Search Results - "SETIEN, F"

Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis by Anadón, C, Guil, S, Simó-Riudalbas, L, Moutinho, C, Setien, F, Martínez-Cardús, A, Moran, S, Villanueva, A, Calaf, M, Vidal, A, Lazo, P A, Zondervan, I, Savola, S, Kohno, T, Yokota, J, Ribas de Pouplana, L, Esteller, M

“…The introduction of new therapies against particular genetic mutations in non-small-cell lung cancer is a promising avenue for improving patient survival, but…”
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Experiences of nursing students participating in end-of-life education programs: A systematic review and qualitative metasynthesis by Ruiz-Pellón, N., Sarabia-Cobo, C., Amo-Setién, F., Fernández-Peña, R., Abajas, R., Martín, R., Ortego-Mate, C.

“…The aim of this review was to explore the experiences of nursing students participating in end-of-life education programs. A systematic review. Exhaustive…”
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Epigenetic loss of the RNA decapping enzyme NUDT16 mediates C-MYC activation in T-cell acute lymphoblastic leukemia by Anadón, C, van Tetering, G, Ferreira, H J, Moutinho, C, Martínez-Cardús, A, Villanueva, A, Soler, M, Heyn, H, Moran, S, Castro de Moura, M, Setien, F, Vidal, A, Genescà, E, Ribera, J M, Nomdedeu, J F, Guil, S, Esteller, M

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109 A novel Werner Syndrome mutation: Pharmacological treatment by read-through of nonsense mutations and epigenetic therapies by Ruben, A, Achenbach, R, Arocena-Sutz, M, Aldunate, F, Esteller, M, Setien, F

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Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis by Anadón, C, Guil, S, Simó-Riudalbas, L, Moutinho, C, Setien, F, Martínez-Cardús, A, Moran, S, Villanueva, A, Calaf, M, Vidal, A, Lazo, P A, Zondervan, I, Savola, S, Kohno, T, Yokota, J, Ribas de Pouplana, L, Esteller, M

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Unmasking of epigenetically silenced candidate tumor suppressor genes by removal of methyl-CpG-binding domain proteins by Lopez-Serra, L, Ballestar, E, Ropero, S, Setien, F, Billard, L-M, Fraga, M F, Lopez-Nieva, P, Alaminos, M, Guerrero, D, Dante, R, Esteller, M

“…Methyl-cytosine-phosphate-guanine (CpG)-binding domain (MBD) proteins are bound to hypermethylated promoter CpG islands of tumor suppressor genes in human…”
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DNA methylation determines nucleosome occupancy in the 5′-CpG islands of tumor suppressor genes by Portela, A, Liz, J, Nogales, V, Setién, F, Villanueva, A, Esteller, M

“…Promoter CpG island hypermethylation of tumor suppressor genes is an epigenetic hallmark of human cancer commonly associated with nucleosome occupancy and the…”
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Epigenetic inactivation of the ERK inhibitor Spry2 in B-cell diffuse lymphomas by Sánchez, A, Setién, F, Martinez, N, Oliva, J L, Herranz, M, Fraga, M-F, Alaminos, M, Esteller, M, Rojas, J M

“…Spry2 has been characterized as a negative regulator of the extracellular-regulated kinase (ERK) pathway. In this study we analysed whether epigenetic…”
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On the estimation of potential food waste reduction to support sustainable production and consumption policies by Garcia-Herrero, I., Hoehn, D., Margallo, M., Laso, J., Bala, A., Batlle-Bayer, L., Fullana, P., Vazquez-Rowe, I., Gonzalez, M.J., Durá, M.J., Sarabia, C., Abajas, R., Amo-Setien, F.J., Quiñones, A., Irabien, A., Aldaco, R.

“…•Material flow analysis of Spanish food losses and waste (FLW) was conducted.•Estimation of FLW along the supply chain in weight, economic and nutritional…”
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Molecular evolution of the N-formyl peptide and C5a receptors in non-human primates by Alvarez, V, Coto, E, Setién, F, González-Roces, S, López-Larrea, C

“…N-formyl peptides (FMLP) and complement fragment C5a are neutrophil chemoattractants. In humans, a single-copy gene was identified for the C5a receptor, and…”
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A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li–Fraumeni-like families by Calvete, Oriol, Martinez, Paula, Garcia-Pavia, Pablo, Benitez-Buelga, Carlos, Paumard-Hernández, Beatriz, Fernandez, Victoria, Dominguez, Fernando, Salas, Clara, Romero-Laorden, Nuria, Garcia-Donas, Jesus, Carrillo, Jaime, Perona, Rosario, Triviño, Juan Carlos, Andrés, Raquel, Cano, Juana María, Rivera, Bárbara, Alonso-Pulpon, Luis, Setien, Fernando, Esteller, Manel, Rodriguez-Perales, Sandra, Bougeard, Gaelle, Frebourg, Tierry, Urioste, Miguel, Blasco, Maria A., Benítez, Javier

“…Cardiac angiosarcoma (CAS) is a rare malignant tumour whose genetic basis is unknown. Here we show, by whole-exome sequencing of a TP53 -negative…”
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Structural characterization of two CD1A allelic variants by Oteo, Marta, Arribas, Purificación, Setién, Fernando, Parra, Juan F, Mirones, Isabel, Gómez del Moral, Manuel, Martı́nez-Naves, Eduardo

“…CD1 molecules are specialized in presenting lipidic antigens to T lymphocytes. They are structurally and evolutionary related to MHC molecules and show very…”
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Epigenetic Differences Arise during the Lifetime of Monozygotic Twins by Fraga, Mario F., Ballestar, Esteban, Paz, Maria F., Ropero, Santiago, Setien, Fernando, Ballestar, Maria L., Heine-Suñer, Damia, Cigudosa, Juan C., Urioste, Miguel, Benitez, Javier, Boix-Chornet, Manuel, Sanchez-Aguilera, Abel, Ling, Charlotte, Carlsson, Emma, Poulsen, Pernille, Vaag, Allan, Stephan, Zarko, Spector, Tim D., Wu, Yue-Zhong, Plass, Christoph, Esteller, Manel, Gartler, Stanley M.

“…Monozygous twins share a common genotype. However, most monozygotic twin pairs are not identical; several types of phenotypic discordance may be observed, such…”
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Nutritional data management of food losses and waste under a life cycle approach: Case study of the Spanish agri-food system by Garcia-Herrero, I., Margallo, M., Laso, J., Batlle-Bayer, L., Bala, A., Fullana-i-Palmer, P., Vazquez-Rowe, I., Gonzalez, M.J., Amo-Setien, F., Durá, M.J., Sarabia, C., Abajas, R., Quiñones, A., Irabien, A., Aldaco, R.

“…•Nutritional loss & waste for the Spanish food system along the entire supply chain.•48 representative food commodities and 32 nutrients are…”
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A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition by Esteller, Manel, Ropero, Santiago, Fraga, Mario F, Ballestar, Esteban, Hamelin, Richard, Yamamoto, Hiroyuki, Boix-Chornet, Manuel, Caballero, Rosalia, Alaminos, Miguel, Setien, Fernando, Paz, Maria F, Herranz, Michel, Palacios, Jose, Arango, Diego, Orntoft, Torben F, Aaltonen, Lauri A, Schwartz, Simó

“…Disruption of histone acetylation patterns is a common feature of cancer cells, but very little is known about its genetic basis. We have identified truncating…”
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Erratum: Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis by Anadón, C, Guil, S, Simó-Riudalbas, L, Moutinho, C, Setien, F, Martínez-Cardús, A, Moran, S, Villanueva, A, Calaf, M, Vidal, A, Lazo, P A, Zondervan, I, Savola, S, Kohno, T, Yokota, J, Ribas de Pouplana, L, Esteller, M

“…Correction to: Oncogene advance online publication 7 December 2015; doi:10.1038/onc.2015.469 Following the online publication of this article one of the…”
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EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma by ALAMINOS, Miguel, DAVALOS, Veronica, ESTELLER, Manel, ROPERO, Santiago, SETIEN, Fernando, PAZ, Maria F, HERRANZ, Michel, FRAGA, Mario F, MORA, Jaume, CHEUNG, Nai-Kong V, GERALD, William L

“…The presence of common genomic deletions in the 19q13 chromosomal region in neuroblastomas and gliomas strongly suggests the presence of a putative tumor…”
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Inactivation of the Lamin A/C Gene by CpG Island Promoter Hypermethylation in Hematologic Malignancies, and Its Association With Poor Survival in Nodal Diffuse Large B-Cell Lymphoma by Agrelo, Ruben, Setien, Fernando, Espada, Jesus, Artiga, Maria Jesus, Rodriguez, Maria, Pérez-Rosado, Alberto, Sanchez-Aguilera, Abel, Fraga, Mario F, Piris, Miguel Angel, Esteller, Manel

“…Lamins support the nuclear envelope and provide anchorage sites for chromatin, but they are also involved in DNA synthesis, transcription, and apoptosis…”
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Abstract S4-8: Promoter CpG Methylation of BRCA1 Predicts Sensitivity to PARP Inhibitors in Breast Cancer by Veeck, J, Ropero, S, Setien, F, Gonzalez-Suarez, E, Osorio, A, Benitez, J, Herman, JG, Tjan-Heijnen, VC, Esteller, M.

“…Background: Poly(ADP)-ribose polymerase (PARP) inhibitors were shown to selectively kill BRCA1/2 mutated cancer cells due to conferring synthetic lethality,…”
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Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells by Ropero, Santiago, Setien, Fernando, Espada, Jesus, Fraga, Mario F., Herranz, Michel, Asp, Julia, Benassi, Maria Serena, Franchi, Alessandro, Patiño, Ana, Ward, Laura S., Bovee, Judith, Cigudosa, Juan C., Wim, Wuyts, Esteller, Manel

“…Germline mutations in the Exostoses-1 gene (EXT1) are found in hereditary multiple exostoses syndrome, which is characterized by the formation of…”
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