Search Results - "SESSA, Fausto"

Effects of 5-fluorouracil on morphology, cell cycle, proliferation, apoptosis, autophagy and ROS production in endothelial cells and cardiomyocytes by Focaccetti, Chiara, Bruno, Antonino, Magnani, Elena, Bartolini, Desirée, Principi, Elisa, Dallaglio, Katiuscia, Bucci, Eraldo O, Finzi, Giovanna, Sessa, Fausto, Noonan, Douglas M, Albini, Adriana

“…Antimetabolites are a class of effective anticancer drugs interfering in essential biochemical processes. 5-Fluorouracil (5-FU) and its prodrug Capecitabine…”
Get full text

The Clinicopathologic Heterogeneity of Grade 3 Gastroenteropancreatic Neuroendocrine Neoplasms: Morphological Differentiation and Proliferation Identify Different Prognostic Categories by Milione, Massimo, Maisonneuve, Patrick, Spada, Francesca, Pellegrinelli, Alessio, Spaggiari, Paola, Albarello, Luca, Pisa, Eleonora, Barberis, Massimo, Vanoli, Alessandro, Buzzoni, Roberto, Pusceddu, Sara, Concas, Laura, Sessa, Fausto, Solcia, Enrico, Capella, Carlo, Fazio, Nicola, La Rosa, Stefano

“…Gastroenteropancreatic (GEP) neuroendocrine carcinomas (NECs) are defined as neuroendocrine neoplasms (NENs) with a Ki-67 index >20% according to the 2010 WHO…”
Get more information

Comprehensive analysis of HPV infection, EGFR exon 20 mutations and LINE1 hypomethylation as risk factors for malignant transformation of sinonasal‐inverted papilloma to squamous cell carcinoma by Sahnane, Nora, Ottini, Giorgia, Turri‐Zanoni, Mario, Furlan, Daniela, Battaglia, Paolo, Karligkiotis, Apostolos, Albeni, Chiara, Cerutti, Roberta, Mura, Eleonora, Chiaravalli, Anna Maria, Castelnuovo, Paolo, Sessa, Fausto, Facco, Carla

“…Different risk factors are suspected to be involved in malignant transformation of sinonasal papillomas and include HPV infection, tobacco smoking,…”
Get full text

Mitochondrial alterations in Parkinson's disease human samples and cellular models by Zilocchi, Mara, Finzi, Giovanna, Lualdi, Marta, Sessa, Fausto, Fasano, Mauro, Alberio, Tiziana

“…Mitochondrial impairment is one of the most important hallmarks of Parkinson's disease (PD) pathogenesis. In this work, we wanted to verify the molecular basis…”
Get full text

Acetyl-L-Carnitine downregulates invasion (CXCR4/CXCL12, MMP-9) and angiogenesis (VEGF, CXCL8) pathways in prostate cancer cells: rationale for prevention and interception strategies by Baci, Denisa, Bruno, Antonino, Cascini, Caterina, Gallazzi, Matteo, Mortara, Lorenzo, Sessa, Fausto, Pelosi, Giuseppe, Albini, Adriana, Noonan, Douglas M

“…Prostate cancer (PCa) is a leading cause of cancer-related death in males worldwide. Exacerbated inflammation and angiogenesis have been largely demonstrated…”
Get full text

Recurrence of immune thrombocytopenia at the time of SARS-CoV-2 infection by Merli, Michele, Ageno, Walter, Sessa, Fausto, Salvini, Marco, Caramazza, Domenica, Mora, Barbara, Rossi, Agostino, Rovelli, Cristina, Passamonti, Francesco, Grossi, Paolo

Get full text

Microsatellite unstable gastrointestinal neuroendocrine carcinomas: a new clinicopathologic entity by Sahnane, Nora, Furlan, Daniela, Monti, Matilde, Romualdi, Chiara, Vanoli, Alessandro, Vicari, Emanuela, Solcia, Enrico, Capella, Carlo, Sessa, Fausto, La Rosa, Stefano

“…Gastroenteropancreatic (GEP) neuroendocrine carcinomas (NECs) and mixed adenoneuroendocrine carcinomas (MANECs) are heterogeneous neoplasms characterized by…”
Get full text

Mixed Adenoneuroendocrine Carcinomas (MANECs) of the Gastrointestinal Tract: An Update by La Rosa, Stefano, Marando, Alessandro, Sessa, Fausto, Capella, Carlo

“…The systematic application of immunohistochemical techniques to the study of tumors has led to the recognition that neuroendocrine cells occur rather…”
Get full text

Ki67 proliferative index of the neuroendocrine component drives MANEC prognosis by Milione, Massimo, Maisonneuve, Patrick, Pellegrinelli, Alessio, Grillo, Federica, Albarello, Luca, Spaggiari, Paola, Vanoli, Alessandro, Tagliabue, Giovanna, Pisa, Eleonora, Messerini, Luca, Centonze, Giovanni, Inzani, Frediano, Scarpa, Aldo, Papotti, Mauro, Volante, Marco, Sessa, Fausto, Fazio, Nicola, Pruneri, Giancarlo, Rindi, Guido, Solcia, Enrico, La Rosa, Stefano, Capella, Carlo

“…Mixed adenoneuroendocrine carcinomas (MANECs) are composed of a poorly differentiated neuroendocrine carcinoma (NEC) and a non-neuroendocrine (non-NEC)…”
Get full text

On the Endless Dilemma of Neuroendocrine Neoplasms of the Breast: a Journey Through Concepts and Entities by Uccella, Silvia, Finzi, Giovanna, Sessa, Fausto, La Rosa, Stefano

“…Neuroendocrine differentiation in breast carcinomas has been a matter of discussion since it was first described almost 60 years ago. Indeed, so-called…”
Get full text

EBV⁺ and MSI Gastric Cancers Harbor High PD-L1/PD-1 Expression and High CD8⁺ Intratumoral Lymphocytes by De Rosa, Simona, Sahnane, Nora, Tibiletti, Maria Grazia, Magnoli, Francesca, Vanoli, Alessandro, Sessa, Fausto, Chiaravalli, Anna Maria

“…Both EBV⁺ and MSI gastric cancers (GCs) have high lymphoid infiltration which is rare in MSS/EBV cancers. PD-L1/PD-1 interaction leads to a down-regulated…”
Get full text

Protective anti-tumor vaccination against glioblastoma expressing the MHC class II transactivator CIITA by Celesti, Fabrizio, Gatta, Andrea, Shallak, Mariam, Chiaravalli, Anna Maria, Cerati, Michele, Sessa, Fausto, Accolla, Roberto S, Forlani, Greta

“…Glioblastoma is the most malignant tumor of the central nervous system. Current treatments based on surgery, chemotherapy, and radiotherapy, and more recently…”
Get full text

EWSR1-ATF1 dependent 3D connectivity regulates oncogenic and differentiation programs in Clear Cell Sarcoma by Möller, Emely, Praz, Viviane, Rajendran, Sanalkumar, Dong, Rui, Cauderay, Alexandra, Xing, Yu-Hang, Lee, Lukuo, Fusco, Carlo, Broye, Liliane C., Cironi, Luisa, Iyer, Sowmya, Rengarajan, Shruthi, Awad, Mary E., Naigles, Beverly, Letovanec, Igor, Ormas, Nicola, Finzi, Giovanna, La Rosa, Stefano, Sessa, Fausto, Chebib, Ivan, Petur Nielsen, G., Digklia, Antonia, Spentzos, Dimitrios, Cote, Gregory M., Choy, Edwin, Aryee, Martin, Stamenkovic, Ivan, Boulay, Gaylor, Rivera, Miguel N., Riggi, Nicolò

“…Oncogenic fusion proteins generated by chromosomal translocations play major roles in cancer. Among them, fusions between EWSR1 and transcription factors…”
Get full text

BRCA Methylation Testing Identifies a Subset of Ovarian Carcinomas without Germline Variants That Can Benefit from PARP Inhibitor by Sahnane, Nora, Carnevali, Ileana, Formenti, Giorgio, Casarin, Jvan, Facchi, Sofia, Bombelli, Raffaella, Di Lauro, Eleonora, Memoli, Domenico, Salvati, Annamaria, Rizzo, Francesca, Sessa, Fausto, Tibiletti, Maria Grazia

“…Homologous Recombination Deficiency (HRD) is a frequent feature of high-grade epithelial ovarian carcinoma (EOC), associated with sensitivity to…”
Get full text

PD-L1 in small bowel adenocarcinoma is associated with etiology and tumor-infiltrating lymphocytes, in addition to microsatellite instability by Giuffrida, Paolo, Arpa, Giovanni, Grillo, Federica, Klersy, Catherine, Sampietro, Gianluca, Ardizzone, Sandro, Fociani, Paolo, Fiocca, Roberto, Latella, Giovanni, Sessa, Fausto, D’Errico, Antonietta, Malvi, Deborah, Mescoli, Claudia, Rugge, Massimo, Nesi, Gabriella, Ferrero, Stefano, Furlan, Daniela, Poggioli, Gilberto, Rizzello, Fernando, Macciomei, Maria C., Santini, Donatella, Volta, Umberto, De Giorgio, Roberto, Caio, Giacomo, Calabrò, Antonio, Ciacci, Carolina, D’Armiento, Maria, Rizzo, Aroldo, Solina, Gaspare, Martino, Michele, Tonelli, Francesco, Villanacci, Vincenzo, Cannizzaro, Renato, Canzonieri, Vincenzo, Florena, Ada M., Biancone, Livia, Monteleone, Giovanni, Caronna, Roberto, Ciardi, Antonio, Elli, Luca, Caprioli, Flavio, Vecchi, Maurizio, D’Incà, Renata, Zingone, Fabiana, D’Odorico, Anna, Lenti, Marco Vincenzo, Oreggia, Barbara, Reggiani Bonetti, Luca, Astegiano, Marco, Biletta, Elena, Cantoro, Laura, Giannone, Antonino G., Orlandi, Augusto, Papi, Claudio, Perfetti, Vittorio, Quaquarini, Erica, Sandri, Giancarlo, Silano, Marco, Usai, Paolo, Barresi, Valeria, Ciccocioppo, Rachele, Luinetti, Ombretta, Pedrazzoli, Paolo, Pietrabissa, Andrea, Viglio, Alessandra, Paulli, Marco, Corazza, Gino R., Solcia, Enrico, Vanoli, Alessandro, Di Sabatino, Antonio

“…Small bowel adenocarcinomas (SBAs) are often associated with poor prognosis and have limited therapeutic options. Programmed cell death protein-1…”
Get full text

Proline Dehydrogenase (PRODH) Is Expressed in Lung Adenocarcinoma and Modulates Cell Survival and 3D Growth by Inducing Cellular Senescence by Grossi, Sarah, Berno, Elena, Chiofalo, Priscilla, Chiaravalli, Anna Maria, Cinquetti, Raffaella, Bruno, Antonino, Palano, Maria Teresa, Gallazzi, Matteo, La Rosa, Stefano, Sessa, Fausto, Acquati, Francesco, Campomenosi, Paola

“…The identification of markers for early diagnosis, prognosis, and improvement of therapeutic options represents an unmet clinical need to increase survival in…”
Get full text

An Italian real-world multicenter study of patients with advanced mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs) of the gastro-entero-pancreatic system treated with chemotherapy by Spada, Francesca, Milione, Massimo, Maisonneuve, Patrick, Prinzi, Natalie, Smiroldo, Valeria, Bolzacchini, Elena, Pusceddu, Sara, Carnaghi, Carlo, Sessa, Fausto, La Rosa, Stefano, Uccella, Silvia, Fazio, Nicola

“…Purpose The aim of this study is to describe the clinical management of an Italian series of patients with advanced gastro-entero-pancreatic (GEP) MiNENs…”
Get full text

ACTH-producing tumorlets and carcinoids of the lung: clinico-pathologic study of 63 cases and review of the literature by La Rosa, Stefano, Volante, Marco, Uccella, Silvia, Maragliano, Roberta, Rapa, Ida, Rotolo, Nicola, Inzani, Frediano, Siciliani, Alessandra, Granone, Pierluigi, Rindi, Guido, Dominioni, Lorenzo, Capella, Carlo, Papotti, Mauro, Sessa, Fausto, Imperatori, Andrea

“…Adrenocorticotropic hormone (ACTH)-secreting lung carcinoids represent the principal cause of ectopic Cushing syndrome, but the prevalence of ACTH expression…”
Get full text

PD-1 (PDCD1) promoter methylation in Merkel cell carcinoma: prognostic relevance and relationship with clinico-pathological parameters by Ricci, Costantino, Morandi, Luca, Righi, Alberto, Gibertoni, Dino, Maletta, Francesca, Ambrosi, Francesca, Agostinelli, Claudio, Uccella, Silvia, Asioli, Silvia, Sessa, Fausto, Pellilli, Maria, Maragliano, Roberta, La Rosa, Stefano, Papotti, Mauro Giulio, Asioli, Sofia

“…Merkel cell carcinoma is an aggressive neuroendocrine skin tumor, for which several non-conclusive prognostic factors of adverse clinical behavior have been…”
Get full text

The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker by Cammarota, Rosaria, Bertolini, Valentina, Pennesi, Giuseppina, Bucci, Eraldo O, Gottardi, Ornella, Garlanda, Cecilia, Laghi, Luigi, Barberis, Massimo C, Sessa, Fausto, Noonan, Douglas M, Albini, Adriana

“…Colorectal cancer can be efficiently treated when found at early stages, thus the search for novel markers is of paramount importance. Since inflammation is…”
Get full text