Search Results - "SERVICE, Susan K"

Variance component model to account for sample structure in genome-wide association studies by Kang, Hyun Min, Sul, Jae Hoon, Service, Susan K, Freimer, Nelson B, Zaitlen, Noah A, Eskin, Eleazar, Sabatti, Chiara, Kong, Sit-yee

“…Eleazar Eskin and colleagues report a variance component model for correcting for sample structure in association studies. The EMMAX program is publicly…”
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Genome-wide association analysis of metabolic traits in a birth cohort from a founder population by Jones, Chris G, Peltonen, Leena, Ripatti, Samuli, Sovio, Ulla, Gabriel, Stacey, Kaakinen, Marika, Varilo, Teppo, Pouta, Anneli, Freimer, Nelson B, Brodsky, Jae, Turunen, Hannu, Hartikainen, Anna-Liisa, Hoggart, Clive, Ruokonen, Aimo, Coin, Lachlan, Service, Susan K, Elliot, Paul, Collins, Andrew, McCarthy, Mark I, Daly, Mark J, Zaitlen, Noah A, Jakkula, Eveliina, Sabatti, Chiara, Järvelin, Marjo-Riitta, Laitinen, Jaana

“…Nelson Freimer and colleagues report the first genome-wide association study of a longitudinal birth cohort (the Northern Finland Birth Cohort 1966). The…”
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The Contribution of GWAS Loci in Familial Dyslipidemias by Ripatti, Pietari, Rämö, Joel T, Söderlund, Sanni, Surakka, Ida, Matikainen, Niina, Pirinen, Matti, Pajukanta, Päivi, Sarin, Antti-Pekka, Service, Susan K, Laurila, Pirkka-Pekka, Ehnholm, Christian, Salomaa, Veikko, Wilson, Richard K, Palotie, Aarno, Freimer, Nelson B, Taskinen, Marja-Riitta, Ripatti, Samuli

“…Familial combined hyperlipidemia (FCH) is a complex and common familial dyslipidemia characterized by elevated total cholesterol and/or triglyceride levels…”
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Geospatial investigations in Colombia reveal variations in the distribution of mood and psychotic disorders by Song, Janet, Ramírez, Mauricio Castaño, Okano, Justin T., Service, Susan K., de la Hoz, Juan, Díaz-Zuluaga, Ana M., Upegui, Cristian Vargas, Gallago, Cristian, Arias, Alejandro, Sánchez, Alexandra Valderrama, Teshiba, Terri, Sabatti, Chiara, Gur, Ruben C., Bearden, Carrie E., Escobar, Javier I., Reus, Victor I., Jaramillo, Carlos Lopez, Freimer, Nelson B., Olde Loohuis, Loes M., Blower, Sally

“…Background Geographical variations in mood and psychotic disorders have been found in upper-income countries. We looked for geographic variation in these…”
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Anatomic brain asymmetry in vervet monkeys by Fears, Scott C, Scheibel, Kevin, Abaryan, Zvart, Lee, Chris, Service, Susan K, Jorgensen, Matthew J, Fairbanks, Lynn A, Cantor, Rita M, Freimer, Nelson B, Woods, Roger P

“…Asymmetry is a prominent feature of human brains with important functional consequences. Many asymmetric traits show population bias, but little is known about…”
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Identifying Heritable Brain Phenotypes in an Extended Pedigree of Vervet Monkeys by Fears, Scott C, Melega, William P, Service, Susan K, Lee, Chris, Chen, Kelly, Tu, Zhuowen, Jorgensen, Matthew J, Fairbanks, Lynn A, Cantor, Rita M, Freimer, Nelson B, Woods, Roger P

“…The area and volume of brain structural features, as assessed by high-resolution three-dimensional magnetic resonance imaging (MRI), are among the most…”
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Characterization of Expression Quantitative Trait Loci in Pedigrees from Colombia and Costa Rica Ascertained for Bipolar Disorder by Peterson, Christine B, Service, Susan K, Jasinska, Anna J, Gao, Fuying, Zelaya, Ivette, Teshiba, Terri M, Bearden, Carrie E, Cantor, Rita M, Reus, Victor I, Macaya, Gabriel, López-Jaramillo, Carlos, Bogomolov, Marina, Benjamini, Yoav, Eskin, Eleazar, Coppola, Giovanni, Freimer, Nelson B, Sabatti, Chiara

“…The observation that variants regulating gene expression (expression quantitative trait loci, eQTL) are at a high frequency among SNPs associated with complex…”
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Clinical and panoramic predictors of femur bone mineral density by WHITE, Stuart C, TAGUCHI, Akira, KAO, David, WU, Sam, SERVICE, Susan K, YOON, Douglas, SUEI, Yoshikazu, NAKAMOTO, Takashi, TANIMOTO, Keiji

“…Dentists are a potentially valuable resource for initial patient screening for signs of osteoporosis, as individuals with osteoporosis have altered…”
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quantitative trait locus for variation in dopamine metabolism mapped in a primate model using reference sequences from related species by Freimer, Nelson B, Service, Susan K, Ophoff, Roel A, Jasinska, Anna J, McKee, Kevin, Villeneuve, Amelie, Belisle, Alexandre, Bailey, Julia N, Breidenthal, Sherry E, Jorgensen, Matthew J, Mann, J. John, Cantor, Rita M, Dewar, Ken, Fairbanks, Lynn A

“…Non-human primates (NHP) provide crucial research models. Their strong similarities to humans make them particularly valuable for understanding complex…”
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Association of structural variation with cardiometabolic traits in Finns by Chen, Lei, Abel, Haley J., Das, Indraniel, Larson, David E., Ganel, Liron, Kanchi, Krishna L., Regier, Allison A., Young, Erica P., Kang, Chul Joo, Scott, Alexandra J., Chiang, Colby, Wang, Xinxin, Lu, Shuangjia, Christ, Ryan, Service, Susan K., Chiang, Charleston W.K., Havulinna, Aki S., Kuusisto, Johanna, Boehnke, Michael, Laakso, Markku, Palotie, Aarno, Ripatti, Samuli, Freimer, Nelson B., Locke, Adam E., Stitziel, Nathan O., Hall, Ira M.

“…The contribution of genome structural variation (SV) to quantitative traits associated with cardiometabolic diseases remains largely unknown. Here, we present…”
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Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk by Yin, Xianyong, Bose, Debraj, Kwon, Annie, Hanks, Sarah C., Jackson, Anne U., Stringham, Heather M., Welch, Ryan, Oravilahti, Anniina, Fernandes Silva, Lilian, Locke, Adam E., Fuchsberger, Christian, Service, Susan K., Erdos, Michael R., Bonnycastle, Lori L., Kuusisto, Johanna, Stitziel, Nathan O., Hall, Ira M., Morrison, Jean, Ripatti, Samuli, Palotie, Aarno, Freimer, Nelson B., Collins, Francis S., Mohlke, Karen L., Scott, Laura J., Fauman, Eric B., Burant, Charles, Boehnke, Michael, Laakso, Markku, Wen, Xiaoquan

“…Transcriptomics data have been integrated with genome-wide association studies (GWASs) to help understand disease/trait molecular mechanisms. The utility of…”
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Dental X-Rays and Risk of Meningioma; the Jury is Still Out by Tetradis, Sotirios, DDS, PhD, White, Stuart C., DDS, PhD, Service, Susan K., MS

“…Article Title and Bibliographic Information Dental x-rays and risk of meningioma. Claus EB, Calvocoressi L, Bondy ML, Schildkraut JM, Wiemels JL, Wrensch M…”
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Genetic contributions to circadian activity rhythm and sleep pattern phenotypes in pedigrees segregating for severe bipolar disorder by Pagani, Lucia, St. Clair, Patricia A., Teshiba, Terri M., Service, Susan K., Fears, Scott C., Araya, Carmen, Araya, Xinia, Bejarano, Julio, Ramirez, Margarita, Castrillón, Gabriel, Gomez-Makhinson, Juliana, Lopez, Maria C., Montoya, Gabriel, Montoya, Claudia P., Aldana, Ileana, Navarro, Linda, Freimer, Daniel G., Safaie, Brian, Keung, Lap-Woon, Greenspan, Kiefer, Chou, Katty, Escobar, Javier I., Ospina-Duque, Jorge, Kremeyer, Barbara, Ruiz-Linares, Andres, Cantor, Rita M., Lopez-Jaramillo, Carlos, Macaya, Gabriel, Molina, Julio, Reus, Victor I., Sabatti, Chiara, Bearden, Carrie E., Takahashi, Joseph S., Freimer, Nelson B.

“…Abnormalities in sleep and circadian rhythms are central features of bipolar disorder (BP), often persisting between episodes. We report here, to our…”
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Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees by Fears, Scott C, Service, Susan K, Kremeyer, Barbara, Araya, Carmen, Araya, Xinia, Bejarano, Julio, Ramirez, Margarita, Castrillón, Gabriel, Gomez-Franco, Juliana, Lopez, Maria C, Montoya, Gabriel, Montoya, Patricia, Aldana, Ileana, Teshiba, Terri M, Abaryan, Zvart, Al-Sharif, Noor B, Ericson, Marissa, Jalbrzikowski, Maria, Luykx, Jurjen J, Navarro, Linda, Tishler, Todd A, Altshuler, Lori, Bartzokis, George, Escobar, Javier, Glahn, David C, Ospina-Duque, Jorge, Risch, Neil, Ruiz-Linares, Andrés, Thompson, Paul M, Cantor, Rita M, Lopez-Jaramillo, Carlos, Macaya, Gabriel, Molina, Julio, Reus, Victor I, Sabatti, Chiara, Freimer, Nelson B, Bearden, Carrie E

“…Genetic factors contribute to risk for bipolar disorder (BP), but its pathogenesis remains poorly understood. A focus on measuring multisystem quantitative…”
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MAINTENANCE OF GENETIC VARIATION IN HUMAN PERSONALITY: TESTING EVOLUTIONARY MODELS BY ESTIMATING HERITABILITY DUE TO COMMON CAUSAL VARIANTS AND INVESTIGATING THE EFFECT OF DISTANT INBREEDING by Verweij, Karin J.H., Yang, Jian, Lahti, Jari, Veijola, Juha, Hintsanen, Mirka, Pulkki-Råback, Laura, Heinonen, Kati, Pouta, Anneli, Pesonen, Anu-Katriina, Widen, Elisabeth, Taanila, Anja, Isohanni, Matti, Miettunen, Jouko, Palotie, Aarno, Penke, Lars, Service, Susan K., Heath, Andrew C., Montgomery, Grant W., Raitakari, Olli, Kähönen, Mika, Viikari, Jorma, Räikkönen, Katri, Eriksson, Johan G, Keltikangas-Järvinen, Liisa, Lehtimäki, Terho, Martin, Nicholas G., Järvelin, Marjo-Riitta, Visscher, Peter M., Keller, Matthew C., Zietsch, Brendan P.

“…Personality traits are basicdimensions of behavioral variation, and twin, family, and adoption studies show that around 30% of the between-individual variation…”
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Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate by Jasinska, Anna J, Zelaya, Ivette, Service, Susan K, Peterson, Christine B, Cantor, Rita M, Choi, Oi-Wa, DeYoung, Joseph, Eskin, Eleazar, Fairbanks, Lynn A, Fears, Scott, Furterer, Allison E, Huang, Yu S, Ramensky, Vasily, Schmitt, Christopher A, Svardal, Hannes, Jorgensen, Matthew J, Kaplan, Jay R, Villar, Diego, Aken, Bronwen L, Flicek, Paul, Nag, Rishi, Wong, Emily S, Blangero, John, Dyer, Thomas D, Bogomolov, Marina, Benjamini, Yoav, Weinstock, George M, Dewar, Ken, Sabatti, Chiara, Wilson, Richard K, Jentsch, J David, Warren, Wesley, Coppola, Giovanni, Woods, Roger P, Freimer, Nelson B

“…Nelson Freimer and colleagues analyze gene expression data from multiple tissue samples combined with genotype data from vervet monkeys to catalog expression…”
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Genome-wide mapping of brain phenotypes in extended pedigrees with strong genetic loading for bipolar disorder by Fears, Scott C., Service, Susan K., Kremeyer, Barbara, Araya, Carmen, Araya, Xinia, Bejarano, Julio, Ramirez, Margarita, Castrillón, Gabriel, Gomez-Franco, Juliana, Lopez, Maria C., Montoya, Gabriel, Montoya, Patricia, Aldana, Ileana, Teshiba, Terri M., Al-Sharif, Noor B., Jalbrzikowski, Maria, Tishler, Todd A., Escobar, Javier, Ruiz-Linares, Andrés, Lopez-Jaramillo, Carlos, Macaya, Gabriel, Molina, Julio, Reus, Victor I., Cantor, Rita M., Sabatti, Chiara, Freimer, Nelson B., Bearden, Carrie E.

“…Bipolar disorder is a highly heritable illness, associated with alterations of brain structure. As such, identification of genes influencing inter-individual…”
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Brain structure-function associations in multi-generational families genetically enriched for bipolar disorder by Fears, Scott C, Schür, Remmelt, Sjouwerman, Rachel, Service, Susan K, Araya, Carmen, Araya, Xinia, Bejarano, Julio, Knowles, Emma, Gomez-Makhinson, Juliana, Lopez, Maria C, Aldana, Ileana, Teshiba, Terri M, Abaryan, Zvart, Al-Sharif, Noor B, Navarro, Linda, Tishler, Todd A, Altshuler, Lori, Bartzokis, George, Escobar, Javier I, Glahn, David C, Thompson, Paul M, Lopez-Jaramillo, Carlos, Macaya, Gabriel, Molina, Julio, Reus, Victor I, Sabatti, Chiara, Cantor, Rita M, Freimer, Nelson B, Bearden, Carrie E

“…Recent theories regarding the pathophysiology of bipolar disorder suggest contributions of both neurodevelopmental and neurodegenerative processes. While…”
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A Complete Genome Screen for Genes Predisposing to Severe Bipolar Disorder in Two Costa Rican Pedigrees by McInnes, L. Alison, Escamilla, Michael A., Service, Susan K., Reus, Victor I., Leon, Pedro, Silva, Sandra, Rojas, Eugenia, Spesny, Mitzi, Baharloo, Siamak, Blankenship, Kathleen, Peterson, Amy, Tyler, David, Shimayoshi, Norito, Tobey, Christa, Batki, Steven, Vinogradov, Sophia, Meza, Luis, Gallegos, Alvaro, Fournier, Eduardo, Smith, Lauren B., Barondes, Samuel H., Sandkuijl, Lodewijk A., Freimer, Nelson B.

“…Bipolar mood disorder (BP) is a debilitating syndrome characterized by episodes of mania and depression. We designed a multistage study to detect all major…”
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Systems Biology of the Vervet Monkey by Jasinska, Anna J., Schmitt, Christopher A., Service, Susan K., Cantor, Rita M., Dewar, Ken, Jentsch, James D., Kaplan, Jay R., Turner, Trudy R., Warren, Wesley C., Weinstock, George M., Woods, Roger P., Freimer, Nelson B.

“…Nonhuman primates (NHP) provide crucial biomedical model systems intermediate between rodents and humans. The vervet monkey (also called the African green…”
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