Search Results - "SETAKIS, Efrosini"

Record linkage to enhance consented cohort and routinely collected health data from a UK birth cohort by Tingay, Karen Susan, Bandyopadhyay, Amrita, Griffiths, Lucy, Akbari, Ashley, Brophy, Sinead, Bedford, Helen, Cortina-Borja, Mario, Setakis, Efrosini, Walton, Suzann, Fitzsimons, Emla, Dezateux, Carol, Lyons, Ronan A

“…In longitudinal health research, combining the richness of cohort data to the extensiveness of routine data opens up new possibilities, providing information…”
Get full text

Linking strategies and biases when matching cohorts to the National Pupil Database by Downs, Johnny, Setakis, Efrosini, Mostafa, Tarek, Hayes, Richard, Hotopf, Matthew, Ford, Tamsin, Gilbert, Ruth

“…ABSTRACT Objectives To compare sample biases when linking education data to external datasets using opt in and opt out consent models for the Millennium Cohort…”
Get full text

Combining deterministic and probabilistic matching to reduce data linkage errors in hospital administrative data by Hagger-Johnson, Gareth, Harron, Katie, Aldridge, Rob, Fu, Bo, Setakis, Efrosini, Goldstein, Harvey, Gilbert, Ruth

“…ABSTRACT Objectives Data linkage algorithms are used to link together multiple episodes of care belonging to the same patient. For example, the HESID algorithm…”
Get full text

A genome-wide DNA microsatellite association screen to identify chromosomal regions harboring candidate genes in diabetic nephropathy by MCKNIGHT, Amy Jayne, MAXWELL, A. Peter, SAWCER, Stephen, COMPSTON, Alastair, SETAKIS, Efrosini, PATTERSON, Chris C, BRADY, Hugh R, SAVAGE, David A

“…In an effort to accelerate the identification of susceptibility genes in diabetic nephropathy, the first genome-wide fluorescence-based DNA microsatellite…”
Get full text

Using consented health record linkage in a longitudinal cohort study by Tingay, Karen, Akbari, Ashley, Bandyopadhyay, Amrita, Bedford, Helen, Brophy, Sinead, Cortina Borja, Mario, Fitzsimons, Emla, Griffiths, Lucy, Healy, Melanie, Johnson, Jon, Setakis, Efrosini, Walton, Suzanne, Dezateux, Carol, Lyons, Ronan

“…ABSTRACT Objectives The aim of this project is to address important issues relevant to children’s health This will be done by enhancing information collected…”
Get full text

New candidate loci for multiple sclerosis susceptibility revealed by a whole genome association screen in a Belgian population by Goris, An, Sawcer, Stephen, Vandenbroeck, Koen, Carton, Herwig, Billiau, Alfons, Setakis, Efrosini, Compston, Alastair, Dubois, Bénédicte

“…We have completed a whole genome screen for association with multiple sclerosis (MS) in a Belgian population. The 6000 microsatellite markers provided through…”
Get full text

Risks of stroke and mortality associated with suboptimal anticoagulation in atrial fibrillation patients by Gallagher, A M, Setakis, E, Plumb, J M, Clemens, A, van Staa, T-P

“…Atrial fibrillation (AF) carries an increased risk of ischaemic stroke, and oral anticoagulation with warfarin can reduce this risk. The objective of this…”
Get more information

Early academic achievement in children with isolated clefts: a population-based study in England by Fitzsimons, Kate Jane, Copley, Lynn P, Setakis, Efrosini, Charman, Susan C, Deacon, Scott A, Dearden, Lorraine, van der Meulen, Jan H

“…ObjectivesWe used national data to study differences in academic achievement between 5-year-old children with an isolated oral cleft and the general…”
Get full text

Concomitant use of ibuprofen and paracetamol and the risk of major clinical safety outcomes by De Vries, Frank, Setakis, Efrosini, Van Staa, Tjeerd‐Pieter

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT Non‐steroidal anti‐inflammatory drugs (NSAIDs) and paracetamol are widely used analgesics in the prescription and…”
Get full text

Logistic regression protects against population structure in genetic association studies by Setakis, Efrosini, Stirnadel, Heide, Balding, David J

“…We conduct an extensive simulation study to compare the merits of several methods for using null (unlinked) markers to protect against false positives due to…”
Get full text

Statistical analysis of the GAMES studies by Setakis, Efrosini

Get full text

The pattern of risk of myocardial infarction in patients taking asthma medication: a study with the General Practice Research Database by Zhang, Bill, de Vries, Frank, Setakis, Efrosini, van Staa, Tjeerd-Pieter

“…AIMTo describe the patterns of risks of acute myocardial infarction (MI) during exposure to long-acting beta2-agonists (LABA). METHODSThe study population…”
Get full text

Linking strategies and biases when matching cohorts to the National Pupil Database: IJPDS (2017) Issue 1, Vol 1:348 Proceedings of the IPDLN Conference (August 2016) by Downs, Johnny, Setakis, Efrosini, Mostafa, Tarek, Hayes, Richard, Hotopf, Matthew, Ford, Tamsin, Gilbert, Ruth

“…ABSTRACT ObjectivesTo compare sample biases when linking education data to external datasets using opt in and opt out consent models for the Millennium Cohort…”
Get full text

Combining deterministic and probabilistic matching to reduce data linkage errors in hospital administrative data: IJPDS (2017) Issue 1, Vol 1:296 Proceedings of the IPDLN Conference (August 2016) by Hagger-Johnson, Gareth, Harron, Katie, Aldridge, Rob, Fu, Bo, Setakis, Efrosini, Goldstein, Harvey, Gilbert, Ruth

“…ABSTRACTObjectivesData linkage algorithms are used to link together multiple episodes of care belonging to the same patient. For example, the HESID algorithm…”
Get full text

A whole genome screen for linkage disequilibrium in multiple sclerosis confirms disease associations with regions previously linked to susceptibility by SAWCER, Stephen, MARANIAN, Mel, DEANS, Jackie, GOODFELLOW, Peter N, WALKER, Neil, CLAYTON, David, COMPSTON, Alastair, SETAKIS, Efrosini, CURWEN, Val, AKESSON, Eva, HENSIEK, Anke, CORADDU, Francesca, ROXBURGH, Richard, SAWCER, David, GRAY, Julia

“…Linkage analysis in multiplex families has provisionally identified several genomic regions where genes influencing susceptibility to multiple sclerosis are…”
Get full text

Using consented health record linkage in a longitudinal cohort study: IJPDS (2017) Issue 1, Vol 1:149, Proceedings of the IPDLN Conference (August 2016) by Tingay, Karen, Akbari, Ashley, Bandyopadhyay, Amrita, Bedford, Helen, Brophy, Sinead, Cortina Borja, Mario, Fitzsimons, Emla, Griffiths, Lucy, Healy, Melanie, Johnson, Jon, Setakis, Efrosini, Walton, Suzanne, Dezateux, Carol, Lyons, Ronan

“…ABSTRACT ObjectivesThe aim of this project is to address important issues relevant to children’s health This will be done by enhancing information collected in…”
Get full text

A genome wide scan for association with multiple sclerosis in a N. Irish case control population by Heggarty, Shirley, Sawcer, Stephen, Hawkins, Stanley, McDonnell, Gavin, Droogan, Aidan, Vandenbroeck, Koen, Hutchinson, Michael, Setakis, Efrosini, Compston, Alastair, Graham, Colin

“…In order to screen the genome for linkage disequilibrium (LD) in multiple sclerosis (MS), we typed 2537 microsatellite markers in separately pooled DNA from…”
Get full text

A genomic screen of Spanish multiple sclerosis patients reveals multiple loci associated with the disease by Goertsches, Robert, Villoslada, Pablo, Comabella, Manuel, Montalban, Xavier, Navarro, Arcadi, de la Concha, Emilio G., Arroyo, Rafael, Lopez de Munain, Adolfo, Otaegui, David, Palacios, Ricardo, Perez-Tur, Jordi, Jonasdottir, Aslaug, Benediktsson, Kjartan, Fossdal, Ragnheidur, Sawcer, Stephen, Setakis, Efrosini, Compston, Alastair

“…In order to identify the genomic regions that might confer susceptibility to multiple sclerosis (MS) in the Spanish population, we have performed a genome-wide…”
Get full text

Refining the analysis of a whole genome linkage disequilibrium association map: the United Kingdom results by Yeo, Tai Wai, Roxburgh, Richard, Maranian, Mel, Singlehurst, Sara, Gray, Julia, Hensiek, Anke, Setakis, Efrosini, Compston, Alastair, Sawcer, Stephen

“…Individual genotyping of the 10 most promising markers identified in our previously reported screen for linkage disequilibrium (LD) in multiple sclerosis…”
Get full text

A genome-wide screen for linkage disequilibrium in Sardinian multiple sclerosis by Coraddu, Francesca, Lai, Marina, Mancosu, Cristina, Cocco, Eleonora, Sawcer, Stephen, Setakis, Efrosini, Compston, Alastair, Marrosu, Maria Giovanna

“…Using indirect whole genome association screening, we have searched for multiple sclerosis susceptibility genes in the genetically isolated high risk Sardinian…”
Get full text