Search Results - "SETLOW, Barry"
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Dissociable roles for the basolateral amygdala and orbitofrontal cortex in decision-making under risk of punishment
Published in The Journal of neuroscience (28-01-2015)“…Several neuropsychiatric disorders are associated with abnormal decision-making involving risk of punishment, but the neural basis of this association remains…”
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Contributions of medial prefrontal cortex to decision making involving risk of punishment
Published in Neuropharmacology (01-09-2018)“…The prefrontal cortex (PFC) plays an important role in several forms of cost-benefit decision making. Its contributions to decision making under risk of…”
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Adolescent Risk Taking, Cocaine Self-Administration, and Striatal Dopamine Signaling
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2014)“…Poor decision making and elevated risk taking, particularly during adolescence, have been strongly linked to drug use; however the causal relationships among…”
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4
Optogenetic Inhibition Reveals Distinct Roles for Basolateral Amygdala Activity at Discrete Time Points during Risky Decision Making
Published in The Journal of neuroscience (29-11-2017)“…Decision making is a multifaceted process, consisting of several distinct phases that likely require different cognitive operations. Previous work showed that…”
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Behavioral Characterization of the Effects of Cannabis Smoke and Anandamide in Rats
Published in PloS one (11-04-2016)“…Cannabis is the most widely used illicit drug in the world. Delta-9-tetrahydrocannabinol (Δ9-THC) is the main psychoactive component of cannabis and its…”
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6
Effects of reproductive experience on cost-benefit decision making in female rats
Published in Frontiers in behavioral neuroscience (29-01-2024)“…Many individuals undergo mating and/or other aspects of reproductive experience at some point in their lives, and pregnancy and childbirth in particular are…”
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Undoing cocaine's consequences on behavior and brain
Published in Proceedings of the National Academy of Sciences - PNAS (04-11-2008)Get full text
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8
Dopaminergic modulation of risky decision-making
Published in The Journal of neuroscience (30-11-2011)“…Many psychiatric disorders are characterized by abnormal risky decision-making and dysregulated dopamine receptor expression. The current study was designed to…”
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An ethogram analysis of cutaneous thermal pain sensitivity and oxycodone reward-related behaviors in rats
Published in Scientific reports (28-06-2023)“…Inter-relationships between pain sensitivity, drug reward, and drug misuse are of considerable interest given that many analgesics exhibit misuse potential…”
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Encoding Predicted Outcome and Acquired Value in Orbitofrontal Cortex during Cue Sampling Depends upon Input from Basolateral Amygdala
Published in Neuron (Cambridge, Mass.) (28-08-2003)“…Certain goal-directed behaviors depend critically upon interactions between orbitofrontal cortex (OFC) and basolateral amygdala (ABL). Here we describe direct…”
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11
Testicular hormones mediate robust sex differences in impulsive choice in rats
Published in eLife (28-09-2020)“…Impairments in choosing optimally between immediate and delayed rewards are associated with numerous psychiatric disorders. Such 'intertemporal' choice is…”
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Test‐retest reliability of a new assessment to detect detailed temporal patterns of polysubstance use
Published in International journal of methods in psychiatric research (01-09-2022)“…Objective While polysubstance use is highly prevalent among people who use drugs, the field lacks a reliable assessment that can detect detailed temporal…”
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Effects of acute administration of nicotine, amphetamine, diazepam, morphine, and ethanol on risky decision-making in rats
Published in Psychopharmacologia (01-12-2011)“…Rationale Most individuals can accurately assess the risks and rewards associated with choice alternatives and decide accordingly; however, drug users often…”
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14
Initial characterization of mice null for Lphn3 , a gene implicated in ADHD and addiction
Published in Brain research (29-06-2012)“…Abstract The LPHN3 gene has been associated with both attention deficit-hyperactivity disorder (ADHD) and addiction, suggesting that it may play a role in the…”
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Pharmacokinetics of delta-9-tetrahydrocannabinol following acute cannabis smoke exposure in mice; effects of sex, age, and strain
Published in Frontiers in pharmacology (28-08-2023)“…Increased use of cannabis and cannabinoids for recreational and medical purposes has led to a growth in research on their effects in animal models. The…”
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Affective and cognitive mechanisms of risky decision making
Published in Neurobiology of learning and memory (01-01-2015)“…•Rats chose between small, “safe” rewards and large rewards with risks of shock.•Choice was more sensitive to shock intensity than reward magnitude.•Risk…”
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Different Roles for Orbitofrontal Cortex and Basolateral Amygdala in a Reinforcer Devaluation Task
Published in The Journal of neuroscience (03-12-2003)“…The orbitofrontal cortex (OFC) and basolateral amygdala (BLA) are critical for using learned representations of outcomes to guide behavior. Neurophysiological…”
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Memory-Influencing Intra-Basolateral Amygdala Drug Infusions Modulate Expression of Arc Protein in the Hippocampus
Published in Proceedings of the National Academy of Sciences - PNAS (26-07-2005)“…Activation of β-adrenoceptors in the basolateral complex of the amygdala (BLA) modulates memory storage processes and longterm potentiation in downstream…”
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Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats
Published in eLife (24-04-2019)“…Across species, aging is associated with an increased ability to choose delayed over immediate gratification. These experiments used young and aged rats to…”
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Lesions of orbitofrontal cortex and basolateral amygdala complex disrupt acquisition of odor-guided discriminations and reversals
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-03-2003)“…Recent work indicates that both orbitofrontal cortex (OFC) and the basolateral complex of the amygdala (ABL) are involved in processes by which cues are…”
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