Search Results - "SESHU, J"

STAS Domain Only Proteins in Bacterial Gene Regulation by Moy, Brian E, Seshu, J

“…Sulfate Transport Anti-Sigma antagonist domains (Pfam01740) are found in all branches of life, from eubacteria to mammals, as a conserved fold encoded by…”
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Tumor Necrosis Factor Alpha Production from CD8⁺ T Cells Mediates Oviduct Pathological Sequelae following Primary Genital Chlamydia muridarum Infection by Murthy, Ashlesh K, Li, Weidang, Chaganty, Bharat K.R, Kamalakaran, Sangamithra, Guentzel, M. Neal, Seshu, J, Forsthuber, Thomas G, Zhong, Guangming, Arulanandam, Bernard P

“…The immunopathogenesis of Chlamydia trachomatis-induced oviduct pathological sequelae is not well understood. Mice genetically deficient in perforin…”
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Borrelia host adaptation Regulator (BadR) regulates rpoS to modulate host adaptation and virulence factors in Borrelia burgdorferi by Miller, Christine L., Karna, S. L. Rajasekhar, Seshu, J.

“…Summary The RpoS transcription factor of Borrelia burgdorferi is a ‘gatekeeper’ because it activates genes required for spirochaetes to transition from tick to…”
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Short-Chain Fatty Acids Alter Metabolic and Virulence Attributes of Borrelia burgdorferi by Lin, Ying-Han, Chen, Yue, Smith, 2nd, Trever C, Karna, S L Rajasekhar, Seshu, J

“…responds to a variety of host-derived factors and appropriately alters its gene expression for adaptation under different host-specific conditions. We…”
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Deletion of BBA64, BBA65, and BBA66 Loci Does Not Alter the Infectivity of Borrelia burgdorferi in the Murine Model of Lyme Disease by Maruskova, Mahulena, Seshu, J

“…Borrelia burgdorferi, the causative agent of Lyme disease, alters its gene expression in response to highly disparate environmental signals encountered in its…”
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Acinetobacter baumannii Gastrointestinal Colonization Is Facilitated by Secretory IgA Which Is Reductively Dissociated by Bacterial Thioredoxin A by Ketter, Patrick M, Yu, Jieh-Juen, Guentzel, M Neal, May, Holly C, Gupta, Rishein, Eppinger, Mark, Klose, Karl E, Seshu, J, Chambers, James P, Cap, Andrew P, Arulanandam, Bernard P

“…Multidrug-resistant is among the most common causes of infectious complications associated with combat-related trauma in military personnel serving overseas…”
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CsrA Modulates Levels of Lipoproteins and Key Regulators of Gene Expression Critical for Pathogenic Mechanisms of Borrelia burgdorferi by Karna, S.L. Rajasekhar, Sanjuan, Eva, Esteve-Gassent, Maria D, Miller, Christine L, Maruskova, Mahulena, Seshu, J

“…Carbon storage regulator A (CsrA) is an RNA binding protein that has been characterized in many bacterial species to play a central regulatory role by…”
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Absence of sodA Increases the Levels of Oxidation of Key Metabolic Determinants of Borrelia burgdorferi by Esteve-Gassent, Maria D, Smith, 2nd, Trever C, Small, Christina M, Thomas, Derek P, Seshu, J

“…Borrelia burgdorferi, the causative agent of Lyme disease, alters its gene expression in response to environmental signals unique to its tick vector or…”
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A Manganese-rich Environment Supports Superoxide Dismutase Activity in a Lyme Disease Pathogen, Borrelia burgdorferi by Aguirre, J.Dafhne, Clark, Hillary M., McIlvin, Matthew, Vazquez, Christine, Palmere, Shaina L., Grab, Dennis J., Seshu, J., Hart, P.John, Saito, Mak, Culotta, Valeria C.

“…The Lyme disease pathogen Borrelia burgdorferi represents a novel organism in which to study metalloprotein biology in that this spirochete has uniquely…”
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Borrelia Host Adaptation Protein (BadP) Is Required for the Colonization of a Mammalian Host by the Agent of Lyme Disease by Smith, Trever C., Helm, Sarah M., Chen, Yue, Lin, Ying-Han, Rajasekhar Karna, S. L., Seshu, J.

“…ABSTRACT Borrelia burgdorferi , the agent of Lyme disease (LD), uses host-derived signals to modulate gene expression during the vector and mammalian phases of…”
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Overexpression of CsrA (BB0184) Alters the Morphology and Antigen Profiles of Borrelia burgdorferi by Sanjuan, Eva, Esteve-Gassent, Maria D, Maruskova, Mahulena, Seshu, J

“…Borrelia burgdorferi, the agent of Lyme disease, alters its gene expression in response to highly disparate environmental signals encountered in its hosts…”
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Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi by Van Laar, Tricia A, Lin, Ying-Han, Miller, Christine L, Karna, S L Rajasekhar, Chambers, James P, Seshu, J

“…Borrelia burgdorferi, the agent of Lyme disease, is a spirochetal pathogen with limited metabolic capabilities that survives under highly disparate…”
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Evaluation of protective and immune responses following vaccination with recombinant MIP and CPAF from Chlamydia abortus as novel vaccines for enzootic abortion of ewes by O'Neill, L.M., Keane, O.M., Ross, P.J., Nally, J.E., Seshu, J., Markey, B.

“…•First description of the use of MIP and CPAF as novel vaccines for EAE.•MIP and CPAF combined offered greater protection than each protein…”
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Inactivation of the fibronectin‐binding adhesin gene bbk32 significantly attenuates the infectivity potential of Borrelia burgdorferi by Seshu, J, Esteve‐Gassent, M. Dolores, Labandeira‐Rey, Maria, Kim, Jung Hwa, Trzeciakowski, Jerome P, Höök, Magnus, Skare, Jonathan T

“…Borrelia burgdorferi, the aetiological agent of Lyme disease, utilizes multiple adhesins to interact with both the arthropod vector and mammalian hosts it…”
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Contributions of Environmental Signals and Conserved Residues to the Functions of Carbon Storage Regulator A of Borrelia burgdorferi by Karna, S L Rajasekhar, Prabhu, Rajesh G, Lin, Ying-Han, Miller, Christine L, Seshu, J

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The Absence of Linear Plasmid 25 or 28-1 of Borrelia burgdorferi Dramatically Alters the Kinetics of Experimental Infection via Distinct Mechanisms by Labandeira-Rey, Maria, Seshu, J, Skare, Jonathan T

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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sodA is essential for virulence of Borrelia burgdorferi in the murine model of Lyme disease by Esteve-Gassent, Maria D, Elliott, Nathaniel L, Seshu, J

“…Borrelia burgdorferi, the causative agent of Lyme disease, has a limited set of genes to combat oxidative/nitrosative stress encountered in its tick vector or…”
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Spermine and Spermidine Alter Gene Expression and Antigenic Profile of Borrelia burgdorferi by Lin, Ying-Han, Romo, Jesus A, Smith, 2nd, Trever C, Reyes, Ann N, Karna, S L Rajasekhar, Miller, Christine L, Van Laar, Tricia A, Yendapally, Raghunandan, Chambers, James P, Seshu, J

“…, the agent of Lyme disease, responds to numerous host-derived signals to alter adaptive capabilities during its enzootic cycle in an arthropod vector and…”
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Antigen-specific CD4+ T cells produce sufficient IFN-gamma to mediate robust protective immunity against genital Chlamydia muridarum infection by Li, Weidang, Murthy, Ashlesh K, Guentzel, M Neal, Seshu, J, Forsthuber, Thomas G, Zhong, Guangming, Arulanandam, Bernard P

“…Chlamydia has been shown to evade host-specific IFN-gamma-mediated bacterial killing; however, IFN-gamma-deficient mice exhibit suboptimal late phase vaginal…”
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Statins reduce spirochetal burden and modulate immune responses in the C3H/HeN mouse model of Lyme disease by Van Laar, Tricia A., Hole, Camaron, Rajasekhar Karna, S.L., Miller, Christine L., Reddick, Robert, Wormley, Floyd L., Seshu, J.

“…Lyme disease (LD) is a systemic disorder caused by Borrelia burgdorferi. Lyme spirochetes encode for a functional 3-hydroxy-3-methyl-glutaryl-coenzyme A…”
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