Search Results - "SERRANO, Alvaro"

Methods of Inactivation of SARS-CoV-2 for Downstream Biological Assays by Patterson, Edward I, Prince, Tessa, Anderson, Enyia R, Casas-Sanchez, Aitor, Smith, Shirley L, Cansado-Utrilla, Cintia, Solomon, Tom, Griffiths, Michael J, Acosta-Serrano, Álvaro, Turtle, Lance, Hughes, Grant L

“…The scientific community has responded to the coronavirus disease 2019 (COVID-19) pandemic by rapidly undertaking research to find effective strategies to…”
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Waves of novelties in the expansion into the adjacent possible by Monechi, Bernardo, Ruiz-Serrano, Ãlvaro, Tria, Francesca, Loreto, Vittorio

“…The emergence of novelties and their rise and fall in popularity is an ubiquitous phenomenon in human activities. The coexistence of popular evergreens with…”
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Neuronal P2X7 Receptor: Involvement in Neuronal Physiology and Pathology by Miras-Portugal, M Teresa, Sebastián-Serrano, Álvaro, de Diego García, Laura, Díaz-Hernández, Miguel

“…The proposed presence of P2X7 receptor (P2X7R) in neurons has been the source of some contention. Initial studies suggested an absence of P2X7R mRNA in…”
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P2X7 receptor blockade reduces tau induced toxicity, therapeutic implications in tauopathies by Di Lauro, Caterina, Bianchi, Carolina, Sebastián-Serrano, Álvaro, Soria-Tobar, Lucia, Alvarez-Castelao, Beatriz, Nicke, Annette, Díaz-Hernández, Miguel

“…•Tauopathy patients and mouse model P301S present P2X7R upregulation in glial cells.•Pharmacological or genetic P2X7 blockade reverts microglial activation in…”
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A new perspective on cutaneous leishmaniasis-Implications for global prevalence and burden of disease estimates by Bailey, Freddie, Mondragon-Shem, Karina, Hotez, Peter, Ruiz-Postigo, José Antonio, Al-Salem, Waleed, Acosta-Serrano, Álvaro, Molyneux, David H

“…About the Authors: Freddie Bailey Affiliations NTDs, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom, University of Edinburgh…”
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The Neurotoxic Role of Extracellular Tau Protein by Sebastián-Serrano, Álvaro, de Diego-García, Laura, Díaz-Hernández, Miguel

“…Tauopathies are a class of neurodegenerative diseases associated with the microtubule-associated protein tau, with Alzheimer's disease (AD) being the most…”
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A neglected among the neglected: a review of cutaneous leishmaniasis in Guatemala by Lopez, Yaimie, Arana, Byron, Rizzo, Nidia, Duran, Erick, Acosta-Serrano, Álvaro, Mendizabal-Cabrera, Renata

“…Cutaneous leishmaniasis (CL) is a parasitic vector-borne disease affecting mostly low- and middle-income countries. CL is endemic in Guatemala, where an…”
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P2X7 receptor inhibition ameliorates ubiquitin-proteasome system dysfunction associated with Alzheimer's disease by Bianchi, Carolina, Alvarez-Castelao, Beatriz, Sebastián-Serrano, Álvaro, Di Lauro, Caterina, Soria-Tobar, Lucia, Nicke, Annette, Engel, Tobias, Díaz-Hernández, Miguel

“…Over recent years, increasing evidence suggests a causal relationship between neurofibrillary tangles (NFTs) formation, the main histopathological hallmark of…”
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Tsetse flies ( Glossina morsitans morsitans ) choose birthing sites guided by substrate cues with no evidence for a role of pheromones by Adden, Andrea K, Haines, Lee R, Acosta-Serrano, Álvaro, Prieto-Godino, Lucia L

“…Tsetse flies significantly impact public health and economic development in sub-Saharan African countries by transmitting the fatal disease African…”
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Cutaneous leishmaniasis and co-morbid major depressive disorder: A systematic review with burden estimates by Bailey, Freddie, Mondragon-Shem, Karina, Haines, Lee Rafuse, Olabi, Amina, Alorfi, Ahmed, Ruiz-Postigo, José Antonio, Alvar, Jorge, Hotez, Peter, Adams, Emily R, Vélez, Iván D, Al-Salem, Waleed, Eaton, Julian, Acosta-Serrano, Álvaro, Molyneux, David H

“…Major depressive disorder (MDD) associated with chronic neglected tropical diseases (NTDs) has been identified as a significant and overlooked contributor to…”
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Discovery of a Novel DYRK1A Mutation (c.524del) in Intellectual Development Disorder Autosomal Dominant 7 (MRD7): A Comprehensive Case Analysis by Whitaker, Fiona, Serrano, Alvaro

“…Dual-specificity tyrosine kinase 1A (DYRK1A) is a member of the CMGC family that is linked to a multitude of neuronal development pathways. Both overexpression…”
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Cux1 and Cux2 Regulate Dendritic Branching, Spine Morphology, and Synapses of the Upper Layer Neurons of the Cortex by Cubelos, Beatriz, Sebastián-Serrano, Alvaro, Beccari, Leonardo, Calcagnotto, Maria Elisa, Cisneros, Elsa, Kim, Seonhee, Dopazo, Ana, Alvarez-Dolado, Manuel, Redondo, Juan Miguel, Bovolenta, Paola, Walsh, Christopher A., Nieto, Marta

“…Dendrite branching and spine formation determines the function of morphologically distinct and specialized neuronal subclasses. However, little is known about…”
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Amyloid Peptide Induced Neuroinflammation Increases the P2X7 Receptor Expression in Microglial Cells, Impacting on Its Functionality by Martínez-Frailes, Carlos, Di Lauro, Caterina, Bianchi, Carolina, de Diego-García, Laura, Sebastián-Serrano, Álvaro, Boscá, Lisardo, Díaz-Hernández, Miguel

“…Alzheimer disease is a neurodegenerative disease characterized by the presence of senile plaques composed of amyloid-β (Aβ) peptide, neurofibrillary tangles,…”
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The Role of P2X7 Receptor in Alzheimer’s Disease by Francistiová, Linda, Bianchi, Carolina, Di Lauro, Caterina, Sebastián-Serrano, Álvaro, de Diego-García, Laura, Kobolák, Julianna, Dinnyés, András, Díaz-Hernández, Miguel

“…Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease characterized by a progressive cognitive decline associated with global brain damage…”
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Kidins220 deficiency causes ventriculomegaly via SNX27-retromer-dependent AQP4 degradation by del Puerto, Ana, Pose-Utrilla, Julia, Simón-García, Ana, López-Menéndez, Celia, Jiménez, Antonio J., Porlan, Eva, Pajuelo, Luis S. M., Cano-García, Guillermo, Martí-Prado, Beatriz, Sebastián-Serrano, Álvaro, Sánchez-Carralero, Marina P., Cesca, Fabrizia, Schiavo, Giampietro, Ferrer, Isidro, Fariñas, Isabel, Campanero, Miguel R., Iglesias, Teresa

“…Several psychiatric, neurologic and neurodegenerative disorders present increased brain ventricles volume, being hydrocephalus the disease with the major…”
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Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation by Sebastián-Serrano, Álvaro, Engel, Tobias, de Diego-García, Laura, Olivos-Oré, Luis A, Arribas-Blázquez, Marina, Martínez-Frailes, Carlos, Pérez-Díaz, Carmen, Millán, José Luis, Artalejo, Antonio R, Miras-Portugal, María Teresa, Henshall, David C, Díaz-Hernández, Miguel

“…Hypomorphic mutations in the gene encoding the tissue-nonspecific alkaline phosphatase (TNAP) enzyme, ALPL in human or Akp2 in mice, cause hypophosphatasia…”
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Heteroatom Effect on Star‐Shaped Hole‐Transporting Materials for Perovskite Solar Cells by García‐Benito, Inés, Zimmermann, Iwan, Urieta‐Mora, Javier, Aragó, Juan, Calbo, Joaquín, Perles, Josefina, Serrano, Alvaro, Molina‐Ontoria, Agustín, Ortí, Enrique, Martín, Nazario, Nazeeruddin, Mohammad Khaja

“…Three new star‐shaped hole‐transporting materials (HTMs) incorporating benzotripyrrole, benzotrifuran, and benzotriselenophene central cores endowed with…”
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Caught in a trap: DNA contamination in tsetse xenomonitoring can lead to over-estimates of Trypanosoma brucei infection by Saldanha, Isabel, Lea, Rachel, Manangwa, Oliver, Garrod, Gala, Haines, Lee R, Acosta-Serrano, Álvaro, Auty, Harriet, Betson, Martha, Lord, Jennifer S, Morrison, Liam J, Mramba, Furaha, Torr, Stephen J, Cunningham, Lucas J

“…Tsetse flies (Glossina sp.) are vectors of Trypanosoma brucei subspecies that cause human African trypanosomiasis (HAT). Capturing and screening tsetse is…”
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Modulus of rupture prediction in Pinus sylvestris with multivariate models constructed with resonance, ultrasound, and wood heterogeneity variables by Fernández-Serrano, Álvaro, Villasante, Antonio

“…Multivariate models with multiple linear regression (MLR), artificial neural network (ANN), and k-nearest neighbors (KNN) were developed to predict the modulus…”
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Differential regulation of Kidins220 isoforms in Huntington's disease by Sebastián‐Serrano, Álvaro, Simón‐García, Ana, Belmonte‐Alfaro, Alicia, Pose‐Utrilla, Julia, Santos‐Galindo, María, del Puerto, Ana, García‐Guerra, Lucía, Hernández, Ivó H., Schiavo, Giampietro, Campanero, Miguel R., Lucas, José J., Iglesias, Teresa

“…Huntington's disease (HD) is an inherited progressive neurodegenerative disease characterized by brain atrophy particularly in the striatum that produces motor…”
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