastasizes but should be carefully…”
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Current therapeutic modalities and newly designed gene therapy for refractory sarcomas by Komiya, Setsuro, Nagano, Satoshi, Setoguchi, Takao

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Smoothened as a new therapeutic target for human osteosarcoma by Hirotsu, Masataka, Setoguchi, Takao, Sasaki, Hiromi, Matsunoshita, Yukihiro, Gao, Hui, Nagao, Hiroko, Kunigou, Osamu, Komiya, Setsuro

“…The Hedgehog signaling pathway functions as an organizer in embryonic development. Recent studies have demonstrated constitutive activation of Hedgehog pathway…”
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Clinical outcomes of arthroscopic rotator cuff repair: a retrospective comparison of double-layer, double-row and suture bridge methods by Kakoi, Hironori, Izumi, Toshihiko, Fujii, Yasunari, Nagano, Satoshi, Setoguchi, Takao, Ishidou, Yasuhiro, Komiya, Setsuro

“…The suture-bridge (SB) method has recently become the mainstream means of repairing full-thickness rotator cuff tears. However, in some patients the deep and…”
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Tranilast enhances the effect of anticancer agents in osteosarcoma by Nakashima, Takayuki, Nagano, Satoshi, Setoguchi, Takao, Sasaki, Hiromi, Saitoh, Yoshinobu, Maeda, Shingo, Komiya, Setsuro, Taniguchi, Noboru

“…Tranilast [N‑(3',4'‑dimethoxycinnamoyl)‑anthranilic acid], initially developed as an antiallergic drug, also exhibits a growth inhibitory effect on various…”
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Clinical course of the bony lesion of single-system single-site Langerhans cell histiocytosis – Is appropriate follow-up sufficient treatment? by Sasaki, Hiromi, Nagano, Satoshi, Shimada, Hirofumi, Nakamura, Shunsuke, Setoguchi, Takao, Komiya, Setsuro

“…Langerhans cell histiocytosis (LCH) is categorized into three types, which include single-system single-site (SS-s), single-system multiple-site (SS-m) and…”
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Ribosomal protein S3 regulates GLI2-mediated osteosarcoma invasion by Nagao-Kitamoto, Hiroko, Setoguchi, Takao, Kitamoto, Sho, Nakamura, Shunsuke, Tsuru, Arisa, Nagata, Masahito, Nagano, Satoshi, Ishidou, Yasuhiro, Yokouchi, Masahiro, Kitajima, Shinichi, Yoshioka, Takako, Maeda, Shingo, Yonezawa, Suguru, Komiya, Setsuro

“…Highlights • RPS3 was identified as a novel downstream gene of GLI2. • Knockdown of GLI2 decreased RPS3 expression in osteosarcoma cells. • RPS3 knockdown…”
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Accumulation of p62 in degenerated spinal cord under chronic mechanical compression: Functional analysis of p62 and autophagy in hypoxic neuronal cells by Tanabe, Fumito, Yone, Kazunori, Kawabata, Naoya, Sakakima, Harutoshi, Matsuda, Fumiyo, Ishidou, Yasuhiro, Maeda, Shingo, Abematsu, Masahiko, Komiya, Setsuro, Setoguchi, Takao

“…Intracellular accumulation of altered proteins, including p62 and ubiquitinated proteins, is the basis of most neurodegenerative disorders. The relationship…”
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Association between bone mineral density, muscle volume, walking ability, and geriatric nutritional risk index in hemodialysis patients by Tominaga, Hiroyuki, Oku, Manei, Arishima, Yoshiya, Ikeda, Toru, Ishidou, Yasuhiro, Nagano, Satoshi, Minami, Masato, Ido, Akio, Komiya, Setsuro, Setoguchi, Takao

“…Background and Objectives: Hemodialysis patients are at risk for bone loss and sarcopenia, characterized by reduced muscle mass and limited mobility/function…”
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Predictive factors of mortality and deterioration in performance of activities of daily living after hip fracture surgery in Kagoshima, Japan by Ishidou, Yasuhiro, Koriyama, Chihaya, Kakoi, Hironori, Setoguchi, Takao, Nagano, Satoshi, Hirotsu, Masataka, Yamamoto, Takuya, Yokouchi, Masahiro, Komiya, Setsuro

“…Aim Given that different hospitals achieve different outcomes, optimal evaluation of treatment outcomes in the local community requires evaluation of many…”
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GLI2 is a novel therapeutic target for metastasis of osteosarcoma by Nagao‐Kitamoto, Hiroko, Nagata, Masahito, Nagano, Satoshi, Kitamoto, Sho, Ishidou, Yasuhiro, Yamamoto, Takuya, Nakamura, Shunsuke, Tsuru, Arisa, Abematsu, Masahiko, Fujimoto, Yusuke, Yokouchi, Masahiro, Kitajima, Shinichi, Yoshioka, Takako, Maeda, Shingo, Yonezawa, Suguru, Komiya, Setsuro, Setoguchi, Takao

“…Aberrant activation of the Hedgehog (Hh) pathway has been reported in several malignancies. We previously demonstrated that knockdown of GLI2 inhibited…”
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Neurotensin receptor 1 is a new therapeutic target for human undifferentiated pleomorphic sarcoma growth by Tokumoto, Hiroto, Setoguchi, Takao, Saitoh, Yoshinobu, Sasaki, Hiromi, Nagano, Satoshi, Maeda, Shingo, Tanimoto, Akihide, Taniguchi, Noboru

“…Undifferentiated pleomorphic sarcoma (UPS) is the second most common soft tissue sarcoma. For patients with unresectable or metastatic disease, chemotherapies…”
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The histone deacetylase inhibitor LBH589 inhibits undifferentiated pleomorphic sarcoma growth via downregulation of FOS‐like antigen 1 by Saitoh, Yoshinobu, Bureta, Costansia, Sasaki, Hiromi, Nagano, Satoshi, Maeda, Shingo, Furukawa, Tatsuhiko, Taniguchi, Noboru, Setoguchi, Takao

“…Undifferentiated pleomorphic sarcoma (UPS) is the second most frequent soft tissue sarcoma. Because of its resistance to chemotherapy, UPS patients are treated…”
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Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation by Nakamura, Shunsuke, Nagano, Satoshi, Nagao, Hiroko, Ishidou, Yasuhiro, Yokouchi, Masahiro, Abematsu, Masahiko, Yamamoto, Takuya, Komiya, Setsuro, Setoguchi, Takao

“…The Hedgehog pathway is activated in various types of malignancies. We previously reported that inhibition of SMO or GLI prevents osteosarcoma growth in vitro…”
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